Lutra lutra (Eurasian river otter): 125094998 Help Entry 125094998         CDS       T08100                                  Name (RefSeq) caspase-8-like isoform X1   KO K04398   caspase 8 [EC:3.4.22.61] Organism llv  Lutra lutra (Eurasian river otter) Pathway llv01524   Platinum drug resistance llv04115   p53 signaling pathway llv04210   Apoptosis llv04215   Apoptosis - multiple species llv04217   Necroptosis llv04620   Toll-like receptor signaling pathway llv04621   NOD-like receptor signaling pathway llv04622   RIG-I-like receptor signaling pathway llv04623   Cytosolic DNA-sensing pathway llv04625   C-type lectin receptor signaling pathway llv04657   IL-17 signaling pathway llv04668   TNF signaling pathway llv04932   Non-alcoholic fatty liver disease llv04936   Alcoholic liver disease llv05010   Alzheimer disease llv05016   Huntington disease llv05022   Pathways of neurodegeneration - multiple diseases llv05132   Salmonella infection llv05134   Legionellosis llv05142   Chagas disease llv05145   Toxoplasmosis llv05152   Tuberculosis llv05160   Hepatitis C llv05161   Hepatitis B llv05162   Measles llv05163   Human cytomegalovirus infection llv05164   Influenza A llv05165   Human papillomavirus infection llv05167   Kaposi sarcoma-associated herpesvirus infection llv05168   Herpes simplex virus 1 infection llv05169   Epstein-Barr virus infection llv05170   Human immunodeficiency virus 1 infection llv05200   Pathways in cancer llv05203   Viral carcinogenesis llv05416   Viral myocarditis llv05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:llv00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     125094998  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     125094998    04215 Apoptosis - multiple species     125094998    04217 Necroptosis     125094998    04115 p53 signaling pathway     125094998  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     125094998    04621 NOD-like receptor signaling pathway     125094998    04622 RIG-I-like receptor signaling pathway     125094998    04623 Cytosolic DNA-sensing pathway     125094998    04625 C-type lectin receptor signaling pathway     125094998    04657 IL-17 signaling pathway     125094998  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     125094998    05203 Viral carcinogenesis     125094998   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     125094998    05161 Hepatitis B     125094998    05160 Hepatitis C     125094998    05164 Influenza A     125094998    05162 Measles     125094998    05168 Herpes simplex virus 1 infection     125094998    05163 Human cytomegalovirus infection     125094998    05167 Kaposi sarcoma-associated herpesvirus infection     125094998    05169 Epstein-Barr virus infection     125094998    05165 Human papillomavirus infection     125094998   09171 Infectious disease: bacterial    05132 Salmonella infection     125094998    05134 Legionellosis     125094998    05152 Tuberculosis     125094998   09174 Infectious disease: parasitic    05145 Toxoplasmosis     125094998    05142 Chagas disease     125094998   09164 Neurodegenerative disease    05010 Alzheimer disease     125094998    05016 Huntington disease     125094998    05022 Pathways of neurodegeneration - multiple diseases     125094998   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     125094998    05416 Viral myocarditis     125094998   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     125094998    04932 Non-alcoholic fatty liver disease     125094998   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     125094998  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:llv01002]     125094998 Enzymes [BR:llv01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      125094998 Peptidases and inhibitors [BR:llv01002]  Cysteine peptidases   Family C14: caspase family    125094998 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  125094998 NCBI-ProteinID:  XP_047576680 LinkDB All DBs Position 3:13292769..13317616 Genome browser AA seq 485 aa AA seqDB search MNFSKCLYNIGEQLDSDELASLKFLSMDYIPQKKQEPIKDPLMLFQRLQEKRLLEENNLS FLKELLFRINRLDLLVTYLDTSKQEMEQELRIPGRAQISAYRVMLFQISEDVSKLELKSF KFLLSQEISRCKLHDDLNLFDIFIEMEKRVILGERNLDTLKRICDQINRSLLKKITDYEE LSQEQTMIPQRSLDEISNDMSQLLVGEKSLRVPPMSDSPREQNCESETSEKVYQMESKPR GYCLIFNNYDFSIARKQVPKLHSIKDRNGTDLDADALCQTFSELHFEIVPFRDSTAKKIC DILKSYQSMDHTTRDCFICCILSHGDKGIIYGCDGQEVPIYELTSYFTGSKCPSLAGKPK IFFIQACQGDNYQKGIAVETDSEQNEACYESDSCQKSYIPDDADFLLGMATVNNCVSYRN PMEGTWYIQTLCQSLRERCPRGEDILTILTEVNFEVSNKDDRRNMGKQMPQPTFTLRKKL IFPCD NT seq 1458 nt NT seq  +upstreamnt  +downstreamnt atgaattttagtaaatgcctctataatattggagaacagctggacagtgacgagctggcc tccctcaaattcctgagcatggactacatcccccagaagaagcaggagcccatcaaggat cccctgatgttattccagagactccaggaaaagagactgttggaggaaaacaacctgtcc ttcttaaaggagttgctttttcggatcaacagactggacctgctagtcacctacctggac accagcaagcaggagatggagcaagagcttcggatcccgggcagagcccagatctctgct tacagggtcatgctttttcagatttcagaagatgtaagcaaattggaattgaagtccttt aagtttcttttgagccaggagatctctagatgtaaactgcacgatgatttgaacttgttt gatattttcatagagatggagaagagggtcatcctcggggaaagaaatttggacaccctg aaaagaatctgtgaccaaataaacaggagcctgctgaagaaaatcacggattatgaagaa ttaagccaagagcaaacaatgatccctcaaagaagtctagatgaaatttcaaatgatatg tctcagttgcttgtaggggagaaatccctgagggtaccgccaatgtcggactctccaaga gaacagaactgtgaatcagagacatcggaaaaagtttaccaaatggaaagcaaacctcga ggatattgtttgatctttaacaattatgactttagcatagcacggaagcaagtgcccaaa cttcacagcattaaggataggaatggaacagacttggatgcagatgctttgtgtcagacc tttagtgagcttcattttgagattgtgcctttcagagactctacagctaagaaaatctgt gacattctcaaatcctaccaaagcatggaccacactaccagggactgcttcatctgctgc atcctctcccatggagacaagggcatcatctatggctgtgatggacaggaagtccccatc tatgagttgacctcttacttcactggttctaagtgcccttcccttgcaggcaagcccaaa atcttttttattcaggcttgtcaaggggataactaccagaaagggatagctgttgagacc gactccgaacagaatgaagcctgttatgaatcggactcctgtcagaagagctatatccca gacgatgctgactttctgctggggatggccactgtgaataattgtgtttcctaccgaaac cccatggagggaacatggtatatccagacgctttgccagagcctgagagaaagatgtcct aggggagaagatattctcaccatccttactgaagtgaattttgaagtgagcaataaggat gacaggagaaacatgggcaaacaaatgccacaaccgaccttcacactgaggaaaaaactc attttcccttgtgactga

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