Leptonychotes weddellii (Weddell seal): 102727785
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Entry
102727785 CDS
T08708
Symbol
JAK3
Name
(RefSeq) tyrosine-protein kinase JAK3 isoform X1
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
lww
Leptonychotes weddellii (Weddell seal)
Pathway
lww04062
Chemokine signaling pathway
lww04151
PI3K-Akt signaling pathway
lww04217
Necroptosis
lww04550
Signaling pathways regulating pluripotency of stem cells
lww04630
JAK-STAT signaling pathway
lww04658
Th1 and Th2 cell differentiation
lww04659
Th17 cell differentiation
lww05161
Hepatitis B
lww05162
Measles
lww05166
Human T-cell leukemia virus 1 infection
lww05169
Epstein-Barr virus infection
lww05200
Pathways in cancer
lww05203
Viral carcinogenesis
lww05223
Non-small cell lung cancer
lww05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
lww00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
102727785 (JAK3)
04151 PI3K-Akt signaling pathway
102727785 (JAK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
102727785 (JAK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
102727785 (JAK3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
102727785 (JAK3)
04659 Th17 cell differentiation
102727785 (JAK3)
04062 Chemokine signaling pathway
102727785 (JAK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102727785 (JAK3)
05203 Viral carcinogenesis
102727785 (JAK3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
102727785 (JAK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
102727785 (JAK3)
05161 Hepatitis B
102727785 (JAK3)
05162 Measles
102727785 (JAK3)
05169 Epstein-Barr virus infection
102727785 (JAK3)
09163 Immune disease
05340 Primary immunodeficiency
102727785 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lww01001
]
102727785 (JAK3)
Enzymes [BR:
lww01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
102727785 (JAK3)
Protein kinases [BR:
lww01001
]
Non-receptor tyrosine kinases
JAK family [OT]
102727785 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
SH2_1
FERM_F1
Jak1_Phl
Kdo
ABC1
Kinase-like
FERM_C_FAK1
FERM_M
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
102727785
NCBI-ProteinID:
XP_006749641
UniProt:
A0A2U3Z0Y0
LinkDB
All DBs
Position
Unknown
AA seq
1104 aa
AA seq
DB search
MAPPSEETPLIPQRSCSLSSSEAGALHVLLPPRGPGPPQRLSFSFGDHSAEELCVWAAKA
SGILPVYHSLFALATEDLSCWFPPSHVFSVEDSGTQVLVYRLRFYFPNWFGLEKCHRFGL
RKDLASAILDLPVLEHLFAQHRNDLVSGRLPVGLSLKEQGECLSLAVLDLARMAREQAQQ
PEELLKTVSYKVCLPPDLRDLIQGLRFVTRKRIRRTVRRALRRVTACQADRHSLMAKYIM
DLERLDPARAVETFLVSLPGAAGGQDVQGLLRVAGDTGIAWSPGGQEALQPFCDFPEIVD
ISVKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPAALSFVALVDGYFRLTSDSRHFFC
KEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSLPGSYVLRRSPQDFDCFLLTVCVQTP
LGPDYKGCLIRCDPTGTLSLAGLGRPHSSLRELLAACWDGGLHVDGVALNLTFCCTPKPK
EKSNLIVVRRDCSTPTSSPVRLHSQCQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCR
HEVVEGEVRETEVLLKVMDAKHKNCMESFLEAASLMSQVSYQHLVLLHGVCMAGDSIMVQ
EFVHLGALDTYLRKSGHLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKVLLAREGA
DGNLPFIKLSDPGVSPSVLSRDMLTDRIPWVAPECLQEAWTLGLEADKWGFGATVWEVFS
GIPMPISTLDPAKKLQFYEERQHLPAPKWTELAILIQQCMAYEPGQRPSFRAIIRDLNSL
ITSDYELLSDPTPGALAPRDGLWNGAQLYAYQDPTIFEERHLKYISQLGKGNFGSVELCR
YDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRL
VMEYLPSGCLRDFLQRHRARLAASRLLLYASQICKGMEYLGSRRCVHRDLAARNILVESE
THVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYEL
FTYGNKSCSPSAEFLRMMGCDGDVPALCCLLELLAEGQRLPAPPACPGEVHELMKLCWAS
SPQDRPTFSALGPQLDALWSESRS
NT seq
3315 nt
NT seq
+upstream
nt +downstream
nt
atggcgcctccaagcgaggagacacccttgattcctcagcgctcctgcagcctctcgtct
tcagaagctggtgccctgcacgtgctgctgccccctcggggccctggacccccacagcgc
ttatccttctcctttggggaccattcagctgaagagctgtgtgtttgggctgctaaggcc
agtggcatcctgcctgtgtaccactccctctttgctctggccacggaggacctgtcctgc
tggttccccccaagccacgtcttctccgtggaggactcgggcacccaagttctggtctac
aggctccgcttttacttccccaactggtttgggctagagaagtgccaccgcttcgggcta
cgaaaggacttggccagcgccatccttgacctaccagtcctggagcacctcttcgcccag
caccggaatgacctggtgagcggccgcctccccgtgggcctcagtctcaaggagcagggt
gaatgtctcagcctggcggtgctggacctggcccggatggcccgcgagcaggctcagcag
cctgaggagctgctgaaaactgtcagctacaaggtctgcctgcctcccgacctgcgcgac
ctgatccagggcctgaggttcgtgacgcggaagcgcatccgcaggactgtgcgtcgggcc
ctgcgccgcgtgaccgcctgccaggctgacaggcactcgctcatggccaaatacatcatg
gacctggagaggctcgacccggccagggcggtagagaccttcctcgtgagcctccccggg
gctgctggtggtcaggatgtgcaggggctgctccgagtggctggcgacaccggcatcgcc
tggagtccaggaggacaagaggccctccagcccttctgcgactttccagaaattgtggac
atcagcgtcaagcaggctccgcgtgttggcccggccggggagcaccgcctggtcaccgtc
accaggacagacaaccagatcctggaggccgagttcccggggctgcccgccgcgttgtcc
ttcgtggcgctagtcgacggctacttccggctgacctccgactcccggcacttcttctgc
aaggaggttgcgccgccgcggctgctggaggaggtggccgagcagtgccacggccccatc
accctggattttgccatcaacaagctcaagactgggggctcacttcctggctcctacgtt
ctccgccgcagtccccaggattttgattgcttcctcctcactgtctgtgtccagaccccc
ctgggtcctgattacaagggctgcctcatccggtgtgaccccacgggaaccttgtccctg
gctggccttggccgtccccacagcagtctccgagagctcttggcagcctgctgggatggt
gggctgcacgtggacggggttgcgctgaacctcaccttctgctgcacccccaaacccaaa
gaaaagtccaacctgattgtggtgcggagggattgcagcacacccacatcatcccctgtt
cggctccattcccaatgccagctgagtcagatgacatttcacaagatccctgctgacagc
ctggagtggcatgagaacctgggtcatgggtccttcaccaagatttaccgaggttgtcgc
cacgaggtcgtggagggggaggtccgggagacagaggtgctgctcaaagtgatggatgcc
aagcataaaaactgcatggagtcatttctggaagcagcgagtttgatgagccaagtgtca
taccagcatctcgtgttgctccacggcgtgtgcatggctggagacagtatcatggtgcag
gaatttgtacacctgggagcgctggacacctacctgcgcaagtctggccacctggtgcca
gccagctggaagctgcaggtgatcaaacagctggcctatgccctcaactatctggaagac
aaaggcctcccccatggcaatgtctcagcccggaaggtgctcctggctcgcgaaggggct
gatgggaacctgcccttcatcaagctgagtgaccctggtgtcagcccctctgtgctaagc
cgggacatgctcactgacaggatcccctgggtggcccccgagtgtctccaggaggcctgg
acactcggcttggaagctgacaagtggggttttggtgccacagtctgggaggtgttcagt
gggatcccgatgcccatcagcaccctggatcccgccaagaagctccagttttatgaggaa
cggcagcacctgcctgcccccaagtggacggagttggccatactgatccagcagtgcatg
gcctatgagccaggccagagaccctccttccgggccatcatccgtgacctgaacagcctc
atcacttcagattacgagctcctctcagaccccacgcccggcgccttggcgccccgtgat
gggctgtggaatggcgcccagctctacgcctaccaggaccctaccatttttgaggagaga
cacctcaagtacatctcacagctgggcaagggcaacttcggcagcgtggaactgtgccgc
tatgacccgctgggcgacaacacgggcgccctagtggcagtgaagcagctgcagcacagc
gggccagaccagcagagggacttccagagggagatccagatcctcaaagccctccacagc
gacttcattgtcaagtaccgcggagtcagctatggcccaggccgccagagcctgcggctg
gtgatggagtacctgcccagcggctgcctgcgcgacttcctgcagcggcatcgcgcgcgc
ctcgccgccagccgcctgctcctttacgcctcgcagatctgcaagggcatggagtacctg
ggctcccgccgctgtgtgcaccgcgacctggcagcgcgtaacatcctggtggagagcgag
acgcacgtcaagatcgccgactttggcctcgccaagctgctgccgctcgacaaagactac
tacgtggtccgcgagcccggccagagccccatcttctggtacgccccggagtccctctct
gacaatatcttctcgcgccagtccgacgtctggagcttcggggtcgtcctgtacgagctt
ttcacctacggcaacaagagttgcagcccctcagccgagttcctgcggatgatgggatgt
gatggagatgtcccggccctctgctgcctcctggagctgctggctgagggccagaggctg
cctgcacctcctgcctgccctggtgaggttcatgagctcatgaagctgtgctgggcctct
agcccgcaagaccggccaacattcagtgccctgggcccccagctggatgcactatggagt
gaaagccggagctag
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