KEGG   Lynx rufus (bobcat): 124522669
Entry
124522669         CDS       T08475                                 
Name
(RefSeq) fibroblast growth factor receptor 3 isoform X1
  KO
K05094  fibroblast growth factor receptor 3 [EC:2.7.10.1]
Organism
lruf  Lynx rufus (bobcat)
Pathway
lruf01521  EGFR tyrosine kinase inhibitor resistance
lruf04010  MAPK signaling pathway
lruf04014  Ras signaling pathway
lruf04015  Rap1 signaling pathway
lruf04020  Calcium signaling pathway
lruf04144  Endocytosis
lruf04151  PI3K-Akt signaling pathway
lruf04550  Signaling pathways regulating pluripotency of stem cells
lruf04810  Regulation of actin cytoskeleton
lruf05200  Pathways in cancer
lruf05206  MicroRNAs in cancer
lruf05219  Bladder cancer
lruf05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:lruf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    124522669
   04014 Ras signaling pathway
    124522669
   04015 Rap1 signaling pathway
    124522669
   04020 Calcium signaling pathway
    124522669
   04151 PI3K-Akt signaling pathway
    124522669
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    124522669
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    124522669
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    124522669
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    124522669
   05206 MicroRNAs in cancer
    124522669
   05230 Central carbon metabolism in cancer
    124522669
  09162 Cancer: specific types
   05219 Bladder cancer
    124522669
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    124522669
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lruf01001]
    124522669
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:lruf04090]
    124522669
Enzymes [BR:lruf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     124522669
Protein kinases [BR:lruf01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   124522669
CD molecules [BR:lruf04090]
 Proteins
  124522669
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set Ig_3 ig Ig_2 FGFR3_TM V-set C2-set_2 ABC1 Pkinase_fungal
Other DBs
NCBI-GeneID: 124522669
NCBI-ProteinID: XP_046950216
LinkDB
Position
Unknown
AA seq 803 aa
MGALARALAFCVAVAVVTGAASGPPGMEQRVVRRAAEAPGPEPGPQEQLVFGSGDTVELS
CHLPAGGPTGPSVWVKDGVGLAPSDRILVGPQRLQVLNASHEDAGAYSCRQRLTQRVLCD
FSVRVTDAPSSGDDEDGEDEAEDTAGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPT
PSISWLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTL
DVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGT
PYVTVLKTAGANSTDKELEVLSLRNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEEL
LEAGAAGSVYAGVLSYGAGFLLFILVVAAVTLCRLHSPPKKGLGSPTVHKVSRFPLKRQV
SLESNSSMNSNTPLVRIARLSSGEGPALANVSELELPADPKWELSRARLTLGKPLGEGCF
GQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGRHKNIINLLG
ACTQGGPLYVLVEYAAKGNLREYLRARRPPGMDYSFDTCKLPEEQLTCKDLVSCAYQVAR
GMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAP
EALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDL
YTIMRECWHAVPSQRPTFKQLVEDLDRILTVTSTDEYLDLSVPFEQYSPGGQDTPSSSSS
GDDSVFAHDLLPPAPPGGGGPRT
NT seq 2412 nt   +upstreamnt  +downstreamnt
atgggcgccctggctcgcgccctcgcgttctgcgtggccgtggcggtcgtgaccggcgcc
gcctcggggccccccggcatggagcagcgcgtcgtgcggagagcggcagaggccccggga
cctgagcccggcccgcaggagcagctggtctttggcagcggggacaccgtggagctgagc
tgccacttgcctgcaggtggccccacagggcccagcgtttgggtcaaggacggtgtgggg
ctggcgccctcagaccgcatcctggtggggcctcagcggctgcaggtgctgaacgcctcc
cacgaggacgcgggggcctacagctgccggcagcggcttacccagcgcgtgctatgcgac
ttcagcgtgcgtgtgacagatgccccgtcctccggggatgacgaagacggagaggatgag
gctgaggacacagccggggccccttactggacgcggcccgagcggatggacaagaagctg
ctggctgtgccggccgccaacaccgtccgcttccgctgcccggccgccggcaaccccact
ccgtccatctcttggctgaagaacggcaaggagttccggggggagcaccgcatcgggggc
atcaagctgcgacaccagcagtggagcctggtcatggagagcgtggtcccgtcggaccgc
ggcaactacacgtgcgttgtcgagaacaagttcggcagcatccgacagacctacaccctg
gacgtgctggagcgctctccgcaccggcccatcctgcaggcggggctgccggccaaccag
acggcggtgctgggcagcgacgttgagttccactgcaaggtgtacagcgacgcccagccc
cacatccagtggctgaagcacgtggaagtgaacggcagcaaagtggggcccgacggcacc
ccctatgtcaccgtgctcaagacggcgggcgctaacagcaccgacaaggagctagaggtt
ctgtccttgcgcaatgtcacctttgaggacgcgggggagtacacgtgtctggcgggcaat
tctatcgggttttcccatcactctgcgtggctggtggtgctgccagccgaggaggagctg
ctggaggccggtgcggcgggcagcgtgtatgcgggcgtcctcagctacggggcgggcttc
ctcctcttcatcctggtggtggccgccgtgacactgtgccgtctgcacagtcccccgaag
aagggcctgggctcgcccaccgtgcacaaggtctcccgctttccactcaagcgacaggtg
tccttggagtccaactcgtccatgaactccaacacgccgctggtgcgaatcgcccggctg
tcttccggggagggtcctgcgctggccaacgtctccgagctcgagctgcccgccgacccc
aagtgggagctgtccagggcccggctgaccctgggcaagcctctcggggagggctgcttt
ggccaagtggtcatggcagaggccatcggcattgacaaggaccgggccgccaagcctgtc
actgtggccgtgaagatgctgaaagacgacgccacagacaaggacctgtcggatctggtg
tcggagatggagatgatgaaaatgatcggcagacacaagaacatcatcaatctgctgggg
gcctgcacgcagggcgggcccctgtacgtgctggtggagtacgcggccaaggggaacctg
cgcgagtacctgcgggcgcggaggccgccaggcatggactactccttcgacacgtgcaag
ctgcccgaggagcaactcacctgcaaggacctggtgtcttgtgcctaccaggtggcgcgg
ggcatggagtacctggcctcgcagaagtgcatccacagggacctggcggcccgcaacgtg
ctggtgaccgaggacaacgtgatgaagattgcggactttggtctggcccgcgacgtgcac
aaccttgactactacaaaaagaccaccaatggccggctgcccgtgaagtggatggcaccc
gaggccttgtttgatcgagtctacacccaccagagtgacgtctggtccttcggggtcctg
ctctgggagatcttcactctggggggctcgccgtaccccggcatccccgtggaggagctc
ttcaagctgctgaaagagggccaccgcatggacaagccggccaactgcacacacgacctg
tacacgatcatgcgggagtgctggcacgcggtgccctcgcagaggcccaccttcaagcag
ctggtggaggacctggaccgcatcctcaccgtcacgtccaccgatgaatacctagacctg
tcggtgcccttcgagcagtactcgccgggcggccaggacacccccagctccagctcttcg
ggggacgactccgtgtttgcccacgacctgctgcctccggcccctcccggcggcgggggc
cctcggacgtga

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