Lynx rufus (bobcat): 124515468 Help Entry 124515468         CDS       T08475                                  Name (RefSeq) caspase-8-like   KO K04398   caspase 8 [EC:3.4.22.61] Organism lruf  Lynx rufus (bobcat) Pathway lruf01524   Platinum drug resistance lruf04115   p53 signaling pathway lruf04210   Apoptosis lruf04215   Apoptosis - multiple species lruf04217   Necroptosis lruf04620   Toll-like receptor signaling pathway lruf04621   NOD-like receptor signaling pathway lruf04622   RIG-I-like receptor signaling pathway lruf04623   Cytosolic DNA-sensing pathway lruf04625   C-type lectin receptor signaling pathway lruf04657   IL-17 signaling pathway lruf04668   TNF signaling pathway lruf04932   Non-alcoholic fatty liver disease lruf04936   Alcoholic liver disease lruf05010   Alzheimer disease lruf05016   Huntington disease lruf05022   Pathways of neurodegeneration - multiple diseases lruf05132   Salmonella infection lruf05134   Legionellosis lruf05142   Chagas disease lruf05145   Toxoplasmosis lruf05152   Tuberculosis lruf05160   Hepatitis C lruf05161   Hepatitis B lruf05162   Measles lruf05163   Human cytomegalovirus infection lruf05164   Influenza A lruf05165   Human papillomavirus infection lruf05167   Kaposi sarcoma-associated herpesvirus infection lruf05168   Herpes simplex virus 1 infection lruf05169   Epstein-Barr virus infection lruf05170   Human immunodeficiency virus 1 infection lruf05200   Pathways in cancer lruf05203   Viral carcinogenesis lruf05416   Viral myocarditis lruf05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:lruf00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     124515468  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     124515468    04215 Apoptosis - multiple species     124515468    04217 Necroptosis     124515468    04115 p53 signaling pathway     124515468  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     124515468    04621 NOD-like receptor signaling pathway     124515468    04622 RIG-I-like receptor signaling pathway     124515468    04623 Cytosolic DNA-sensing pathway     124515468    04625 C-type lectin receptor signaling pathway     124515468    04657 IL-17 signaling pathway     124515468  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     124515468    05203 Viral carcinogenesis     124515468   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     124515468    05161 Hepatitis B     124515468    05160 Hepatitis C     124515468    05164 Influenza A     124515468    05162 Measles     124515468    05168 Herpes simplex virus 1 infection     124515468    05163 Human cytomegalovirus infection     124515468    05167 Kaposi sarcoma-associated herpesvirus infection     124515468    05169 Epstein-Barr virus infection     124515468    05165 Human papillomavirus infection     124515468   09171 Infectious disease: bacterial    05132 Salmonella infection     124515468    05134 Legionellosis     124515468    05152 Tuberculosis     124515468   09174 Infectious disease: parasitic    05145 Toxoplasmosis     124515468    05142 Chagas disease     124515468   09164 Neurodegenerative disease    05010 Alzheimer disease     124515468    05016 Huntington disease     124515468    05022 Pathways of neurodegeneration - multiple diseases     124515468   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     124515468    05416 Viral myocarditis     124515468   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     124515468    04932 Non-alcoholic fatty liver disease     124515468   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     124515468  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:lruf01002]     124515468 Enzymes [BR:lruf01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      124515468 Peptidases and inhibitors [BR:lruf01002]  Cysteine peptidases   Family C14: caspase family    124515468 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  124515468 NCBI-ProteinID:  XP_046940318 LinkDB All DBs Position Unknown AA seq 479 aa AA seqDB search MDFSKCLYNIGEQLGSDELASLKFLSLDYIPQKKQEPIKDALMLFQRLQEKRMLEESNLS FLKELLFRINRLDLLFNYLNTSKEAMEQELQIPGRAQIPPYRVMLFQISEDVNKLELRSF KFLLSQEISRCKVDDDMNLLDIFIEMEKRVILGERNLDTLKRICDQINKSLLKKITDYEE LSREGRMSLQRSPDELSNGEESLAMMALSDSLEEQDSESQTSDKVYRMKSKPRGYCLIFN NYDFSRARKDVPKLQNIKDRNGTNFDAEALSKTFSELHFEIVNFKDSTAKTICEVLKSYQ RMDHNNKDCFICCILSHGDKGIIYGSDGQEAPIYELTSYFTGSKCPSLAGKPKIFFIQAC QGDNYQRGIAVETDSEQKEDYLEMDSSFQKRYIPDEADFLLGMATVNNCVSYRNPTEGTW YIQSLCQSLRERCPRGEDILTILTEVNFEVSNKDDKKNMGKQMPQPTFTLRKKLFFPLN NT seq 1440 nt NT seq  +upstreamnt  +downstreamnt atggatttcagtaaatgtctgtataatattggggaacagctgggcagtgacgagctggcc tccctcaaattcctgagcctggactacatcccacaaaagaaacaagaacccatcaaagat gccttgatgttattccagagactccaggaaaagagaatgttggaggaaagcaacctgtcc ttcttgaaggagctgcttttccgaattaatagactggacctgctgttcaactacctgaac accagcaaggaagcaatggagcaggagcttcagataccaggcagagcccagatccctccc tacagggtcatgctttttcagatttcagaagatgtaaacaaattggaattgaggtcgttt aagtttcttttgagccaggagatctccagatgtaaagtggatgatgatatgaacttgctt gatattttcatagagatggaaaagagggtcatcctaggggaaagaaatttggacactctg aaaagaatctgtgaccaaatcaacaagagcctgctgaagaaaatcactgattatgaagaa ttaagcagagagggaagaatgagccttcaaagaagtccagatgaattgtcaaatggggag gaatccctggcaatgatggcattatcggactctctagaagaacaggacagtgagtcacag acatcggacaaagtttaccgaatgaaaagcaaacctcgcggatattgtttgatctttaac aattatgattttagcagagcacggaaggatgtgcccaaacttcagaacattaaggatagg aatggaacaaacttcgatgcagaagctttgagtaagacctttagtgagcttcattttgag attgtgaatttcaaagactctacagcaaagacaatctgtgaagttctgaaatcctaccaa agaatggaccataataacaaagattgcttcatctgctgtatcctctcccatggagacaaa ggcattatttatggctctgatgggcaggaagcccccatctatgagctgacttcttacttc actggttcaaagtgcccttcccttgcaggcaagcccaaaatcttttttattcaggcttgt caaggggataactaccagagaggtatagctgttgagactgactccgaacagaaggaagac tacttagaaatggactcatcatttcagaagagatatatcccagatgaggctgattttctg ctggggatggccactgtgaacaactgtgtttcctaccgaaaccctacggaggggacctgg tatatccagtcactttgccagagcctaagagaaagatgtcctaggggcgaagatatcctc accatccttactgaggtgaactttgaagtgagcaataaggatgacaagaaaaacatgggg aaacaaatgccacaacctacttttacactgaggaaaaaactcttcttccctcttaattga

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