Labrus mixtus (cuckoo wrasse): 132980787 Help Entry 132980787         CDS       T10666                                  Symbol ryr1b Name (RefSeq) ryanodine receptor 1b isoform X1   KO K04961   ryanodine receptor 1 Organism lmix  Labrus mixtus (cuckoo wrasse) Pathway lmix04020   Calcium signaling pathway lmix04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:lmix00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     132980787 (ryr1b)    04020 Calcium signaling pathway     132980787 (ryr1b)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:lmix01009]     132980787 (ryr1b)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:lmix04147]     132980787 (ryr1b)    04040 Ion channels [BR:lmix04040]     132980787 (ryr1b) Protein phosphatases and associated proteins [BR:lmix01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      132980787 (ryr1b) Exosome [BR:lmix04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    132980787 (ryr1b) Ion channels [BR:lmix04040]  Voltage-gated cation channels   Ryanodine receptor    132980787 (ryr1b) SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 Ins145_P3_rec MIR SPRY RIH_assoc Ion_trans EF-hand_7 SSO2105_N Motif Other DBs NCBI-GeneID:  132980787 NCBI-ProteinID:  XP_060903096 LinkDB All DBs Position 9:25806742..25874598 Genome browser AA seq 5075 aa AA seqDB search MAEGGEGEEEIQFLRTDDQVVLQCTATVLKEQIKLCLSCEGFGDRLCFLETTSNAQNVPP DLAICSFILEQSLSVRALQEMLANRVEMMDSSQGGGHRTLLYGHAILLRHYHSSMYLSCL TTSRSLTDKLAFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLH LSYASGDLMVDASFMQTLWNMNPIMSGCELAEGFLTGGHVLRLFHGHMDECLAISTPEEG EEKRRMAHYEGGSVCSQARSLWRLEPLRISWSGSHMKWGQSFRIRHITTGRYLCLDEEKG LLVVDPERANTKLSAFCFRVSKEKVDVAQKRDVEGMGIPEIKYGESMCFVQHVSTGLWLT YAALDAKAARLGMMKRNVILHQEGHMDDALTVSRSQTEESQAARMIYSTAGLFRQFIKGL DSLGGKNKSPGAVSLPLEGVILSLQDLIFYFRPPEEELEHEEKQTKLRSLRNRQNLFQEE GMITIVLECIDRLNVYNTAAHFSEFAGEEAAESWKEIVNLLYELLASLIRGNRSNCALFC DNLDWLVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLD VLRSLCVCNGVAVRSNQNLITENLLPGRDLLLQTNIVNYVTSVRPNIFLGTCEGSTQYKK WYFEMMVDYVEPFVTAQATHLRVGWAMTEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHL WSGTVPRQVASPDAHNLAADDVVSCCLDLSVPSISFRINGHPVQGMFENFNVDGLFFPVI SFSAGVKARFLLGGRHGDFKFMAPPGYAPCYEALLPRDRMRIEPIKEYKHDFHGVRNLLG PTLSLTHTSFTPCPVDTVQIVLPPHLERIREKLAENIHELWAITRIEQGWTYGSFRDDNK KLHPCLVDFQSLPEPERNYNLQMSGETLKTLLALGCHVGMGDEKAEENLKKIKLPKTYVM SNGYKPAPLDLNHVKLTPNQNQLVEKLAENGHNVWARDRVRQGWTYSIVQDILNKRNPRL VPYNLLDERTKKTNRDSVNNAVRTLIGYGYNIEPPDQESSGHGLENTRGDKVRIFRAERS YAVTQGKWYFEFEAVTTGEMRVGWARPSVRSDNELGADELAYVFNGNKAQRWHVGNDPFG RQWLSGDVVGCMIDLTEMNIMFTLNGEMLISDSGSEMAFKDIEIGEGFIPVCALGLSQVG RINLGQNVSSLRYFAICGLQEGFEPFAINMKRDITMWFSKSLPQFVPAPTDHNHIEVSRV DGTVDSAPCLKLTHKTFGSQNANTDMLFLRLSMPVQFHETFKFPAGTTPLTRALTIPEEE VIVVEPDSEFEVLKKSASRKEQEEDKKEPSVAKELSLENEKDTMSEKGKKKGFFSKAKKV AMTPLAPPPAPPTVPRLVEDVVPDDRDDPEIIQNTTTYFYSVRIFAGQEPSGVWIGWVTP DYHQYDPSFDLSKVRSVTVTVGDDRGNIHDSMKHSNCYMVWGGDLVSTQQTRFSQEDMVV GCLVDLATGLMTFTANGKEINTFYQVEPNTKLFPAVFVQPTNQNLVQLELGKLKNIMPIS AAMFRSERNNPVPQCPPRLDVQMLTPVIWSRMPNHFLNPEVGKVSERLGWMVECTEPLIM MALHIPEENRCIDILELSERLDLMKFHYHTLMLYCAVCALGNNRVAHALCSHVDESQLFY ATENTYLPGPLRSGYYDLLISIHLESAKRARLGTNREFIVPMSQETLSIHLYPDAKKAHS LPGVGLTTCLRPKLHFSSINFVGTDPDLYTISPVFPLQELKTRAISMLTEAVLDGSQAMR DPVGGSVEFHFVPILKLISTLLIMGIFNDEDTKHILKMIDPSVFSGKEEEEEEAAEEGGA AEGEGGEAEEEEEEKDEDAELEDEGVGDEEDEELKEVEKAEHEEEDAEAKEEGKEGEEGE GGGKVDGEKAEEEKEAEAVEAEAKEEEEGPEEGLLQMKLPESVKLQMCTLLQYFCDCELR HRVEAIVAYSDQFVHNVQDNQRVRYNLLMRAFTMSAAETARRTREFRSPPQDQVLLLTNF KHCPEDEDCPVPEEVRDTLGEFHVDLLLHCGIHIEEEAEEEEVDTSLRGRLLSLVDKVKN FRKKNQPEEEQPEVEEESKPSTLQELISHTMIHWAQESFIQNPELVRLMFSLLHRQYDGL GELIRALPKAYAINAISVQDTMDLLECLGQIRSLLIVQMGPEEERLMIQSIGNIMNNKVF YQHPNLMRALGMHETVMEVMVNVLGGGGDSKEIRFPQMVTNCCRFLCYFCRISRQNQRSM FDHLSYLLQNSGIGLGMRGSTPLDVAAASCIDNNELALALQEQDLEMVVTYLAGCGLQMC PMLLSKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRRPECFGPALRG EGGNGLLAAMEEAIKISEDPARDGPTVKKDRRFMFGGEEQHEENRVHLGNAIMSFYSALI DLLGRCAPEMHLIQAGKGEALRIRAILRSLVPIEDLVGVISLPVQIPAYGKDSQIIEPKM SASFVPDHKASMVLFLDRVYGIDNQDFLLHVLEVGFLPDMRASASLDTAAFSTTEMALAL NRYLCSAVLPLLTKCAPLFAGTDHRAIMIDSMLHTIYRLSRGRALTKAQRDVIEECLMSL CKYLRPSMLQHLLRRLVFDVPILNEYAKMPLKLLTNHYERCWKYYCLPNGWANFGVTSEE ELHLSRKLFWGIFESLAHKKFDAELFKIAMPCLCAIAGAIPPDYVDATYSSHTEKKASVD AEGNFDPKPVETTNTIIPERLDAFINKFAEHTHDRWAFEKIQNNWTYGEVLDENAKTHPM LRPYKTFSEKDKEIYRWPIKESVKAMLAWEWTLDKARDGEGEVEKKATTRKISQTAQATY DPSHGYNPQPIDIGGMAISRELQSMAEQLAENYHNTWGRKKKLELQSKGGGTHPLLVPYD TLTAKEKARDREKAQDLLKFLQLNGYAVTRGLKDMEQDISSIEKRFAYGFLQKLLKWMDI AQEFIAHLEAVVSSGRVEKSPHEQEIKFFAKILLPLVNQYFKNHCLYFLSTPAKVLGSGG HSSNKEKEMIASIFCKLAALVRHRVSLFGTDASAVVNCLHILSRSLDARTVMKSGPEIVK AGLRQFFESAADDIEKMVENLKLGKVSSRNQVKGVSQNINYTTVALMPVLTSLFDHIAQH QFGDDVILDDLQISCYRLMCSIYSLGTVKTPHAEQQRPALGECLAHLAAAMPVAYLEPEL NEFNSFSVYTTKTPRERTILGLPNQVEELCTDIPVLEVLMKEIHDLAESGARYTEMPHVI EITLPMLCNYLPRWWERGFENFPDQDGQLCTSVTSEQLNHLLGSIMKIVVNNLGIDEASW MKRLAVFAQPIVSRAKPEMLKSHFIPTMEKLKKRSGKVVAEEDQLRMEGKTEVDSENGTI RDEFAVLCRDLYALYPLLIRYVDNNRARWLTCPDPDAEELFRMVGEVFIFWSKSHNFKRE EQNFVVMNEINNMSFLTADSKSKMSKAGDGESGGSEQERTKKKRRGDRYSVQTSLIVAAL KKLLPIGLNMCSPADQELINLAKIRYSLKDTDEEVREFLHNNLHLQGKVEDPAMRWQMSL YKEMSGKAEDAEDPEKVVKRVQEVSAVLYHIEVTEHPYKSKKMVWHKLLSKQRRRAVVAC FRMTPLYNIPRHRATNMFLDAYKRNWLETEGYSFEDKMIDDLSKALEEEEEEEEETETKP DPLHQLILHFSRTALTEKLKLDVDHLYMSYADIMAKSCHIGEEDEGGDQEGEEPSFEVRQ TEMEKEMEKQRLLYQQSRLHNRGGSEMVLQMISACKGEPGAMVSSTLKLGISILNGGNCD VQQKMLDYLKDKKDVGFFLSVQALMQTCSVLDLNAFERQNKAEGLGMVSEEGTNKKLERD EKVMADDEFTCDLFRFLQLLCEGHNNDFQNYLRTQTGSTTTINVIICTVDYLLRLQESIS DFYWYYSGKDIIDEPGKRNFSKAMTVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVG FLHVFAHMMMKLAQDSSQIGLLKELLDLQKDMVVMLLSLLEGNVVNGTIARQMVDMLVES SSNVEMILKFFDMFLKLKDIVASDAFRDYVTDPRGLISKKDFSKAMDSQKQYSPSEIQFL LSCSEADENEMINFEEFADRFQEPAKDIGFNIAVLLTNLSEHVPHDTRLQNFLEQAESVL NYFRPFLGRIEIMGASRKIERIYFEISEANRNQWEMPQVRESKRQFIFDVVNEGGESEKM EMFVNFCEDTIFEMNIAASISEPEGEGAEEEDDEEEEEGKGDEGEAVEGEEGNGEAEAPE STSAFADFLKSVADFFNMFTFRNLRRRYRKLRKMTVKEMVIGLATFIYTVVMGILMFVYS ICKGFFTLIWKVLFGGGLVEGAKKMTVTEILASMPDPTQDEVHGDLPPEPGAREVQDADG GVDLLDAVGGEEEEEEGEDREGGRLPGINTPGGLGDFGETTPEEPPTPEGTPLLKRKLLA ATTEGQGEGDQPATEEEAPPETEKADTENGEKTEKAEPEPEPEVKVEEPEEVEEKTVKTK AKKDKKHAEEGFELWNELEVQRIKFMNYLSRNFYNLRFLALFISFALNFILLFYKVSDSP PGEEDYEASGLFEGSGLFEGSGGGEEDGSGLDDAGGEDEDEEGPMYYFLEESTGYMEPSM SFFAIVHTLISVLCIIGYNCLKVPLVIFKREKELARKLEFDGLYVTEQPEDDDIKGQWDR LVLNTPSFPNNYWDKFVKRKVLDKYGDIYGRERIAELLGMDLVSLDVSAMTHEKKPEPDT SMFSWITSIDIKYQIWKFGVVFTDNTFLYLVWYMLMSLLGHYNNFFYACHLLDIAMGVKT LRTILSSVTHNGKQLMMTVGLLAVVVYLYTVVAFNFFRKFYNMSEDEDEPDMKCDDMMTC YLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGE LRDQQEQVREDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETE HTGQESYVWKMYQERCWDFYPAGDCFRKQYEDQLG NT seq 15228 nt NT seq  +upstreamnt  +downstreamnt atggcagaagggggagagggagaggaggagattcagttcctgcgaacggatgaccaggtc gtactgcagtgtactgccaccgtcctgaaggagcagattaagctgtgtctgtcctgtgag ggcttcggggatcgtctctgcttccttgaaaccacatccaacgctcagaatgtgcccccg gacctggccatatgcagcttcattctggagcagtctctgtcggtccgtgctctgcaggag atgctggccaacagggtggagatgatggactcgtctcaaggtggaggccatcgtacctta ctgtacggtcatgccatccttctgagacactaccactctagcatgtacctgagctgtttg actacatcccggtcactaacggacaagctggcctttgatgtgggcttacaagaagactcc actggtgaggcgtgttggtggaccattcatccagcctctaaacaaaggtctgagggtgag aaggtcagggtgggtgatgacctcatccttgtcagcgtgtcctctgagagatacctgcac ttatcctacgccagtggagatctgatggttgacgcctccttcatgcaaacactgtggaac atgaacccaatcatgtctggctgcgagctagccgaggggtttctgacaggaggtcacgtt ctcaggctcttccacggccacatggacgagtgtctggccatctccacacccgaggaaggg gaagaaaagcgaaggatggctcactatgaaggcggctctgtgtgcagtcaagctcgatcc ctgtggaggttggagcctctcagaatcagctggagtggtagccatatgaagtgggggcag tctttccgtattcgccacatcaccacaggccggtacctgtgtctggatgaggagaaaggt ctgttggttgtcgacccagagagggcaaacaccaaactatctgctttctgcttccgcgtg tcaaaggaaaaggtggatgtggctcagaagcgcgacgttgaaggaatgggcattcccgag ataaagtatggagagtccatgtgcttcgtccagcatgtgtccaccggcctgtggctcaca tacgccgccctggatgccaaagctgctcgtttgggaatgatgaagagaaacgtcattctg caccaagagggtcatatggatgatgctctaacggtgtcccgctcccaaacggaagagtcc caggctgctcgaatgatttacagcactgcgggcctcttcaggcagttcatcaagggtttg gactctctgggtgggaagaacaagtcgccgggggccgtgtcacttcctctagagggggtc atcctctctcttcaggatctcatcttctacttccgtcctcccgaggaagagctggagcac gaggagaagcagaccaaactccgctcgctccgcaacaggcagaacctcttccaagaggag ggaatgatcaccatcgtgctggagtgcatcgaccgcctgaatgtctacaacaccgctgcc cacttttctgaatttgccggggaagaagctgccgagtcctggaaggagattgtcaacctg ctttatgagctgctggcttctctaattagaggaaaccgctctaattgtgcgttgttttgt gacaacctggactggctggtcagcaagctggatcgactggaggcctcttcaggtattctt gaggtgctgtactgtgtgctcattgaaagccctgaagttctgaacatcattcaggagaac cacattaagtccatcatctctctcctggacaagcatggaaggaaccacaaggtcctggat gtcttgcgctctctttgtgtgtgtaatggtgtcgctgtgaggtccaaccagaatctcatc actgaaaacctgcttccaggtcgcgaccttttgctgcagactaacattgtaaactatgtc accagtgtaagacccaacatcttcctgggtacatgcgaggggtctacgcagtataagaag tggtactttgagatgatggtagactatgtggaaccctttgtgacggcgcaggctacccac ctccgcgtgggctgggctatgactgagggctacagcccctacccaggagggggagagggc tggggaggcaacggtgtgggagatgacctctactcttatggcttcgatggactgcatcta tggtcaggtaccgtaccccgccaggtggcttcgcctgacgcacacaacctcgccgcagac gatgttgtcagctgctgtctggatctgagcgtgccgagtatttccttccgtataaacggc cacccagttcagggcatgtttgaaaacttcaatgtggatggcctcttcttccctgtcatc agcttctcggctggagtcaaggctcgcttcctccttggcggtcgtcatggagactttaag ttcatggccccgcctggctacgccccatgctatgaggccctgctgcccagagacaggatg cgcattgaacccatcaaggagtacaagcatgactttcatggggtgcgcaacctgctgggt ccaaccctgtccctcacccacacctcgttcaccccctgtcccgttgacactgttcagatt gtgttgccgccccacttggagcgtatccgggaaaagctggcagaaaatattcacgagctc tgggctatcacccgtattgagcagggctggacctatgggtctttcagggatgacaacaag aaactccatccttgtctggtggactttcagagtctccctgaaccggagaggaactacaac ctgcagatgtccggcgagactctaaagactctcttggccctgggttgccatgttggtatg ggtgatgagaaagcagaggagaatctcaagaagatcaagctgcccaagacctatgtgatg agcaacggatacaagcctgccccccttgacctcaaccatgtcaaactaacaccaaaccag aaccagctggtggaaaaactggcagaaaatgggcataatgtttgggcaagggaccgtgta cggcaaggatggacttacagtattgtgcaggacatcttaaataagcgaaaccctcgtctg gtaccatacaacctgctggacgagagaacaaagaaaaccaaccgagacagtgttaacaac gctgtccgcaccctcatcggttacggctacaacattgagcctccagatcaggagagctct ggccacggcctcgagaacacccgcggggacaaagtacgaatcttcagggcagagaggtcg tacgctgtcacccaagggaagtggtactttgagtttgaggcggtgacaacaggggagatg agagtgggctgggcgcgtcccagtgtgcgctccgacaatgagctgggagcagatgaactg gcctacgtctttaacggcaacaaggctcaaaggtggcatgtcggcaacgaccccttcggt cgccagtggctgtccggtgatgtcgttggttgtatgattgacctgacggagatgaacatc atgttcacactcaatggagagatgctgatcagtgactcgggctcggagatggctttcaaa gacattgaaattggggaaggttttatccctgtgtgcgccctgggcctgtcacaggttgga aggattaatcttggtcagaatgtcagcagccttcgttattttgccatctgtggcttacag gaaggatttgaaccttttgccatcaatatgaagcgagacattaccatgtggttcagtaaa agtctgccccagtttgtgcctgctcccactgatcacaatcatattgaggtctccagagta gacgggactgtggacagcgccccatgtctaaagctcacccataagacattcggctcgcag aacgcaaataccgatatgctgttcctgagactcagcatgccggtccagttccacgagacc ttcaagttcccggcgggcaccacccctcttacccgggccctcaccataccagaggaggaa gtgatagtggtggagcccgactctgagtttgaagttctgaaaaagtccgccagccgcaag gagcaggaggaggataagaaggagccgtctgtggccaaggagctgtcgttggaaaatgag aaggacacgatgtcggaaaagggaaagaaaaaaggattcttctctaaggccaagaaggta gccatgacgcctcttgcccctcctcctgcccctccaactgtgcctcgcttggtggaagat gtggtccctgatgacagagatgacccagagatcatccagaataccaccacttatttctat tcggtgaggatatttgctggacaggagccttctggtgtctggattggctgggtcactcct gactaccatcagtatgatccatcctttgacctctccaaagtgcgcagcgtcactgttacc gtgggagacgacagaggcaacatacacgacagcatgaagcacagtaactgctacatggtg tggggaggggacctggtcagcacgcagcagacccgcttcagccaggaggacatggtggtt ggctgtttggtcgacctggcgacaggtctcatgaccttcacagcaaatggaaaggagata aacaccttttaccaggtggagcccaacaccaagctgtttcctgccgtcttcgttcagccc accaatcagaaccttgtgcagctggagctgggcaaactcaagaacataatgccgatctca gcagccatgttccgcagcgaacgcaacaaccccgtcccccagtgtcccccaaggctggat gtccagatgctgaccccagtcatctggagtcgcatgcccaatcacttccttaacccggaa gtgggcaaagtgagcgagaggctgggctggatggtggagtgtactgaacctctcatcatg atggctctgcacatccctgaggagaacaggtgcatagacatcttggagttatcagagcgt ctggatctgatgaagttccactaccacaccctcatgctctactgtgctgtctgtgcactt gggaataaccgtgtggctcatgccctgtgcagccatgtggatgaatcccagcttttctat gccaccgagaacacctacctgcccggacctctccgcagtggctactatgacctgctcatc agtattcaccttgagtctgcaaagcgggcacgcctcggcaccaacagagagtttatagtc cccatgtctcaggagactctgagcatccacctctatcctgacgctaagaaggcccattct ctccccggtgttggcctcactacctgcttacgccccaagctacatttctcctccatcaac tttgttggcacggaccctgacctgtataccatcagccccgttttccccctgcaggagctg aagaccagggcgatcagcatgttaactgaagctgtgttggatggtagccaggcgatgcgg gatccagtcggaggcagtgtggagttccactttgtcccgatcctgaagctcataagcaca ctgctcataatgggcatcttcaacgacgaggacaccaagcacatcctgaagatgatcgac ccgagtgttttcagtgggaaagaggaggaggaggaggaggcagctgaagagggaggagcc gccgaaggagagggcggagaagcagaggaggaggaggaggaaaaagacgaggacgccgag ctggaggacgaaggggttggcgacgaggaagacgaggagctgaaagaagtagagaaggca gaacacgaggaggaagacgccgaagctaaggaggagggaaaggaaggggaggagggagag ggaggaggaaaagtggacggagagaaggcggaggaggagaaggaggcagaggcagtggag gcagaagcaaaagaagaggaggagggtcctgaagagggactactccagatgaagctgcca gaatctgtcaagctgcagatgtgcacgctcttgcagtacttctgcgactgtgagctacgt cacagagtggaggctatcgtagcctactccgaccagttcgtccataacgttcaggacaac caacgtgttcgttacaacctgctgatgagagccttcaccatgtccgctgctgagactgca cgaaggacccgcgagttccgttcaccaccacaagaccaggttcttttgctgacaaacttt aagcattgtccagaggatgaggattgtcccgtgcctgaggaggtgcgagacactctggga gagttccacgttgacctcctgcttcactgtggtatacatattgaggaggaggccgaggag gaggaggtggatacctcactgaggggcagactcctcagtctggtcgacaaggtcaagaac tttcgcaaaaagaatcagccggaggaggagcagccggaggtcgaggaggaatcaaaacca agcaccctccaggagctgatctcccacaccatgatccactgggcccaggagtcattcatt cagaaccctgagctcgtgcgtctgatgttcagcctgctccaccggcagtacgacggcctc ggggagctgatccgagcgctgcccaaagcctacgccatcaacgccatatctgttcaggac accatggacctgcttgagtgtttgggacagatacggtcactgctcattgttcagatgggc ccagaagaggagagactcatgatccagagcatcgggaacatcatgaacaacaaggtgttc taccaacatcctaatctgatgagagctcttggtatgcacgagaccgtcatggaggtgatg gtcaatgtgttaggtggtggaggagactcaaaggagattcgattcccccaaatggtcacc aactgctgtcgcttcctgtgttacttctgtcgtatcagccgacagaatcagcgctccatg tttgaccatctgagctacctgctacagaacagtggcatcggcttgggcatgcgtgggtcc acacctctggatgtggctgcagcttcctgcattgataacaatgagctggccttggcacta caagagcaggacctggaaatggtggtgacgtacttggctggctgtggactgcagatgtgt ccaatgctcctttctaaaggctaccctgacatcggctggaacccttgtggaggagagaga tacctggacttcctccgctttgccgtctttgttaatggagagagcgtggaggagaatgcc aatgtcgtcgtgcgtctgctcatccgtcggccggagtgcttcggcccagccctgagagga gagggtggtaatggtctgctggctgccatggaggaggccatcaagatctcagaggatccg gcgagagacgggcccactgtcaaaaaagacaggcgcttcatgtttggtggagaggaacag cacgaggaaaaccgtgtacatctgggaaatgccatcatgtcgttctactcagccctcatt gatttgctgggtcgctgtgcccctgagatgcatctgatccaagcaggcaagggtgaggct ttaaggatcagggccatcctgaggtctctggtgcccatagaggacctggtgggagtcatc agcttgcctgtgcagattcctgcttacggcaaagacagtcagattattgagccaaagatg tctgccagttttgtgccggaccacaaggcctccatggtgctgttccttgatagagtgtat gggattgacaaccaggacttcttgcttcatgtgctggaggttggattccttcctgacatg cgagcttcagcttctctggacacagctgcattcagtacaactgaaatggccttggcactg aaccgctacctctgttcagctgtgttgcctctactcaccaagtgtgccccattgtttgct gggactgaccaccgggccatcatgatcgactccatgctccacaccatctatcgtttgtcc cgtggccgagccctcaccaaggctcagagggacgtcattgaggagtgcctcatgtcgctt tgcaagtatcttcgaccctccatgctgcagcatctgctcagacgccttgtatttgatgtg cccatccttaacgaatatgcaaagatgcctctcaagttgttgacgaatcactatgagcgc tgttggaagtactactgcttgcctaatggatgggctaatttcggggtgacctcagaggag gagctgcatctttctcgtaaactcttttggggaatctttgaatctttggcacacaagaaa tttgatgctgagctcttcaagatagccatgccttgcctctgtgctatagcaggagccata ccacccgactatgtggatgccacttactcctctcacactgaaaagaaagcttctgtggat gctgagggcaactttgatcccaaaccagtggagaccaccaacaccatcatccctgagagg ctggacgccttcattaacaagtttgcagagcacacccatgacagatgggcttttgaaaag attcagaacaactggacctatggagaggtgttagatgagaacgctaagactcacccgatg ctcaggccttataaaaccttctctgaaaaggacaaggaaatataccgttggccaatcaaa gaatccgtcaaagccatgctggcctgggagtggaccttggacaaagccagggatggggag ggagaagtggagaagaaggccacgacccgcaagatctcccaaactgctcaggccacatat gatcccagtcacggatacaacccccagcccatagacatcggaggaatggccatatccaga gagctgcagtccatggctgagcagctggctgagaactaccacaacacctggggcaggaag aagaagttggagctacagtccaaaggcggtggcacccatcctttgcttgtgccttatgac acgctgacggcgaaagagaaggccagggacagagagaaggcccaggacctgctcaaattc ctccagctcaatggatatgctgtgacaaggggcctgaaggacatggagcaggatatttcc tccattgagaagcgtttcgcctatggcttccttcaaaagcttctgaaatggatggacatc gcccaggagttcattgctcatcttgaggctgtggttagcagtggtcgagtggaaaagtcc ccacatgagcaagagatcaaattctttgccaagatcctgttgcccctggtaaaccagtac ttcaagaaccactgcctctacttcctctccactcctgctaaagttttgggtagtggaggg cattcttccaataaggagaaggagatgattgccagtatcttctgtaagttggctgctttg gtgaggcacagagtttccctttttggaacggatgcaagtgcagtggttaactgcctgcac atcctctcacgatcactggatgccaggactgttatgaaatcaggccctgaaattgtcaag gccggcctgcgtcagttctttgagagtgctgccgatgacattgaaaagatggttgagaat ttgaaactgggcaaagtgtccagtcgaaaccaggtaaagggtgtgtcccagaacatcaac tacaccaccgttgccctgatgccagtccttacgtcactgtttgaccatatcgcccagcac cagtttggagatgatgtcatattggacgacttgcaaatatcctgctatcgtttaatgtgc agcatctattctctgggcacagtgaagactccacatgcagagcaacagcgaccagctctt ggcgagtgcttggctcacttagcagctgctatgccagtggcctaccttgagccagaacta aatgagttcaactcattttctgtctacaccaccaagactcctagagagagaaccattttg ggtcttcccaaccaagtggaggagctttgcactgacatcccagtgctggaggtcctgatg aaggagatccatgacctggctgagtctggagctcgctacacagaaatgccccatgtgatt gagatcaccctgcccatgttgtgtaactacctcccgcgctggtgggagaggggcttcgag aatttccctgatcaggacggtcagctctgcacctcggtcacctccgagcagctcaaccat ctgctgggtagcatcatgaagattgtggtcaacaacctgggtatagatgaggcctcctgg atgaagagattggcagtgttcgcccagcccattgtcagcagggctaaaccagagatgctt aaatcacacttcatccccaccatggaaaagctgaagaagcgttctgggaaggtggtggcg gaggaggatcagctgcgcatggagggcaagacagaggtggatagtgagaatggaaccatc agggatgagtttgctgtgctctgtcgggacctgtacgctctctacccattgctcatccgc tacgtggacaataacagggcaaggtggttgacttgtccagacccagatgcagaggaactt ttcaggatggtcggagaggtctttatattctggtctaaatcccataacttcaaacgagag gagcagaactttgtggtgatgaatgaaatcaacaacatgtcctttctgactgcagacagt aagagcaagatgagcaaggccggagacggagagtctggaggctcagagcaggagcgtacc aagaagaagcggcggggggatcgctactctgtgcagacctcgctcatcgtcgcagcatta aagaagctgcttcccatcggcctcaatatgtgctctcctgcagaccaggagctcatcaat ctcgccaagatcagatactcactgaaagacacagatgaagaggtgagggagtttttgcac aacaatcttcatctgcaaggcaaggtggaggacccagccatgcgctggcagatgtctctt tacaaagagatgtctggtaaggcggaagatgctgaggaccctgagaaggtggtgaaaagg gttcaagaggtgtcggctgtcctctaccacattgaagtgactgagcatccctacaagtca aagaaaatggtatggcacaagctgctgtccaaacagcgtcgcagggctgtggtggcctgt ttcaggatgacgcccctgtacaacatccccaggcacagggcgaccaacatgtttttggac gcttacaagcgcaactggttagagaccgaaggttactcatttgaagacaagatgattgac gacttatccaaagccttggaggaagaggaggaagaggaagaggagactgagacgaagcct gacccccttcatcagctgattcttcatttcagccgaacagctctgacagagaagcttaaa ctcgacgttgaccatctctatatgtcgtatgctgatatcatggcaaagagctgtcacatt ggtgaggaggacgaagggggagatcaggagggggaggagccatcctttgaggtgcggcag acagagatggaaaaggagatggagaaacagaggcttctgtaccagcagtcccgtctacac aaccgtggaggttcagagatggtgctgcagatgataagtgcctgtaaaggcgagcctgga gccatggtttcttccacactcaaactgggaatctccatcctcaatggaggcaactgtgat gtacagcagaaaatgctggactatctgaaggataaaaaggatgtgggatttttccttagc gttcaggctctgatgcagacctgcagcgttttggacctgaatgcttttgagagacagaac aaggctgagggccttgggatggtttcagaggagggcaccaataagaagctagaacgtgat gagaaagtgatggcggacgatgaatttacgtgtgacctcttccgtttcctccagctactt tgtgagggtcataataacgatttccagaactacctgagaacacagacaggcagcaccact accatcaatgtgatcatctgcactgtggactaccttcttcgcctacaggagtcgatcagc gacttttactggtactactcaggaaaagacatcatcgatgagcctgggaagaggaacttc tccaaagcaatgactgtggccaaacaggtcttcaacagcttgactgaatatatccagggt ccgtgcaccggtaaccagcagtctctggctcacagcaggctgtgggacgctgttgtcggc ttcctgcacgtctttgctcatatgatgatgaaactcgctcaggactccagtcaaattgga ctattgaaggagctgttggatctgcagaaggacatggtggtgatgcttctgtctctgctt gaaggcaatgtggtgaatggcaccattgcgaggcagatggttgacatgttggtggagtcc tccagcaacgtggagatgatcctgaaattcttcgacatgttcctcaagctgaaggacatc gtggcatccgacgccttcagagactatgtgaccgaccctcgtgggctaatttccaagaag gacttctccaaggccatggacagccagaagcaatattccccctcggaaatccagttcctg ctctcctgctcggaggccgacgagaacgaaatgatcaactttgaggagtttgccgaccgt ttccaggagccagccaaagacattggtttcaacatcgctgttctgctcacaaacttgtca gagcacgttccccacgacactcgccttcagaacttcctggagcaggcggagagcgtgctc aactacttccgccctttcctcggtcgcattgagatcatgggagccagcaggaagatcgag cgcatctactttgaaatcagcgaggcgaacagaaaccagtgggaaatgccgcaagtccga gagtccaagcggcagttcatcttcgacgtggtcaatgagggcggcgagagtgagaagatg gagatgtttgtgaacttttgcgaggacaccatctttgagatgaacattgccgcgtcgatt tccgagccggagggagaaggtgcggaagaagaagacgacgaggaggaagaggagggtaag ggagatgaaggagaggccgtagaaggcgaagagggcaacggagaagccgaagctccagag tcgacctcggcctttgcagactttttgaagagcgtggccgacttcttcaacatgttcacc ttccgtaacctgcggcgacggtaccgcaaactccgtaaaatgacggtgaaggagatggtg atcggcctggctacgtttatttacaccgtcgtgatgggtatcctgatgtttgtttacagc atatgtaagggcttcttcacactcatatggaaggtgctgttcggtggaggcttagtggag ggcgccaagaagatgactgtgacagaaatcctagccagtatgccggatccaacgcaggat gaagtccacggagacctgccacctgaaccgggagctagagaggtccaagacgcggacgga ggggtggacttgttagatgctgtgggaggagaagaggaagaggaggaaggcgaggacagg gaaggtggacgcctgcctggtatcaatactcccgggggacttggagacttcggtgagacg acgcctgaagagccccctactccagagggaacaccgctgctgaagagaaaactgttggct gctacaacagagggacaaggagagggagaccaacccgcaactgaagaggaggcccctcca gagactgagaaggcagacactgaaaatggagagaagacggagaaggcagagcctgaaccg gaacctgaggtgaaggtggaagagcccgaggaggtcgaggagaagactgtgaagaccaag gcgaagaaggacaagaaacatgcagaggagggctttgagctgtggaatgaactcgaggtt cagaggattaagttcatgaactacctttctcgcaacttctacaaccttcgattcttggct ctgttcatctccttcgctctcaatttcatcctgctcttctacaaggtgtccgacagtcct ccaggcgaggaggactatgaggcttctggtctgtttgagggctctggcctgtttgaaggc tctggtggtggtgaggaggatggatccggactggacgatgcagggggagaagatgaggat gaagaaggtcccatgtactacttccttgaagagagcacaggctacatggagccgtccatg tctttcttcgctatcgtccacaccctcatctccgtcctctgcatcattggatacaactgc ctcaaggtccctctggttatcttcaagagagagaaggaactggccagaaagctggagttt gatggtctttatgtcactgagcagcctgaagacgacgacatcaagggccagtgggacagg ctggtgctaaacactccgtctttccctaacaactactgggacaagtttgtgaaaagaaag gtgctggataaatatggtgacatctacggcagagagaggattgctgagttgctcggtatg gacttggtttcgctggacgtcagcgccatgacgcatgaaaagaagcctgagccagacacc tcgatgttcagctggattacatctattgacatcaagtaccagatctggaagtttggtgtt gttttcactgataataccttcctctacctggtttggtacatgttgatgtccctgctcgga cactacaacaacttcttctacgcctgccatcttctggacatcgccatgggtgtgaaaacc ctgcgcaccattctgtcttctgtgactcacaacgggaaacagctgatgatgaccgtgggt ttgctggctgtagtggtctacctgtacaccgttgtagcctttaacttcttccgcaagttc tacaacatgagcgaggatgaagacgagccggacatgaagtgtgatgacatgatgacttgt tacctgttccacatgtatgttggcgtacgtgctggtggaggcattggagatgaaattgag gacccggccggggatgaatacgagctctaccgagtcgtctttgacatcactttcttcttc tttgtcatcgtcatcctgctggctatcatccagggtctgatcattgatgcctttggagag ctgagagaccagcaggagcaggtcagagaggacatggagacaaagtgtttcatctgcgga atcggaagtgactactttgacacgacaccgcacggctttgaaacacacaccctagaagaa cacaacttagccaactacatgttcttcttgatgtatctcatcaataaagatgaaacagaa cacacgggacaggagtcgtatgtgtggaagatgtaccaggagcgatgctgggacttctac cctgctggagactgcttcaggaagcagtatgaggatcagctgggataa

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