KEGG   Leishmania martiniquensis: 92517157
Entry
92517157          CDS       T10333                                 
Symbol
LSCM1_07265
Name
(RefSeq) hypothetical protein
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
lmat  Leishmania martiniquensis
Pathway
lmat00270  Cysteine and methionine metabolism
lmat00450  Selenocompound metabolism
lmat00670  One carbon pool by folate
lmat01100  Metabolic pathways
lmat01110  Biosynthesis of secondary metabolites
lmat01230  Biosynthesis of amino acids
lmat04980  Cobalamin transport and metabolism
lmat04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:lmat00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    92517157 (LSCM1_07265)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    92517157 (LSCM1_07265)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    92517157 (LSCM1_07265)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    92517157 (LSCM1_07265)
   04980 Cobalamin transport and metabolism
    92517157 (LSCM1_07265)
Enzymes [BR:lmat01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     92517157 (LSCM1_07265)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding GAIN
Other DBs
NCBI-GeneID: 92517157
NCBI-ProteinID: XP_067181002
UniProt: A0A836HL66
LinkDB
Position
7:33321..37070
AA seq 1249 aa
MHGERSPLFEELEELFQRRILLLDGGMGTMLQRYKLEEEDFRGEEFKNATKDLKGNNDLL
CLTQPAKVWDVHYKYAIAGADVIETNTFNAQAVSQSDYETQHLVRRINMAAAKICRDAVE
QASRETGRRIFVAGVLGPLNRTASISPSVEHPDYRNITYDEIVAAYTEQATALLDGGVDV
LLIETVFDSLNAKAALFALNTLFDDEGYTRVPIMVSGTITDLSGRTLSGQTVDAFYSSMR
HGNIISIGLNCALGCREMRPYIERLAQISEGYVTCHPNAGLPNAMGGYDELPEDMARDIR
DFAVSGWVNLVGGCCGTTPDHIRAIARAVEGVPPRLKGQQSKTMVISGLEPLYLTDHIGF
CNIGERCNLSGSLKFKRLVKDGKWEECLSVARKQVEDGAMVLDVNMDDGLIDGVAAMTRF
LNLLASDPEVARVPIMIDSSKFHVIEAGLKCTQGTPIVNSISLKVGEEEFLRQARLIRRY
GAAVVVMAFDESGQAADYANKIRICKRAYDMLVGDGFPPESIVFDPNVLTICTGMEEHNN
YAIDFMNAAAWIKVNLPRAKVSGGISNLSFSFRGFETIRMAMHSAFLKTMIADRSLDMAI
VNAGALPVYTDIEPGLLQLVEDAIYNRTPDSAERILEYTERLKAERAAGGGTEEVKVSKV
DEWRNASVEERLSHALIKGIVEFIEDDVEEARTCGKYEQPLAIIEGPLMNGMGKVGELFG
SGKMFLPQVIKSARVMKKAVAVLVPYMEVEKAALMEGAKGMSPSRAKRVLMATVKGDVHD
IGKNIVGVVLGCNSYEVIDLGVMVPCEKILAAAKEHEVDVIGLSGLITPSLDEMVHVAKE
MRRMGFEIPLMVGGATTSKQHTAVKIHPHYHKTVHVLDASKSVVTVSNMLGSNNKEFWEE
VQETYQEIAEDYLASLRDRVYKPLAFCREHALKIDFAAHPPAPRPKKLGTITIHDYSLEK
ISGRIDWNPFFSVWQVRGTYPNRGFPKLFSCPTVGEEAKRLFADAQEMLKGIIATRSFRA
KAVVTLMPVNSVGDDIEVYKDDTRVEKIATFFGLRQQAEKERGEPYLCISDFIAPKGVAP
DYLGSLIVGIFGADKMSEGYEKDNDGYRSIMVKALADRFAEAFTEEVHRIIRTDLWGYAE
KEKTETADLITMQYQGIRPAPGYPSQPDHTEMDTMWRIGEVEERTGVKLSESYAMMPAAS
VSALVFAHAQSKYFAVGKIQKDQVKDYATRKGWSIDRTESQLGSSLAYA
NT seq 3750 nt   +upstreamnt  +downstreamnt
atgcatggagaacgtagccccctattcgaggagctggaggagctcttccagcgtcgcatc
ctcctgctcgacggcggcatgggcactatgttgcagcgctacaagctcgaggaagaagac
ttccgtggcgaggagttcaaaaacgccacaaaggatctcaagggcaacaacgacctgctc
tgtctcacacagccggcgaaggtatgggatgtgcactataagtatgctatcgccggcgcc
gacgtcattgagacgaacacgttcaacgcacaagcggtgagtcagtccgactacgagaca
cagcacctcgttcgacgaatcaacatggcggctgcgaaaatctgccgcgacgcggtagag
caagccagtcgcgagacagggcggcgcatctttgtcgccggcgtgttgggcccgctgaac
cgaacggcctcgatctcgccctccgtcgagcaccctgattatcgcaacatcacctacgac
gagattgtagctgcttacacggagcaggcgacggccctgctggacggaggcgtagatgtg
ctgctgatcgagaccgtattcgactccctcaacgccaaggcggccctctttgccctgaac
acgctctttgatgacgaaggctacacacgcgttccgattatggtgagtggcaccattaca
gacctgtctggccgaaccctcagcggccagacagtggacgcgttctactcgtcgatgcgg
cacggcaacatcatctccatcggtctcaactgcgccctgggctgccgagaaatgcgccca
tatatcgagcgtctcgcgcagattagcgagggatacgtgacgtgccacccaaacgcaggg
ctgccgaacgcgatgggtggatacgacgagctgccggaggacatggcccgtgacatccgg
gactttgctgtcagtggatgggtcaatctcgtcggcggctgctgcggcactaccccggat
cacattcgtgccattgccagggctgtggagggcgtcccgccgcgactgaagggtcagcaa
agtaagacgatggtcatcagcgggctcgagccgctgtacctcaccgaccacatcggcttc
tgcaacatcggggagcgctgcaaccttagcggctcgcttaagtttaagcgcctcgtgaag
gacgggaagtgggaggagtgcctgtcggtggcccgcaagcaagtcgaggatggagccatg
gtgctggacgtgaacatggacgacggcctcatcgatggagtggcggccatgacgcgcttc
ctgaacttgctcgcctccgacccggaggtggcgcgggtgccgataatgattgactcgtcc
aagttccatgtcatcgaggcgggtctaaagtgcacccagggcacgccgatcgtgaactcc
atctcgctcaaggtgggcgaggaggagtttctacgccaggctcgtctcatacggcgttac
ggcgccgccgtagtggtgatggctttcgatgaaagtgggcaggcggccgactacgccaac
aagatccgcatctgcaagcgtgcgtacgacatgctagtgggagacggctttccgccggag
agcattgtcttcgacccgaatgtgctgacaatctgcaccggcatggaggagcacaacaac
tacgccatagacttcatgaatgctgcggcgtggatcaaggtgaatctgcctcgcgctaag
gtgagcggtggcatctccaacctgagcttttccttccgcggcttcgagaccattcgcatg
gccatgcactcagccttcctcaagaccatgatcgctgacagaagcctcgacatggcgatc
gtgaacgcaggtgctttgccggtatacaccgacatcgagccaggcctgctgcagctggtc
gaggacgccatctacaaccgaacccccgactctgcggagcgtatccttgagtacacagaa
cggctcaaagcggaaagggcagccggcggcggcaccgaggaggtgaaggtgtccaaggta
gacgagtggcgcaacgcctcggtagaggagcgtctctcgcacgccttgatcaagggtatc
gtcgagttcatcgaggacgacgtcgaggaggcgcgtacctgcggcaagtacgagcagcca
ctggccatcatcgagggtccgttgatgaatggcatggggaaggtgggcgagctgtttggc
agtggcaagatgttcctaccccaggtgatcaagtcggcacgcgtcatgaagaaagcggtg
gcggtgctggtgccatacatggaggttgagaaggcggcccttatggaaggtgccaaaggc
atgtcgccgtctcgggcgaagcgggtgctcatggcgacagtgaagggtgatgtacatgac
atcggcaagaacatcgttggggttgtcctgggctgcaatagttacgaggtaatcgacctt
ggtgtgatggtcccttgtgaaaagatcttggcggctgcaaaggagcacgaggtagacgtc
attgggctctccggactgatcacgccttcactggacgagatggtgcacgtggcgaaagag
atgaggagaatgggcttcgaaatcccgttaatggtcggtggggcgacgacgtcgaagcag
cacacggctgtgaagatacatccgcattaccacaagacagtgcatgtgctggatgccagc
aagtccgtggtcacggtgtccaacatgctcgggagcaacaacaaggagttctgggaggag
gtgcaggagacctaccaagaaatcgcggaggactacctggcaagcctgagggaccgtgtg
tacaagcctctagcgttttgtcgcgagcatgctctgaagatcgacttcgccgcccaccct
ccggctccgcggccgaagaagcttggcaccatcaccatccatgactactcgcttgagaaa
atttccggccgcatcgattggaaccctttcttctccgtgtggcaggtgcgcggcacgtac
cctaatcgtggcttccccaaactattcagctgccccaccgtcggcgaagaggcaaagcgg
ctcttcgccgacgcgcaggagatgctcaagggcatcattgccacccgtagcttccgcgct
aaggccgtcgtcacgctgatgcctgtgaatagcgtcggcgacgacatcgaggtgtacaag
gatgacacacgtgttgagaagatcgctaccttttttggtctgcgtcagcaagcggagaaa
gagcggggcgagccgtacctgtgcatatcggacttcatcgccccgaaaggggtagcgcca
gattacctaggcagcctcattgtcggcatctttggcgcggacaagatgagcgaggggtac
gagaaggacaacgacggctaccgctccatcatggtcaaggccctagcagatcgtttcgcc
gaggcgttcacggaggaggtgcaccgtatcattcgcacagacttgtggggctacgcagag
aaagagaagaccgagacggccgacctgatcacgatgcagtaccaaggtattcgacccgca
ccagggtacccatcgcagccggaccacacagagatggacacgatgtggcgcatcggcgag
gttgaggagcgcacgggagtgaagctgtctgagtcgtacgcgatgatgccggcggcctct
gtaagcgcacttgtcttcgcgcatgcgcagtcgaagtactttgctgtgggcaaaatccag
aaggatcaagtgaaagactacgccacgcgtaaggggtggagcatagaccggacggagagc
cagctcggctcgtctctggcctatgcttga

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