Leptonychotes weddellii (Weddell seal): 102728739 Help Entry 102728739         CDS       T08708                                  Symbol TRAF6 Name (RefSeq) TNF receptor-associated factor 6   KO K03175   TNF receptor-associated factor 6 [EC:2.3.2.27] Organism lww  Leptonychotes weddellii (Weddell seal) Pathway lww04010   MAPK signaling pathway lww04064   NF-kappa B signaling pathway lww04120   Ubiquitin mediated proteolysis lww04140   Autophagy - animal lww04144   Endocytosis lww04380   Osteoclast differentiation lww04620   Toll-like receptor signaling pathway lww04621   NOD-like receptor signaling pathway lww04622   RIG-I-like receptor signaling pathway lww04657   IL-17 signaling pathway lww04722   Neurotrophin signaling pathway lww04936   Alcoholic liver disease lww05132   Salmonella infection lww05133   Pertussis lww05135   Yersinia infection lww05140   Leishmaniasis lww05142   Chagas disease lww05145   Toxoplasmosis lww05152   Tuberculosis lww05160   Hepatitis C lww05161   Hepatitis B lww05162   Measles lww05168   Herpes simplex virus 1 infection lww05169   Epstein-Barr virus infection lww05170   Human immunodeficiency virus 1 infection lww05171   Coronavirus disease - COVID-19 lww05200   Pathways in cancer lww05222   Small cell lung cancer lww05235   PD-L1 expression and PD-1 checkpoint pathway in cancer lww05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:lww00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     102728739 (TRAF6)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     102728739 (TRAF6)    04064 NF-kappa B signaling pathway     102728739 (TRAF6)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     102728739 (TRAF6)    04140 Autophagy - animal     102728739 (TRAF6)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     102728739 (TRAF6)    04621 NOD-like receptor signaling pathway     102728739 (TRAF6)    04622 RIG-I-like receptor signaling pathway     102728739 (TRAF6)    04657 IL-17 signaling pathway     102728739 (TRAF6)   09156 Nervous system    04722 Neurotrophin signaling pathway     102728739 (TRAF6)   09158 Development and regeneration    04380 Osteoclast differentiation     102728739 (TRAF6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102728739 (TRAF6)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     102728739 (TRAF6)   09162 Cancer: specific types    05222 Small cell lung cancer     102728739 (TRAF6)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     102728739 (TRAF6)    05161 Hepatitis B     102728739 (TRAF6)    05160 Hepatitis C     102728739 (TRAF6)    05171 Coronavirus disease - COVID-19     102728739 (TRAF6)    05162 Measles     102728739 (TRAF6)    05168 Herpes simplex virus 1 infection     102728739 (TRAF6)    05169 Epstein-Barr virus infection     102728739 (TRAF6)   09171 Infectious disease: bacterial    05132 Salmonella infection     102728739 (TRAF6)    05135 Yersinia infection     102728739 (TRAF6)    05133 Pertussis     102728739 (TRAF6)    05152 Tuberculosis     102728739 (TRAF6)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     102728739 (TRAF6)    05140 Leishmaniasis     102728739 (TRAF6)    05142 Chagas disease     102728739 (TRAF6)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102728739 (TRAF6)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     102728739 (TRAF6)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:lww04131]     102728739 (TRAF6)    04121 Ubiquitin system [BR:lww04121]     102728739 (TRAF6) Enzymes [BR:lww01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      102728739 (TRAF6) Membrane trafficking [BR:lww04131]  Endocytosis   Clathrin-mediated endocytosis    Ubiquitin E3 ligases     102728739 (TRAF6) Ubiquitin system [BR:lww04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    TRAF proteins     102728739 (TRAF6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TRAF-mep_MATH MATH_2 zf-TRAF TRAF6_Z2 zf-C3HC4_2 zf-C3HC4 zf-RING_UBOX zf-RING_2 zf-C3HC4_3 zf-C3HC4_4 zf-TRAF_2 zf-RING_5 Sina_ZnF SlyX TRAF3_RING RING_XB3-XBAT31 DUF16 U-box zf-RING_11 DUF4455 DUF3450 Spc29 PspA_IM30 DUF7310 Med21 DUF6271 Laminin_II UPF0242 ATG16 DUF1664 TMF_DNA_bd Motif Other DBs NCBI-GeneID:  102728739 NCBI-ProteinID:  XP_006736642 UniProt:  A0A2U3XYU7 LinkDB All DBs Position Unknown AA seq 541 aa AA seqDB search MSLLNCENSCGSGQSEGDCCGAMAGPCSAAAKDDSVGGTAGPGNLSSSFLEEIQGYDVEF DPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPD NFAKREILSLMVKCPNEGCLHKMELRHLEDHQVHCEFALMNCPQCQRPFQKCQLNIHILK ECPRRQVSCMNCAALMAFEDKEIHDQNCPLANVICEYCNTMLIREQMPNHYDLDCPTAPI PCTFSTFGCHVKMQRNHLARHLQENTQSHMRMLAQAVQGLSLALAPVPQRDMAPYDSSSV SRVSTPCHPEVHNFQETIQQLEGRLVRQDHQIRELTAKMETQSMYVNELKRTIRTLEDKV AEIEAQQCNGIYIWKIGNFGMHLKSQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQ RCANYISLFVHTMQGEYDSHLPWPFQGTIRLAILDQSEAPVRQNHEEIMDAKPELLAFQR PTIPRNPKGFGYVTFMHLDALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDSG T NT seq 1626 nt NT seq  +upstreamnt  +downstreamnt atgagtctgctaaactgtgagaacagctgtggatccggccagtccgagggtgactgctgt ggtgctatggccggcccgtgtagcgctgcagcaaaagatgacagtgtgggtggaaccgcc ggcccggggaacctgtccagctcctttctggaagagatccaggggtatgatgtggagttt gacccacccctggaaagcaagtatgaatgccccatctgcttgatggcgttaagggaagca gtgcaaacaccatgtggtcacaggttctgcaaagcttgcatcatcaaatcaataagggat gctggtcacaaatgtccagttgacaatgaaatattgctggaaaatcaactatttcctgac aattttgcaaaacgagagattctttctttgatggtgaagtgtccaaatgaaggttgtttg cacaagatggaactgaggcatcttgaggatcaccaagtacattgtgagtttgctctcatg aattgtccccagtgccaacgtcccttccaaaaatgccaacttaatattcacattcttaag gagtgcccgaggagacaggtttcttgcatgaactgtgctgcgttgatggcatttgaagat aaagagatccatgaccagaactgtcctttggcaaatgtcatctgtgaatactgcaatact atgctcatcagagaacagatgcctaatcactatgatctagactgtccgacagccccaatt ccatgcacattcagtacttttggttgccatgtaaagatgcagaggaatcacttggcacgc cacctacaagagaatacccagtcgcacatgagaatgttggctcaggccgttcagggttta agccttgctttagctcctgtacctcagcgtgatatggcgccatacgattcttcctctgtg tcccgggtctccactccgtgtcaccccgaggtccataatttccaagaaaccattcagcag ttagagggtcgccttgtaagacaagaccatcaaatccgagagctaactgctaaaatggaa actcagagcatgtatgtaaatgagctcaaacgaaccattcgaacccttgaagacaaagtt gctgaaatagaagcgcagcagtgcaacgggatctacatctggaagattggcaactttggg atgcatttgaaatctcaggaagaggagaaacctgttgtcattcacagccctggattctac acgggcaaacctggctacaaactgtgcatgcgcctgcacctccagttaccaactgctcag cgctgtgctaattatatatccctctttgtccacacaatgcagggagagtatgacagccac ctgccttggcccttccagggtacaatacgccttgcaattcttgatcagtctgaagcgcct gtaaggcagaaccatgaagagatcatggatgccaaaccagagctgcttgccttccagaga cccacaatcccacggaacccaaaaggttttggctatgtgacttttatgcacctggatgcc ctaagacaaagaaccttcattaaggatgatactttgttagtacgctgtgaggtctctacc cgctttgacatgggcagtctccggagggagggttttcagccacgaagtactgattcaggg acatag

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