KEGG   Lacticaseibacillus huelsenbergensis: LHUE1_002100
Entry
LHUE1_002100      CDS       T09416                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
lhn  Lacticaseibacillus huelsenbergensis
Pathway
lhn03030  DNA replication
lhn03410  Base excision repair
lhn03420  Nucleotide excision repair
lhn03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:lhn00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    LHUE1_002100 (ligA)
   03410 Base excision repair
    LHUE1_002100 (ligA)
   03420 Nucleotide excision repair
    LHUE1_002100 (ligA)
   03430 Mismatch repair
    LHUE1_002100 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:lhn03032]
    LHUE1_002100 (ligA)
   03400 DNA repair and recombination proteins [BR:lhn03400]
    LHUE1_002100 (ligA)
Enzymes [BR:lhn01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     LHUE1_002100 (ligA)
DNA replication proteins [BR:lhn03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     LHUE1_002100 (ligA)
DNA repair and recombination proteins [BR:lhn03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     LHUE1_002100 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     LHUE1_002100 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     LHUE1_002100 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      LHUE1_002100 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 DNA_ligase_ZBD PTCB-BRCT Nlig-Ia HHH_8 HHH Zn_ribbon_NUD
Other DBs
NCBI-ProteinID: WFB38566
LinkDB
Position
2271727..2273751
AA seq 674 aa
MLTKPAAQFTLEEAEAEVAKLRKQLNQWRLEYYTKDAPTVTDNVYDDHYRDLQALEAAFP
KLVTPDSPTQQVGDVINSDFAKVQHPIPMLSMGDVFSFEELSEWDARMQANVGHPVNYNV
ELKIDGLALSLIYEDGKLVQGSTRGDGNIGEDVTKNVLTIDSVPKTLKKPLSLEVRGECY
MPKAAFAKLNARQETEGNPPFANPRNAAAGSLRQLNPRVTAGRELDTFIYTLIDPDRFNV
KTQHEAIAFMHDLGFTTNPSSEVASDMQAIDAYITKYTSDRDALPYGIDGIVLKVNDLAL
QAQLGNTVKVPRWEIAYKFPPEEAETVIHEIVWTVGRTGVVTPTAVMDPVQLAGTTVSRA
TLHNADMIHDKDIRIGDTVMLHKAGDIIPEVSRVLVAKRPANTPPTPIPEKCPSCGQRLV
HLDDEVALRCINPMCPAQMQEQLTHFASRNAMNIDGLGPKIIAQLQAKHLVRDVADLYRL
TATDLAQLDKFKEKSINNLLSAIHNSRQNSVERLIFGLGIRHVGGKAARILAEHFGDLDH
LMAASQEDIAEIPNIGPTIAEAVVTYFKTDTVRKLIDQLRSAGVNLRYTGPTQSAVKDSF
VSGKTVVITGKFAEFSRPDLTKQLEKLGAKVTGSVSKKTDLVIVGEAAGSKLTKAQKLNV
PTMDETELLANLKN
NT seq 2025 nt   +upstreamnt  +downstreamnt
gtgttaacaaaaccagctgctcaatttacgcttgaagaagccgaggcggaagtcgccaag
ctgcgcaagcaattaaatcaatggcgtctggagtattacaccaaagacgcaccgaccgta
acggataacgtttatgatgatcattatcgtgacttgcaggcgttagaagcggcatttcct
aaattggtcacccctgattcgccgacgcaacaggttggcgatgtgatcaactcggacttt
gccaaagttcagcatccgatccctatgttgtcgatgggcgatgtcttttcatttgaagaa
cttagcgaatgggatgcgcgcatgcaggctaatgttgggcatccggttaattacaatgtg
gagttaaaaattgacggacttgccttatcgcttatttatgaagatggcaaattggtccaa
ggctcgacgcgcggcgatggtaacattggcgaagacgtcaccaagaatgtgttgaccatt
gattcggtaccgaaaaccttgaagaagccgttgtcactcgaagtgcgcggtgaatgctat
atgcctaaagcggcgtttgctaaattgaatgcccgacaggaaactgaaggcaatccgcca
ttcgccaatccgcgtaatgcggccgcgggctccttgcgtcagctgaatccgcgcgtcacg
gccggtcgggaactggacacgtttatttacacgttgattgatcctgatcggtttaacgtg
aaaacgcaacatgaagcgattgcgttcatgcatgatttgggctttaccaccaatcccagt
tcagaagttgccagtgatatgcaggcgattgatgcgtacattactaagtacacaagtgat
cgcgatgcgttgccgtatggaattgatgggatcgttttaaaagtcaatgatttggcgctg
caagcccagttaggtaacacggttaaagtgccgcggtgggaaattgcctataagtttccg
cctgaagaagccgagacagtgatccatgaaattgtctggacagtggggcgaaccggggtt
gtcacgccgaccgcggtgatggatccggttcagctggcggggacgacggtttcgcgggca
accctgcacaatgcggacatgattcatgataaagatatccgaattggcgatacggtcatg
ctgcataaagcaggcgacattatcccggaagtttcgcgggtgctggttgccaagcgcccg
gcgaatacgccaccgacaccgattccggaaaaatgtccgtcgtgcggtcagagactagtg
cacctcgatgatgaggtggcgttgcggtgcattaatccgatgtgtccggcacaaatgcag
gagcagctgacgcattttgcttcgcgtaacgccatgaacattgacgggttgggtcctaaa
atcattgcgcagctgcaggccaaacacctggtgcgggatgtcgccgatctctaccgcctg
actgcaaccgatctggctcagctggacaaattcaaagaaaaatcaattaataatttatta
agtgcgattcataacagtcggcaaaattccgtggaacgcctaatctttggattggggatt
cgtcacgttggcgggaaagccgcgcgaattcttgcggaacattttggcgacttggatcac
ctgatggctgccagtcaggaagacattgcggagattcctaatattgggccgactattgcc
gaagccgttgtgacctatttcaagactgatacggtacgaaagctgatcgatcaattgcgt
tctgcaggggtcaacctacgttataccggtccgacgcagtccgcggtaaaagatagcttt
gtttccgggaaaaccgtggtcatcacaggtaaatttgccgagttttcccgcccggatctg
acgaaacagcttgaaaaattaggcgccaaagttaccggatcggtttcaaagaaaacggat
ttggtgattgtcggtgaagcagctggcagtaagctgacgaaagcccagaaattaaatgtt
ccgacgatggatgaaacagaattgttggcgaacttgaagaattga

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