Lynx rufus (bobcat): 124507481 Help Entry 124507481         CDS       T08475                                  Name (RefSeq) adenylate cyclase type 8   KO K08048   adenylate cyclase 8 [EC:4.6.1.1] Organism lruf  Lynx rufus (bobcat) Pathway lruf00230   Purine metabolism lruf01100   Metabolic pathways lruf01522   Endocrine resistance lruf04015   Rap1 signaling pathway lruf04020   Calcium signaling pathway lruf04022   cGMP-PKG signaling pathway lruf04024   cAMP signaling pathway lruf04062   Chemokine signaling pathway lruf04072   Phospholipase D signaling pathway lruf04081   Hormone signaling lruf04082   Neuroactive ligand signaling lruf04114   Oocyte meiosis lruf04211   Longevity regulating pathway lruf04213   Longevity regulating pathway - multiple species lruf04261   Adrenergic signaling in cardiomyocytes lruf04270   Vascular smooth muscle contraction lruf04371   Apelin signaling pathway lruf04540   Gap junction lruf04611   Platelet activation lruf04713   Circadian entrainment lruf04714   Thermogenesis lruf04720   Long-term potentiation lruf04723   Retrograde endocannabinoid signaling lruf04724   Glutamatergic synapse lruf04725   Cholinergic synapse lruf04727   GABAergic synapse lruf04742   Taste transduction lruf04750   Inflammatory mediator regulation of TRP channels lruf04911   Insulin secretion lruf04912   GnRH signaling pathway lruf04913   Ovarian steroidogenesis lruf04914   Progesterone-mediated oocyte maturation lruf04915   Estrogen signaling pathway lruf04916   Melanogenesis lruf04918   Thyroid hormone synthesis lruf04921   Oxytocin signaling pathway lruf04923   Regulation of lipolysis in adipocytes lruf04925   Aldosterone synthesis and secretion lruf04926   Relaxin signaling pathway lruf04927   Cortisol synthesis and secretion lruf04928   Parathyroid hormone synthesis, secretion and action lruf04934   Cushing syndrome lruf04935   Growth hormone synthesis, secretion and action lruf04970   Salivary secretion lruf04971   Gastric acid secretion lruf04972   Pancreatic secretion lruf04976   Bile secretion lruf05032   Morphine addiction lruf05163   Human cytomegalovirus infection lruf05166   Human T-cell leukemia virus 1 infection lruf05200   Pathways in cancer lruf05207   Chemical carcinogenesis - receptor activation lruf05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lruf00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     124507481  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     124507481    04371 Apelin signaling pathway     124507481    04020 Calcium signaling pathway     124507481    04072 Phospholipase D signaling pathway     124507481    04024 cAMP signaling pathway     124507481    04022 cGMP-PKG signaling pathway     124507481   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     124507481    04081 Hormone signaling     124507481  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     124507481   09144 Cellular community - eukaryotes    04540 Gap junction     124507481  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     124507481    04062 Chemokine signaling pathway     124507481   09152 Endocrine system    04911 Insulin secretion     124507481    04923 Regulation of lipolysis in adipocytes     124507481    04912 GnRH signaling pathway     124507481    04913 Ovarian steroidogenesis     124507481    04915 Estrogen signaling pathway     124507481    04914 Progesterone-mediated oocyte maturation     124507481    04921 Oxytocin signaling pathway     124507481    04926 Relaxin signaling pathway     124507481    04935 Growth hormone synthesis, secretion and action     124507481    04918 Thyroid hormone synthesis     124507481    04928 Parathyroid hormone synthesis, secretion and action     124507481    04916 Melanogenesis     124507481    04925 Aldosterone synthesis and secretion     124507481    04927 Cortisol synthesis and secretion     124507481   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     124507481    04270 Vascular smooth muscle contraction     124507481   09154 Digestive system    04970 Salivary secretion     124507481    04971 Gastric acid secretion     124507481    04972 Pancreatic secretion     124507481    04976 Bile secretion     124507481   09156 Nervous system    04724 Glutamatergic synapse     124507481    04727 GABAergic synapse     124507481    04725 Cholinergic synapse     124507481    04720 Long-term potentiation     124507481    04723 Retrograde endocannabinoid signaling     124507481   09157 Sensory system    04742 Taste transduction     124507481    04750 Inflammatory mediator regulation of TRP channels     124507481   09149 Aging    04211 Longevity regulating pathway     124507481    04213 Longevity regulating pathway - multiple species     124507481   09159 Environmental adaptation    04713 Circadian entrainment     124507481    04714 Thermogenesis     124507481  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     124507481    05207 Chemical carcinogenesis - receptor activation     124507481   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     124507481    05163 Human cytomegalovirus infection     124507481   09165 Substance dependence    05032 Morphine addiction     124507481   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     124507481   09167 Endocrine and metabolic disease    04934 Cushing syndrome     124507481   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     124507481 Enzymes [BR:lruf01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      124507481 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom TBK1_ULD Motif Other DBs NCBI-GeneID:  124507481 NCBI-ProteinID:  XP_046929772 LinkDB All DBs Position Unknown AA seq 1251 aa AA seqDB search MELSDVRCLSGSEELYTIHPTPPAGDGGSGSRPQRLLWQTAVRHITEQRFIHGHRGSGGG SGSRGSGKASDAAGGGPNHHAAQLSGDSALPLYSLGPGERAHSSGGTKVFPERSGSGSGS GSGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRR KSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSH TYLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGT SLLQVVVQVAIPRLAVISINQVMAQAVLFMCMNTAGTFISYLSDRAQRQAFLETRRCVEA RLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFAD VKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHA HCCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANK LESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLTLPE DIVKESVSFSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALH VQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCA FIVLLFITAIQSLLPSSRVMPMAIQFSILIMLHSALVLITTAEDYKCLPLVLRKTCCWIN ETYLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSCPEYFVFT GVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETVYAGLFLRYDNLNHSGEDFLGTKE ASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHV ARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFD ELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINK HSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLI LKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGL VQSLNRQRQKQLLNENINTGIKGHYNRRTLLTPSGPEPGAQAEGADKSDSP NT seq 3756 nt NT seq  +upstreamnt  +downstreamnt atggagctctccgatgtgcgctgcctgagcggcagcgaggaactctacaccatccacccg acgcccccggccggcgacggcgggagcggctcccggccgcagcggctgctgtggcagacg gcggtgaggcacatcaccgagcagcgcttcattcacgggcaccggggcagcggcggcggc agcgggagtagaggctccggcaaagcctcggacgctgcaggcggcggccccaaccaccac gcggcgcagctgtccggggactcggcgctgcccctctactcgctgggccccggggagaga gcgcacagctccggtggcaccaaagtcttcccggaacgcagcggcagcggcagcggcagc ggcagcgggggcgggggcgatctgggcttcctgcacctggactgcgccccgagcaactcg gatttcttcctcaatgggggctatagctaccgaggggtcattttccccactctgcgcaac tccttcaagtccagggatctggagcgcctctaccagcgctatttcctgggccagaggcgc aaatccgaggtggtgatgaacgtgctggacgtgctgaccaaactcaccctcttggtcctc cacctgagcctggcctcggcccccatggacccgctcaagggcattctcctgggcttcttc actggcatcgaggtggtgatctgcgcgctcgtggtggtcaggaaggacaccacctcgcac acgtacctgcagtacagcggcgtggtcacttgggtggccatgaccacccagatcttggca gcaggcctcggctacgggcttctgggtgatggcatcggctacgtcctcttcacgctgttc gccacctacagcatgctgccgctgccgctcacctgggccatcctggccggcctgggcacc tcgctgctgcaggtggtcgtgcaggtggccattccccggctggcggtcatctccatcaac caggtgatggcccaggcagtgctgttcatgtgtatgaacacggctggaaccttcatcagt tacctgtcagaccgggcccagcgccaagccttcctggagacacggaggtgtgtggaggcc aggctgcgcctggagacggaaaaccaaagacaggagcggctcgtgctctctgtgcttccc cggtttgtcgtcctggaaatgatcaatgacatgaccaatgttgaagacgagcacctgcag caccaattccatcggatctacatccaccgctatgagaatgtcagtattctttttgcagat gtgaaaggatttaccaacctctccacaaccttgtctgcccaggagctggtcaggatgctc aacgagctctttgccagatttgatcgactggcccacgagcatcactgccttcgcattaaa atcctgggggactgttactactgtgtttcagggcttccagagccccgccaggaccacgcc cactgctgcgttgaaatgggcctcagcatgatcaaaaccatcaggtatgtgaggtcaagg acgaagcatgatgttgacatgcggatcggaatccactcgggctcggtgctgtgtggcgtg ttgggtctgaggaagtggcagtttgatgtctggtcttgggacgtggacatcgcgaacaaa cttgagtctggaggaatccctgggaggattcacatttccaaagccacgctggactgcctc aacggtgactataatgtggaagagggtcatggtaaagagagaaacgaattcttgaggaag cataacatagagacctatttgattaagcagcctgaggagagcctactgactttgcccgaa gacattgtcaaggagtcggtgagcttctcagacaggagaaacagtggggcgacattcaca gaaggatcctggagccccgaactgccctttgataacatagtggggaaacagaacactctg gctgccctaacaagaaattcaataaatctacttccaaaccatcttgcacaagctttgcat gtccagtctgggcctgaggaaattaacaagagaatagaacataccatcgacttgcggagt ggcgataaattgagaagagagcatatcaagccattctcactgatgtttaaagactccagc ctggagcacaagtattctcaaatgagggatgaagtattcaagtcaaacttggtctgtgca tttatcgttctcctatttatcacggcaatccaaagtttgcttccttcttcaagggtgatg ccaatggccatccagttttccatcctgatcatgctgcactcggctctggtcctcatcacc acggcagaagattacaagtgtttgcctctcgtcctccggaaaacttgctgttggattaac gagacctacttagcccggaacgtcatcatctttgcatccatcttgattaacttcctgggc gccatcttgaatatcctgtggtgtgattttgacaagtcgatacccttgaagaacctgact ttcaattcctcagctgtgtttacagatatctgctcctgcccagagtacttcgtcttcact ggggtgttggccatggtgacctgtgcggttttcctccgcctgaactctgtcctgaagctg gccgtgctgctgattatgattgccatctacgctctgctgactgagaccgtctacgcgggc ctcttcctgcgctatgacaacctaaaccacagcggagaagacttcctggggaccaaggag gcgtcactgctgctgatggccatgttcctccttgccgtgttctaccacggacagcagctg gagtacacggcccgcctggacttcctttggcgagtgcaggccaaagaggagatcaacgag atgaaggagctcagggagcacaatgagaacatgctccggaacattctacccagccacgtg gcccgccacttcctggagaaagaccgagacaacgaggagctgtattcccaatcttatgat gccgtcggggtgatgtttgcctccatcccggggtttgcagacttttactctcagactgag atgaataaccaaggggtagaatgcctgcgtctgttgaatgagatcattgctgacttcgat gagctgctaggcgaagaccggtttcaggacattgaaaagattaagaccatcggcagcacc tacatggccgtgtcgggcctgtcacctgaaaaacagcaatgtgaagacaagtggggacat ctgtgtgccctggccgacttctccctcgccctgacggaaagcatacaggagatcaacaaa cattccttcaacaatttcgaactccggattggcatcagtcacggctccgtggtagctggg gtcatcggcgctaagaagccacaatatgacatttggggcaaaactgtgaacctggcgagc cgaatggacagcacaggggtcagcggcaggatccaagtccccgaggagacctatctcatc ctgaaggaccagggctttgccttcgactaccgaggggagatctacgtgaagggcatcagt gagcaggaagggaaaatcaaaacgtactttctcctgggaagagtccaacccaacccgttc atcctgcccccgagaagactgcccgggcagtactcactggccgcggtcgtcctgggcctt gtccagtccctcaacaggcaaaggcagaagcagttgctcaatgagaacatcaacacaggg atcaagggccactacaaccggcggactttgctgacacccagtgggccagagcccggggcc caggctgagggcgccgacaagtccgattcgccatga

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