KEGG   Leptospira santarosai: LSS_10333
Entry
LSS_10333         CDS       T03999                                 
Name
(GenBank) multidrug transporter AcrB
  KO
K18138  multidrug efflux pump
Organism
lst  Leptospira santarosai
Pathway
lst01501  beta-Lactam resistance
lst01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:lst00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    LSS_10333
   01503 Cationic antimicrobial peptide (CAMP) resistance
    LSS_10333
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:lst02000]
    LSS_10333
   01504 Antimicrobial resistance genes [BR:lst01504]
    LSS_10333
Transporters [BR:lst02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   LSS_10333
Antimicrobial resistance genes [BR:lst01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    LSS_10333
SSDB
Motif
Pfam: ACR_tran MMPL DUF5528 ZT_dimer
Other DBs
NCBI-ProteinID: EKT86838
UniProt: K8XZI3
LinkDB
Position
I:complement(3421007..3424162)
AA seq 1051 aa
MLSNVSIRNPIFSWMMMSAIIIFGSVGFSKMGVSQMPDVDFPVVNVSLTLVGANAQVMET
DVVDPIEEVLMAVEGVTEVRSISSDGSATITVELELSRNVDVAVQEIQTKLAQVSNKLPE
ELEPAVITKSNPDDVPIIWVSVTAIDKTEKEKMLFVKDFLKDKFQKISGVGEIILGGYVD
RTINVYLDPIKLSRNEIAVDDIVNTLREQNLEVPSGRLENRTNEIGLRAVGEVPTAEQFG
NIFLNSRSGSPLFRSIRLKDIAIVEDGLGEVRRISRFNGISAVAIGIKKLKGANAVQVGE
LVKAKVEELKPKLPKGYDLTVSNDNTGYIRDSVNELEFTLIFSAILTGFVCRLFLGNWKS
TGNVLLAIPTSVIGTFLFLYFAGFTVNTFTMLGLSLATGIVVDDAIMVLENITRHREMGK
SWYKAALEGALEIRFAALAATLAVVAIFLPVAFMKGIIGRYFLEFGVTISVSVLLSLFEA
LSFTPMRASLYAEDQGKNGKKFLFFSVFSTNAYETWNLRISKVSIFKRMDPVVERFLDYS
TNLYGRSIDFVLKYPRWIVFGSTALFVLSLGFFFLLKKEFIPPQDMGRFIVRVRLPLGSS
LQKTDEAMKKVERYLIDRKEIEKYISNVGGFGGTESNAGMFFITMKEMGHRPKNPKTGKE
ITQSALFGILRKDLKGLVPEATFSMQDLSQRGFSAGRGYPVELVLTGPDWKTLSSLSVQI
LEKLKESNAVLDVDTDYVAGQKELRLITDREAAALRGVSMANVGNTVGTLMGGKNVSRFT
ENGRSYDVRVKIRKEQGETIAVIPDISVRNTFGEFVKLKEVVSIQEKEALKTITRINRER
AIRVFGNPAPALGQTVSTEKALEIAGEILPEGYSVSITGSAKTAKESGESLTLALAFGIL
LSYMILASQFNSLKQPLYILLAMPFSFTGALVALYAFGQSFNMYSFIGLILLLGLVKKNS
ILLVEFVNQVRTTGKNVRESIQEGCPIRLRPVLMTSFSSIAAAIPPALALGPGAETRIPM
AVTILGGMTLSTLITLLVVPAAYYLGEKEKR
NT seq 3156 nt   +upstreamnt  +downstreamnt
ttgctctctaacgtatcgatacgcaatccgattttttcttggatgatgatgtccgcgatt
attatatttggatcggtcggattttccaaaatgggcgtttcccaaatgcctgatgtcgac
tttccggtagtcaacgtctctctcacactcgtaggcgccaacgctcaagttatggaaacc
gacgtagtcgatccgattgaagaagttctaatggccgtcgaaggagtcaccgaagttcgt
tcgatttcttccgacggttccgcgactataaccgtagaattggaactcagccgaaacgtg
gatgtcgccgttcaagagattcaaacaaaactggctcaggtatccaataaacttccggag
gaattggaaccggcggtgattacgaagtccaatccggacgatgttccgatcatttgggtt
tccgtgactgcgattgataagaccgaaaaggaaaagatgcttttcgtgaaggattttctg
aaagataagtttcagaaaatttcgggagtgggggaaatcattctcggaggttacgttgat
cgaacgatcaacgtctatttggatccgatcaaactttccagaaacgaaatcgccgtggac
gatattgtcaacactttgagggaacagaatttggaggttccttccggaaggttggaaaat
aggacgaatgaaatcggtcttcgagcagtgggggaggtccccacggcggaacaattcggc
aacatatttttaaattcaagaagcggctctcctctttttagatcgatccgactcaaagat
atcgcaatcgtagaagacgggttaggcgaggtaaggagaatatcccgttttaacggaatt
tccgccgtcgcgatcgggatcaaaaaactcaaaggagccaacgcggttcaagtcggagaa
cttgttaaagcgaaggtcgaagaattaaagccgaaacttccgaagggttacgatcttacc
gtttccaacgataacaccggttatatccgagacagcgtaaacgaactcgaattcactctg
attttttccgcaattcttaccggttttgtgtgtaggttatttttgggaaattggaaaagc
acgggaaacgttcttcttgcaattccgacttcggtgatcggaacgtttttgtttttgtac
tttgcgggttttacggtcaacacctttacgatgttgggtttgtctcttgcgaccggaatt
gtggtggatgacgcgattatggttttggaaaatattaccagacatcgtgagatgggaaag
tcctggtataaagccgcactggaaggggctttggaaattcggtttgcggctttagcggcc
acgttagccgtcgttgcgatctttcttcccgttgcatttatgaaagggatcatcggaaga
tactttttggaattcggagttacgatttccgtttcggttcttctttccctattcgaagcg
ttgagttttactccgatgcgcgcttccctgtatgcggaagatcaggggaaaaatggaaag
aagtttttattcttttccgtcttttcaacgaacgcgtatgaaacctggaatcttcggatc
tcaaaggtttcgatcttcaaaagaatggatcctgtcgtcgagagattcttggattatagt
acgaatctctacggtcgttcgatcgatttcgtattaaaatatccgcgttggatcgtattc
ggatcgacggccttgtttgtcttatctctcggattttttttccttttgaaaaaagaattt
attccacctcaggacatgggtcgttttatcgttcgagtcaggctgccattgggttcttcc
ttgcagaaaacggacgaagcgatgaaaaaagtggaacggtatctgatcgatcgaaaggaa
atcgaaaaatacatatccaacgtcgggggttttgggggaaccgagtcaaatgcgggaatg
ttctttatcacgatgaaggaaatgggacacaggccgaaaaatcctaaaaccggaaaagag
atcactcagtcggcgcttttcggaattttaagaaaggatttaaagggactggtaccggaa
gcaacgttctctatgcaggatctttcgcagaggggattttccgcgggaaggggttatccc
gtcgaacttgtgttaaccggtccggattggaaaacgttatcctccctttcggttcaaata
ttagaaaaattgaaagaaagcaatgcggtgttggacgtggatacggattacgtcgccgga
caaaaagaactcaggctgattaccgatcgggaagccgccgcactcagaggtgtgagtatg
gcgaacgtaggaaacacggtcggaacattgatgggcggaaagaacgtaagtcggtttacg
gaaaacggaagaagttacgatgtaagagtaaaaatccgaaaggagcagggagaaacgatc
gccgttattccggatatcagcgttcgaaacactttcggcgaattcgtcaaactcaaagaa
gttgtgagtattcaggaaaaggaagctttgaaaacgatcactcggatcaatcgggagaga
gcgatccgagtttttggaaatccggctcccgctttaggacagaccgtgtccacggaaaag
gcgcttgagattgccggagaaattcttccggaaggttattccgtttcgattaccggttcg
gccaaaaccgctaaagaatccggagagagtctgacgctcgctttggcgttcggaattcta
ctttcttatatgattctcgccagtcaattcaacagtttgaaacaacctctttatattctt
cttgcgatgcctttcagttttacgggagcgttagtcgctctttatgcgttcggtcagtcg
ttcaatatgtacagttttatcggactcattctccttttgggtttggtaaaaaagaactcg
attctgctcgtggagttcgtcaatcaggttcgaacgactgggaaaaacgtccgggaatcg
attcaagaaggttgcccgatccgtttgagacccgtgcttatgacctcgttcagttcgatt
gccgccgccattccacctgcgttggctctgggacccggggcggaaacgagaattccaatg
gctgtgacgattttaggaggaatgactctttccacactgattactcttttggttgttccc
gcggcgtattatctcggagaaaaggaaaaacgatga

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