Legionella pneumophila subsp. pneumophila Lorraine (serogroup 1): LPO_1517
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Entry
LPO_1517 CDS
T02175
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase, decarboxylase component E1, thiamin-binding
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
lpo
Legionella pneumophila subsp. pneumophila Lorraine (serogroup 1)
Pathway
lpo00010
Glycolysis / Gluconeogenesis
lpo00020
Citrate cycle (TCA cycle)
lpo00620
Pyruvate metabolism
lpo00785
Lipoic acid metabolism
lpo01100
Metabolic pathways
lpo01110
Biosynthesis of secondary metabolites
lpo01120
Microbial metabolism in diverse environments
lpo01200
Carbon metabolism
lpo01210
2-Oxocarboxylic acid metabolism
Module
lpo_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
lpo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
LPO_1517 (aceE)
00020 Citrate cycle (TCA cycle)
LPO_1517 (aceE)
00620 Pyruvate metabolism
LPO_1517 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LPO_1517 (aceE)
Enzymes [BR:
lpo01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
LPO_1517 (aceE)
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Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
CCD05548
UniProt:
A0AAV2UW22
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Position
complement(1551746..1554409)
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AA seq
887 aa
AA seq
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MTNETNLDLDPIETREWLDALQAVLFNDGPERTAFLLQQLLNKANAEGVKLTSSINTPYR
NTIKPHEEKQMPPDEGIGKRINALIRWNAVAMVLRAGKYAPELGGHIASYASASTLYETG
FNYFFKGQKGENGGDLLYIQGHSAPGIYARAFLEGRLTEKQLEKFRQEVEVDGLSSYPHP
WLMNDFWQFPTVSMGLGPLQAIYQARFLKYLENRGLIKAEGRKVWAFLGDGEMDEPESVG
ALSIAAREKLDNLIFVVNCNLQRLDGPVRGNGKIIQELEGLFRGAGWNVIKVIWGGRWDP
LFARDNQGWLQKRMEECLDGDYQSYKANDGSYVRQHFFNQYPELKKMVENMSDEEIWRLN
RGGHDPQKVYAAYARAVEHKGTPTVILAKTIKGYGMGAAGEGQNITHQQKKMTIDQLKAF
RDRFNIPISDDKIADIPFYKPDDDSPEIKYIKKQREALGGYLPHRSTEVEQLKIPDLGEF
SSITKGLGDREISTTMAFVRILSALLKNKDINSRIVPIVPDECRTFGMEGLFRQIGIYSP
VGQLYTPVDHEQVMYYREAVDGQILEEGINEAGAFCSWIAAATSYSSNKLAMIPFYIYYS
MFGFQRIGDLAWAAGDMQARGFLLGGTAGRTTLAGEGLQHQDGHSHVLASTIPNCISYDP
TYAYELAVIIQNGLHRMYEKQENVFYYITIMNENYSHPDMPAGVEEGIIKGMYLLKENKK
KSKNHVQLMGCGTILREVIKAAEMLEEDFSITSDIWSVTSFNELRKEGLAVERYNNMHPQ
NKPQESYVTSQLKGRRGPVIASTDYMRIYADQIRPFVPNRYITLGTDGYGRSDTRTQLRH
FFEVDAKFIVLAALNALVAEGSLDKAKIVDAMKRYNINQDKLDPMTH
NT seq
2664 nt
NT seq
+upstream
nt +downstream
nt
atgaccaatgaaacaaatttagatctggatccaatagaaacgcgtgaatggctggatgcc
ctacaagctgtactctttaatgatggtcctgagcgtactgcattcctgttgcagcagctt
cttaataaagcgaacgccgagggggttaaactaaccagctcaattaatactccctacaga
aacactataaaacctcacgaagaaaaacaaatgccccccgatgagggaattggaaagcgc
atcaatgcattaattagatggaacgctgttgcaatggtacttagggcaggtaaatacgcg
ccagagcttggcggccatatcgcttcttatgcatctgcatcaacgctatatgaaactgga
tttaactatttttttaagggacaaaaaggtgaaaacggaggggacttgctttatattcaa
ggtcactcggctccaggcatttatgccagagcatttcttgagggccgattaacagagaaa
caacttgaaaaattccggcaagaagtagaggtagatggcttgtcttcctacccacaccct
tggctaatgaacgatttttggcaatttcccactgtatccatgggcttaggccctttgcaa
gctatctatcaagctcgctttctaaaatatcttgagaaccggggactgatcaaagctgag
ggtagaaaagtatgggcatttttgggtgatggtgagatggatgagcctgaatcagtcggg
gcactcagtatcgcagcacgagaaaagctggataatctcatttttgtagtcaattgcaat
ttacaaagacttgatgggcctgtgcgtggtaacggtaaaatcattcaagaacttgaaggc
ctatttcgaggagctggatggaacgttattaaggtcatctggggaggccgttgggatcca
ttatttgcccgtgataatcaaggctggctacagaaaaggatggaagaatgtctggatgga
gattatcaatcttacaaagcgaacgatggatcgtatgtaagacaacatttctttaatcaa
tatccagaattaaagaaaatggttgaaaatatgtctgatgaggaaatttggcgattaaat
cgtggtggccatgatcctcaaaaagtatatgcagcttatgccagagcggttgaacacaag
ggaactccaacagttatccttgcaaaaaccatcaagggctacgggatgggagctgctggt
gagggacaaaacattactcatcaacagaaaaaaatgaccatagatcaactaaaagctttc
agagatcgatttaatattccaatcagcgatgacaaaattgctgatattcctttctataaa
cctgatgacgacagtcccgaaatcaaatatataaaaaagcaaagggaagccttgggcggt
tatttgccccaccgttcaactgaagtagaacagttaaaaatacctgatttaggagagttt
tccagtattaccaagggattaggagatagagaaatatcgactactatggcatttgtgcga
attctttcagctctactcaaaaataaagacattaattccagaatagttcccatagtacca
gatgaatgcagaacattcggtatggagggattattcagacaaattggaatttattctccc
gtaggtcaactttatactcccgtagatcatgaacaagtgatgtattaccgagaagcagtt
gacgggcagattcttgaagaaggtattaatgaagctggggcgttttgttcatggattgct
gccgcaacctcttacagttcaaataagctggcaatgattccattttacatttattactct
atgtttggtttccaacgcattggtgatttagcatgggcggcaggagatatgcaagcgaga
ggatttctgctcggtggaaccgctggacgaacaacgttggcaggagagggattgcaacac
caagatggacatagtcatgtcttagcatcaacaatacctaattgtatttcttatgatccc
acatacgcctatgaattagcagttatcatccaaaatggattgcaccgtatgtatgaaaaa
caggaaaacgtgttttattacattactattatgaatgaaaactactctcatcccgatatg
cctgcaggagtagaggaaggtattatcaaaggaatgtatctcttaaaagaaaataagaaa
aaatcaaaaaaccatgtccaactaatgggatgcggtactattttgcgtgaagttatcaaa
gccgcagagatgttggaagaggatttttcaattacatcggatatctggagtgtaaccagc
ttcaatgagttacgtaaagaaggtttggccgtagagcgatacaataacatgcacccccaa
aataagcctcaggaaagttatgtgacatctcaattaaaaggacgtcgtggacctgttatt
gcctcaactgactatatgcgtatttatgcagatcagatcaggccttttgttcctaatcgc
tatattaccctaggtacagacggttacggcagaagtgatacccgtacacaactacgtcat
ttctttgaagttgatgcaaaatttatagtgttggcggcattaaatgcacttgtagctgaa
ggtagtcttgataaagcaaaaattgtcgatgccatgaaacgttacaatattaatcaagat
aaattggatccaatgacccattag
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