Labrus mixtus (cuckoo wrasse): 132988730 Help Entry 132988730         CDS       T10666                                  Name (RefSeq) ryanodine receptor 1-like   KO K04961   ryanodine receptor 1 Organism lmix  Labrus mixtus (cuckoo wrasse) Pathway lmix04020   Calcium signaling pathway lmix04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:lmix00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     132988730    04020 Calcium signaling pathway     132988730  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:lmix01009]     132988730   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:lmix04147]     132988730    04040 Ion channels [BR:lmix04040]     132988730 Protein phosphatases and associated proteins [BR:lmix01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      132988730 Exosome [BR:lmix04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    132988730 Ion channels [BR:lmix04040]  Voltage-gated cation channels   Ryanodine receptor    132988730 SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 Ins145_P3_rec MIR SPRY RIH_assoc Ion_trans EF-hand_7 Motif Other DBs NCBI-GeneID:  132988730 NCBI-ProteinID:  XP_060912286 LinkDB All DBs Position 14:complement(7892066..7941517) Genome browser AA seq 5071 aa AA seqDB search MAEGADGEEEIQFLRTDDQVVLQCTAAILKEQIKLCLSCEGFGNRLCFLETTSNAQNVPP DLAICCFILEQSLSVRALQEMLSNTSVDEAVDLDKWSSQGGGHRTLLYGHAILLKHTHSS MYLSCLTTSRSLTDKLAFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVS SERYLHLSYASGDLMVDASFMQTLWTMTPVMSGCELAEGFLTGGYVLRLFHGHMDECLAI PGADQGDDQRRVAHYEGGAVCSHARSLWRLEPLRIAWSGGHIKWGQSFRIRHITTGRYLL LDEEKGLLLVDAEKANSKMSAFCFRISKEKIEVIQKRDVEGMGIPEIKYGESMCFVQHAS SGLWLTYAAVDAKSARLGPLKRKAILHKEGHMDDALTVARSQTEEYQAARMIYSTTGLFN QFIKGLDALNGKNKSSNPQSLPMDTVVLSLQDLIFYFRPPEEELEHEDKQFKLRSLKNRQ NLFQEEGMITLVLDCVDRLNVYNTAAHFSEYAGEEAAESWKEIVNLLYELLASLIRGNRA NCALFCDNLDWLVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGR NHKVLDVLCSLCVCNGVAVRSNQNLITENLLPGRDLLLQTNIINYVTSMRPNIFLGTCEG STQYKKWYFEVMVDHVEPFLTAQPYHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLYSYG FDGLHLWSGRVPRHVATPNQHLLAAEDVVSCCLDLSVPSISFRINGHPVQGMFENFNLDG LFFPVVSFSAGITLRFLLGGRHGDFKFLPPPGYAPCYEAVLPRDRLRIEPIKEYKHDYDG VRNLLGPTQSLSHTAFTPCPVDTIQIVLPPHLERIREKLAENSHELWAVTRIEQGWTFGP FRDDNKKLHPCLIDFQGLPEPEKNYNLAMSGETLKTLLALGCHVGMGDEKAEENLKRTKL PKTFMQSNGYKPAPLDLNYVKLTPNQNTLVERLAENGHNVWARDRVRQGWTYSIVQDITN KRNPRLVPYNLLDEKTKKTNRDTVCAAVRTLLGYGYNIEPPDQESSEQGSGSSRGDKIRV FRAEKSYVITQGKWYFEFEAVTVGEMRVGWARPSVRADTELGGDELAYVFNGFKAQRWHV GNEPFGRQWLSGDVVGCMIDLTEMNIMFTLNGEMLISDSGSEMAFKDIEIGEGFIPVCSL GLSQVGRINLGQNVSSLRFFTICGLQEGFEPFAINMKRDITMWFSKSLPQFINTPTDHPH IEESRVDGTVETAPCLKVTHKTFGSQNANTDLLFFRLSMPVEFHETFKVPAGTTLLTRAL TIPEDEVVEVDPDSDFEILKKSATRKEQEEEKKEPSVPKEIPAIKNGENEKDASTEKSKK KGFLFKAKKAALISPPPVVPTMPRLMEDVVPDDRDDVDIILNTTTYYYSVRVFAGQEPSG VWVGWITPDYHQYDPHFDLSKVRNVTVTVGDDKGNIHDSIKRSNCYMVWGGEFSSSQQTR VSQEDFIIGCLIDLDTGLMTFTANGKEINTFYQVEPHTKLFPAVFVLPSSQNMIQFELGK LKNIMPISTAMFRSERKNPVPQCPPRLDVQMLTPVIWSRMPNNFLAPETGRVSERLGWIV QCQEPLTMMALHIPEENRCIDILELSERMDLLKFHYHTLKLYGSVCALGNNRVAHALCSH VDESQLFYAIENTYLPGPMRSGFYDLLISMHLESAKRNRLGTNKEFIVPMTDNTRSITLY SEKSHALPGVGLTTCLRPKLHFSSVGFVGTDPDIYTLSPVIPLQVLKTKALNMLIEAVQD GGQAMRDPVGGSVEFHFVPILKLISTLLIMGVFDDEDVTHILKMIEPTVFSGKKAEEPAE ENAKMMEEKKPQKEEAAKGEDREAVGEEDEEEYEDDGLGEEEEEEEIEEEEELEQTESIV PHEETMVETEPVNGEKGAEETEKEIKEESKEEELEQGLFQMKLPESVKLQMCTLLQYFCD CELRHRVEAITAFSDQFVSQIQFNQRHRYNELMLAFTMSAAETARKTREFRSPPQEQVNM LMNFKNCAEDEDCPVPDEVREALLIFHNALLAHCGVHIEEEEQEAEVDNSVRGRLLRLLE KVKTFREKKVEVEPEPQEDKKPSTLQELISHTMIHWAQESFIQNPELVRMMFSLLHRQYD GLGELMRALPKAYTINQVSINDTMDLLECLGQIRSLLIVQMGPEEERLMIQSIGNIMSNK VFYQHPNLMRALGMHETVMEVMVNVLGGGDSKEIRFPRVVTNCCRFLCYFCRISRQNQRS MFDHLSYLLQNSGIGLGMRGSTPLDVAAASCIDNNELALALQEQDLEMVVKYLAGCGLQS CPMLLAKGYPDIGWNPCGGEKYLDFLRFAVFVNGESVEENANVVVRLLIRRPECFGPALR GEGGNGLLAAIEEAIKISEDPARDGPSVKKDRRFPMFGGEEQHEENRVHLGNAIMSFYSA LIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPLEDLVGVISLPVQIPSFGKDNSIIEP KMSASFVPDHKAPMVLFLDRVYGIDNQDFLLHVLEVGFLPDMRAAASLDTAAFCTTEMAL ALNRYLCSAVLPLITKCAPLFAGSDHRAIMIDSMLHTIYRLSRGRAFTKAQRDIIEECLM ALCKHLRPSMLQHLLRRLVFDVPILNEYAKMPLKLLTNHYERCWKYYCLPNGWGNFGVSS EEELHLTRKLFWGIFESLAHKKFDAEIFKISMPCICAIAGAIPPDYVDASYSSKTEKKAS VDAEGNFDPKPVETTNTIIPERLDPFINKYAEYTHDKWAFEKIQNNWSYGEVLDENGKTH PMLRPYKTFSEKDKEIYRWPIKESVKAMLAWEWTIDKAREEEESEKKKTAARKISQTAQA TYDPSHGYSPQPIEITHMALSRDLQSMAEQLAENYHNTWGRKKKLELQSKGGGTHPLLVP YDTLTAKEKARDREKAHELLKFLQLNGYAVTRGLKDMESDISSIEKRFAYGFLQKLLKWM EIAQEFIAHLEAVVSSGRVEKSPHEQEIKFFAKILMPLINQYFKNHCLYFLSTPAKVLGS GGHSSNKEKEMIASIFCKMSALVRHRVSLFGTDAQAIVNCLHILARSLDARTVMKSGPEI VKAGLRSFFESAADDIEKMVENLKLGKVSKGNQQVKGVSQNINYTTIALLPVLTSLFDHV AQHQFGDDVMLDDLQMSCYRIMCSIYSLGTVKNPHVERQRPALGECLAHLAAAMPVAYLE PHLNEYNAFSVYTTKTPRERAILGLPNEVQELCPDIPELDVLLKEIGDLAESGARYTEMP HVIEITLPMLCNYLPRWWERGSENFPELENQICTDVTSEHLNQMLGSIMKIVVNNLGIDE ASWMKRLAVFSQPIVSRAKPEMLKSHFIPTMEKLKKRTSKVVAEEDHLRMEGKSEGDEED GTIRDEFAVLCRDLYALYPLLIRYVDNNRARWLTCPDPDAEELFRMVGEVFIFWSKSHNF KREEQNFVVMNEINNMSFLTADSKSKMSKGGDSEGGGSDAERTKKKKRGDRYSVQTSLIV AALKKMLPIGLNMCSPADQELINLAKIRYSLRDTDEEVREFLQNNLHLQGKVDNPSMRWQ MALYKEMAGKAEDADAPEKVVKRVQEVSAVLYHLEVTEHPFKSKKMVWHKLLSKQRRRAV VACFRMTPLYNIPRHRASNMFLEGYKRNWLHTEGYSFEDRMIDDLSKAMEQEEGDEEEEK ESKPDPLHQLILHFSRTALTEKSKLDTDHLYMAYADIMAKSCHMCEEEEGGEEMGENAED EMSFEEKEMEKQRLLYQQARLHNRGAAEMVLQMISACKGETGTMVTTTLKLGISILNGGN NEVQQKMLEYLRDKKDVGFFLSVQALMQTCSVLDLNAFERQNKAEGLGMVSEEGTNEKVM ADDEFTCDLFRFLQLLCEGHNNDFQNYLRTQTGSTTTINIIICTVDYLLRLQESISDFYW YYSGKDVIDEPGKKNFSKAMTVAKQIFNSLTEYIQGPCTGNQQSLAHSRLWDAIVGFLHV FAHMMMKLAQDSSQIGLLKELLDLQKDMVVMLLSLLEGNVVNGTIARQMVDMLVESSSNV EMILKFFDMFLKLKDIVASDAFRDYVTDPRGLISKKDFQKAMDSQKQYSPSEIQFLLSCS EADENDMIHYEEYANRFQEPAKDIGFNIAVLLTNLSEHVPHDTRLKNFLEQAESVLNYFR PFLGRIEIMGASRKIERIYFEISEVNRKQWEMPQVRESKRQFIFDVVNEGGESEKMEMFV NFCEDTIFEMNIASQISEQEEEEKGEEDDEGDEGGGEGGQGAGANGGGDEDSNGEEGQPE SSSAFADFINSMLGFLSIFTFRNLRRQYRRVRKMTIKEIVVALSTFFWTILMSILHFIYN VCKGFFMIVWQTLFGGGLVEGAKNITVTEILASMPDPTQDDVHGDGPGEPRTGEEQDTGG VTDSGETGSGEEEEEDTQEKEGGRVAGVDAPGGLGDMGVESPVEPPTPEGTPITKRKMPQ EEPEASQKPPEPVPVVEPPPEPEKAEVETGEKAEKDSPSKEEEQRVERKISAKKEKKPKR EGGFQIWTELETQRNKFMNYLSRNFYNLRFLALFLAFALNFILLFYKVSDTPPEGEEMEG SGFAEGSGMFEGSGLFEGSAEEAEGSGMSDGGDEDEEDVPLYFYLEESTGYMQPTLAFIA ALHTVISFICIIGYNCLKIPLVIFKREKELARKLEFDGLYITEQPEDDDIKGQWDRLVLN TPSFPNNYWDKFVKRKVLDKYGDIYGRERIAELLGVDLASLDVSQQHEKKQEEPDSSMFS WVTSIDIKYQIWKFGVIFTDGTFLYLCWYLIMSLLGHYNNFFYACHLLDIAMGVKTLRTI LSSVTHNGKQLMMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFH MYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQ QEQVKEDMETKCFICGIGSDYFDTTPHGFETHTFDEHNLANYMFFLMYLINKDETEHTGQ ESYVWKMYQERAWDFFPAGDCFRKQYEDQLS NT seq 15216 nt NT seq  +upstreamnt  +downstreamnt atggcagaaggtgcagatggagaggaagagattcagttcctgcgaacggatgatcaagtg gtgctacagtgcactgcagctattctgaaggagcagatcaagctgtgtctgtcctgtgaa ggattcgggaatcgtctgtgtttcctcgagaccacctcaaatgctcagaatgtccctcca gacctcgctatctgctgcttcattttggagcagtccctgtctgtacgggccttacaggag atgctgtccaacacttctgtggatgaggctgttgatttggacaaatggtcatcccaaggt ggaggccatcgaaccctgctgtacggacatgccatcctcctcaagcacactcactccagc atgtacttgagctgtttgacgacttcgcgctcactgacggacaaattggcttttgatgtg ggcttgcaggaagactccacaggggaggcctgctggtggaccatccacccagcctccaaa caaaggtcagaaggagagaaggtcagggtgggagatgacctcattctcgtcagtgtttct tcagagagatacctgcatctgtcctatgccagtggtgacttgatggtagatgcctcgttc atgcaaacactgtggaccatgacccccgtgatgtctggatgtgagctagctgaaggtttt ctgactggtggctatgtgctccgacttttccacggtcacatggatgaatgtttggcaatt cctggagctgaccaaggagatgaccagcgcagagttgctcattatgaaggaggggccgta tgcagtcatgctaggtctttgtggagacttgagccacttcgcatcgcttggagcggagga catattaaatggggccagtctttccggatacgtcacatcacaacaggcagataccttctt ctggatgaagagaaagggctgttgttggtggatgcagagaaggcaaattctaagatgtct gctttctgcttcagaatttcaaaggaaaaaatcgaagtgatacaaaagcgagatgtggaa ggcatgggcataccggaaataaagtatggagagtccatgtgctttgtgcagcatgcttca tctggcctgtggcttacatatgctgcagttgatgccaaatctgctcgtctgggtccacta aagagaaaggccattctccataaagaaggtcacatggatgatgcactcacagtggctcga tctcagacagaagagtaccaagctgcaagaatgatttacagcacgacaggcctcttcaac cagttcatcaaaggtctggatgctctaaatgggaaaaacaaatcttccaacccccaatct ctgcccatggacaccgtggttctctccctgcaggatctcatcttctacttcagacccccc gaggaggagctggaacatgaggacaaacaattcaagctccgctccctgaaaaacagacag aacctcttccaggaagagggaatgattactctcgtcctggactgtgttgatcgccttaat gtctacaacactgcagcccacttctcagagtacgctggagaggaagctgcagagtcgtgg aaggagatagtgaatttactctatgaacttctagcttctctgatccgaggtaatcgtgcc aactgtgccctgttctgtgataacctggactggctggtcagtaaactggatcgtttggag gcatcttcaggaatcctggaggtgttgtattgtgtgctgattgagagtccggaggtgctg aatatcatccaggagaatcacatcaaatccatcatctctctgctggataagcatggacgc aatcacaaggtcttggatgtgctctgttctctgtgcgtgtgtaacggggtggcagtgagg tccaatcagaatctcatcacagagaatctacttccaggtcgtgacctcttacttcaaacc aacatcatcaactatgttaccagcatgagacccaacattttcctgggaacttgtgaggga tctactcagtataagaagtggtatttcgaggtgatggtggaccatgtggagccattcctt acagctcagccttatcacctgcgtgtgggctgggctctaaccgagggctacagtccttac cctggtggaggagaaggctgggggggcaacggtgtcggagatgacctatactcctacggt tttgatgggcttcacctctggtcaggtcgtgttccacgtcatgttgccacgcccaatcag cacctcctggcggcagaggacgtggttagctgctgtttggatctgagcgtgcccagcatt tccttccgtatcaatggtcatcctgttcagggcatgtttgaaaacttcaacctggacggc ctgttcttcccagttgtcagcttctctgcaggcatcacgttgcgatttcttcttggaggt cgtcatggggatttcaagtttctcccccctccaggctacgcgccgtgctatgaagcagtt ctgccccgggaccgtctgcggattgagcccataaaggagtataagcatgattacgacggt gtccgcaacctgttgggcccgactcagtcgctctcacatacggccttcactccttgccct gtggacaccatacagattgtgcttcctcctcatttggagcgcattcgagagaagcttgca gaaaatagccacgagttatgggctgttactcggattgaacaagggtggacctttggaccg tttcgtgatgacaacaagaagctgcacccctgcctgatagattttcagggtctgcctgaa ccagagaagaactacaacttagcaatgtccggggagacacttaagactctactggcacta ggctgtcatgtagggatgggagatgagaaagcagaggagaatctaaaaaggaccaaactc cccaaaactttcatgcagagtaatggatataagccagcccctctggacctaaactatgtc aagctgactcctaaccagaacactctagtggagagactggcagaaaacggacacaacgtc tgggcaagagacagagttcgtcagggatggacatacagtattgtgcaggatataacgaac aagcgcaatccccgtttggtcccttacaacctactggatgaaaagactaaaaagaccaac agagacacggtttgtgcagctgttcgcactctcctcggatatggttacaacatagagccg cctgaccaggagagcagcgagcaaggatcaggcagctcccgtggagataagatcagagtg ttcagagcagagaaatcttacgtcatcactcaggggaagtggtactttgagtttgaagct gtgactgtcggggaaatgagagtgggctgggccaggccgagcgtccgtgcagacactgaa cttggtggggatgagttggcatatgtcttcaacggcttcaaggcccaacgttggcacgtg gggaatgaaccattcggccgtcagtggctgtctggcgacgtggtgggttgcatgattgac ctcactgagatgaacatcatgttcacactcaatggagaaatgttgatcagcgactcgggc tcagagatggcctttaaggatatcgagataggagagggcttcatacccgtgtgcagtctg ggcctgtctcaggttggcaggatcaacttgggtcagaacgtcagcagtctccgtttcttc accatctgcggcctgcaggagggatttgaaccctttgctatcaacatgaaaagagacatt accatgtggttcagcaagagcctgccacagttcatcaatacacctactgatcatccccac attgaggagtcccgtgttgatgggacggtggaaacagccccttgtctcaaagtgacccac aagacatttggatctcagaacgccaacacagatctgctgttcttcagactcagcatgcca gttgagttccacgagaccttcaaagtcccagctggaaccaccctccttactcgtgcgctg actattcctgaggatgaggtggtggaggtggacccggactctgactttgaaatcctcaaa aagtcagctactcgcaaagagcaggaggaggagaagaaagagccctctgtgcccaaagag atccccgccatcaagaatggggagaacgagaaagatgcctccactgagaagagcaagaag aaagggttcctcttcaaggctaaaaaagctgcattgatatctccaccccctgttgttccc accatgcctcgcttaatggaagatgtggtgccggatgacagggatgatgtcgacatcatc ctcaacaccactacatactattattctgtgcgagtgttcgcggggcaggagcccagtggt gtgtgggtgggctggatcacacctgactatcatcagtatgaccctcattttgacctcagc aaagtgagaaatgtgaccgtcactgtaggtgatgataaaggcaacattcatgacagtata aagcgcagtaactgctacatggtgtggggaggggagttcagcagctcccagcagacccgg gtcagtcaggaggactttataattggctgtctgattgacttggacacgggcctcatgact ttcactgcaaatgggaaagagatcaacacattttaccaggtggagccccacactaaactg ttcccagctgtctttgtccttccttccagtcagaatatgattcagtttgagttaggcaag ctcaagaacattatgccgatctcaaccgccatgttccgtagtgaacgcaagaaccctgtt ccccaatgccctcccaggctggatgtccagatgttgaccccggtcatctggagccgaatg ccaaacaatttcctggctccagagacagggcgtgttagtgagcggctgggctggatcgtg cagtgtcaggagccgctcaccatgatggctctccacatccccgaggagaacaggtgtatc gacatcctagagctgtctgaacgcatggacctgctgaagttccactaccacactctgaag ctgtacggctcagtgtgtgctctgggaaacaaccgagtggctcacgctctgtgcagccac gtggatgaatcccagctcttctacgccatcgagaacacctacctgcctggaccaatgagg agcggattctacgacctgctcatcagcatgcacctggagtctgccaagaggaaccgactg ggaaccaacaaggaattcatagttccaatgacggacaacacccgtagtatcactctgtac tcagaaaaatctcacgctttacctggagtcggcctcactacatgcctgcgtcccaaactc catttctcctcagttggttttgtgggaacagatccagacatctacacactgagtccagtt atccctttacaggtgctaaagaccaaagctttgaacatgctgattgaggcggtgcaggat ggaggtcaagccatgagagatcctgtcggaggcagcgtggagtttcattttgttccgatc ctgaagctcatcagcaccctcctcatcatgggtgtgtttgacgacgaagacgtcacgcac atcctgaagatgatcgagccgacggtcttcagtggcaagaaagcagaggagcctgctgag gagaacgccaagatgatggaggagaagaaaccacagaaagaagaagcggctaagggagag gatcgggaagcagttggcgaggaagatgaagaggaatatgaagacgatggcttgggcgaa gaggaggaggaagaagaaattgaggaagaggaagaacttgagcagacagaatctattgtg ccacatgaagaaacaatggttgagacagagccggtaaacggtgagaaaggagcagaggaa acggagaaagagattaaagaggagagtaaagaagaagaactagagcaagggcttttccag atgaagctcccagagtctgtcaaattacagatgtgtacactactgcagtatttctgtgac tgtgagctacgtcatagagttgaggccatcactgccttttcagaccaattcgtcagccag atacagttcaaccagaggcatcgatataacgaactcatgctggccttcaccatgagtgca gccgagactgctcgcaagactcgagaatttcgttctccaccacaagagcaggtcaacatg ctcatgaacttcaagaactgcgctgaagatgaagattgccctgttcccgatgaggtccgc gaagctctgctgattttccacaatgctctgttggcacactgcggtgttcatatagaagaa gaagaacaagaggccgaagtcgataattcagttcgtggacgactgctccgattgttggag aaggtcaaaacattccgggagaagaaggtagaggtggagcctgagccgcaggaggataaa aaaccaagcaccttgcaggagctgatttctcacactatgatccattgggcccaggagtca tttatccaaaaccctgagctcgtgcgtatgatgtttagcctccttcacaggcagtatgat gggctcggtgagctcatgcgtgccctccccaaagcctacaccatcaaccaagtgtcaatc aacgacaccatggacctgctcgagtgcttgggccagatccgctcactcctcattgttcag atgggcccagaagaagagaggcttatgattcaaagcatcgggaacatcatgagtaacaaa gtcttctatcagcaccctaacttgatgcgagctctgggcatgcatgaaactgtcatggag gtcatggttaatgtgctgggcggtggggactcaaaggagatcagattccctcgagtggtg acaaactgttgccgtttcctctgctatttctgtcgcatcagtcgccaaaaccagcgttcc atgtttgaccacctcagttaccttctccagaacagtggcatcggcctcggaatgcggggc tccactccattggatgtggctgcagcctcatgcatcgacaacaacgagctggcattggcc ctccaagagcaggacctggaaatggtagtgaaatatttggctggatgtggacttcagagc tgcccaatgctgctggccaaaggctaccctgacattggctggaatccttgcggtggagag aaataccttgactttcttcgttttgctgtatttgtcaatggagagagcgtagaagagaat gccaacgtggtggtacgtcttctcatccgcaggcctgagtgcttcggtccagctctgaga ggggagggtggtaatggtctactggctgcaatagaggaggccatcaaaatatcagaggac cctgcaagggatggccccagtgttaagaaagacaggcgctttcccatgtttggtggagaa gagcagcatgaagaaaacagggtgcatctgggaaatgccatcatgtccttttactctgcc ctgattgatttgctgggacgctgtgctccagagatgcacttgatccaggctggtaagggt gaagctctgaggatcagggccatcctgaggtcactggtccctcttgaggatctggtagga gtcatcagccttcctgttcagattccttcctttggcaaagacaacagcatcatagaacca aagatgtcggctagttttgtacccgatcacaaggctcccatggttctgttcctggacaga gtgtatggcattgacaaccaggatttccttctgcatgtgctggaggtgggctttctgcct gacatgagggctgctgcctctctagacacggctgcgttctgtaccacagagatggccctc gctttgaaccgctacctgtgttctgctgtgttgccgctcatcacaaagtgtgcgccactc tttgctggcagtgaccacagagccattatgatcgactccatgttgcacacaatctaccgg ctgtctcgtggacgcgccttcacaaaagctcaaagagacatcattgaagagtgcctcatg gctttgtgcaaacatctacgtccctccatgcttcaacatctgctaagaagactggtgttt gatgtgcccattctcaatgagtatgcaaagatgccgctgaagcttttgacaaatcattat gagcggtgttggaagtattattgcctccctaatggctggggcaacttcggggtatcatca gaggaggagctgcatctgacccgcaaactgttttgggggatctttgaatcattagcacac aagaaatttgatgctgagattttcaaaatttcaatgccatgcatctgcgccattgccggg gccattcctcctgactatgtcgacgccagctactcctcaaaaaccgagaaaaaggcgtcg gtcgacgcagaaggaaactttgatcctaaaccagtggagaccacaaacactatcatccct gagaggctggatcctttcatcaacaaatatgctgaatacacacacgataaatgggccttt gaaaagatccagaataactggtcgtatggcgaggtgctggatgaaaatgggaaaactcat cccatgctcagaccatacaaaaccttctcagaaaaggacaaggagatctaccgttggcca atcaaagagtcagtcaaagccatgcttgcatgggagtggaccatagataaagctagagag gaagaagagtcagagaagaagaagactgcagcacggaaaatctcacagactgctcaggcc acctatgacccaagccatggctacagtccacaacccattgagattacacacatggctctt tcaagagacctgcagtctatggcagaacaactggcagaaaactaccataacacctgggga cggaagaaaaagttagagctgcagtccaagggaggtggaacacatcctctgctggtgccc tacgacaccctgacggcaaaagaaaaggcccgagacagagagaaggctcatgagctgctc aagttcctgcagcttaatggatacgctgtcacgcggggcctgaaggacatggagtctgac atctcatccattgagaagaggtttgcgtatggattcctgcagaagctgttgaaatggatg gaaatcgcccaggagttcatcgctcatcttgaggctgtggttagcagtggacgagtggaa aagtctcctcatgagcaagaaatcaaattctttgctaagatcctgatgcctctgatcaac cagtatttcaaaaaccactgcctctactttttgtcaacgcccgcaaaagttctgggcagt ggcggccattcgtcaaataaggagaaggagatgattgcgagtatcttctgtaaaatgtcc gctctggtgagacacagagtttctctctttggaacggacgctcaagcaatcgtcaactgt cttcacattctggcacgatcattggatgcaaggacagtgatgaagtcgggcccggagatc gtgaaagcaggtcttcggtcattctttgaaagtgctgctgatgatatagagaagatggta gagaacctcaaactgggaaaagtgtccaaaggcaatcagcaagtgaaaggagtgtcccag aacattaactacacaaccatcgccctgctcccagtgctcacctctctgtttgatcacgtc gctcagcaccagtttggagatgatgtcatgttggacgatctgcagatgtcatgctaccgc atcatgtgcagcatctattccttagggactgtcaagaatccacatgtagagaggcagagg ccggctcttggagagtgcttggctcatcttgctgcagctatgccagtggcttacttagag ccccatctaaatgaatacaacgctttttctgtgtacactacaaagacccccagggagaga gccatcttgggccttcccaatgaggtccaggagttatgtccagacatcccagagctggat gttctcctgaaggagatcggggacttggcagagtccggcgctcgttatactgaaatgcct catgtgattgaaatcactctccccatgctgtgtaactacctgcctcgctggtgggagaga gggtctgagaacttccctgaattggagaaccagatctgcaccgatgtgacgtcagaacac ctgaatcagatgctcggcagcatcatgaaaatcgtagtaaacaacttgggtattgatgag gcttcttggatgaagaggttggctgtgttttcacagcccattgtcagcagagcaaagcca gaaatgctcaagtcccacttcatcccaacaatggagaagctgaagaaacgcacttcaaag gtggtggctgaagaggaccatctgcggatggaggggaaatcggagggagatgaagaagac ggtactatacgggatgagtttgctgtcctctgcagagacttgtatgccctctaccctctg cttattcgctatgtggacaacaacagggcaagatggctgacatgcccagacccagatgct gaggagctcttccgaatggttggggaggtctttattttctggtccaagtctcataacttc aagcgagaggagcagaactttgtggtgatgaatgagatcaataacatgtcattcctcacc gctgatagcaagagcaaaatgagcaagggcggggactcagagggtggagggtcggatgcc gaacgtaccaagaagaagaaacggggagatcgttactctgtgcagacttcacttattgtg gctgccttaaaaaagatgctccccataggcctgaacatgtgctctcccgctgatcaggag ctcatcaacttggccaaaatccgatactctttgagagacactgatgaagaagtaagggag ttcttgcagaacaaccttcatcttcagggcaaggtggacaacccctccatgcgctggcag atggctctatacaaagagatggcggggaaggctgaagatgccgatgcccctgaaaaagtt gtcaagagagttcaggaggtgtctgctgtcctctatcaccttgaagtgacggagcatcct ttcaaatcaaagaagatggtttggcacaaactgctgtcgaagcagagacgcagggctgtg gtcgcttgctttaggatgacaccactatacaacattcctaggcacagagcttcaaacatg ttccttgaaggctacaaacgcaactggcttcacaccgagggttactcttttgaagacagg atgatagatgacttatctaaagcgatggagcaagaggaaggagacgaagaggaggagaag gagtcaaagccggatccccttcaccagctcattctgcatttcagtcggaccgctctgaca gaaaagagtaaacttgatacagatcatctttatatggcatatgccgacattatggcaaag agttgccatatgtgtgaagaagaggaagggggagaggaaatgggggaaaatgctgaggat gagatgtcctttgaggaaaaagaaatggagaagcaaaggctgctgtaccagcaggccagg ctgcataatcgtggtgctgcagagatggtcctgcaaatgatcagtgcctgcaaaggtgag actggcacaatggtgaccacaaccctcaaactgggtatctccatcctgaatggaggaaac aatgaggttcaacagaaaatgctggagtacttaagggataagaaggatgtaggtttcttc ctgagtgtccaggcgttgatgcagacatgcagcgtcctggatctgaatgcctttgagagg cagaacaaggcagaggggctgggcatggtttcagaggagggcaccaatgagaaagtgatg gcagacgacgagttcacctgcgacctcttccgattcttgcagctgctttgtgagggtcac aataacgattttcagaactacctgcggacacagaccggcagcacaacaaccatcaacatc atcatctgtaccgtcgattacctcctccgacttcaggagtccatcagcgatttctactgg tattactccggcaaggacgtcattgatgagccaggcaaaaagaatttctctaaagctatg acagtggccaaacagattttcaacagtctgactgaatatattcagggcccctgcactggt aaccagcagtccctggctcacagcaggctgtgggatgctattgttggcttccttcatgtc tttgcccacatgatgatgaagcttgcgcaggactccagccagatcgggctgctgaaggag cttctggacctgcagaaagacatggtggtgatgttgctgtcactattagagggaaatgtg gtaaatggaacaattgcccgacagatggttgacatgttggtagaatcctccagcaacgtg gagatgatcctcaagttctttgacatgttcctcaaactgaaagacatcgtggcgtcggac gctttccgtgattacgtcacagaccctcgagggctgatctccaagaaggacttccagaag gccatggacagtcagaaacagtactccccttctgagatccagtttcttttgtcctgctca gaagcagatgagaatgacatgatccactatgaggagtacgccaaccgcttccaggaacct gccaaggacatcgggttcaacatcgccgtgctgttaaccaacctgtccgagcacgttccc catgacaccaggctgaagaacttcctggaacaagcggagagcgtgctcaactacttccgc cccttccttggccgtattgaaataatgggcgccagcagaaagatcgagcgtatctacttt gaaatcagtgaagtaaaccgcaagcagtgggagatgccgcaggtcagagagtccaaacga cagttcatcttcgacgtggtcaatgagggcggggagtccgagaagatggaaatgtttgtc aacttctgcgaagacaccatctttgagatgaatatagcctcacaaatctcagagcaggag gaagaggagaagggggaagaagacgacgaaggagatgaaggtggaggtgagggaggacag ggtgcgggggcgaacggaggaggtgacgaggacagtaacggagaggaagggcagcctgag tccagctctgcctttgcagacttcatcaacagcatgttgggcttcctcagtattttcacc ttcagaaaccttcgcagacaatatcgccgagtgagaaagatgaccatcaaagagattgtc gtggctttgtccacatttttctggacaatcttgatgagtatattacactttatttacaac gtgtgcaaaggcttcttcatgatcgtctggcaaactctgttcggaggcggcttggtggag ggggcgaaaaacatcaccgtgactgagattctagcgagcatgccggatccaacgcaggac gacgtgcatggagatggacctggggagccgaggacaggggaagaacaagacactggaggt gtaacggactctggggagactgggagtggggaggaggaagaggaggacacacaggagaaa gagggtgggagagttgcaggtgttgatgctccaggtggacttggagacatgggtgtggag tcacctgtcgaaccgccaactcccgaaggaacgccaataacaaaaaggaaaatgcctcaa gaagagcctgaggcgagccagaaaccacctgaacctgttcctgtagtggaacctccccct gaacccgaaaaggctgaggttgaaactggagagaaagccgaaaaagactccccaagcaag gaggaagaacagcgagtagagcgcaagatatctgcgaaaaaggagaagaagccgaaaagg gaaggaggttttcagatctggactgagctggaaacccaaagaaataaattcatgaactac ctctctagaaacttttacaacctgcgctttttggctctgttcctcgcatttgccctgaac ttcattctgctgttctacaaggtgtctgacacgccccctgagggtgaagagatggagggg tcagggtttgcagaggggagcggtatgtttgaaggctctgggctgtttgaaggctcggct gaagaagccgagggatctggaatgagtgacggaggagatgaggacgaggaagatgttccg ctttatttctatttagaggagagcactggctacatgcagccaacactggcctttattgct gccctgcacacagtcatttcattcatctgtatcattggctacaactgtctcaagattcca ctggttatctttaaacgggagaaagaacttgcaagaaagttggagtttgacggcctctac atcaccgagcagcctgaggatgatgacataaagggccagtgggacagactggttctgaat acaccctccttcccaaacaactattgggataagtttgtcaaacgaaaggtcctggataag tacggagacatctatggcagagaaagaatcgctgaacttctgggtgtggatttagcctcc ctggatgtgagccaacagcatgagaagaaacaggaggaaccagacagctccatgttttca tgggtgacgtccattgacatcaagtaccagatctggaagtttggcgtcattttcacagac ggtaccttcctttatctgtgttggtacctgatcatgtccctgctcggacactacaacaac ttcttctacgcctgtcacttgctggacatcgccatgggtgtcaagactcttcgcactatc ctgtcctcagtcacacacaacggcaaacagctcatgatgacggtgggcttgttggcggtg gtggtgtacctttacacggtggtcgcgttcaatttcttccgcaagttttacaacaagagc gaggatgaagatgaacccgatatgaaatgtgatgacatgatgacttgctatctgttccac atgtacgtcggtgtgcgtgctggtggaggcattggagatgaaatcgaggatcccgctgga gatgaatacgagctttatcgagtggtctttgacattaccttcttcttctttgtcatcgtt attcttctggccatcattcagggtctgatcattgatgcctttggagaactccgagaccaa caggagcaggtcaaggaagacatggagacgaaatgcttcatatgtgggattggaagcgac tactttgatacgacgccacacggctttgagacgcacacgtttgatgaacacaacctggcc aattacatgttctttttaatgtacctcatcaacaaagatgaaacggagcacactggacag gagtcctatgtgtggaaaatgtaccaggagcgtgcgtgggactttttccccgctggagac tgttttagaaagcaatatgaggatcagctatcataa

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