Lutra lutra (Eurasian river otter): 125108541
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Entry
125108541 CDS
T08100
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
llv
Lutra lutra (Eurasian river otter)
Pathway
llv04120
Ubiquitin mediated proteolysis
llv04144
Endocytosis
llv04330
Notch signaling pathway
llv04668
TNF signaling pathway
llv04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
llv00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
125108541
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
125108541
04668 TNF signaling pathway
125108541
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
125108541
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
125108541
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
llv04131
]
125108541
04121 Ubiquitin system [BR:
llv04121
]
125108541
Enzymes [BR:
llv01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
125108541
Membrane trafficking [BR:
llv04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
125108541
Ubiquitin system [BR:
llv04121
]
Ubiquitin ligases (E3)
HECT type E3
125108541
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
125108541
NCBI-ProteinID:
XP_047600457
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All DBs
Position
9:119843858..119974699
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AA seq
862 aa
AA seq
DB search
MSGSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIFETLKSNNMKLEEVVVTL
QLVGDKEPTETIGDLSVCLDGLQLDSEVVTNGETTCSESASQSDDGSRPKDETRTNTNGS
DEPEDAGAGENRKVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNINSNTSEGAASGLIIPLTISGGSGPRPLNPVPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFTTSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFNPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctggcagtggatcacagcttggttcaatgggtagcctgaccatgaaatcacaactt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtggaagtcacagtagatggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcaaccccttacagttatcgtcacccctgtgagtaaattacat
tttcgtgtatggagtcaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatctttgaaaccttaaagtcaaacaacatgaaacttgaggaagtagttgtgacttta
cagcttgtaggtgacaaagagccgacagagacaataggagacttgtcagtttgtcttgat
gggctgcagttagattctgaagttgttaccaatggtgaaactacatgttcagaaagtgct
tcacagagtgatgatggctccagacccaaggatgaaacaagaacaaacacaaatggatca
gatgagcctgaggatgcaggggctggtgaaaataggaaggtcaatgggaataattctcca
tcactctcaaatggtggttttaaaccttctaggcctccaagaccttcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggttccccatctgccacttctgaaagtgat
ggatccagtacaggctctctgccaccaacaaatataaattcaaatacatctgaaggagca
gcatctggattaataattcctctgactatatctggaggctcaggccctcggccattaaat
cctgtacctcaggctcccctaccacctggttgggagcagagagtggaccagcatgggcga
gtttactatgtagatcatattgaaaaaagaacaacatgggatagaccagaacctctacct
cctggctgggaacgtcgggttgacaacatgggacgaatttactatgttgaccatttcaca
agaacaacaacgtggcagaggccaacattggaatccgtccggaactatgaacagtggcag
ctccaacgtagtcagctgcaaggagcaatgcagcagtttaaccagagatttatttatggg
aatcaagatttgtttactacatcacaaaataaagaatttgatccccttggtcccctgcca
cctggatgggagaagagaacagacagcaatggtagagtatattttgtcaaccacaacact
cgtatcacacagtgggaagatcccagaagtcaaggtcaattaaatgaaaagcccttgcct
gaaggctgggaaatgagattcacagtcgatggaattccgtattttgtggaccacaataga
agaacaaccacctatatcgatccccgcactggaaaatctgccctagacaatggaccacag
atagcctatgtacgggatttcaaggcaaaagttcagtatttccggttctggtgtcagcaa
ctggccatgccacagcacataaagattacagtgacaagaaagacattgtttgaagattcc
tttcagcagataatgagcttcaatccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagagtggttctttcttttgtca
cacgaagtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcagattaatcctgcttcttacatcaatccagatcacctgaaatactttcgttttatt
ggcaggtttattgccatggctctcttccatgggaaattcatagacacaggtttttctttg
ccattctataaacgtatattgaacaaaccagttggactcaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggtttg
gaaatgtacttctctgtcgataaagaaattttaggtgaaatcaagagtcatgatttgaaa
cctaatggtggcaatattcttgtgacagaagaaaataaagaggaatatatcagaatggta
gctgaatggaggttgtctcgaggtgttgaagaacagacacaagctttctttgagggcttt
aatgaaattcttccccagcagtatttgcaatactttgatgcaaaggaattagaggtcctt
ttatgtggaatgcaagagattgacttgaatgactggcaaagacatgccatctaccgccat
tacactaggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaattgataat
gagaagagaatgagacttctgcagtttgttactggaacctgccgattgccagttggagga
tttgctgacctcatggggagtaatggaccacaaaaattctgcattgaaaaagttgggaaa
gaaaattggttacccagaagtcatacgtgttttaatcgcctggacctgccaccctacaag
agctatgagcaactgaaggaaaagctgttatttgccattgaagaaacagaaggatttgga
caagagtaa
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