Leopardus geoffroyi (Geoffroy's cat): 123607347 Help Entry 123607347         CDS       T10761                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism lgf  Leopardus geoffroyi (Geoffroy's cat) Pathway lgf04010   MAPK signaling pathway lgf04014   Ras signaling pathway lgf04015   Rap1 signaling pathway lgf04022   cGMP-PKG signaling pathway lgf04066   HIF-1 signaling pathway lgf04068   FoxO signaling pathway lgf04072   Phospholipase D signaling pathway lgf04081   Hormone signaling lgf04150   mTOR signaling pathway lgf04151   PI3K-Akt signaling pathway lgf04152   AMPK signaling pathway lgf04211   Longevity regulating pathway lgf04213   Longevity regulating pathway - multiple species lgf04520   Adherens junction lgf04910   Insulin signaling pathway lgf04913   Ovarian steroidogenesis lgf04923   Regulation of lipolysis in adipocytes lgf04930   Type II diabetes mellitus lgf04931   Insulin resistance lgf04932   Non-alcoholic fatty liver disease lgf04960   Aldosterone-regulated sodium reabsorption lgf05010   Alzheimer disease lgf05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:lgf00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     123607347 (INSR)    04014 Ras signaling pathway     123607347 (INSR)    04015 Rap1 signaling pathway     123607347 (INSR)    04066 HIF-1 signaling pathway     123607347 (INSR)    04068 FoxO signaling pathway     123607347 (INSR)    04072 Phospholipase D signaling pathway     123607347 (INSR)    04022 cGMP-PKG signaling pathway     123607347 (INSR)    04151 PI3K-Akt signaling pathway     123607347 (INSR)    04152 AMPK signaling pathway     123607347 (INSR)    04150 mTOR signaling pathway     123607347 (INSR)   09133 Signaling molecules and interaction    04081 Hormone signaling     123607347 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     123607347 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     123607347 (INSR)    04923 Regulation of lipolysis in adipocytes     123607347 (INSR)    04913 Ovarian steroidogenesis     123607347 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     123607347 (INSR)   09149 Aging    04211 Longevity regulating pathway     123607347 (INSR)    04213 Longevity regulating pathway - multiple species     123607347 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     123607347 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     123607347 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     123607347 (INSR)    04932 Non-alcoholic fatty liver disease     123607347 (INSR)    04931 Insulin resistance     123607347 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:lgf01001]     123607347 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:lgf04090]     123607347 (INSR) Enzymes [BR:lgf01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      123607347 (INSR) Protein kinases [BR:lgf01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    123607347 (INSR) CD molecules [BR:lgf04090]  Proteins   123607347 (INSR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Ig_DSCAM-DSCAML_C Kinase-like B2 Motif Other DBs NCBI-GeneID:  123607347 NCBI-ProteinID:  XP_045352455 LinkDB All DBs Position A2:6404921..6546017 Genome browser AA seq 1381 aa AA seqDB search MGAGAGRGAATAPLLVAVAALLLGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL QILLMFKTRPEDFRDLSFPKLVMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTADGLCCHSECL GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCRDLHNKCKNSRRQG CHQYVIHNNRCIPECPSGYTMNSSNLMCTPCLGPCPKVCHILEGEKTIDSVTSAQELRGC TVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL EIGNYSFYALDNQNLRQLWDWSKHNLTISQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE RQAEDSELYELDYCLKGLKLPSRTWSPPFESEGSQKHNQSEYEESAGECCSCPKTDSQIL KELEESSFRKTFEDYLHNVVFVPRKSFSSPGAEDSRPSRKRRALADAGNVTAAVPTVPGF PNTSSSVPTSPEEHKPFEKVVNKESLVISGLRHFTGYRIELQACNQDAPEERCSVAAYVS ARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVS RRHFALERGCRLRGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIGP LIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPRE KITLLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKGF TCHHVVRLLGVVSKGQPTLVVMELMVHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAA EIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVR WMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNC PERVTDLMHMCWQFNPKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEMEF EDMESVPLDRASHSQREEAGGRDGVSSLGLKRNYEDHIPYTHMNGGKKNGRILTLPRSNP S NT seq 4146 nt NT seq  +upstreamnt  +downstreamnt atgggcgccggggctgggcggggggcggccaccgcgccgctgctggtggcggtggccgcg ctgctgctgggcgccgcgggccacctgtaccccggagaggtctgccctggcatggatatc cggaacaacctgacgaggctgcacgaactggccaactgctcggtcattgaaggtcatttg cagatactgctcatgttcaaaacgaggcccgaggacttccgagacctcagtttccccaaa ctcgtcatgatcactgattacctgctgctcttccgggtgtatgggctggagagcctgaag gacctcttccccaatctcacggtcatccggggctcacgcctcttcttcaactacgcgctg gtcatcttcgagatggttcacctgaaggagcttggcctctacagcttgatgaacattacc cggggctccgtccgcatcgagaagaacaatgagctgtgctacctggccaccatcgactgg tcgcgcatcctggattcggtggaggataattacattgtgttgaacaaagacgacaacgag gagtgtggggacatttgtccaggcactgcaaagggcaagaccaactgccctgccactgtc atcaacgggcagtttgtggagcgttgttggacacacagccattgccagaaagtttgtccg accatctgcaagtcgcacggctgcacggccgacggcctctgctgccacagcgagtgtttg ggcaactgctccgagcccgacgaccccaccaagtgcgtggcctgtcgcaacttctacctg gacggcaggtgcgtggagacctgcccgcccccctactaccacttccaagactggcgctgc gtgaacttcagcttctgccgggacctgcacaataaatgcaagaactcccggagacagggt tgccaccagtatgtcattcacaacaacaggtgcatccctgagtgcccctcggggtacacg atgaattccagcaacctgatgtgtactccctgcctgggcccctgtcccaaggtctgccac atcctggaaggcgagaagaccatcgactcggtgacatctgcccaggagctccgaggctgc accgtcgtcaacggaagcctaatcatcaacattcgagggggcaacaacctggcagctgag ctggaggccaacctcggactcattgaagaaatttctgggtatctgaagatccgaagatcc tatgctcttgtgtcactttcctttttccggaagttacggctgattcggggagagaccttg gaaatcgggaactactctttctatgccttggacaatcagaacctgaggcagctatgggac tggagcaaacacaacctcaccatctctcaggggaaactcttcttccactataatcccaaa ctctgcttgtcggaaattcacaagatggaggaggtttcaggaaccaaggggcgccaggag cggaacgacattgccctgaagaccaatggggaccaggcgtcttgtgaaaatgaactactt aaattttcttacattcggacatcttacgacaagatcttgctgaaatgggagccgtactgg ccccctgacttccgagacctcctgggcttcatgctcttctacaaagaggccccttatcag aatgtgaccgagttcgacgggcaggacgcgtgtggctccaacagctggacggtggtggac attgacccgcctctgaggtccaatgaccccaagtcgcagaaccacccagggtggctgatg cggggtctcaagccctggacccagtatgccatctttgtcaagaccttggtcaccttttct gatgagcgccgcacgtatggggccaagagtgacatcatctatgtccagaccgatgccacc aacccttccgtccccctggatcctatctcggtgtcgaattcctcctctcagatcattctg aagtggaagcctccctcggaccccaatggcaacatcacgcactacctggtgttctgggag aggcaggcggaggacagcgagctgtatgagttggattattgcctcaaagggttgaagctg ccttcccggacctggtccccgccgttcgagtccgagggctcccagaagcacaatcagagt gaatacgaggagtccgctggcgaatgctgctcgtgtcccaaaaccgactctcagatcctg aaggagctggaggagtcctctttcaggaagacgtttgaggattacctgcacaatgtggtt ttcgtgcccagaaaatccttttcaagccctggtgctgaggacagtaggccgtcgcggaag cgcagggccctcgccgacgctgggaacgtgacggccgccgtgcccacggtgcctggtttc cccaacacttccagcagcgtgcccacgagcccggaagagcacaagcccttcgagaaggtg gtgaacaaagagtcgctggtcatctccggcctgcgtcacttcaccggctaccgcatcgag ctgcaggcttgcaaccaagatgcccccgaggagaggtgcagcgtggccgcctacgtcagc gccaggaccatgcccgaagccaaagcagacgacattgttggccctgtgacccatgaaatc ttcgagaacaatgtggttcacttgatgtggcaagagcctaaagaacccaacggattgatc gtgctgtatgaagtgagttaccgacggtatggtgatgaggagctgcacctctgtgtctcc cgtagacactttgctctggagcggggctgcaggctgcgagggctgccgccggggaattac agtgtgcgagttcgggccacctccctggcgggcaacggctcctggacagaagccacttat ttctacgtgacagactatttagatgtcccatcgaacattgcaaaaattatcatcgggcct ctcatctttgtctttctcttcagtgttgtgattggaagtatttatctattcctgagaaag aggcagccggatgggccactggggccgctgtatgcttcttcaaaccctgagtacctcagt gccagtgatgtgtttccctgctctgtgtatgtgccggacgagtgggaggtgcctcgggag aagatcactctcctgcgcgagctggggcagggctccttcggcatggtgtacgagggcaat gccagggacatcgtcaagggcgaggcggagacccgtgtggcggtgaagacggtcaacgag tccgccagtctgcgagagaggatcgagtttctcaacgaggcctcagtcatgaagggcttc acctgtcatcacgtggtccgcctcctgggggtggtgtccaaaggccagccgacgctggtg gtgatggagctgatggttcacggagacctgaagagctacctccgctccctgcggccggag gctgagaataaccctggccgccctccccctactctgcaagagatgattcagatggcggcg gagatcgccgacgggatggcgtacctgaatgccaagaagtttgtgcatcgggatctcgca gctcgaaactgcatggtggcccacgacttcaccgtcaaaattggagacttcggaatgacc agagacatctatgaaacggattactaccggaaaggaggcaagggtctgctccccgtgcgg tggatggcaccggaatccctgaaggacggggtcttcaccacttcttctgacatgtggtcc tttggtgtggtcctttgggaaatcaccagcttggcggaacaaccttaccaaggcctgtct aatgaacaggtgttgaaatttgtcatggacggaggatatttggaccaacctgacaactgt ccggagagagtcaccgacctgatgcatatgtgctggcagttcaatcccaagatgcggccc accttcctggagatcgttgacctgctcaaggacgacctgcaccccagctttccggaagtt tccttcttccacagcgaggagaacaaggcgcctgagagtgaggagttggaaatggagttt gaggacatggagagtgtccccctggatcgggcctcacactcacagagggaagaggccggg ggccgggatggagtgtcctcgctgggcctcaagcggaactacgaggaccacatcccctac acccacatgaacgggggcaagaaaaacggacggattctgaccctgccgaggtcgaatcct tcctaa

DBGET integrated database retrieval system