Leopardus geoffroyi (Geoffroy's cat): 123604168
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Entry
123604168 CDS
T10761
Symbol
FASN
Name
(RefSeq) fatty acid synthase isoform X1
KO
K00665
fatty acid synthase, animal type [EC:
2.3.1.85
]
Organism
lgf Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf00061
Fatty acid biosynthesis
lgf01100
Metabolic pathways
lgf01212
Fatty acid metabolism
lgf04152
AMPK signaling pathway
lgf04910
Insulin signaling pathway
lgf04936
Alcoholic liver disease
Module
lgf_M00082
Fatty acid biosynthesis, initiation
lgf_M00083
Fatty acid biosynthesis, elongation
Brite
KEGG Orthology (KO) [BR:
lgf00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
123604168 (FASN)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
123604168 (FASN)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
123604168 (FASN)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
123604168 (FASN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
lgf01004
]
123604168 (FASN)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
lgf04147
]
123604168 (FASN)
Enzymes [BR:
lgf01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.85 fatty-acid synthase system
123604168 (FASN)
Lipid biosynthesis proteins [BR:
lgf01004
]
Fatty acid synthase
Animal type
123604168 (FASN)
Exosome [BR:
lgf04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
123604168 (FASN)
Exosomal proteins of breast milk
123604168 (FASN)
Exosomal proteins of colorectal cancer cells
123604168 (FASN)
Exosomal proteins of bladder cancer cells
123604168 (FASN)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Acyl_transf_1
ketoacyl-synt
Thioesterase
KR
Ketoacyl-synt_C
KAsynt_C_assoc
FAS_pseudo-KR
ADH_zinc_N_2
ADH_zinc_N
PKS_DH_N
PP-binding
Methyltransf_12
adh_short
PS-DH
Methyltransf_23
Methyltransf_11
Thiolase_N
Methyltransf_31
DUF7080
Methyltransf_25
AlaDh_PNT_C
Motif
Other DBs
NCBI-GeneID:
123604168
NCBI-ProteinID:
XP_045345899
LinkDB
All DBs
Position
E1:complement(60591456..60609768)
Genome browser
AA seq
2545 aa
AA seq
DB search
MEDVVIAGMSGKLPESENMEEFWANLIGGVDMVTDDDRRWKAGLYGLPKRTGKLKDLSKF
DASFFGVHPKQAHTMDPQLRLLLEVTYEAILDGGINPATLRGTHTGVWVGVSGSEASEAL
SRDPETLLGYSMVGCQRAMMANRLSFFFDFKGPSIALDTACSSSLLALQNAYQAIRRGEC
PAAIVGGLNILLKPNTSVQFMKLGMLSPDGTCKAFDESGDGYCRAEAVVAVLLTKKSLAR
RVYATILNAGTNTDGCKEQGVTFPSGEAQEQLIRSLYEPAGLSPESLEYIEAHGTGTKVG
DPQELNGITRALCPSRQEPLLIGSTKSNMGHPEPASGLVSLAKVLLSLEHGLWAPNLHFR
SPNTKIPALQDGRLQVVQRPLPVRGGNVCINSFGFGGSNVHVILQPNLRPPLAPTRHTSL
PRLLRASGRTPEAVHCLLEQGRRHSQDLAFVSMLNDIAAISPTAMPFRGYTVLGGKGGSQ
EVQQVAAGERPLWFICSGMGAQWCGMGLSLMRLDSFRDSILRSDEAVKPLGLQVSELLLS
TDEATFDDIVHAFVSLTAIQIALIDLLNSMGLRPDGIIGHSLGEMACGYADGCLSQEEAI
LAAYWRGQCIKEANIPLGTMAAVGLSWEECKQRCPPGVVPACHNSEDTVTISGPQAEVAA
FVAELKQEGVFAKEVRTGGMAFHSYFMDSIAPTLLQALKKVIREPRPRSARWLSTSIPEA
QWQGSLARTFSAEYNVNNLVSPVLFQEALWHVPRDAVVLEIAPHALLQAVLKRGLKPSCT
IVPLMKKDQRDNLEFFLSNVGKLHLLGFDVNPNGLLPPVEFPVPRGTPLISPHIKWDHSQ
TWDVPTAKDFPSGSSGSSASTVCNISISPESPDHYLVDHCIDGRVLFPATGYLCLVWKSL
ARTLSQNMEQVPVVFEDVTLHQATVLPKTGTVPLEVRLLQASRTFEVSENGNLIVSGKVY
QWEDPDTKLFDSRDGLDTTDPTATFHLSQRDVYKELRLRGYDYGPHFQGILEANLEGNAG
RLLWKNNWVTFLDAMLQTSILGLAQCGLRLPTRITSVRIDPATHQRRVYSQGEAQAVNVL
VNSCLNSTVAGGVLISGLHASMAPRRQQEQFAPILEKFCFTPHTEEGLLAGDAALQEGLQ
LCRGLAQALQTKVAQQGLKMVVSGLDGAQAPQEPPKQGLPRLLAAACQLQLNGGLQLELG
QLLAQQRPLLQDDPLLSGLLASPALKACVDTAVENMPSLKMKVVEVLAGDGHLYSHIPAL
LNTQPMLQLEYTATDRHPQALEAVQAKLQQHGIAQGQWDPAGPAPGSLGSADLLLCNCAV
ASLGDPATAVGNMGAALKEGGFLLLHALLKGHPLGETVAFLTCPEPRRGQQSLLSQDEWE
SLFAAASLHLVALKKSFYGSVLFLCRRPVPQDSPVFLPVEDPSFQWVNSLKDILADSSHQ
PVWLTANSCPDSGVVGLVNCLRREPGGHRIRCILVSNLSSTSRTPSLDPGSSELQKVLRG
DLVMNVYRDGAWGAFRHFPLERGLPEEQTEHAFVNVLTRGDLSSIRWVCSPLRHTQLTGP
GAQLCAVHYASLNFRDIMLATGKLSPDAIPGKWALHSCLLGMEFSGRDASGKRVMGLVPA
EGLATSVLLSQDFLWEVPSSWTLEEAASVPVVYTTAYYSLVVRGRVHPGETVLIHSGSGG
VGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDDTSFANSRDTSFEQHVLRHTAGK
GVDLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHLLGMAVFLKNVTFHGVLLDSL
MDEGGNSWQEVAALLKAGIRDGVVQPLKCTVFPKDRVEDAFRYMAQGKHIGKVVIQVRRG
PGCPGSPRSLRSSPRGSARARPLLRMQVRREEPEAVLRETGPTLMAAVSRTYCPAHKSYV
ITGGLGGFGLELAQWLVLRGARKLVLTSRSGIRTGYQAKQVREWRRQGIQVLVSTSNASS
LDGAQSLIDEATQLGPVGGVFNLAVVLRDAMLENQTPELFQDVNRPKYSGTVNLDRVTRA
ACPELDYFVAFSSVSCGRGNAGQTNYGFANSTMERVCEKRQHDGLPGLAIQWGAIGDVGI
VLESMGSNDTVIGGTLPQRIASCLEVLDLFLNQPHPVLSSFVLAEKKATAHDDSSGSQDP
MEAVAHILGIRDLATVNLDSSLADLGLDSLMGVEVRQMLEREHDLVMSMRDIRQLTLRKL
QELSSKAGTANELAAPTPKEDTPAGQQAQLNLSTLLVNPEGPTLTRLNSVQSSERPLFLV
HPIEGSIAVFRSLASKLSIPTYGLQCTRAAPLDSIQSLAAYYIECIRQVQPEGPYRIAGY
SYGACVAFEMCSQLQAAQQGPTPAHNSLFLFDGSHAYVLAYTQSYRAKLTPGCEAEAEAE
AMCFFVQQFTDMEHNRVLEALLPLKGLEERVAATVDLITRSHAGLDPRELSFAARSFYHK
LRAAEQYIPRATYHGNVTLLRAKTGSVYGEGLGADYNLSQVCDGKVSVHVIEGDHRTLLE
GSGLETILSIIHSSLAEPRVSVREG
NT seq
7638 nt
NT seq
+upstream
nt +downstream
nt
atggaggacgttgtgattgctggcatgtccgggaagctgcccgagtccgagaacatggag
gagttctgggccaacctcatcggcggcgtggacatggtgacagacgatgacaggaggtgg
aaggcaggactctacggcctgcccaagcgtaccggcaagctaaaggacctgtccaagttc
gatgcctccttcttcggggtccacccaaagcaggctcacacgatggacccccagctgcgc
ttgctactggaggtcacctacgaggccatcctggatggaggcatcaacccggctaccctg
cgagggacacacacaggcgtctgggtgggcgtgagcggctcggaggcctcagaggctctg
agccgagaccccgagactctcctgggctacagcatggtgggctgccagcgggctatgatg
gccaaccgcctctccttcttctttgattttaaagggcccagcatcgctctggacacggcc
tgctcctccagcctgctggcccttcagaacgcctaccaggccatccgcaggggagagtgc
cccgcggccatcgtgggcggcctcaacatcctgctcaagcccaacacctccgtgcagttc
atgaagctcggcatgctgagccccgacggaacctgcaaggccttcgacgagtccggggac
ggctactgccgtgcggaggccgtggtggccgtcctgctgaccaagaagtccctggcccgg
cgtgtgtacgccaccatcctcaacgccggcaccaacacggacggctgcaaggagcaaggt
gtgaccttcccctccggggaggcccaagaacagctcatccgctcgctgtacgagccggct
gggttgagcccagagtccctcgagtatatcgaagcccacggcacagggaccaaggtgggg
gacccccaggagctgaacggcatcacccgagccctgtgtccctcccgccaggagcccctg
ctgatcgggtccaccaagtcgaacatggggcacccggagcccgcttcggggctcgtgtct
ctggccaaggtgctgctgtccctggagcatgggctctgggcccccaacctgcacttccgg
agcccgaacaccaagatccccgcgctccaggacggacggctgcaggtggtgcagcggccc
ctgcccgtccgcggaggcaacgtgtgtatcaattcgttcggcttcggcggctccaacgtg
cacgtcattctccagcccaatctgcggccgcccttggcacccacccggcacacctctctg
ccccgtctgctgcgggccagcggacgcaccccggaggccgtgcactgtctgctggagcaa
ggccgccggcacagccaggacctggccttcgtgagcatgctcaatgacatcgcggccatc
tcccccaccgccatgcccttccggggctacaccgtgctgggtggcaagggtggcagccag
gaggtacagcaggtggccgctggcgagcgtccactctggttcatctgctcggggatgggc
gcacagtggtgcgggatgggattgagcctcatgcgcctggacagcttccgcgactccatc
ctgcgctccgacgaggccgtgaagcccttgggactgcaggtgtctgagttgctgctgagc
acagacgaggccacctttgacgacatcgtccacgccttcgtgagcctcaccgccatccag
atcgccctcatagacctgctgaactccatgggtctgcggcccgacggaatcatcgggcac
tccctgggtgagatggcctgcggctacgcagatggctgcctgtctcaggaggaggccatc
ctcgccgcctactggaggggccagtgcatcaaggaggccaacatcccactggggaccatg
gcggccgtcggcttgtcctgggaggagtgtaagcagcgctgcccccctggtgtcgtgccc
gcctgccacaactctgaggacacagtgaccatctcgggaccgcaggccgaggtggctgcg
ttcgtggcggagctgaagcaggagggtgtgtttgccaaggaggtgcggacgggcggcatg
gccttccactcctacttcatggactccatcgcccccacgttgcttcaggccctcaagaag
gtgatccgggagccgcggccccgctcggcacgctggctcagtacctccatccccgaggcc
cagtggcagggcagcctggcccgcacgttctcggcggagtataacgtcaacaatttggtg
agccccgtgctgttccaggaggcgctgtggcacgtgcccagggacgccgtggtgttggag
atcgccccccatgccctgctgcaggccgtcctcaagagaggcctgaagcccagctgtacc
atcgtccctctgatgaagaaggaccaaagagacaatctggagttcttcctcagcaacgtg
ggcaagttgcacctgctgggcttcgatgtcaaccccaatggcctgcttccacccgtggag
ttcccggtgccccggggcacccctctcatctcccctcacatcaagtgggaccacagtcag
acctgggacgtccccaccgccaaggacttccccagcggctccagtggctcctctgcctcc
accgtctgcaacatcagcatcagccctgaatcccctgaccactacctggtggaccactgc
atcgacggccgcgtcctcttccccgccaccggctacctgtgcctggtctggaagagtctg
gcacggaccttgagtcaaaacatggaacaagtacccgtggtgtttgaggacgtgacgctg
caccaggctaccgtcctccccaagaccgggaccgtgcccctggaagtgcggctcctacag
gcttcccgtaccttcgaggtgtctgagaacggcaacctgatagtgagcgggaaggtttac
cagtgggaggaccccgacaccaagctgttcgacagccgggacggcctggacaccacggac
cccacagctacgttccacctgagccagagggacgtgtacaaagagttgaggctgcgtggc
tacgactatggccctcactttcaaggcatcctcgaggccaacctcgaaggcaacgcgggc
cggctgctgtggaagaacaactgggtgacgttcctggacgccatgctgcagacatccatc
ctgggcctggcccagtgcggcctgcgtctgcccacccgcatcacctctgtccgcatcgac
cccgccacccaccagcgcagggtgtactcgcagggcgaggcccaagcggtcaacgtgctg
gtgaacagttgtctgaacagcacggtggccggcggcgtcctcatctcgggcctccacgcc
tcgatggccccacggcggcagcaggagcagtttgcgcccatcctggagaagttctgcttc
acgccgcacacggaggaggggctcctggctggagacgcggccctgcaggaggggctgcag
ctgtgcagggggctggcacaggcgctgcagaccaaggtggcccagcaggggctgaagatg
gtggtgtctgggctggacggggcccaggccccccaggagcctccaaagcaaggcctgccc
cggctgctggcggccgcctgccagctgcagctcaacgggggcctccagctggagctgggc
cagctgctggcccaacagaggcccctgctgcaggacgaccccctgctcagcggcctcctc
gcttccccggcgctcaaggcctgcgtggacaccgccgtggagaacatgcccagcctcaag
atgaaggtcgtggaggtgctggctggcgatggccacctgtattctcacatcccagcgctg
ctcaacacccagcccatgctgcagctggagtacacggccactgaccgccaccctcaggcc
ctggaggccgtgcaggccaagctgcagcagcacggcatagcccagggccagtgggaccct
gcgggccccgcccctggcagcctgggctcggctgatctcctcctgtgtaactgtgccgtg
gccagcctcggtgacccggccacggccgttggcaacatgggggccgctctcaaggagggc
ggcttcctgctgctgcacgctctgctcaaaggacacccccttggagagacggtcgccttc
ctcacctgcccggagccgcggcgaggccagcagagccttctaagccaggacgagtgggag
agtctgtttgccgcggcgtccctgcacctggtggccctgaagaagtccttctatggctct
gtgctcttcctgtgccgtcggccggtcccacaggacagccctgtcttcctgcctgtggag
gaccccagtttccagtgggtgaactccctgaaggacattttggccgactcctcccatcag
cccgtgtggctaacagccaacagctgccccgactcaggcgtcgtgggcttggtgaactgt
ctccgcagagagcctggcgggcaccggattcggtgcatcctggtgtccaacctcagcagc
acgtcccgcaccccgagtttggaccccggctcctcggagctgcagaaggtgctacggggg
gacctcgtgatgaatgtctaccgagacggggcctggggggccttccgccatttccccctg
gagcgcggcctgccagaggagcagaccgagcacgccttcgtgaacgtcctcacgcggggg
gacctctcctccatccgctgggtctgctcccctctgcgtcacacccagctcaccggcccc
ggcgcccagctctgtgccgtccactatgcctccctcaacttcagagatatcatgctggcc
acgggcaagctgtcccctgacgccatcccagggaagtgggccctccacagctgtttgctg
ggcatggagttctctggccgagatgccagcggcaagcgcgtcatggggctggtgcccgcc
gaaggcctggctacctccgtcctgctctctcaggacttcctgtgggaggtgccctccagc
tggacccttgaggaggcggcttcggtgcctgtggtctacacaactgcctactactcgctg
gtggtgcgggggcgcgtgcaccctggggagacggtgctcatccactcaggctcgggcggc
gtgggccaggccgccatcgccatcgccctcagcctgggctgccgcgtcttcactaccgtg
gggtcggccgagaagcgggcgtacctccaggctaggttcccccagctcgacgacaccagc
ttcgccaactcccgggacacgtcctttgaacagcacgtgctgcggcacacggcagggaag
ggtgtggacctggtgctgaattctctggcggaagaaaagctacaggccagcgtgcggtgc
ctggcccagcacggccggttcctggaaattggcaaattcgacctttcgaacaaccacctg
ctgggcatggccgtcttcctgaagaacgtgaccttccacggggttctgctggactcgctc
atggatgaaggtgggaacagctggcaggaggtggctgcgctgctgaaggcgggcatccgg
gacggtgtggtgcagcccctcaagtgcaccgtgttccccaaggaccgggtggaggacgcc
ttccgctacatggcccaagggaaacacatcggcaaagtggtcatccaggtgaggaggggg
cccggctgccccggctccccccgctccctccgctccagccccaggggcagcgctcgagca
cggccgctgctccgaatgcaggtgcgcagggaggagccggaggcggtgctgcgggagacg
ggtcccaccctgatggccgccgtgtccaggacctactgcccggcccataagagctatgtc
atcaccgggggcctgggcggcttcggcctggagctggcccagtggcttgtgctgcgaggg
gcccggaaactcgtgctgacctctcgttctgggatccgcacaggctaccaggccaagcag
gtccgtgagtggaggcgccagggcatacaggtcctggtgtccaccagcaacgccagctcg
ctggatggggcccagagcctcattgatgaggccacgcagctggggcccgtgggaggcgtc
tttaacctggccgtggtcctgagagacgccatgctggagaaccaaacccctgagctcttt
caggacgtcaacaggcccaagtacagcggcaccgtgaacctggacagggtgacccgagct
gcgtgccccgagctggactactttgtggccttctcctccgtgagctgcgggcgcggcaac
gccggccagaccaactatggcttcgccaactccaccatggagcgcgtgtgtgagaagcgc
cagcacgacggcctcccgggcctcgccattcagtggggcgccatcggtgacgtgggcatt
gtcctggagtccatgggctccaacgatacggtcatcggcgggacgctgccgcagcggatt
gcctcctgcttggaggtgctggacctcttcctgaaccagccccaccccgtcctgagcagc
tttgtgctggccgagaagaaggccactgcccacgatgacagcagtggctcgcaggacccg
atggaggccgtggcccacatcctgggcatccgagacttggccaccgtcaacctggacagc
tcactggcagacctgggcctggactcgctcatgggcgtggaggtgcgccagatgttggag
cgcgagcatgacctggtgatgtccatgcgggacatccggcagctcacgctccggaagttg
caggagctttcctcgaaggctggcacagctaatgagctggcagcccccacacccaaggag
gacacccctgccggccagcaggcccagctgaacctcagcaccctgctggtgaaccccgag
ggcccgaccttgacacggctcaactcggtgcagagctctgagcgccccttgttcctggtg
caccccatcgagggctccatcgctgtgttccgcagcctggcgtccaagctcagcatcccc
acctacggcctacagtgcactcgagctgcgcccctggacagcatccagagtctggccgcc
tactacatcgagtgcatcaggcaggtgcagccggaggggccctaccgcatcgccggctat
tcctacggggcctgcgtggccttcgagatgtgctcgcagctgcaggccgcgcagcagggc
cccacccccgcgcacaacagcctcttcttgttcgacggttcgcacgcctatgtgctggcc
tacacacagagctaccgcgcgaagctgacccctggctgtgaggccgaggccgaggccgag
gccatgtgcttcttcgtgcagcagttcaccgacatggaacacaacagggtgctggaggcg
ctgctgcccctcaagggcctggaggagcgcgtggcggccaccgtagacctgatcacgcgc
agccacgcgggcctggacccccgcgagctgagcttcgcggcacgctccttctaccacaag
ctgcgcgcagccgagcagtacatcccccgggccacctaccacggcaacgtgacgctgctg
cgcgccaagacgggcagcgtgtacggcgagggcctgggcgccgactacaacctgtcccag
gtgtgcgacggcaaggtgtccgtgcacgtgatcgagggggaccaccgcacgctgctggag
ggcagcggcctggagactatcctcagcatcatccacagctccctggccgagccgcgcgtc
agcgtccgggagggctaa
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integrated database retrieval system
