KEGG   Limnobacter thiooxidans: RGQ30_22810
Entry
RGQ30_22810       CDS       T09704                                 
Symbol
acrB
Name
(GenBank) efflux RND transporter permease AcrB
  KO
K18138  multidrug efflux pump
Organism
lto  Limnobacter thiooxidans
Pathway
lto01501  beta-Lactam resistance
lto01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:lto00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    RGQ30_22810 (acrB)
   01503 Cationic antimicrobial peptide (CAMP) resistance
    RGQ30_22810 (acrB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:lto02000]
    RGQ30_22810 (acrB)
   01504 Antimicrobial resistance genes [BR:lto01504]
    RGQ30_22810 (acrB)
Transporters [BR:lto02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   RGQ30_22810 (acrB)
Antimicrobial resistance genes [BR:lto01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    RGQ30_22810 (acrB)
SSDB
Motif
Pfam: ACR_tran SecD_SecF_C
Other DBs
NCBI-ProteinID: BET26780
UniProt: A0AA86J806
LinkDB
Position
2536014..2539148
AA seq 1044 aa
MSRFFIDRPIFAWVIAIVIMLAGVLAITSLPVAQYPAIAPPAVTISATYPGASAETLQDS
VTQVIEQRMTGLDGLRYMKSTSDSTGRLRLELTFEPGTNPDIAQVQVQNKLSLATALLPS
AVQRQGIQVTKSSAGYLLVIAFTAVDGAFTSTELADFITSNVQDTMSRVNGVGEVQVFGS
PYAMRIWMNPEKMSQFKITPGDIRSAVQAQNAQVSAGELGAAPAVKGQSLTATITAQSLL
ETPEDFQQIVLRTTADGASVRLKDVARIDYGSENYTTLPRWNGRNASGIGIRLASGANAL
DTAESVIKEMERITPLIPEGMEWDIAYDTTPFVKISIEGVVKTLIEAIILVFLVMYLFLQ
NFRATLIPTIAVPVVLLGTFAVLSAFGFSINTLTMFAMVLAIGLLVDDAIVVVENVERVM
AEEGLSPLEATRKSMDQITGALIGIGLVLSAVFVPMAFFPGSAGVIYKQFSITIVSAMAL
SVIVALVLTPALCATMLKPIEKGHSHEKKGFFGWFNRKFDASSARYQGVVGKMLHKSGRY
LIIYGGLLAVTAFMFTRLPTSFLPDEDQGVFFTQVQLPAGATQEQTLAVLAKMEDYFLNK
EGANVKSLFTVAGFSFSGTGQNSGIGFVRLRDWGERPGKENSAAGIVQRASKEFASWPEA
QAFAFAPPPIRELGNALGFNLFIQDRTGLGRDALLQARNTMIAEAAKNPVLTGVRPNAQE
NTPQYQLDIDNAKAGALGVSVAEISDTLTSAWGGSFINDFLDRGRVKRVYMQADAPYRML
PEDLNRWYVRNGQGEMVPFGNFASAQWTMGSPRLERYNGLPAVEIQGQAAPGMSSGDAMN
AMEDIAANLPEGLGIEWTGLSYEERQSGSQAPLLYALSLLIVFLCLAALYESWSIPFAVM
LIVPLGVVGALVAASSRGLANDVYFQVALLTTVGLSAKNAILIVEFAKEEYEKGLDLLDA
TLVAVRMRLRPILMTSLAFGLGVVPLAISTGAGSGSQNAIGTGVLGGTISATVLGIFFVP
LFFVVVTQMFSKKRAEKKAATVGE
NT seq 3135 nt   +upstreamnt  +downstreamnt
atgtcccgattttttattgatcgcccgatttttgcctgggtcatcgccattgtcatcatg
ctggccggtgtgctggccattaccagcttgccggtggcacagtaccccgcgattgctcca
ccggcagtgaccatttccgccacctaccccggtgcgtctgctgaaacacttcaggactca
gttactcaggtgattgaacagcgcatgacgggcctggatggcctgcgttacatgaagtcc
accagcgactccacgggcaggcttcgccttgaactgacgtttgaacccggcaccaacccc
gacattgcacaggtgcaggttcagaacaaactgagcctggccaccgccctgttgcccagt
gccgtgcaacgccagggtattcaggtgacaaaaagttcggcgggttacctgctggtcatt
gcatttaccgcagtggatggggcctttacatccaccgaactggccgacttcattacctcc
aatgttcaagacaccatgagccgtgtcaacggtgtgggcgaggtgcaggtgttcggtagc
ccgtatgccatgcgcatctggatgaacccggagaaaatgagccagttcaagatcaccccg
ggtgatattcgcagtgcagttcaagcccagaatgcgcaggtttcagccggtgaactgggt
gcggcaccagccgtgaaagggcaatcactgacagccaccatcaccgcgcaaagtctgctg
gaaaccccggaagattttcaacaaattgtattgagaaccaccgccgatggggcaagcgtg
cgcctgaaagatgtggcccgcattgactacggcagtgaaaactacaccaccctgccccgc
tggaatggccgaaatgcctcgggtattggtatccgcctggcttccggtgccaatgcgctg
gacacggctgaatcggtgatcaaggaaatggagcgcatcacgccgctgattccggaaggc
atggaatgggacatcgcctacgacaccaccccgtttgtaaaaatttcaattgaaggcgtc
gtgaaaacgctgatcgaggccatcatcctggtgttcctggtgatgtacctgttcttgcag
aatttccgcgccacgctgatcccaacgattgcggtacccgtggtgttgctgggtaccttt
gccgtgctgtccgcattcggattttcaatcaacacattgaccatgtttgccatggtgctg
gccattggcctgctggtggacgacgccattgtggtggttgaaaacgtggaacgcgtgatg
gcagaagaaggcctctcaccactggaagccacccgcaaatccatggaccagatcaccggc
gcgttgatcggtattggattggtactttctgccgtgtttgtacccatggcatttttcccg
ggctcggctggtgtcatttacaagcagttttccatcaccattgtgtcagccatggcgctg
tcggtgattgtggctttggtgctcacgcccgccctgtgtgccaccatgttgaagcccatt
gaaaaaggccacagccacgaaaagaaaggattctttggctggttcaaccgaaagttcgat
gccagcagcgcgcgttatcaaggtgtggttggcaaaatgctgcacaagtcaggccgctac
ctgatcatctatggtggcttgctggcggtgactgccttcatgtttacacgcctgcccacg
tccttcttgcctgatgaagaccaaggcgtgtttttcacccaggttcaactgcctgctggc
gcaacccaggaacaaacgctggccgtgctcgccaagatggaagactacttcttgaacaag
gaaggtgcaaacgtgaagtccctgttcaccgtggccggtttcagcttctcgggcactggc
cagaattcaggcattggctttgttcgcttgcgcgactggggcgaacggcctggcaaggaa
aactcggccgctggtattgttcagcgtgcatcaaaagagtttgcaagctggccagaagcg
caggcctttgcctttgctccacccccaattcgggaactgggcaatgcgctgggctttaac
ctgttcattcaggaccgtaccgggctgggtcgcgacgccttgctgcaagccagaaacacc
atgattgccgaagcggcgaaaaacccggttctcactggcgttcgacccaacgcacaggaa
aacacaccgcaataccaactggacatcgacaacgccaaggccggtgcgctgggtgtttcc
gtggctgaaatcagcgacaccctgacatcagcctggggcggcagcttcatcaatgacttc
ctggacaggggccgtgtgaaacgtgtttacatgcaagccgacgcgccttaccgcatgctg
cctgaagacctgaaccgctggtatgtgcgcaatggtcagggtgaaatggtgccctttggt
aactttgcatcggcgcaatggaccatgggctcgccccgactggaacgctacaacggtctg
cctgccgtggaaattcaaggacaggccgcaccaggcatgagttcgggcgacgccatgaat
gcgatggaagacattgcagccaacttgcctgaaggcttgggcattgaatggactggcctg
tcgtatgaagaaaggcaatccggctcgcaggcccccttgctgtacgcgctgtcgctgttg
attgtgttcctgtgcctggctgccttgtatgaaagctggtccattccgtttgcggtcatg
ctgattgtgccgctgggtgtggtgggtgcactggtggcagccagcagccgcggtttggcc
aacgacgtgtacttccaggtggcactgctgaccaccgtcggtctgtctgcgaaaaacgcc
attctgattgtggaatttgccaaggaagaatacgagaaaggcctagatttgctggacgcc
acactggtggctgtgcgcatgcgtttgcgcccgatcctgatgacttcgctggcgtttggt
ttgggtgtagtgcccttggccatttcaacgggcgcaggttcaggcagccagaacgcgatt
ggtaccggcgtgttgggtggcaccatttctgccacagttctgggtattttctttgtgccc
ctgttcttcgtggtggtgacccagatgttcagcaaaaagcgggcggaaaagaaagctgcc
accgtgggggaatga

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