Lutra lutra (Eurasian river otter): 125096245
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Entry
125096245 CDS
T08100
Name
(RefSeq) vascular endothelial growth factor receptor 1 isoform X1
KO
K05096
FMS-like tyrosine kinase 1 [EC:
2.7.10.1
]
Organism
llv
Lutra lutra (Eurasian river otter)
Pathway
llv04010
MAPK signaling pathway
llv04014
Ras signaling pathway
llv04015
Rap1 signaling pathway
llv04020
Calcium signaling pathway
llv04066
HIF-1 signaling pathway
llv04151
PI3K-Akt signaling pathway
llv04510
Focal adhesion
llv04518
Integrin signaling
llv05202
Transcriptional misregulation in cancer
llv05323
Rheumatoid arthritis
Brite
KEGG Orthology (KO) [BR:
llv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
125096245
04014 Ras signaling pathway
125096245
04015 Rap1 signaling pathway
125096245
04066 HIF-1 signaling pathway
125096245
04020 Calcium signaling pathway
125096245
04151 PI3K-Akt signaling pathway
125096245
09133 Signaling molecules and interaction
04518 Integrin signaling
125096245
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
125096245
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
125096245
09163 Immune disease
05323 Rheumatoid arthritis
125096245
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
llv01001
]
125096245
Enzymes [BR:
llv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
125096245
Protein kinases [BR:
llv01001
]
Receptor tyrosine kinases (RTK)
VEGFR family [OT]
125096245
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Ig_3
I-set
Pkinase
ig
VEGFR-1-like_Ig-like
Ig_2
Ig_VEGFR-1-like_5th
V-set
VEGFR-2_TMD
VEGFR1-3_N_Ig-like
Ig_PDGFR_d4
Ig_4
C1-set
Ig_5
Herpes_gE
Haspin_kinase
HopBF1_kinase
ABC1
Motif
Other DBs
NCBI-GeneID:
125096245
NCBI-ProteinID:
XP_047578987
LinkDB
All DBs
Position
3:complement(125602540..125780130)
Genome browser
AA seq
1338 aa
AA seq
DB search
MVSCWDTGLLLCALLGGLLLTGSSSGSKLKGPELSLKGTQHVMQAGQTLYLKCRGEAAHS
WSLPETVREESKRLSIAKSACGRNGKQFCSTLTLNAAQANHTGFYSCKYLSIPASKKKKT
ESTIYIFINDTGRPFLEMHSEIPEIIYMTEGREIVIPCRVTSPNITVTLKKFPLDTLIPD
GKRISWDSRKGFIIANATYREIGLLTCETTVNGHLYKSNYLTYRQTNTIQDVQISTPSPV
KLLRGHTLTLNCTATTALNTRVQMTWSYPGETKKRASIRQRIGQRTSVAIVFYSVLTIDK
VQNRDKGLYTCNVKSGPSFKSVNTSVHIYDKAFITVKHRKQHVLETIAGKRSYRLSVKVK
AFPSPEVLWLKDGFPVTEKSPRYLVHGYALIIKDVTAEDAGDYTVLLAIKQYGVFQNLTT
TLIVNVKPQIYEKAVSSFLDPTLYLLGSRQILTCTIYGIPQPTVTWYWCPCNHSHSKARY
DFCSNNEESLILDPDSNLGNRIESITQRTAVIEGKNKTASTLVVADSRISGIYSCMASNK
VGTVERNISFYVTDVPNGFHVNLEKMPTEGEDLKLSCTVNKFLYRDITWILLRTVKNRTM
HHSISKQKMAVTKENSITLNVTIKNVSLEDSGTYACRARNIYTGEEILQKKEVTIRDQEA
PHLLRNLSDHTVAISSSTTLDCHATGVPEPQITWFKNNHKIQQEPGIILGPGSSTLFIER
VTEEDEGVYHCKATNQKGSVESSAYLTVQGTSDKSNLELITLTCTCVAATLFWLLLTLFI
RKLKRSSSEIKTDYLSIIMDPDEVPLDEQCERLPYDASKWEFARERLKLGKSLGRGAFGK
VVQASAFGIKKSPTCRTVAVKMLKEGATASEYKALMTELKILTHIGHHLNVVNLLGACTK
QGGPLMVIVEYCKYGNLSNYLKSKRDLFFLNKDAALHVEPKTEKMESDLEQDKKPRLDSV
TSSESFASSGFQEDKSLSDVEEEEDSDDFYKQPITMEDLISYSFQVARGMEFLSSRKCIH
RDLAARNILLSENNVVKICDFGLARDIYKNPDYVRKGDTRLPLKWMAPESIFDKIYSTKS
DVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLKEGMRMRAPQYATPEIYQIMLDCWHKD
PKERPRFAELVEKLGDLLQANVQQDGKDYIPLNAILTGNSGFTYSPPAFSDDFFKEEISH
PKFNSGSSDNVRYVNAFNFMSLERIKTFEELSPNTTSIFDDYQVDSSTLLASPLLKRFTW
AESKPKASVKTDLRVTSKSKESGLSDLMPPASCPSGCGHINRGRRRFTYDNSELEKKIPC
CSPPPDYNSVVLYSTPPV
NT seq
4017 nt
NT seq
+upstream
nt +downstream
nt
atggtcagctgctgggacaccgggctcctgctgtgcgcgctgcttggcggtctgctgctt
acaggatctagttcaggttcaaaattaaaaggtcctgaactgagtttaaaaggcacccag
cacgtcatgcaagcaggccagacactgtatctcaaatgtagaggggaagcagcccattca
tggtctttgcctgaaacagtgagagaggaaagcaaaaggctgagcatagctaaatcggcc
tgtggaaggaatggcaaacagttctgcagtactctgaccttgaacgcggctcaggcaaac
cacactggcttctacagctgcaaatatctatctatacctgcttcaaagaagaagaaaaca
gaatctactatctacatatttattaatgatacaggtagacctttcttagagatgcacagt
gaaatacccgaaattatatatatgactgaaggaagggagatcgtcatcccctgccgggtc
acatcacctaacatcactgtgactttaaaaaagtttccccttgacaccctgatcccggat
ggaaaacgaataagctgggacagtaggaagggttttataatagcaaatgcaacatacaga
gagatcggccttctgacctgtgaaacgacagtcaacggacatttgtacaagagcaactat
ctcacctatcgacaaaccaataccatccaagatgtccagataagcacgccaagcccagtc
aagttacttcgaggtcacactcttaccctcaactgcaccgctaccactgctttgaacaca
agggttcagatgacttggagttatcctggtgaaacaaagaagagagcgtctataaggcaa
cgaattggccagcgcacctccgttgccattgtgttctacagcgttcttactattgacaaa
gtacagaacagagacaaaggactttatacttgcaatgtgaagagtggcccgtcgttcaaa
tctgtgaacacgtcagtgcatatatatgataaagcattcatcacggtgaaacatcgaaaa
cagcacgtgctggagaccatagccggcaagcggtcctacaggctctctgtgaaagtgaag
gcatttccctcaccagaggttctatggttaaaagatgggttccccgtgactgagaaatct
cctcgctacctggttcatggctacgcattaattatcaaagatgtcactgcagaggacgcc
ggggattacacggtcttgctggccataaagcagtatggcgtgttccaaaaccttaccacc
actttaattgtaaatgtgaaaccgcagatctatgaaaaagccgtgtcatcctttctagac
ccgactctctatctcctgggcagcagacaaatcctgacttgtaccatttatggtatccct
caacctacagtcacatggtactggtgtccctgtaaccatagtcattccaaagcaaggtat
gacttttgctccaataatgaagagtccctaatcctggatcctgacagcaacctaggaaac
aggattgagagcatcactcagcggacagcagtaatagaaggaaagaataagacggctagc
accttggttgtggctgactctagaatttctggaatctacagttgcatggcttccaataaa
gtagggactgtggaaagaaacataagcttttatgtcacagacgtgccaaacggatttcat
gttaacttggaaaaaatgcctacagaaggagaggacctgaaactgtcttgcacagttaac
aagttcttatatagagacattacttggatcttactgcggacagttaaaaaccgaacaatg
caccacagcatcagcaagcagaaaatggccgtcacgaaagagaactccatcactctcaat
gtcaccatcaagaacgtttccctggaagattcaggcacctatgcctgcagagccaggaac
atatacacaggggaagaaatccttcagaagaaagaagttacaattagagatcaggaagcg
ccacaccttctgcgaaacctcagtgaccacacggtggccatcagcagctccactacccta
gactgtcacgctaccggcgtcccagagcctcagataacctggtttaaaaacaaccacaaa
atccagcaagaaccgggaattattttaggaccaggaagcagcacgctgtttattgaaaga
gtcacagaagaggatgaaggggtctatcactgcaaagccaccaaccagaaggggtccgtg
gaaagttccgcgtacctcactgttcaagggacctcagacaaatctaacctggagctcatc
actctgacgtgtacctgcgtggctgcgaccctcttctggctcctgttgacgctcttcatc
cgaaaactgaaaaggtcttcttctgaaataaaaacagactacctatcgatcataatggac
ccagatgaagttcccctggacgagcagtgcgagcggctcccttatgatgccagcaaatgg
gagtttgcccgggagagactgaaactgggcaagtcccttggaagaggggcttttggaaaa
gtggttcaagcttctgcatttggcattaagaagtcacccacgtgccggactgtggctgtg
aaaatgctgaaagagggggccacagccagcgagtacaaagctctgatgactgagctcaag
atcttgacccacatcggccaccatctgaatgtagtcaacctcctgggagcctgtaccaag
caaggagggcccctgatggtgattgttgaatattgcaaatatggaaatctgtccaactac
ctcaagagcaaacgagacttattctttctcaacaaggacgccgcattacacgtggagcct
aagacagaaaaaatggagtcagaccttgaacaagacaagaaaccaagactagatagtgtc
accagcagcgagagcttcgcaagctccgggtttcaggaagataaaagtctgagcgatgtt
gaggaagaggaggactctgatgatttctacaagcagcccatcactatggaagatctgatt
tcttacagtttccaagtggccagaggcatggagtttttgtcttccagaaagtgcattcat
cgggacctggcagcaagaaatattcttttatctgagaacaatgtggtgaagatttgcgat
tttggccttgcccgggatatttataagaaccccgattatgtgagaaaaggagatactcga
cttcctctgaagtggatggctcccgaatctatcttcgacaaaatctacagcaccaagagc
gacgtgtggtcttacggagttctgctatgggaaatcttctccctaggtgggtctccatac
ccgggtgtgcagatggacgaggacttctgcagccgcctgaaggaaggcatgaggatgagg
gccccccagtatgcaactcctgaaatctaccagatcatgttggactgctggcacaaagac
ccaaaagaaaggccaagatttgcagaacttgtggaaaagctaggcgatttgcttcaagca
aatgtacaacaggacggcaaggactatatcccattaaatgccatactgacaggaaatagt
gggttcacatattcacctcctgccttctctgatgacttcttcaaggaagagatttcacat
ccaaagttcaattcaggaagttctgataatgtcagatacgtaaatgctttcaatttcatg
agtctggagagaatcaaaacctttgaagaactttcaccaaacaccacctctatctttgat
gattaccaggtagacagcagcaccctgctggcctcccccttgttgaagcgcttcacctgg
gctgagagcaaacccaaggcctctgtgaagactgacttgagagtaaccagtaaaagcaag
gagtcggggctttctgacctcatgccgcctgcttcctgcccttccgggtgtgggcacatc
aacagaggaagacgcaggttcacgtatgacaattcagagctggaaaagaagattccgtgc
tgctctcctcccccagactacaactcggtggtcttatactccaccccgcctgtctaa
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