Lynx rufus (bobcat): 124523034
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Entry
124523034 CDS
T08475
Name
(RefSeq) tyrosine-protein kinase JAK3 isoform X1
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
lruf
Lynx rufus (bobcat)
Pathway
lruf04062
Chemokine signaling pathway
lruf04151
PI3K-Akt signaling pathway
lruf04217
Necroptosis
lruf04550
Signaling pathways regulating pluripotency of stem cells
lruf04630
JAK-STAT signaling pathway
lruf04658
Th1 and Th2 cell differentiation
lruf04659
Th17 cell differentiation
lruf05161
Hepatitis B
lruf05162
Measles
lruf05166
Human T-cell leukemia virus 1 infection
lruf05169
Epstein-Barr virus infection
lruf05200
Pathways in cancer
lruf05203
Viral carcinogenesis
lruf05223
Non-small cell lung cancer
lruf05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
lruf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
124523034
04151 PI3K-Akt signaling pathway
124523034
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
124523034
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
124523034
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
124523034
04659 Th17 cell differentiation
124523034
04062 Chemokine signaling pathway
124523034
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
124523034
05203 Viral carcinogenesis
124523034
09162 Cancer: specific types
05223 Non-small cell lung cancer
124523034
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
124523034
05161 Hepatitis B
124523034
05162 Measles
124523034
05169 Epstein-Barr virus infection
124523034
09163 Immune disease
05340 Primary immunodeficiency
124523034
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lruf01001
]
124523034
Enzymes [BR:
lruf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
124523034
Protein kinases [BR:
lruf01001
]
Non-receptor tyrosine kinases
JAK family [OT]
124523034
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
SH2_1
FERM_F1
Jak1_Phl
ABC1
Kdo
Kinase-like
FERM_C_FAK1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
124523034
NCBI-ProteinID:
XP_046950728
LinkDB
All DBs
Position
Unknown
AA seq
1106 aa
AA seq
DB search
MAPPSEETPLIPQRSCSLSSSEAGALHVLLPPRGPGPPQRLSFSFGDHSAEKLCVWAAKA
SGILPVYHSLFALATEDLSYWYPPSHIFSVEDASTQVLLYRLRFYFPNWFGLEKCHRFGL
RKDLASAILDLPVLEHLFAQHRNDLVSGRLAVGLSLKEQGECLSLAVLDLARMVREQVQQ
PEELLKTVSYKACLPPDLRDLIQGLSFVTRKRIRRTVRRALGRVTACQADRHSLMAKYIM
DLERLDPARAAETFLVSLPGAAGGQDAPGLLRVAGDSGIHWSPGGHEALQPFCDFPEIVD
ISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPAALSFVALVDGYFRLTSDSRHFFC
KEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSLPGSYVLRRSPQDFDSFLLTVCVQTP
LGPDYKGCLIRCDPTGTFSLAGLGRPHSSLRELLAACWDAGLHVDGVALNLTSCCAPRPK
EKSNLIVVRRGCSTPTSSLVWPQSQCQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCR
HEAVDGEARETEVLLKVMDAKHRNCMESFLEAASLMSQVSYQHLVLLHGVCMAGDSVMVQ
EFVRLGALDTYLRKSGHLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKVLLAREGA
DGNLPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEARTLGLEADKWGFGATVWEVFS
GIPMPISTLDPAKKLQFYEERQRLPAPKWMELATLIQQCMAYEPGQRPSFRAIIRDLNSL
ITSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCR
YDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRL
VMEYLPSGCLRDFLQRHRARLDASRLLLYASQICKGMEYLGSRRCVHRDLAARNILVESE
THVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYEL
FTYGNKNCSPSAEFLRMMGCERDVPALCRLLELLAEGQRLPAPPACPGEVHELMKLCWAP
SPQDRPTFSALGPQLDTLWSGSRGVA
NT seq
3321 nt
NT seq
+upstream
nt +downstream
nt
atggcgcctccaagtgaggagacgcccctgatccctcagcgttcctgcagcctctcgtct
tcagaggctggtgccctgcacgtgctgctgccccctcggggccccggacccccacaacgc
ctgtccttctcctttggggaccattcagctgaaaagctatgtgtttgggctgctaaggcc
agtggcatcctgcctgtgtaccactccctctttgctctggccacggaggacctgtcctac
tggtaccccccgagccacatcttctccgtggaggatgcaagcacccaagtcctgctctac
aggctccgcttttacttccccaactggtttgggttggagaaatgccaccgcttcgggcta
cggaaggacttggccagtgccatccttgacctgccagtcctggagcacctcttcgcccag
caccgaaatgacctggtgagcggccgcctcgccgtgggcctcagtctcaaggagcagggt
gaatgtctcagcctggcagtgctggacctggctcggatggtccgtgagcaggttcagcag
cctgaggagctgctgaagaccgtcagctacaaggcctgcctgccccccgatctgcgcgac
ctgatccagggcctgagcttcgtgacgcggaagcgtatccggaggactgtgcgccgggcc
ctgggccgcgtgaccgcctgccaggctgacaggcactcgctcatggccaagtacatcatg
gacctggagaggctggacccggccagggccgccgagaccttcctcgtgagcctccccggg
gctgctggtggccaggatgctccggggctgctccgagtggctggtgacagcggcatccac
tggagtccgggaggacacgaggccctccagcccttctgcgactttccagaaattgtggac
atcagcatcaagcaggctcctcgtgttggccccgccggggagcaccgcctggtcaccgtc
accaggacggacaaccagatcctggaggccgagttcccggggctgcccgcggccctgtcc
ttcgtggcgctcgtggacggctacttccggctgacttccgactccaggcacttcttctgc
aaggaggttgcgccgccgcggctgctggaggaggtggccgagcagtgccacggtcccatc
accctggattttgccatcaacaagctcaagaccgggggctcccttcccggctcctatgtt
ctccgccgcagcccccaggatttcgacagcttcctcctcactgtctgcgtccagaccccc
ctgggtcctgattacaagggctgcctcatccggtgtgaccccacgggaaccttctccctg
gctggcctcggccggccccacagcagtcttcgagagctcttggcagcctgctgggatgct
gggctgcacgtggatggggttgcgctgaacctcacctcctgctgcgcccccagacccaaa
gaaaagtccaacctgatcgtggtgcggagaggttgcagcactcccacatcatcccttgtt
tggccccaatcccagtgccagctgagtcagatgacgtttcacaagatccctgctgacagc
ctggagtggcatgagaacctgggtcatgggtccttcaccaagatttaccgaggttgtcgc
catgaggctgtggacggggaagcccgggagacagaggtgctactcaaagtgatggatgcc
aagcacagaaactgcatggagtccttcctggaagcagcgagcctgatgagccaagtgtcg
tatcagcacctcgtgttgctccacggcgtgtgcatggcgggagacagtgtcatggtgcag
gaatttgtgcgcctgggagccctggatacatatctgcgcaagtctggccacctggtacca
gccagctggaagctgcaggtgatcaagcagctggcctatgccctcaactatctggaagac
aaaggcctcccccatggcaatgtctcggcccggaaggtgctcttggctcgggagggggct
gacgggaacctgcccttcatcaagttgagtgaccctggtgtcagccccaccgtgctgagc
ctggagatgctcactgacaggatcccctgggtggcccctgagtgtctccaggaggcccgg
acccttggcttggaagctgacaagtggggtttcggtgccacagtctgggaagtgttcagc
gggatcccgatgcccatcagtaccctggatcctgccaagaagctccagttttacgaggaa
cggcagcgccttcctgcccccaagtggatggagctggccacactgatccaacagtgcatg
gcctatgagccaggccagaggccctccttccgcgccatcatccgtgacctgaacagcctc
atcacttcagattatgagctcctctcagaccccacacctggtgccttggcgccccgtgat
gggctgtggaatggcgcccagctctacgcctgccaggaccctaccatttttgaggagaga
catctcaagtacatctcacagctgggcaagggcaactttggcagcgtggagctgtgccgc
tatgacccgctgggcgacaacacgggggccctagtggctgtgaagcagcttcagcacagc
gggccagaccagcagagggacttccagcgggagatccagatcctcaaagccctccacagc
gacttcattgtcaagtaccgcggtgtcagctatggcccgggccgccagagcctgcggctg
gtgatggagtacctgcccagcggctgcctgcgcgacttcctgcagcgacaccgcgcgcgc
ctcgacgccagccgcctgctcctctacgcctcgcagatctgcaagggcatggagtacctg
ggctcccgccgctgcgtgcaccgcgacctggcggcccgtaacatcctggtggagagcgag
acgcacgtcaagatcgccgactttggcctcgccaagctgctgccgctcgacaaagactac
tacgtggtccgcgagcccggccagagccccatcttctggtacgccccagagtccctctct
gacaacatcttctcgcgccagtcggacgtctggagcttcggggtcgtcctgtacgagctt
ttcacctacggcaacaagaattgcagcccctcggccgagttcctccggatgatgggatgt
gagcgagacgtccccgccctctgccgcctcctggagctgctggctgagggccagaggctg
cccgcgcctcctgcctgccccggtgaggttcatgagctcatgaagctgtgctgggccccg
agcccgcaagatcggccaacattcagtgccctgggcccccagctggatacactgtggagt
ggaagccggggggtagcatag
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