Lipotes vexillifer (Yangtze River dolphin): 103086619
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Entry
103086619 CDS
T03090
Symbol
HSD11B1
Name
(RefSeq) corticosteroid 11-beta-dehydrogenase isozyme 1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
lve
Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve00140
Steroid hormone biosynthesis
lve00980
Metabolism of xenobiotics by cytochrome P450
lve01100
Metabolic pathways
lve05204
Chemical carcinogenesis - DNA adducts
Module
lve_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
lve00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
103086619 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
103086619 (HSD11B1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
103086619 (HSD11B1)
Enzymes [BR:
lve01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
103086619 (HSD11B1)
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Ortholog
Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
THF_DHG_CYH_C
2-Hacid_dh_C
Pyr_redox_2
NAD_binding_2
Pyr_redox_3
Shikimate_DH
Methyltransf_25
FMO-like
Pyr_redox
Motif
Other DBs
NCBI-GeneID:
103086619
NCBI-ProteinID:
XP_007451625
UniProt:
A0A340WXP6
LinkDB
All DBs
Position
Unknown
AA seq
294 aa
AA seq
DB search
MAFMKKYVLPILGIFLAYYYYSAKEEFRPEMLRGKRVIVTGASKGIGREMAYHLARMGAH
VVVTARSEEALKKVVSHCLELGASSAHYVAGTMENMTFAEEFVAKAGKLMGGLDMLILNH
ITNTNNPMTVFIDDIDHVRKNMEVNFLSYVVLSGAAMPMLKQSNGSIVVVSSIAGKTANP
LIAAYSASKFALDGFFSSIRAEYAVTNVNVSITLCILGLIDTETAMTGTAGIYNAEASPK
EECALEIIKGGALRQKEVYYDSSVLTPFLLGNPGRKIMEFLSLRNYNMEIFINN
NT seq
885 nt
NT seq
+upstream
nt +downstream
nt
atggcttttatgaagaaatacgtcctccccattctggggatcttcttggcctactactac
tattctgcgaaggaggaattcagaccagagatgcttcgaggaaaaagagtgattgtcaca
ggggccagcaaggggattggaagagaaatggcctatcatctggcgagaatgggagcccat
gtggtagtgacagcgaggtcagaagaagctctaaagaaggtggtatcccactgcctggag
ctcggtgcatcctcggcgcactatgttgctggcaccatggagaacatgaccttcgcagag
gaatttgttgccaaagctggaaaactcatgggcggactagacatgctcattctcaaccac
atcaccaacaccaacaatcctatgactgtatttattgatgacattgaccacgtgcgcaaa
aacatggaggtcaacttcctgagttatgtggtcctgagcggggccgccatgcccatgctg
aagcagagcaacgggagcattgtggttgtctcctcgatagctgggaaaacagctaatccc
cttattgctgcctattctgcaagcaagtttgctctggatgggttcttctcttctatcagg
gcggaatatgcagtgaccaatgtcaatgtgtcgatcaccctctgtatccttggcctcata
gacacagaaacagccatgacaggaactgctgggatatacaatgcagaagcatctccaaag
gaagaatgtgccctggagattatcaaagggggagctctgcgccaaaaagaagtatattat
gacagttcggtcttgactcctttcctgctgggaaatccagggaggaagatcatggaattt
ctctccttacgaaattataatatggaaatatttataaacaactag
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