Legionella pneumophila 2300/99 Alcoy (serogroup 1): lpa_02196
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Entry
lpa_02196 CDS
T01232
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
lpa
Legionella pneumophila 2300/99 Alcoy (serogroup 1)
Pathway
lpa00010
Glycolysis / Gluconeogenesis
lpa00020
Citrate cycle (TCA cycle)
lpa00620
Pyruvate metabolism
lpa00785
Lipoic acid metabolism
lpa01100
Metabolic pathways
lpa01110
Biosynthesis of secondary metabolites
lpa01120
Microbial metabolism in diverse environments
lpa01200
Carbon metabolism
lpa01210
2-Oxocarboxylic acid metabolism
Module
lpa_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
lpa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
lpa_02196 (aceE)
00020 Citrate cycle (TCA cycle)
lpa_02196 (aceE)
00620 Pyruvate metabolism
lpa_02196 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
lpa_02196 (aceE)
Enzymes [BR:
lpa01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
lpa_02196 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ADG24834
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Position
complement(1725288..1727951)
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AA seq
887 aa
AA seq
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MTNETNLDLDPIETREWLDALQAVLFNDGPERTAFLLQQLLNKANAEGVKLTSSINTPYR
NTIKPHEEKQMPPDEGIGKRINALIRWNAVAMVLRAGKYAPELGGHIASYASASTLYETG
FNYFFKGQKGENGGDLLYIQGHSAPGIYARAFLEGRLTEKQLEKFRQEVEVDGLSSYPHP
WLMNDFWQFPTVSMGLGPLQAIYQARFLKYLENRGLIKAEGRKVWAFLGDGEMDEPESVG
ALSIAAREKLDNLIFVVNCNLQRLDGPVRGNGKIIQELEGLFRGAGWNVIKVIWGGRWDP
LFARDNQGWLQKRMEECLDGDYQSYKANDGSYVRQHFFNQYPELKKMVENMSDEEIWRLN
RGGHDPQKVYAAYARAVEHKGTPTVILAKTIKGYGMGAAGEGQNITHQQKKMTIDQLKAF
RDRFNIPISDDKIADIPFYKPDDDSPEIKYIKKQREALGGYLPHRSTEVEQLKIPDLGEF
SSITKGLGDREISTTMAFVRILSALLKNKDINSRIVPIVPDECRTFGMEGLFRQIGIYSP
VGQLYTPVDHEQVMYYREAVDGQILEEGINEAGAFCSWIAAATSYSSNKLAMIPFYIYYS
MFGFQRIGDLAWAAGDMQARGFLLGGTAGRTTLAGEGLQHQDGHSHVLASTIPNCISYDP
TYAYELAVIIQNGLHRMYEKQENVFYYITIMNENYSHPDMPAGVEEGIIKGMYLLKENKK
KSKNHVQLMGCGTILREVIKAAEMLEEDFSITSDIWSVTSFNELRKEGLAVERYNNMHPQ
NKPQESYVTSQLKGRRGPVIASTDYMRIYADQIRPFVPNRYITLGTDGYGRSDTRTQLRH
FFEVDAKFIVLAALNALVAEGSLDKAKIVDAMKRYNINQDKLDPMTH
NT seq
2664 nt
NT seq
+upstream
nt +downstream
nt
atgaccaatgaaacaaatttagatctggatccaatagaaacgcgtgaatggctggatgcc
ctacaagctgtactctttaatgatggtcctgagcgtactgcattccttttacagcagctt
cttaataaagcgaacgccgagggggttaaactaaccagctcaattaatactccctacaga
aacactataaaacctcacgaagaaaaacaaatgcctcccgatgagggaattggaaagcgc
atcaatgcattaattagatggaacgctgttgcaatggtacttagggcaggtaaatacgcg
ccagagcttggcggccatatcgcttcttatgcatctgcatcaacgttatatgaaactgga
tttaactatttttttaagggtcaaaaaggcgaaaacggaggggacttgctttatattcaa
ggccactcggctccaggcatttatgccagagcatttcttgaaggccgattaacagagaaa
caacttgaaaaattccggcaagaagtagaggtagatggtttatcttcctacccacaccct
tggctaatgaacgatttttggcaatttcccaccgtatccatgggtttgggccctctacaa
gcaatatatcaagctcgctttctaaaatatcttgagaaccggggactgatcaaagctgag
ggtaggaaagtatgggcatttttgggtgatggcgagatggatgagcctgaatcagtcggg
gcactcagtatcgcagcacgagaaaagctggataatctcatttttgtagttaattgcaat
ttacaaagacttgatgggcctgtgcgtggtaacggtaaaatcattcaagaacttgaaggc
ctatttcgaggagctggatggaacgttattaaggtcatctggggaggccgttgggatcca
ttatttgcccgtgataatcaaggctggctacagaaaagaatggaagaatgtctggatgga
gattatcaatcttacaaagcgaacgatggatcgtatgtaagacaacatttctttaatcaa
tatccagaattaaagaaaatggttgaaaatatgtctgatgaggaaatttggcgattaaat
cgtggtggccatgatcctcaaaaagtgtatgcagcttatgccagagcagttgaacacaag
ggaactccaacagttatccttgcaaaaaccatcaagggctacgggatgggtgcggctggt
gagggacaaaacattactcatcaacagaaaaaaatgaccatagatcaactaaaagctttc
agagatcgatttaatattccaatcagcgatgacaaaattgctgatattcctttctataaa
cctgatgacgacagtcctgaaatcaagtatataaaaaagcaaagggaagccttgggcggt
tatttgccccaccgttcaactgaagtagaacagttaaaaatacctgatttaggagagttt
tccagtattaccaagggattaggagatagagaaatctcgactactatggcatttgtgcga
attctttcagctctactcaaaaataaagacattaattccagaatagttcccatagtacca
gatgaatgcagaacattcggtatggagggattattcagacaaattggaatttattctccc
gtaggtcaactttatactcctgtagatcatgaacaagtgatgtattaccgagaagcagtt
gacgggcagattcttgaagaaggtattaatgaagctggggcgttttgttcatggattgct
gccgcaacctcttacagttcaaataagctggcaatgattccattttacatttattactct
atgtttggtttccaacgcattggtgatttagcatgggcggcaggagacatgcaagcgaga
ggatttctgctcggtggaaccgctggacgaacaacgctggcaggagaaggattgcaacac
caagatggacatagtcatgttttagcatcaacaatacctaattgtatttcttatgatccc
acatacgcctatgaattagcagttatcatccaaaatggattgcaccgtatgtatgaaaaa
caggaaaacgtgttttattacattactattatgaatgaaaactactctcatcccgatatg
cctgcaggggtagaggaaggtattatcaaaggaatgtatctcttaaaagaaaataagaaa
aaatcaaaaaaccatgtccaactaatgggatgcggtactattttgcgtgaagttatcaaa
gccgcagagatgctggaagaggatttttcaattacatcggatatctggagtgtaaccagc
ttcaatgagctacgtaaagaaggtttggctgtagagcgatacaataacatgcacccccaa
aataagcctcaggaaagttatgtgacatctcaattaaaaggacgtcgtggacctgttata
gcctcaactgactatatgcgtatttatgcagatcagatcaggccttttgttcctaatcgc
tatattaccctaggtacagacggttacggcagaagtgatacccgtacacaactacgtcat
ttctttgaagttgatgcaaaatttatagtgttggcagcattaaatgcacttgtagctgaa
ggtagccttgacaaagcaaaaattgtcgatgccatgaaacgttacaatattaatcaagac
aaattggatccaatgacccattag
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