Lynx rufus (bobcat): 124506146
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Entry
124506146 CDS
T08475
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
lruf
Lynx rufus (bobcat)
Pathway
lruf04010
MAPK signaling pathway
lruf04020
Calcium signaling pathway
lruf04151
PI3K-Akt signaling pathway
lruf05200
Pathways in cancer
lruf05216
Thyroid cancer
lruf05223
Non-small cell lung cancer
lruf05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
lruf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
124506146
04020 Calcium signaling pathway
124506146
04151 PI3K-Akt signaling pathway
124506146
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
124506146
05230 Central carbon metabolism in cancer
124506146
09162 Cancer: specific types
05216 Thyroid cancer
124506146
05223 Non-small cell lung cancer
124506146
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lruf01001
]
124506146
Enzymes [BR:
lruf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
124506146
Protein kinases [BR:
lruf01001
]
Receptor tyrosine kinases (RTK)
RET family
124506146
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD1
RET_CLD4
RET_CLD3
Pkinase
RET_CRD
Cadherin
RIO1
Pkinase_fungal
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
124506146
NCBI-ProteinID:
XP_046928121
LinkDB
All DBs
Position
Unknown
AA seq
1180 aa
AA seq
DB search
MARAGQGHGELAKSLLAELDSSPLLMGKLAELLGPGLACSFELAGDNLPRHRGAKAVDGH
AVPGSDPPSEPAFRDVAMLALGQDAAMAPLGLYFARDAYWEKLYVDQPAGMPLLYVHALR
DMPEEVPTFRLGQHLYGIAYRARLHENDWIRIEEDTGLLYLNRSLDHSTWDKLSIRNGGF
PVLTIYLQVFLSPTSLREGECQWPGCARVYFSFVNTSFPACGSLKPRELCFPETGVSFRI
RENRPPGTFHQFRLLPVQFLCPNISVAYRLLEGENLPFHCAPDSLEVSTRWPLDRELREK
YELVAACTVRVGARKEEVVMVPFPVTVYDEDDSAPTFLGGIDTASAVVEFKRKEGTVVAK
IRVFDADVVPASGELLKRYTNTLLSGDAWVLQTFRIEHSPNETLAQANGSFVRATVHDYR
LVLNRSLPISENRSLQLTVLVNDSDFQGPGEGTLFLHFNVSVLPVSLHLPSTYTFTVSRR
ARRFAQIGKVCVENCQEFSGIHVQYRLQLSSTNCSVLGVVTSAEDTTGNLFVNDTEALQR
PDCSQLRYTVVAADRPTRKQTQALLVVTVEGTYVAEEPGCPLSCAVSKRRPECEECGGLG
SLTGRCEWRQGDGKGITRNFSTCSPSIKTCPDGHCDAVESRNVNICPQDCLRGGSIIGGH
EPGERWGIKAGFGICNCFPEEKKCFCEPEDSQEPLCDELCRTVIAAAVLFSFVVSMLLST
FCIHRYHKNAHKPPIASAEMTFRRPAQAFPVSYSSSGARRPSMDSMENQVSVDAFKIPED
PKWEFPRKNLVLGKTLGEGEFGKVVKATAFRLKGKAGYTTVAVKMLKENASPSELRDLLS
EFNLLKQVNHPHVIKLYGACSQDGPLFLIVEYAKYGSLRGFLRESRKAGPGYVGSGGSRS
SSYLDNPEERALTMGDLISFAWQISRGMRYLAEMKLVHRDLAARNVLVAEGRKMKISDFG
LSRDVYEEDSYVKRSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPG
IPPERLFNLLKTGYRMERPDNCSEEMYGLMLQCWKQEPDKRPVFADISKDLEKMMVKNRD
YLDLAASTPSDSLLYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPEESP
VPLTRADGTNTVCPRYANDSVYANWMVSPSAAQLMDAFDS
NT seq
3543 nt
NT seq
+upstream
nt +downstream
nt
atggccagggctggccagggccatggagagctggcgaagagcctgctggcggagctggac
agcagcccactgctcatggggaagttggctgagttgcttgggccgggactggcctgcagc
ttcgagctggctggagacaatcttccaaggcacaggggagccaaggctgtggacggccat
gctgtgcccggctctgatcccccttctgagcctgccttccgggacgtggccatgctggcg
ctggggcaggatgctgccatggctccgctgggactctacttcgccagggatgcttactgg
gagaaactctacgtggaccagccagctggcatgcccctgctctacgtccatgccctgcgg
gacatgccggaggaggtgcccaccttccgcctgggccagcacctctacggcatcgcctac
cgtgcaaggctgcatgagaacgactggattcgcatcgaggaggacaccggccttctctac
cttaaccggagcctggatcacagcacctgggacaagctcagcatccgcaatggcggcttc
cctgtgctcaccatctacctccaggtcttcctgtcacctacatccctgcgcgagggcgag
tgccaatggcccggctgtgcccgtgtgtacttctcctttgtcaacacctccttcccggct
tgtggttccctcaaaccccgggagctctgctttcctgagacaggtgtctccttccgcatc
agagagaacaggcctcctggcactttccaccagttccgcctgctgcctgtgcagttcctc
tgccccaacatcagtgtggcctacaggctcctagaaggtgagaacctgcccttccactgc
gccccggacagcctggaggtgagcacgcgctggcccctggatcgcgagctgcgggagaag
tacgagctggtggctgcttgcacggtgcgcgtcggcgcacgcaaggaggaggtggtgatg
gtgcccttccccgtgaccgtgtatgatgaggacgactcggcgcccaccttcctcgggggc
atcgacaccgccagcgctgtggtggagttcaagaggaaggagggcactgtggtggccaaa
atacgtgtcttcgatgcagacgtggtgccagcatccggggagctcctgaagcgatacaca
aacacactactctctggggatgcctgggtcctccagacattccgtatcgagcactccccc
aacgagaccttggcccaggccaacggcagctttgtgcgggcaactgtgcatgactacagg
ctggttctcaaccggagcctccccatctcggagaaccgctccctgcagctgaccgtgctg
gtcaatgactcggacttccagggccccggggagggcaccctcttcctccacttcaacgtg
tccgtgctgcctgtcagcttgcacttgcccagcacctacaccttcactgtgagcaggcgg
gcccgccgctttgcccagattgggaaagtctgtgtggaaaactgccaggagttcagcggc
atccacgtgcagtacaggctgcagctctccagcaccaactgcagtgtcctgggggtggtc
acctcagccgaggacaccacagggaaccttttcgtgaacgacacagaagccctgcagcgg
cccgattgctctcaactccggtacacggtagtggctgccgaccggccaacccgcaagcag
acccaggccctgctggttgtcaccgtggaggggacatatgtggctgaggagccaggctgc
cccctgtcctgtgcagtcagcaagagacgccctgaatgtgaggagtgcggtggcctgggc
tctctgacgggcaggtgcgagtggagacagggagatggcaaaggaatcaccaggaacttc
tccacctgctcccccagcatcaagacctgccccgacggccactgtgatgccgtggagagc
agaaatgtcaacatctgcccccaggactgcctccggggcggcagcatcattggtgggcat
gagccaggggagcgctgggggattaaagctggcttcggtatctgcaactgtttcccagag
gagaagaagtgcttctgcgaacctgaagacagccaggagccgctgtgtgacgagctctgc
cgcacggtgatcgcggccgctgtgctcttctccttcgtcgtctccatgctgctctccacc
ttctgcatccaccgctaccacaagaacgcccacaagccacccattgcctctgctgagatg
accttccgccggcctgcccaggccttcccggtcagctactcctcgtccggcgcccgccgg
ccctctatggactccatggagaaccaggtctctgtggacgccttcaagatcccggaggat
ccaaagtgggaattccctcgaaagaacttggttcttgggaaaaccctgggagaaggcgaa
tttggaaaagtggttaaggcgacagccttccggctgaaaggcaaagcagggtacacaacc
gtggccgtgaagatgctgaaagagaacgcttccccaagtgagctgcgggacctgctgtca
gagttcaacctcctgaagcaggtcaaccacccacatgtcatcaagctgtacggggcctgc
agccaggacggcccgctcttcctcattgtggagtatgccaagtacggttccctgcggggc
ttcctccgagagagccgcaaggcggggcccggctacgtgggcagcggaggcagccgcagc
tccagctacctggacaaccccgaggagcgggccctgaccatgggcgacctcatctccttc
gcctggcagatctctcgggggatgcggtacctggctgagatgaagcttgtccatcgggac
ttggcagccagaaatgtcctggtagctgaggggcggaagatgaagatttcggattttggc
ctgtcccgagacgtttatgaagaggattcctatgtgaagaggagcaagggtcggattcca
gtcaaatggatggcaattgagtctctttttgatcatatctacaccacccaaagtgatgtg
tggtcctttggtgtcctgctgtgggagattgtgactctggggggcaacccctaccctggg
atccctccggagcggcttttcaacctcctgaagacaggctaccggatggagaggcctgac
aactgcagtgaggagatgtacggtctcatgctgcagtgttggaagcaggaaccagacaag
aggccagtgtttgctgacatcagcaaagacctggaaaagatgatggttaagaacagagac
tacttggacctggctgcctccaccccatccgactccctgctttatgacgatggcctctcg
gaggaggagacgcccctggtggactgtaataatgctcccctccctcgagccctcccctcc
acgtggattgaaaacaaactctatggcatgtcagacccgaactggcctgaagagagtcct
gtaccactcacgagagctgatggcactaacactgtgtgtccaagatatgcaaatgatagt
gtatatgctaactggatggtttcaccctcagcggcacaattaatggacgcatttgatagt
taa
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integrated database retrieval system
