KEGG   Lysinibacillus sphaericus: Bsph_0176
Entry
Bsph_0176         CDS       T00656                                 
Name
(GenBank) Methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
lsp  Lysinibacillus sphaericus
Pathway
lsp00270  Cysteine and methionine metabolism
lsp00450  Selenocompound metabolism
lsp00670  One carbon pool by folate
lsp01100  Metabolic pathways
lsp01110  Biosynthesis of secondary metabolites
lsp01230  Biosynthesis of amino acids
lsp04980  Cobalamin transport and metabolism
lsp04981  Folate transport and metabolism
Module
lsp_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:lsp00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    Bsph_0176
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    Bsph_0176
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Bsph_0176
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    Bsph_0176
   04980 Cobalamin transport and metabolism
    Bsph_0176
Enzymes [BR:lsp01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     Bsph_0176
SSDB
Motif
Pfam: S-methyl_trans Met_synt_B12 Pterin_bind B12-binding B12-binding_2 CdhD
Other DBs
NCBI-ProteinID: ACA37810
UniProt: B1HTR9
LinkDB
Position
193619..197050
AA seq 1143 aa
MAKHLIEEQLDKRILILDGAMGTMLQNENLTADDFGGEELDGCNENLVLTRPDVIEKIHH
KYLEAGADIICTNTFGGTPLVLNEYSLGAKAEEINKRAVEIARQAVDNYSTSDWPRFVAG
AMGPTTKTLSVTGGITFDELEENFYVQAKALIEAGADVLLLETSQDMLNVKAGTLGVTRA
FEKTGKELPVMISGTIEPMGTTLAGQTIDAFYISIEHIQPLSVGLNCATGPEFMTDHIRS
LAELSTGYISCYPNAGLPDEEGCYHESPESLSQKLKGFAEKGWLNIVGGCCGTTPAHIAA
IREALKDEKPRQLPEKTHGHVVSGIEPLLYDDSMRPLFIGERTNVIGSRKFKNLIIDGKF
EEAAEIARAQVKNGAHVIDICLANPDRDELADIRGFMQEVVKKVKVPLVIDSTDEKVIEE
ALKFSQGKAIINSINLEDGEERFDAVLPLVKKYGASLVVGTIDETGMAVDRHRKLEIAER
SYQLLTEKWGIEPEDIIFDPLMFPVGTGDEQYIGSALETIEGIRLIKEKMPRTLTVLGVS
NISFGLPPVGREVLNAVYLYHCTQAGLDYAIVNTEKLERYASIPEAEIKLANDLLFNTND
ETLAVFTDFYRDKKKEKTEADIPKTVEGRLAYYILEGTKEGLIADLEAAREIFETPLDII
NGPLMNGMAEVGRLFNDNQLIVAEVLQSAGVMKAAVAHLEQYMEKNEESAGKGKMVLATV
KGDVHDIGKNLVDIILSNNGYKVVDLGIKVTPAQLIEAIRKEKPDFIGLSGLLVKSAQQM
VTTAQDFKEAGIDVPILVGGAALSRRFTETKIADEYGGPVIYSKDAMQGLEQANLLMGEG
TRENFLAEIAESRQKRLEADEKRAARPAKEVTIKPARTVKEAPVFLPADLRRHVKKEYAV
SHLYPYVNMRTLLGHHLGLKGQVQPLLDAGDPRATELKDLVDDYLKSDLLKPSGLYQFFP
AQADGDDVIIYDPADSKTEIERFTFPRQQIDPFLCLADFLRTVESGEMDYIALMVVTAGQ
GVMAKARQLKEDGKFLESHALQSTALELAEGFAERMHQEIRDQWGFPDVTDFTMRDRFAA
KYQGQRFSFGYPACPNLEDQEKLFGLLKPEDIGVHLTEGFMMEPEASVSAIVFAHPDARY
FNV
NT seq 3432 nt   +upstreamnt  +downstreamnt
atggctaagcacttaattgaagaacaacttgataaacgaatattaattcttgatggcgcg
atgggaacaatgctgcaaaatgaaaacttaacagcagatgattttggcggggaggagcta
gatgggtgtaatgaaaatctagtgctaactagacctgatgtcattgaaaaaatacatcat
aaatacttagaggcaggagcagatattatttgtacgaatacattcggtggaacaccactt
gtattaaatgaatatagtctgggtgcaaaagcggaggaaattaataaacgtgcagtcgag
attgctcgccaagcagtagataattattctacttctgattggccccgctttgttgctggt
gcaatgggtccaacaactaaaacactatccgtaacaggtggtattacatttgatgaatta
gaagaaaatttttatgtacaagcaaaggcattgattgaagcaggtgcagatgtgctttta
ctagagacaagtcaggatatgttaaatgtgaaagcaggtacccttggggtaacgcgtgct
ttcgagaaaactggcaaagagctacctgttatgatttctggaacgattgagcctatgggt
actactcttgcaggacaaaccattgatgctttttatatttccatcgagcatattcaacca
ctatcagtgggcttaaactgtgcaacgggaccggaatttatgacggatcatatacgctcg
ttagcagagctgtcaacagggtatattagctgttatccgaatgcaggcttaccggatgag
gaaggatgttatcatgagtctccagaatctttatcgcaaaaattaaaaggatttgcagaa
aaaggttggctcaatattgtaggtggatgctgtggtacaactccagcacatattgcggcc
attcgtgaagctttaaaggatgaaaagcctcgtcagctaccagaaaaaacgcatggtcac
gtagtatcagggatcgagccacttctatacgatgattctatgcgtccgttatttattggg
gaaagaacaaatgttattggttcccgcaaatttaaaaacttaattattgatggaaagttt
gaggaagcggctgagattgcaagggcgcaagtgaaaaacggcgcacatgtcatagatatt
tgtttagcgaacccagatcgggatgaattagcagatatccgtggctttatgcaggaggtc
gtaaaaaaagtgaaggttccacttgttattgattccacagacgaaaaggttattgaagag
gcactcaaattttcgcaaggaaaggccatcattaactctattaatctagaagatggcgaa
gaacgatttgatgcagtattgccattagtgaaaaagtatggtgcctcgttagttgtggga
acaatcgatgagacagggatggcagtcgatcgtcatcggaagcttgaaattgctgagcgt
tcctatcaattactaacagaaaaatggggaattgaacctgaagatatcatctttgaccca
ttaatgttcccagtaggaacgggggatgagcaatatattggctcagcacttgaaacaatt
gaaggaatacgtctcatcaaagaaaaaatgcctcgtactttaacggtgcttggcgttagt
aatatttcgtttggcttaccaccggttggacgcgaagttctcaatgctgtatatctttat
cattgtacacaggctggtttagattatgccattgtaaataccgagaagctagaacggtac
gcatctattccagaagcagaaataaaactagccaatgatttgttatttaatacaaatgat
gaaacattagctgtatttaccgatttttatcgtgacaaaaagaaggaaaagacggaagct
gatattccgaaaactgtagaaggtcgcttagcctactatatattggaagggaccaaagaa
ggacttattgctgatttagaggctgcccgagaaatatttgagacacctcttgatatcata
aatggacctcttatgaatggtatggctgaggttggtcgtttatttaatgataaccaactg
atcgtagcggaggttttacaatctgctggagtgatgaaggctgctgttgcccatttagag
caatacatggagaagaacgaggagagcgctggtaagggtaaaatggtgcttgctactgta
aaaggtgatgtgcatgatattggaaaaaaccttgttgatattattttaagtaataatggc
tataaggttgtagatttaggtatcaaggtgacgcctgctcaattaatagaagctattcgc
aaggaaaagccagatttcatcggattatcaggtttattagtcaaatctgcccagcaaatg
gtcactaccgctcaagatttcaaagaagcgggaattgatgtacccattttagtaggagga
gctgcactttctcgacgttttacagaaacaaaaattgctgatgaatatggtggtcctgtt
atttattcaaaggatgcgatgcaaggattagagcaggcaaatttactaatgggtgagggg
acacgtgaaaacttcttagcagaaatagcggaatctcgacaaaaacgtttagaggcagat
gaaaaaagagcggctcgtcctgccaaagaggtcacaataaaacctgcgcgtaccgtaaag
gaagcaccagtttttttacctgctgatttacgccgtcatgtaaagaaagaatacgctgtc
tctcatttatatccatatgtgaatatgcggacattgttggggcatcatttggggttaaaa
gggcaagtgcaaccattactagatgctggcgatccaagagctacagagctaaaagattta
gtggatgattatttaaaaagtgatttattaaagccttcaggtttatatcaatttttccct
gcccaagcagatggagatgatgtaattatttatgatccagcggatagcaagacagaaatt
gaacgttttacattcccacgtcagcagatagacccttttttatgcctggctgatttctta
agaacggtagaaagtggagaaatggattatattgcccttatggtagtgacagcagggcaa
ggagttatggcaaaagctcgtcagctaaaagaagatggcaaattccttgaaagtcatgcc
ttgcagtcgacggcactagaattagcagagggctttgctgaacgcatgcatcaagaaata
cgtgatcaatggggtttcccagatgtgacagatttcacgatgcgcgatcgttttgcggct
aagtaccagggacaacgtttttcatttggttatccagcatgcccaaacttagaggatcaa
gaaaaattatttggtttactaaagccagaagatattggtgttcatttaacggaaggcttt
atgatggagccagaagcatctgtatcggcgattgtttttgctcaccctgatgctcgttat
ttcaatgtgtaa

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