Leopardus geoffroyi (Geoffroy's cat): 123603771
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Entry
123603771 CDS
T10761
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein isoform X1
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
lgf Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf01524
Platinum drug resistance
lgf03440
Homologous recombination
lgf03460
Fanconi anemia pathway
lgf04120
Ubiquitin mediated proteolysis
lgf04151
PI3K-Akt signaling pathway
lgf05206
MicroRNAs in cancer
lgf05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
lgf00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
123603771 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
123603771 (BRCA1)
03460 Fanconi anemia pathway
123603771 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
123603771 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
123603771 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
123603771 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
123603771 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
lgf01009
]
123603771 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
lgf04121
]
123603771 (BRCA1)
03036 Chromosome and associated proteins [BR:
lgf03036
]
123603771 (BRCA1)
03400 DNA repair and recombination proteins [BR:
lgf03400
]
123603771 (BRCA1)
Enzymes [BR:
lgf01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
123603771 (BRCA1)
Protein phosphatases and associated proteins [BR:
lgf01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
123603771 (BRCA1)
Ubiquitin system [BR:
lgf04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
123603771 (BRCA1)
Multi subunit type E3
BRCC complex
123603771 (BRCA1)
Chromosome and associated proteins [BR:
lgf03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
123603771 (BRCA1)
DNA repair and recombination proteins [BR:
lgf03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
123603771 (BRCA1)
BRCA1-A complex
123603771 (BRCA1)
BRCA1-B complex
123603771 (BRCA1)
BRCA1-C complex
123603771 (BRCA1)
BRCA complex
123603771 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
123603771 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
zf-C3HC4_2
zf-RING_UBOX
zf-C3HC4_4
zf-C3HC4_3
zf-RING_2
zf-RING_5
RING_XB3-XBAT31
zf-Nse
zf-RING_6
BRCT_2
zf-ANAPC11
zf-RING_10
zf-rbx1
RTT107_BRCT_5
Prok-RING_4
KIF21A
Motif
Other DBs
NCBI-GeneID:
123603771
NCBI-ProteinID:
XP_045344963
LinkDB
All DBs
Position
E1:complement(41443601..41506433)
Genome browser
AA seq
1873 aa
AA seq
DB search
MDLSADRVEEVQSVLNAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQRKGPSQ
CPLCKNDITKRSLQESTRFSQLVEELLNIIHAFELDTGLQFANSYNFSKKENNSPEHLKE
EVSIIQSMGYRNRAKRLRQSEPENPSLETSLSVQLSNFGIVRSLRTKQQIQPQNKSVYIE
LGSDSSEDTVNKTSYFSVGDDELLGITPQGARAEASLNPAKKASCEFSEDLTNIEHRQPS
NKDLTATEKHATEKHPEKYQGISVSNLHVEPCATNTHASSLQHENSSLLLTKDRMNVEKA
EFCNESKQPGVARSQQSRWAESKETCNDRQTPSTEKKVVLNADPLCRRKLSKQKSPCSDS
PRDSQDVPWITLNSSIQKVNEWFSRSDEMLTSDDSHNGGSESNPGVAGAVEVPNVVDGYS
GSSEKIDLMASDPHDALICESERVHTKPVESNIEDKIFGKTYRRKASLPNLSHTSEDLII
GACAIEPQITQAHPLTNKTKCKRRSTAGLHPEDFIKKVDLAIVQKTPEKLIEGTDRIGQN
GHVMNITNNGPENGTKGDYVQKEKNAKPTESLEKESAFRTKAEPISSNISNMESELNSHS
SRAPKENRLRRKSSTRHMRALELVVNRNPSPPDHTELQIDSCSSSEEMVKRKSSEQMLVR
HSKTLQLVENKEPAPGAKKRNKPSKQINKRLASNTFPELNLTNIPGVFTNCSSSNTLKEF
VNPGIQREELEESRGTIHVSNRTRDPKELVSSGGRSLQTERSVESTSISLVPDADYGTQD
SISLLEADTLGKAKTAPNQHVSLCAAIENPKEAIHGCSKDTRNGTEGFTDPLRREDNHTQ
ETSIEMEENELDTQCLYNMFKVSKRQSFALFSNPGNPEKECATVWARSTSLRKQSPKVAL
EYEQKEENQGKKQSEIKHVQAVRATAGFSAVSQKVEKPGDYAKCSIKGVPGLCQSSQLRG
NETELFIANNHDISKNPYHIPPLSPIRSSVNAVCKKNLSEEKFEQRSMSPERAVGNESVI
QSTVSTISQNNIRENTFKEVSSSSVNEVGSSANEVGSSINEVGSSGENIQTELGRNRGPK
LSAMLRLGLMQPEVYEQSLPISNCKCPEMKRQGENEGVVQSVNADFSPCLISDNVEQPME
SSRASQVCSETPNDLLNGDEIKGKISFAESAKERSAVFRKSVQKGEFRRSPSPLDHTHLA
QGHQTETRKLESSEENVSSEEEELPCFQHLLFGKVTSIPSQSTSHNAIATEGLSKKTEAN
LESLKDSLHDCSNQVTSAKESQEHHHSEEARCSGSLFSSQCSASEDSAVNTNTQDPFLMF
DPPSKQVRHQSENVDVLSDEELVSYDDEREPGLEEDNHEEEQSVDSNLGEAASGYESETS
LSEDCSGVSSQSDILTTQQRDTMQDNLIKLQQEMAELEAVLEQHESQPSNSSPALITDSY
APEDLFNLGQNTSEKAVLTSEKSSDCLISQNPESLSADKFQVSMDSSTSKTKEPGMRRSS
PSQSRLLDTRQCVRSHSSSLQSTNCLSQKELIKAVDGEELQLTKSEPRDFMEQSYLPRQD
LEGTPYFESGVSLFSDDPESDLSVDRAPEPVHVSSMPTSTSALKLPQFQVEESAKSTAAV
HITNTAGYNKREDIEGKEKPETMSSTKRVNKRISMVASGLTPKELVLVQKFARRHQITLT
NVISEETTHVIMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLDEHDFEVR
GDVVNGRNHQGPKRARESRDRKIFGGLEICCYGPFSNMATDQLEWMVRLCGASVVKRPSL
FTLSKATHPIVVVQPDAWTEDSGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQ
IPRATADLSQPCV
NT seq
5622 nt
NT seq
+upstream
nt +downstream
nt
atggatttatctgcagatcgtgttgaagaagtacaaagtgtccttaatgctatgcagaaa
atcttagagtgtccaatctgtctggagttgatcaaagagcctgtttccacaaagtgtgat
cacatattttgcaaattttgtatgctgaaacttctcaaccagaggaaagggccttcacag
tgtcctttgtgtaagaatgatataaccaaaagaagcctacaggaaagtacaagatttagt
caacttgttgaagagctgttgaacatcattcatgcttttgagcttgacacaggattgcag
tttgcaaacagctataacttttcaaaaaaggaaaataactctcctgagcatctgaaggag
gaggtttctattatccaaagtatgggctatcgaaaccgtgctaaaagacttcgacagagt
gaacctgaaaaccctagcttggaaaccagtcttagtgtccaactctctaactttggaatt
gtgagatctctgaggacaaagcagcagatacaaccacagaataagtctgtctacattgaa
ttgggatctgattcttctgaagataccgtgaataagacaagttatttcagtgtgggagat
gacgaattgttaggaatcacccctcaaggagccagagctgaagccagtttgaatcctgca
aaaaaggcctcttgtgaattttctgaggacctaacaaatattgaacatcgtcaacccagt
aataaagatttgaccgccactgagaagcatgcaactgaaaagcatccagaaaagtatcag
ggtatttctgtttcaaacttgcatgtggagccatgtgccacaaatactcatgccagctca
ttacagcatgagaacagcagtttattactcactaaagacagaatgaatgtagaaaaggct
gaattctgtaatgaaagcaaacagcctggcgtagcaaggagccaacagagcagatgggct
gaaagtaaggaaacatgtaatgataggcagactcccagcacagagaaaaaggtagttctg
aatgctgatcccctgtgtaggagaaaactgagtaagcagaaatctccatgctctgacagt
cctagagattcccaagatgtaccttggataacactgaatagtagcatacagaaagttaat
gagtggttttccagaagtgatgaaatgttaacttctgatgactcacataatgggggatct
gaatcgaatcctggagtagctggtgcagtagaagttccaaatgtagtggatggatattct
ggttcttctgagaaaatagacttaatggccagtgatcctcatgatgctttgatatgtgaa
agtgaaagagtccacaccaaaccagtagagagtaatattgaagataaaatatttgggaaa
acctatcggaggaaggcaagccttcctaacttgagccacacaagtgaagatctcattata
ggagcatgtgctatagaacctcagataacgcaagcccatcccctcacaaataaaacaaag
tgtaaaaggagatctactgcaggccttcatcctgaggattttatcaagaaagtagatttg
gccattgttcaaaagactcctgaaaagctaattgagggaactgatcgaatagggcaaaac
ggtcatgtgatgaatataacaaataatggtcctgagaatgggacaaaaggtgattatgtt
cagaaagagaaaaatgctaagccaacagaatcattggaaaaagaatctgcttttagaacc
aaagctgaaccaataagcagcaatataagtaatatggaatcagaattaaatagccacagt
tcaagggcacctaaggagaacaggttgaggaggaagtcctctaccaggcacatgcgtgcg
ctggaattagtagtcaatagaaatccaagcccacctgatcataccgaactacagattgat
agttgttctagcagtgaagagatggtgaaaagaaaaagttcggaacaaatgctagtcaga
cacagcaaaacacttcaactcgtggaaaataaagaacctgcacctggagccaagaagcgt
aacaagccaagtaaacaaataaataaaagacttgccagtaacacttttccggagctaaat
ttaacaaacatacctggggtttttactaactgttcaagttctaatacacttaaagagttt
gtcaaccctggcattcaaagagaagaactagaagagagccgaggaacgattcatgtgtct
aataggaccagagatcccaaagagctggtatcgagtggaggaagaagtttgcaaactgaa
agatctgtagagagtaccagtatttcattggtacctgatgccgattatggcactcaggat
agtatctcattactggaagctgacaccctagggaaggcaaaaacagcaccaaatcaacat
gtgagtctgtgtgcagcaattgaaaaccccaaggaagctatccatggttgttccaaagat
actagaaatggcacagagggttttacagatcctctgagacgtgaagataaccatactcag
gagacaagtatagaaatggaagagaatgaacttgatacgcagtgtttatacaatatgttc
aaggtttcaaaacgtcagtcatttgctctgttttcaaatccaggaaatccagaaaaggaa
tgtgctacagtctgggcccgttccacgtccttaaggaaacaaagtccaaaagtcgctctt
gaatatgaacaaaaagaagaaaatcagggaaagaaacagtccgaaatcaagcacgtgcag
gcagtccgtgcaactgcaggcttttctgcagtcagtcagaaagtggagaagccaggtgat
tatgccaaatgtagcataaaaggagtccctgggctctgtcagtcatctcagttgagaggc
aatgaaactgaactctttattgcaaataaccatgacatttcaaaaaacccttatcatata
ccaccactttctcccatcagatcatctgttaatgctgtatgtaagaaaaacctgtcagag
gaaaagtttgagcagcgttcaatgtcacctgaaagagcagtgggaaatgagagcgtcatt
caaagtacagtgagcacaattagccaaaataacattagagaaaacacttttaaagaagtt
agctcaagcagtgttaatgaagtaggttccagtgctaatgaagtaggctctagcattaat
gaagtaggttccagtggtgaaaacattcaaacagaactgggtagaaaccgaggacctaag
ttaagtgctatgctcaggttaggtcttatgcaacctgaagtctatgagcaaagtcttcct
ataagtaattgtaaatgtccagaaatgaaaaggcaaggagaaaatgaaggagtagttcag
tctgttaatgcagatttttctccatgtctaatttccgataatgtagaacaacctatggaa
agtagccgtgcttctcaggtttgttctgagacacccaatgacctattaaatggtgatgaa
ataaagggaaaaatcagctttgctgaaagtgctaaggaaagatctgctgtttttcgcaag
agtgtccagaaaggagaattcagaaggagccctagccctttagaccatacacatctggct
cagggtcaccaaacagagaccaggaagttagagtcctcagaagagaacgtgtctagtgag
gaggaagagcttccctgcttccaacacttactatttggtaaagtaaccagtataccttct
cagtctaccagccataatgccattgccacggagggtctgtctaagaaaacagaggcgaac
ctagaatcattgaaggatagcttacatgactgcagtaaccaggtaacatcagcaaaggag
tcccaggaacatcaccatagtgaggaagcgaggtgttccggtagcttattttcttcacag
tgcagtgcatcggaagactcggctgttaatacaaatacccaggatcctttcttgatgttt
gatcctccttccaaacaagtgaggcatcagtccgaaaatgtggacgttctgagtgatgag
gaattggtttcatatgatgatgaaagggaacctggcctggaagaggataatcacgaagaa
gagcagagtgtggattcaaacttaggtgaagcggcatctgggtacgagagtgaaacaagc
ctctctgaagactgttcaggggtgtcctctcagagtgatattttaaccactcagcagagg
gataccatgcaagacaacctgatcaagctccagcaggaaatggccgaactggaagccgtg
ttagagcagcacgagagccagccttctaacagctcccctgccctcataacagattcttat
gcccctgaggacctgttcaatctgggacaaaacacatcagagaaagcagtattaacttca
gagaaaagtagtgactgccttataagccagaatcccgaaagcctctctgctgacaaattt
caagtatctatggatagttccaccagtaaaactaaagaaccgggaatgagaaggtcttct
ccttctcaatcccggctgttagatactaggcagtgtgtgcgcagccactcaagcagtctt
cagagcacaaactgcctgtctcagaaggagctaattaaggctgtcgatggggaggagcta
caactgactaagtcagagccccgagatttcatggagcagtcttatttgccaagacaagat
ctggagggaaccccttactttgaatctggagtcagcctcttctctgatgaccctgagtct
gatctttctgtggacagagccccagaaccggttcatgttagcagcatgccaacttcaacc
tctgccttgaaattaccccaatttcaagttgaagaatcagccaagagtacagctgctgtt
catattactaatactgctgggtataataagagggaagacattgagggcaaggagaagcca
gaaacgatgtcttcaacaaaaagagtcaacaaaagaatatctatggtggcatcaggcttg
actccaaaagaattggtgcttgtgcagaagtttgccagaagacaccaaatcaccttaact
aatgtaatttctgaagagactactcatgtcattatgaaaacagatgctgagtttgtgtgt
gaacggacactgaaatattttctgggtattgcaggaggaaaatgggtagttagctatttc
tgggtgacccagtccattaaagaaagaaagatgctagatgagcatgattttgaagtcaga
ggagatgttgtcaatggaagaaaccaccagggtccgaagcgagcaagagaatctcgggac
agaaagatcttcgggggcctagaaatctgttgctatgggcccttttccaacatggccaca
gatcaactagagtggatggtgcgcctctgtggggcttctgtggtgaagaggccttcgtta
ttcactctcagcaaggctactcacccaattgtggtcgtgcaaccggatgcctggacagag
gacagtggcttccatgcgattgggcagatgtgtgaggcacctgtggtgacccgagagtgg
gtattggacagtgtagccctctaccagtgccaggagctggacacctacctgatcccccag
attcccagagctactgctgacctcagccagccatgtgtgtag
DBGET
integrated database retrieval system
