Leptonychotes weddellii (Weddell seal): 102727001
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Entry
102727001 CDS
T08708
Symbol
HSD11B1
Name
(RefSeq) corticosteroid 11-beta-dehydrogenase isozyme 1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
lww
Leptonychotes weddellii (Weddell seal)
Pathway
lww00140
Steroid hormone biosynthesis
lww00980
Metabolism of xenobiotics by cytochrome P450
lww01100
Metabolic pathways
lww05204
Chemical carcinogenesis - DNA adducts
Module
lww_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
lww00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
102727001 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
102727001 (HSD11B1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
102727001 (HSD11B1)
Enzymes [BR:
lww01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
102727001 (HSD11B1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
THF_DHG_CYH_C
Shikimate_DH
2-Hacid_dh_C
NAD_binding_2
Pyr_redox_3
Methyltransf_25
NAD_binding_7
Motif
Other DBs
NCBI-GeneID:
102727001
NCBI-ProteinID:
XP_006733685
UniProt:
A0A2U3XQG5
LinkDB
All DBs
Position
Unknown
AA seq
184 aa
AA seq
DB search
MAFMKKYLPPILVFFLAYYYYSANEEFRPEMLQGKKVIVTGASKGIGEQMAYHLAKMGAH
VVVTARSKETLKKVVSHCLELGAASAHYIAGSMENMTFAEQFVAQAGKLMGGLDMLILNH
ITNTSMNLFSGDIHLVRRSMEVNFLSYVVLSVAALPMLKQSNGSIVVISSKAGKECASSL
ARET
NT seq
555 nt
NT seq
+upstream
nt +downstream
nt
atggcttttatgaaaaaatatctcccacccattctggtgttcttcttggcctactactac
tattctgcaaatgaggaattcagaccagagatgctccaaggaaagaaagtgattgtcaca
ggggccagcaaggggatcggagaacagatggcctatcatctggcgaaaatgggagcccat
gtggtggtgacagcaaggtctaaagaaactctaaagaaggtggtatcccactgcctggag
cttggagcagcctcagcacactacattgctggctccatggagaatatgaccttcgcagag
caatttgttgcccaagctggaaagctcatggggggactagacatgctcattctcaaccac
atcaccaacacttctatgaatctatttagtggtgatatccaccttgtgcgcagaagcatg
gaagtcaacttcctcagttacgtggtcctgagcgttgccgccttgcccatgctgaagcag
agcaacgggagcattgtcgtcatctcctcgaaggctggcaaagagtgtgcttcatctttg
gctagagaaacgtaa
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