Lutra lutra (Eurasian river otter): 125103305 Help Entry 125103305         CDS       T08100                                  Name (RefSeq) adenylate cyclase type 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism llv  Lutra lutra (Eurasian river otter) Pathway llv00230   Purine metabolism llv01100   Metabolic pathways llv01522   Endocrine resistance llv04015   Rap1 signaling pathway llv04022   cGMP-PKG signaling pathway llv04024   cAMP signaling pathway llv04062   Chemokine signaling pathway llv04072   Phospholipase D signaling pathway llv04114   Oocyte meiosis llv04211   Longevity regulating pathway llv04213   Longevity regulating pathway - multiple species llv04261   Adrenergic signaling in cardiomyocytes llv04270   Vascular smooth muscle contraction llv04371   Apelin signaling pathway llv04540   Gap junction llv04611   Platelet activation llv04713   Circadian entrainment llv04714   Thermogenesis llv04723   Retrograde endocannabinoid signaling llv04724   Glutamatergic synapse llv04725   Cholinergic synapse llv04726   Serotonergic synapse llv04727   GABAergic synapse llv04728   Dopaminergic synapse llv04750   Inflammatory mediator regulation of TRP channels llv04911   Insulin secretion llv04912   GnRH signaling pathway llv04913   Ovarian steroidogenesis llv04914   Progesterone-mediated oocyte maturation llv04915   Estrogen signaling pathway llv04916   Melanogenesis llv04918   Thyroid hormone synthesis llv04921   Oxytocin signaling pathway llv04923   Regulation of lipolysis in adipocytes llv04924   Renin secretion llv04925   Aldosterone synthesis and secretion llv04926   Relaxin signaling pathway llv04927   Cortisol synthesis and secretion llv04928   Parathyroid hormone synthesis, secretion and action llv04934   Cushing syndrome llv04935   Growth hormone synthesis, secretion and action llv04970   Salivary secretion llv04971   Gastric acid secretion llv04972   Pancreatic secretion llv04976   Bile secretion llv05012   Parkinson disease llv05030   Cocaine addiction llv05031   Amphetamine addiction llv05032   Morphine addiction llv05034   Alcoholism llv05163   Human cytomegalovirus infection llv05166   Human T-cell leukemia virus 1 infection llv05200   Pathways in cancer llv05207   Chemical carcinogenesis - receptor activation llv05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:llv00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     125103305  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     125103305    04371 Apelin signaling pathway     125103305    04072 Phospholipase D signaling pathway     125103305    04024 cAMP signaling pathway     125103305    04022 cGMP-PKG signaling pathway     125103305  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     125103305   09144 Cellular community - eukaryotes    04540 Gap junction     125103305  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     125103305    04062 Chemokine signaling pathway     125103305   09152 Endocrine system    04911 Insulin secretion     125103305    04923 Regulation of lipolysis in adipocytes     125103305    04912 GnRH signaling pathway     125103305    04913 Ovarian steroidogenesis     125103305    04915 Estrogen signaling pathway     125103305    04914 Progesterone-mediated oocyte maturation     125103305    04921 Oxytocin signaling pathway     125103305    04926 Relaxin signaling pathway     125103305    04935 Growth hormone synthesis, secretion and action     125103305    04918 Thyroid hormone synthesis     125103305    04928 Parathyroid hormone synthesis, secretion and action     125103305    04916 Melanogenesis     125103305    04924 Renin secretion     125103305    04925 Aldosterone synthesis and secretion     125103305    04927 Cortisol synthesis and secretion     125103305   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     125103305    04270 Vascular smooth muscle contraction     125103305   09154 Digestive system    04970 Salivary secretion     125103305    04971 Gastric acid secretion     125103305    04972 Pancreatic secretion     125103305    04976 Bile secretion     125103305   09156 Nervous system    04724 Glutamatergic synapse     125103305    04727 GABAergic synapse     125103305    04725 Cholinergic synapse     125103305    04728 Dopaminergic synapse     125103305    04726 Serotonergic synapse     125103305    04723 Retrograde endocannabinoid signaling     125103305   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     125103305   09149 Aging    04211 Longevity regulating pathway     125103305    04213 Longevity regulating pathway - multiple species     125103305   09159 Environmental adaptation    04713 Circadian entrainment     125103305    04714 Thermogenesis     125103305  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     125103305    05207 Chemical carcinogenesis - receptor activation     125103305   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     125103305    05163 Human cytomegalovirus infection     125103305   09164 Neurodegenerative disease    05012 Parkinson disease     125103305   09165 Substance dependence    05030 Cocaine addiction     125103305    05031 Amphetamine addiction     125103305    05032 Morphine addiction     125103305    05034 Alcoholism     125103305   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     125103305   09167 Endocrine and metabolic disease    04934 Cushing syndrome     125103305   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     125103305 Enzymes [BR:llv01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      125103305 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  125103305 NCBI-ProteinID:  XP_047591209 LinkDB All DBs Position 1:122634048..122782113 Genome browser AA seq 1262 aa AA seqDB search MSGSKSVSPPGYAAQTAAAPASRGGPEHRSAWGEADSRANGYPHAPGGSTRGCTKKSGGA VTPQQQQQQRLANRWRSDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQ RRGAAGGGSTRAPPAGGGGGSAAAAAATGGTEVRPRSVELGLEERRGKGSAVDELEAGAV EGDEGSGDGGSSAESGAGPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQS SLTMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILVMAVLCNRAAFHQDHMGL ACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSAL HLAIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLH SQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTS LASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEM GMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGK AGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMN RQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFL GRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQI TIVPHSVFMLSFYLTCFLLLTLVVFVSVIYSCVKLFPAPLQTLSRKIVRSKMNSTLVGVF TITLVFLSAFVNMFTCNSENLLGCLADEHNISTGQVNACHVVASASNYSLGAEQGFCHSP WPSCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELTYVLIVEVPRVTLFDNADL LVTANAIDFNNNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWK LQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIAN FSEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDST YDKVGKSHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIW GNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPP LS NT seq 3789 nt NT seq  +upstreamnt  +downstreamnt atgtccggctccaaaagcgtgagccccccgggctacgcggcgcagacagctgcggcgccg gcgtcccggggaggcccggaacaccgttcggcgtggggggaggcggattcccgcgccaat ggctacccccacgcccccgggggttcgacccgcggctgcaccaagaaatccgggggggcg gtgaccccgcagcagcagcagcagcagcgcttggctaaccgctggcgcagcgacgacgac gacgaccctccgctgagcggcgacgaccccctggccgggggctttggcttcagtttccgc tccaagtccgcctggcaggagcgcggcggcgacgactgcggtcgcggcagccgccggcag cggcggggcgcggccggcgggggcagcacccgggcgccccctgcgggcggcggtggcggc tcggcggctgcagctgccgcgaccggcgggacggaggtgcgccctcgctcggtggagctg ggcctggaggagcggcggggcaagggcagcgcggtggacgagctggaggccggcgccgtc gagggcgacgaagggtctggggatggcggcagctcggcagaatcaggcgcggggcccggc gcagtgctgtcgctgggcgcctgctgcctggcgctgctgcagatattccgctccaagaag ttcccgtcggataagctggagcggctgtaccagcgctacttcttccgtctgaaccagagc agcctcactatgctcatggccgtgctggtgctcgtgtgcctcgtcatgttggccttccac gcggcgcggcccccgctccagctgccctacctggcagtgctggcggctgcggtaggtgtc atcctcgtcatggctgtgctctgcaaccgcgccgccttccaccaggaccacatgggcctg gcctgctacgcgctcatcgccgtggtgctggccgtccaggtggtgggcctgctgctgccc cagccacgcagcgcctcggagggcatctggtggacggtgttcttcatctacaccatctac acgttgctgcctgtgcgcatgcgtgccgcggtactcagcggagtgctcctgtctgccctc cacctggccatagccctgcgcaccaacgcccaggaccagttcctgctcaagcagcttgtc tccaatgtcctcattttctcctgcaccaacatcgtgggtgtctgcacccactacccggct gaggtctcccagagacaggccttccaggagacccgggagtgcatccaggcacgactccac tcacaacgggagaaccagcaacaggagcggctcctgctgtctgtcctgccccgtcatgtt gccatggagatgaaagcagacatcaatgccaagcaggaggatatgatgttccataagatt tacatccagaaacatgacaacgtgagcatcctgtttgccgacatcgagggcttcaccagc ctggcatcccagtgcactgcccaggagctggtcatgaccctcaacgagctcttcgcccgc tttgacaagctggctgcggagaatcactgtttacgtattaagatcctgggggattgctat tactgtgtctctgggctgccggaagcgagggctgaccatgcccactgctgtgtggagatg ggcatggacatgattgaggccatctcgttggtccgggaggtgacaggggtgaacgtgaac atgcgtgtgggaattcacagcgggcgagtacactgcggtgtccttggtctcaggaagtgg cagttcgacgtctggtctaatgacgtcacgctggccaaccacatggaagctggaggcaag gcagggcgtatccacatcaccaaggccacgctcaactacctgaatggggactacgaggtg gagccgggctgtgggggcgagcgcaacgcctacctcaaggagcacagtatcgagaccttc ctcatcctgcgctgtacccagaagcggaaagaagaaaaggccatgattgccaagatgaat cgccagagaaccaactccattgggcacaacccaccccactggggggccgagcgtcccttc tacaaccacctggggggcaaccaggtgtccaaggagatgaagcggatgggcttcgaagac cccaaggacaagaatgcccaagaaagtgcaaaccctgaggatgaagtggatgagtttctg ggccgcgccattgacgccaggagcatcgacaggctgcggtctgagcatgtccgcaagttc ctcttgaccttcagggagcctgacttagagaagaagtactccaagcaggtggatgaccga tttggtgcctacgtggcctgtgcctcgcttgtcttcctcttcatctgctttgtccaaatc accatcgtgccccactccgtgttcatgttgagtttctacctgacctgtttcctgctgctg acgttggtggtatttgtgtccgtgatctactcctgcgtgaagctcttcccagccccactg cagaccctctccaggaagatcgtgaggtccaagatgaacagcactctggtcggcgtgttc accatcaccctcgtgttcctgtcggctttcgtcaacatgttcacgtgtaactcggagaac ctgctgggctgcctggcggacgagcacaacatcagcaccggccaggtcaacgcgtgccat gtggtggcgtcggcctccaactacagcctgggggccgagcagggcttctgccacagcccg tggcccagctgcaacttccctgagtacttcacctacagcgtgctgctcagcctgctggcc tgctccgtgttcctgcagatcagctgcatcgggaagctggtgctcatgctggccattgag ctcacatacgtgctcatcgtcgaggtgccccgcgtcacactctttgacaatgctgacctg ctggtcaccgccaatgccatagacttcaacaacaacaacgggacctcccagtgccccgag catgcgaccaaggtggcgctgaaggtggtgacgcccatcatcatctcggtgttcgtgctg gccctgtacctgcatgcccagcaagtggagtccactgcccgcctggactttctctggaaa ctgcaggccacagaggagaaggaggagatggaggagctgcaggcctacaacaggcggctg ctgcacaacatcctgcccaaggatgtggccgcccacttcctggcccgtgagcggcgcaac gacgagctctactaccagtcgtgtgagtgtgtggccgtcatgttcgcctccatcgccaac ttctctgagttctacgtggagctggaggccaataatgagggcgttgagtgcctgcggctg ctcaatgagatcattgccgactttgacgagatcatcagcgaggatcggttcaggcagctg gaaaagatcaagaccattggcagcacctacatggccgcctcaggcctcaatgactctacg tatgacaaggtgggcaagagccacatcaaagccctggccgactttgccatgaagctcatg gaccaaatgaagtacatcaatgaacactccttcaacaacttccagatgaagattgggctc aacattggccctgtggtggctggggtgatcggggctcgcaagcctcagtatgacatctgg ggcaatacagtgaacgtggccagccgcatggacagcaccggtgtgcctgaccgcatccag gtcaccacggacatgtaccaggtgctggctgccaatacttaccagctggagtgcaggggt gtggtcaaggtcaagggcaaaggcgagatgatgacctacttcctcaacggggggcccccg ctcagttag

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