Lutra lutra (Eurasian river otter): 125106206
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Entry
125106206 CDS
T08100
Name
(RefSeq) receptor tyrosine-protein kinase erbB-3
KO
K05084
receptor tyrosine-protein kinase erbB-3 [EC:
2.7.10.1
]
Organism
llv
Lutra lutra (Eurasian river otter)
Pathway
llv01521
EGFR tyrosine kinase inhibitor resistance
llv04010
MAPK signaling pathway
llv04012
ErbB signaling pathway
llv04020
Calcium signaling pathway
llv04151
PI3K-Akt signaling pathway
llv05205
Proteoglycans in cancer
llv05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
llv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
125106206
04012 ErbB signaling pathway
125106206
04020 Calcium signaling pathway
125106206
04151 PI3K-Akt signaling pathway
125106206
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
125106206
05205 Proteoglycans in cancer
125106206
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
125106206
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
llv01001
]
125106206
Enzymes [BR:
llv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
125106206
Protein kinases [BR:
llv01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
125106206
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Furin-like
Pkinase
Kinase-like
TM_ErbB1
Motif
Other DBs
NCBI-GeneID:
125106206
NCBI-ProteinID:
XP_047595890
LinkDB
All DBs
Position
8:complement(51566652..51585428)
Genome browser
AA seq
1339 aa
AA seq
DB search
MRANAALQVLGFLLNLAQGSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVM
GNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVYDGKFAIFVM
LNYNTNSSHALRQLRFTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRDRGAEIVVKDNG
RNCPPCHEACKGRCWGPRPEDCQTLTKTICAPQCNGHCFGPNPNQCCHDECAGGCSGPQD
TDCFACRLFNDSGACVRQCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTS
CVRACPPDKMEVDKNGLKICEPCGGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGN
LDFLITGLNGDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGG
RSLYNRGFSLLIMKNLNITSLGLRSLKEISAGRVYISANRQLCYHHSLNWTRLLRGPPEE
RLDIKHNRPRRDCVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEP
REFAHEAECFSCHLECRPMEGTATCNGSGSDACAQCAHFRDGPHCVSSCPSGVLGAKGPI
YKYPDAQNECRPCHENCTQGCKGPELQDCLGQTLALISKTHLAVGLTVVVGLAVIFLILG
GTFLYWRGRRIQNKRAMRRYLERGESIEPLDPSEKANKVLARIFKETELRKLKVLGSGVF
GTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQDVTDHMLAIGSLDHAHIVRLLGLCPG
SSLQLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNV
LLKSPSQVQVADFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFGKYTHQSDVWSYGVT
VWELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKE
LANEFTRMARDPPRYLVIKRESGPGIPPGAEPPALTNKELEEVELEPELELDLDLEAEED
GLAATLGSALSLPVGTLNRPRGSQSLLSPSSGYMPMNQGNLGETGQESVFCGSGERCPRP
ASLHPMPRGRLASESSEGHVTGSEAELQEKVSMCRSRSRSPRPRGDSAYHSQRHSLLTPV
TPLSPLGLEEEDVNGYVMPDAHLKGTPSSREGTLSSVGLSSVLGTEEEDEDDEYEYMNRR
RRRSPARPPRPSSLEELGYEYMDVGSDLSASLGSTQSCPLNPVPLMPAAGTTPDEDYEYM
NRRHGGGAPGGDYAAMGACPAAEQGYEEMRAFQGPGHHAPHVHCARLKTLRSLEATDSAF
DNPDYWHSRLFPKANAQRT
NT seq
4020 nt
NT seq
+upstream
nt +downstream
nt
atgagggcgaacgcggctctgcaggtgctgggctttcttctcaacctggcccagggctcg
gaggtgggcaactcccaggcagtgtgtcctgggactctgaatgggctgagtgtgacgggc
gatgccgagaaccagtaccagacgttgtacaagctctacgagaggtgtgaggtggtgatg
gggaaccttgagattgtgctcacgggacacaatgctgacctctccttcctgcagtggatc
cgagaagtgaccggctatgtcctcgtggccatgaacgagttctctacgctgccactgccc
aacctccgggtggtacgcgggactcaggtgtacgatgggaagtttgccatctttgtcatg
ttgaactataacaccaactccagccacgccctgcgccagctccgcttcactcagctcact
gagattctgtcagggggcgtttatattgagaagaatgataaactttgtcacatggacaca
atcgactggagggacatcgtgagggaccgaggtgcagagatagtggtgaaggacaatggc
aggaactgtcccccatgtcatgaggcctgcaaggggcgatgctggggtcctaggccagag
gattgccagacattgaccaagaccatctgtgcccctcaatgtaatggtcactgctttggg
cccaaccccaaccagtgctgccatgatgagtgcgcaggcggctgctcaggccctcaggac
acagactgctttgcctgtcgactcttcaatgacagtggggcctgtgtgcgccagtgtcca
cagcctctagtctacaacaagctaactttccagctggaacccaacccccacaccaagtat
cagtacggaggagtttgtgtggccagctgtccccataactttgtagtggatcaaacatct
tgtgttcgggcctgtcctcctgacaaaatggaagtagataaaaatggactcaaaatatgt
gaaccttgtggggggctctgccccaaagcctgtgaagggacaggctctgggagccgcttc
cagactgtggactctagcaacattgatggatttgtgaactgcaccaagatcctgggcaac
ctggactttcttatcactggcctcaatggagacccctggcacaagatccctgccctggac
cctgagaagctcaatgtcttccggacagtacgggagatcacaggttacctgaacatccag
tcctggcctccccacatgcacaacttcagtgtcttttccaacctgacaaccatcgggggc
agaagcctatacaaccggggtttctctttgttaatcatgaagaacttgaatataacatct
ttgggcctccgatctttgaaagaaattagtgccgggcgtgtctacataagtgcgaacagg
cagctctgctaccaccattctctgaactggaccaggcttcttcgggggcctcctgaagag
agactagacatcaagcataatcggcctcgcagagactgtgtggccgagggcaaagtgtgt
gatcccctgtgctcctctgggggatgctggggcccaggtcctggtcagtgcctctcctgt
cgaaactacagccgaggaggtgtctgtgtgacccactgcaactttctgaatggggagcct
cgtgagtttgcccatgaggctgaatgcttctcctgccacctggagtgccgacccatggag
ggtactgccacatgcaatggctcgggctctgatgcttgtgctcagtgtgcccattttcga
gatgggccccactgtgtgagcagctgccccagtggcgtccttggggccaagggtcccatc
tacaagtatccagatgctcagaatgaatgtcggccctgccacgagaattgcacccagggg
tgcaagggaccagagctacaagactgtttaggtcaaacactggcactgatcagcaaaacc
catctggcagtgggtttaacagtggtagtaggattggcagtgattttcctgatccttgga
ggcactttcctctactggcgtgggcgtcggattcagaataagagggctatgaggcgctac
ttggaacggggtgagagcatagagcctctggatcccagtgagaaggctaacaaagtcttg
gccagaatcttcaaagaaacagagctgaggaagcttaaagtgcttggctcaggcgtcttt
ggaaccgtgcacaaaggagtatggatacctgagggggaatcaatcaagattccagtctgc
attaaagtcattgaggacaagagtggacgacaaagttttcaagatgtgacggatcatatg
ctggccattggcagcctagaccatgcccacattgtacggctgctgggactgtgcccaggg
tcatctctgcagctcgtcactcagtacttgcctctgggttccctgctggatcacgtgaga
caacaccgtggagcgctggggccccagctgctgctcaattggggagtacagattgccaag
gggatgtactaccttgaggagcatggtatggtgcacaggaacctggcggcccgaaatgtg
ctactgaagtcacccagtcaggttcaggtggcagattttggggtggctgacttgctgccc
cctgatgataagcaactactacacagtgaggccaagactccaattaagtggatggccctg
gagagtatccactttgggaaatacacacaccagagtgacgtctggagttatggagtgaca
gtttgggagctgatgacctttggggcagaaccctatgctgggctacgactggctgaagta
ccagacctgctagagaagggggagcgactggcgcagccccagatctgtaccatcgatgtc
tacatggtcatggtcaagtgttggatgattgatgagaacattcgtccaacctttaaagaa
ctagccaatgagttcaccaggatggcccgagacccaccacggtatctggtcataaagaga
gagagtgggcctggaattccccctggggcagagccccctgctctgacaaacaaggaactg
gaggaggtggagctggagccagaactggagctagacctggatttggaggcagaggaggat
ggtctggcggccacactaggctctgccctcagcctgcccgtgggaacacttaatcggccc
cgtgggagccagagtcttttaagcccatcatctggatacatgcctatgaaccagggtaat
cttggggagactggccaggagtctgtattttgtgggagtggtgagcgatgcccccgtcca
gcctctttgcacccaatgccacggggacgcctggcatcagaatcctcagagggccatgtg
acaggctctgaggctgagctccaggagaaggtgtcaatgtgtaggagccggagccggagc
ccccggccacgtggagacagtgcctaccattcccagcgccatagcctgctcactcctgtc
accccactctccccactagggttagaggaagaggatgtcaatggatatgtcatgccagat
gcacacctcaaaggtactccctcctcccgggaaggtaccctttcttcagtgggcctcagt
tctgtcctgggtaccgaagaagaagatgaagatgatgagtatgagtacatgaaccggagg
agaaggcgcagtccagctcgtccccctaggcccagttctctcgaggagctgggttatgag
tacatggatgtgggatcagacctcagtgcttccctgggcagcacacagagttgcccactc
aaccctgtacccctcatgcctgctgctggcacaaccccagatgaggactatgaatatatg
aatcggcgacatggtggaggagctcccgggggagattacgcagccatgggggcctgccca
gcggctgagcaagggtatgaagagatgagagctttccaggggcctggacaccatgccccc
catgtccactgtgctcgcctcaaaactctccgtagtttagaagccactgactccgctttt
gataaccctgattactggcatagcaggcttttccccaaggctaatgctcagagaacataa
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integrated database retrieval system
