Lachancea thermotolerans: KLTH0F01430g
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Entry
KLTH0F01430g CDS
T01117
Name
(RefSeq) trifunctional histidinol dehydrogenase/phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase
KO
K14152
phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:
3.6.1.31
3.5.4.19
1.1.1.23
]
Organism
lth
Lachancea thermotolerans
Pathway
lth00340
Histidine metabolism
lth01100
Metabolic pathways
lth01110
Biosynthesis of secondary metabolites
lth01230
Biosynthesis of amino acids
Module
lth_M00026
Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:
lth00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
KLTH0F01430g
Enzymes [BR:
lth01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.23 histidinol dehydrogenase
KLTH0F01430g
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.19 phosphoribosyl-AMP cyclohydrolase
KLTH0F01430g
3.6 Acting on acid anhydrides
3.6.1 In phosphorus-containing anhydrides
3.6.1.31 phosphoribosyl-ATP diphosphatase
KLTH0F01430g
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Gene cluster
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Motif
Pfam:
Histidinol_dh
PRA-CH
PRA-PH
Motif
Other DBs
NCBI-GeneID:
8292463
NCBI-ProteinID:
XP_002554272
UniProt:
C5DK34
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Position
F:complement(106971..109406)
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AA seq
811 aa
AA seq
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MGFPILPFFTSSEELKTVAGSKPYLGLTGQALLDLTKVSVDDAIAFIENNSAYKFVCGLL
GASNTLSDDDVVRLLNNGVSVLFLQDCSMAAPLVQLGVPKERLAVLEGATYTCNFGVVQK
FSTSQIVEASALSTDKLADALFSSLKTDRDDKLYTTLVVDTHERCLGLVYSSKESIKQAF
EQQVGVYYSRSRNEIWVKGLTSGNTQKLVNINIDCDGDALKFVVVQEGKKSDFCHLNTTS
CYGEFQQGLVGLEGLLRQRLENAPEKSYTRRLFSDPELLTAKIKEEAEELTEAADKKEVA
WEAADLFYFAMVKLVASGVSLDDVERNLHVKHLKITRRKGDAKEKFLQKKPSEESKAEAA
AETVDDGSISLNVVSDQDKKGVSEALSRPIQKTADIMHLVNPIVERVRNEGDKALLEFTQ
KFDGVKLDSPVLEAPFPKEYFEGLTDEMKEALDLSMENVRKFHEAQLQKETLEVVTQPGV
VCSRFPRPIEKVGLYIPGGTAVLPSTALMLGVPARVAECQEIVFASPPRKSDGKVSPEVV
YVAQKVGASKIVLAGGAQAVAAMAYGTESIPKVDKILGPGNQFVTAAKMYVQNDTQALCS
IDMPAGPSEVLVIADEKADADFVASDLLSQAEHGVDSQVILVGVALSEKKVAEIQDAVHR
QALELPRVDIVRKCIAHSSIILCDSYETAFDMSNDYAPEHLILQIENAQDYVKLVFNAGS
VFVGAYTPESCGDYSSGTNHTLPTYGYARQYSGVNTSTFQKFITSQVVNPQGLENIGRAV
MSVAKVEGLDAHRNAVKIRMQKLGLLPESFQ
NT seq
2436 nt
NT seq
+upstream
nt +downstream
nt
atggggttccctattctaccatttttcacttccagtgaggaactgaaaactgttgctggc
tccaaaccgtaccttggtcttacgggccaagcattattggacttgactaaggtttcggtc
gatgatgcaattgcgtttattgaaaacaactctgcttacaagtttgtgtgtggtctcctc
ggcgcaagcaacactttatctgatgatgatgttgtccgtctcctgaacaacggggtttcc
gttttgttcttgcaagactgcagcatggctgcacccttggttcagctaggcgtccccaaa
gaaagactagcggtcctcgaaggtgccacttacacttgcaatttcggagttgttcaaaaa
ttcagtaccagccagatcgtcgaggcatccgcgctctctactgataagctagctgatgcg
ttattctcaagcttgaagactgatcgtgatgacaaactgtacacaactcttgttgtggac
actcacgaacgttgtttagggctggtttattcatccaaagaatctattaagcaggctttc
gaacagcaagtcggcgtgtactactctcgctccagaaacgagatttgggtcaaaggcctc
acatctggtaacacgcaaaagttggttaacatcaacatagactgtgacggagatgcacta
aagtttgttgttgttcaagagggcaagaaatctgacttctgtcacctgaacactacctca
tgttacggtgagttccagcagggactggttgggcttgagggcttgttgcgtcaaaggctg
gagaacgctcctgaaaagtcttacacgcgcagactgttcagtgatcctgagcttcttact
gctaagataaaagaagaggctgaggagctaactgaggcggctgacaaaaaagaggtggcc
tgggaagctgctgatctattttactttgctatggtgaagttggttgctagcggcgtttct
cttgacgatgtcgagaggaacttgcatgtcaaacacttgaaaattacaagaagaaagggt
gacgctaaggagaaattcttgcagaaaaaaccatctgaggaatctaaggccgaggctgca
gctgagactgttgacgacggttctatcagcttaaatgttgtttctgaccaggacaaaaaa
ggggtttcagaagctttgagtaggcctatccagaagacggcggacatcatgcacctggtt
aatcctattgtggaaagagtacgcaatgaaggtgacaaggctctgctcgaatttactcag
aagtttgacggtgttaaacttgactctcctgttctagaggcgcccttcccaaaagagtac
tttgaaggattaaccgatgaaatgaaagaagctctggacttgtcaatggaaaatgttcgc
aagttccacgaagctcaactgcaaaaagaaactctggaagtggtcactcaacctggtgtt
gtgtgctcacgtttccctcgccctattgaaaaagtcggcctatacattccaggaggtact
gccgtgcttcctagtaccgctctgatgttgggtgtaccagctcgtgttgcagaatgtcag
gaaattgttttcgcctcccctccacgcaagtctgatggcaaggtgtccccagaggtcgtc
tatgtggctcagaaggtgggtgcgtccaagatcgtcctcgctggtggcgcacaagctgtt
gccgcgatggcctacggtaccgaatcgattcctaaggttgataaaattcttggtccaggc
aaccaattcgtcacagctgctaagatgtatgtgcaaaacgatacacaagcgctgtgttcc
attgacatgcctgctggacctagtgaggttctagtgattgcagatgagaaggctgatgct
gattttgtggcttccgatttgctgtcgcaggccgagcacggcgtggactcgcaagtgatt
ttggtgggtgtcgccttgagcgaaaagaaggtcgctgaaatccaagacgcagttcaccgc
caagccttggagcttcctcgtgttgacattgttcgcaaatgtatcgcacacagttcgatc
attctctgcgactcttacgagaccgctttcgacatgtctaatgactacgcaccagagcac
ttgattttgcagatcgagaatgctcaagattatgtcaagttggtgttcaatgctggtagt
gttttcgttggcgcttacacccccgagtcctgtggtgactactccagtggtacgaaccac
actctgcctacctatgggtacgccagacagtacagcggtgtcaacacctccactttccag
aaatttattacttctcaagttgtgaacccacaaggtctggagaatatcggccgcgctgtt
atgagcgtagctaaggttgaaggcctggatgctcaccgtaatgcggtcaaaattagaatg
cagaagctaggcttgctgccagagagcttccagtaa
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