KEGG   Leishmania mexicana: LMXM_11_1100
Entry
LMXM_11_1100      CDS       T02288                                 
Name
(RefSeq) putative lanosterol 14-alpha-demethylase
  KO
K05917  sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36]
Organism
lmi  Leishmania mexicana
Pathway
lmi00100  Steroid biosynthesis
lmi01100  Metabolic pathways
lmi01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:lmi00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    LMXM_11_1100
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:lmi00199]
    LMXM_11_1100
Enzymes [BR:lmi01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.154  sterol 14alpha-demethylase
     LMXM_11_1100
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.36  sterol 14alpha-demethylase (ferredoxin)
     LMXM_11_1100
Cytochrome P450 [BR:lmi00199]
 Cytochrome P450, animal type
  CYP51 family
   LMXM_11_1100
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 13454874
NCBI-ProteinID: XP_003873080
UniProt: E9ANQ3
LinkDB
Position
11:442773..444212
AA seq 479 aa
MIGELLLLLTAGLALYGWYFCKSFNTTRPTDPPVIHCTTPFVGHIIQFGKDPLGFMLSAK
KKYGGIFTMNICGNRITIVGDVHQHSKFFTPRNEILSPREVYSFMVPVFGEGVAYAAPYP
RMREQLNFLAEELTVAKFQNFAPSIQHEVRKFMKANWDKDEGEINILDDCSAMIINTACQ
CLFGEDLRRRLDARQFAQLLAKMETCLIPAAVFLPWILKLPLPQSYRCRDARAELQEILS
EIIIAREKEEAQKDSNTSDLLAGLLGAVYRDGTRMSQHEVCGMIVAAMFAGQHTSTITTT
WSLLHLMDPRNKRHLAKLHQEIDEFPAQLNYDNVMEEMPFAEQCARESIRRDPPLVMLMR
KVLKPVQVGKYVVPEGDIIACSPLLSHQDEEAFPNPREWNPERNMKLVDGAFCGFGAGVH
KCIGEKFGLLQVKTVLATVLRDYDFELLGPLPEPNYHTMVVGPTASQCRVKYIKKKAAA
NT seq 1440 nt   +upstreamnt  +downstreamnt
atgatcggcgagcttctccttctcctgaccgccggtctggcgctgtacggctggtacttc
tgcaagtccttcaacacaacccgtccgaccgatccgccggtcattcactgcacgacgcct
tttgtgggtcacatcatccagttcggcaaggatcccctgggctttatgttgagtgcgaag
aagaagtacggcggcatattcaccatgaacatctgcggcaaccgcatcactattgttggt
gacgttcaccagcacagcaagttcttcaccccgcgtaacgagattctctccccgcgtgag
gtctacagcttcatggtgcccgtctttggcgagggcgtcgcctacgccgcgccgtacccg
cgcatgcgcgagcagctcaacttcctggccgaggagctgactgtggccaagttccagaac
ttcgctccatcgatccagcacgaggtgcgcaagtttatgaaggcgaactgggacaaggac
gaaggcgagatcaacatcctcgacgactgcagcgccatgatcatcaacaccgcttgccag
tgcctcttcggcgaggacctgcgcaggcgcctggacgcgcgccagttcgcacagctgctg
gccaagatggagacctgcctcatccccgccgctgtcttcctgccgtggatcctgaaactg
ccgctgcctcagtcctaccgctgccgcgacgcccgcgctgagctgcaggaaatcctcagc
gagattatcatcgctcgcgagaaggaggaagctcagaaggacagcaacacgtcggacctg
ctcgccggtctgctgggcgccgtgtaccgcgatggcacccgcatgtctcagcacgaggtg
tgcggaatgatcgttgccgccatgtttgctggccagcacacctccactattaccaccacc
tggtccctcctgcatctgatggatcctcgcaacaagaggcacctcgcgaaactgcatcag
gagatcgacgagttcccggcgcagctgaactacgacaacgtcatggaggagatgccgttt
gcggagcagtgcgcgcgcgagtcgattcgccgcgacccgccgctcgttatgctcatgcga
aaggtgctgaagccggtccaggtgggcaagtacgtcgtgccagagggcgacatcatcgcc
tgctcgccgctcctctcgcaccaggatgaggaggcatttccgaatccgcgtgagtggaac
ccagagcgcaacatgaagctcgtcgacggtgccttctgcggctttggtgccggcgtccac
aagtgcatcggtgagaagttcggcctccttcaggtcaagacggtgctggcgacggtcttg
cgcgactacgactttgagctcctcggcccactgccggaaccgaactaccacaccatggtg
gtgggcccgacggccagccagtgccgcgtgaagtacatcaagaagaaggcggcggcttag

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