Leptonychotes weddellii (Weddell seal): 102733005 Help Entry 102733005         CDS       T08708                                  Name (RefSeq) adenylate cyclase type 8-like   KO K08048   adenylate cyclase 8 [EC:4.6.1.1] Organism lww  Leptonychotes weddellii (Weddell seal) Pathway lww00230   Purine metabolism lww01100   Metabolic pathways lww01522   Endocrine resistance lww04015   Rap1 signaling pathway lww04020   Calcium signaling pathway lww04022   cGMP-PKG signaling pathway lww04024   cAMP signaling pathway lww04062   Chemokine signaling pathway lww04072   Phospholipase D signaling pathway lww04081   Hormone signaling lww04082   Neuroactive ligand signaling lww04114   Oocyte meiosis lww04211   Longevity regulating pathway lww04213   Longevity regulating pathway - multiple species lww04261   Adrenergic signaling in cardiomyocytes lww04270   Vascular smooth muscle contraction lww04371   Apelin signaling pathway lww04540   Gap junction lww04611   Platelet activation lww04713   Circadian entrainment lww04714   Thermogenesis lww04720   Long-term potentiation lww04723   Retrograde endocannabinoid signaling lww04724   Glutamatergic synapse lww04725   Cholinergic synapse lww04727   GABAergic synapse lww04742   Taste transduction lww04750   Inflammatory mediator regulation of TRP channels lww04911   Insulin secretion lww04912   GnRH signaling pathway lww04913   Ovarian steroidogenesis lww04914   Progesterone-mediated oocyte maturation lww04915   Estrogen signaling pathway lww04916   Melanogenesis lww04918   Thyroid hormone synthesis lww04921   Oxytocin signaling pathway lww04923   Regulation of lipolysis in adipocytes lww04925   Aldosterone synthesis and secretion lww04926   Relaxin signaling pathway lww04927   Cortisol synthesis and secretion lww04928   Parathyroid hormone synthesis, secretion and action lww04934   Cushing syndrome lww04935   Growth hormone synthesis, secretion and action lww04970   Salivary secretion lww04971   Gastric acid secretion lww04972   Pancreatic secretion lww04976   Bile secretion lww05032   Morphine addiction lww05163   Human cytomegalovirus infection lww05166   Human T-cell leukemia virus 1 infection lww05200   Pathways in cancer lww05207   Chemical carcinogenesis - receptor activation lww05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lww00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102733005  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102733005    04371 Apelin signaling pathway     102733005    04020 Calcium signaling pathway     102733005    04072 Phospholipase D signaling pathway     102733005    04024 cAMP signaling pathway     102733005    04022 cGMP-PKG signaling pathway     102733005   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102733005    04081 Hormone signaling     102733005  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102733005   09144 Cellular community - eukaryotes    04540 Gap junction     102733005  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102733005    04062 Chemokine signaling pathway     102733005   09152 Endocrine system    04911 Insulin secretion     102733005    04923 Regulation of lipolysis in adipocytes     102733005    04912 GnRH signaling pathway     102733005    04913 Ovarian steroidogenesis     102733005    04915 Estrogen signaling pathway     102733005    04914 Progesterone-mediated oocyte maturation     102733005    04921 Oxytocin signaling pathway     102733005    04926 Relaxin signaling pathway     102733005    04935 Growth hormone synthesis, secretion and action     102733005    04918 Thyroid hormone synthesis     102733005    04928 Parathyroid hormone synthesis, secretion and action     102733005    04916 Melanogenesis     102733005    04925 Aldosterone synthesis and secretion     102733005    04927 Cortisol synthesis and secretion     102733005   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102733005    04270 Vascular smooth muscle contraction     102733005   09154 Digestive system    04970 Salivary secretion     102733005    04971 Gastric acid secretion     102733005    04972 Pancreatic secretion     102733005    04976 Bile secretion     102733005   09156 Nervous system    04724 Glutamatergic synapse     102733005    04727 GABAergic synapse     102733005    04725 Cholinergic synapse     102733005    04720 Long-term potentiation     102733005    04723 Retrograde endocannabinoid signaling     102733005   09157 Sensory system    04742 Taste transduction     102733005    04750 Inflammatory mediator regulation of TRP channels     102733005   09149 Aging    04211 Longevity regulating pathway     102733005    04213 Longevity regulating pathway - multiple species     102733005   09159 Environmental adaptation    04713 Circadian entrainment     102733005    04714 Thermogenesis     102733005  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102733005    05207 Chemical carcinogenesis - receptor activation     102733005   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102733005    05163 Human cytomegalovirus infection     102733005   09165 Substance dependence    05032 Morphine addiction     102733005   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102733005   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102733005   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102733005 Enzymes [BR:lww01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102733005 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N Motif Other DBs NCBI-GeneID:  102733005 NCBI-ProteinID:  XP_030891638 UniProt:  A0A7F8RFX5 LinkDB All DBs Position Unknown AA seq 781 aa AA seqDB search MPERDSNSGLLIVISDLYVNVSLLKMAQYFSVSEKSGKPYERLVLSVLPRFVVLEMINDM TNVEDEHLQHQFHRIYIHRYENVRRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIE TYLIKQPEESLLSLPEDIVKESVSSSDGRNSGATFTEGSWSPELPFDNIVGKQNTLAALT RNSINLLPNHLAQALHVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHK ADIFPSKRVFGDLVKNTAPLGAVTKYYGLRAYKQLTQFSQFWRLEVQDQDTGTFSVWVMP MAIQFSILIMLHSALVLITTAEDYKCLPLVLRKTCCWINETYLARNVIIFASILINFLGA ILNIYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNLNHS GEDFLGTKEASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENM LRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRL LNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLAL TESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRI QVPEETYLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQY SLAAVVLGLVQSLNRQRQKQLLNENNNTGIIKGHYNRRTLLTPSGPEPGAQAEGTDKSDL P NT seq 2346 nt NT seq  +upstreamnt  +downstreamnt atgccagaaagagactcaaattcaggtcttctgattgtgatttccgacctatatgtcaat gtctctttgttgaaaatggcgcaatacttttctgtgtcggagaaaagtggcaaaccttac gagcggctcgtgctatctgtgctcccccgctttgtcgtcctggaaatgatcaacgacatg accaatgttgaagacgagcacttgcagcaccagttccatcggatctacatccaccgctat gagaacgtcaggaggattcacatttccaaagccacgctggactgcctcaacggtgactat aacgtagaagagggtcatggtaaagagagaaacgaattcttgaggaagcataatatagag acctatttgattaagcagcctgaggagagtctgctgtcattgcccgaagacattgtcaag gaatccgtgagctcctcagacgggagaaacagtggggcgacattcacagaaggatcctgg agccccgaactgccctttgataacatagtggggaaacagaacactctggctgccctaaca agaaattcaataaatctacttccaaaccatcttgcacaagctttgcatgtccagtctggg cctgaggaaattaacaagagaatagaacataccatcgacttgcggagtggcgataaattg agaagagagcatatcaagccattctcactgatgtttaaagactccagcctggagcacaag gctgatatttttccaagtaaaagagtatttggggatcttgttaaaaatacagctccttta ggagctgtcacaaaatactacggactgcgggcttataaacagctcacacagttctcacag ttctggaggctggaagtccaagatcaagacactggcacattcagtgtctgggtgatgcca atggccatccagttttccatcctgattatgctgcactcggctctggtcctcatcaccaca gcagaggattataagtgtttgcccctcgtcctccggaaaacttgctgttggattaacgag acctatttggcccggaacgtcatcatctttgcatccatcttgattaacttcctgggcgcc atcttgaatatctactttgtcttcaccggggtgctggccatggtgacctgtgcagttttc ctccgcctgaactctgtcttgaagctggcggtgctgctgattatgatcgccatctacgcc ctgctgaccgagaccatctatgcgggcctctttctgcgctatgacaacctgaaccacagt ggagaagatttcctggggacaaaggaggcatcactgctgctgatggccatgttcctcctt gctgtgttctaccatggacagcagctggagtacacagcccgccttgacttcctttggcga gtacaagccaaagaggagatcaatgagatgaaggagctgagggaacacaacgagaacatg ctccggaacattctacccagccacgtggcccgccacttcctggagaaagaccgagacaat gaggagctgtactctcaatcctatgatgccgtcggagtgatgttcgcctccatcccgggg tttgcagacttttactcgcagactgaaatgaataaccaaggagtggaatgcctgcgcctg ctgaatgagatcattgctgacttcgatgagctgcttggcgaagaccggttccaggacatt gaaaagattaagaccattggcagcacctacatggccgtgtcaggcctgtcccccgaaaaa cagcaatgtgaagacaagtggggacatttgtgcgccctggccgacttctccctcgccctg actgagagcatacaggagatcaacaagcattccttcaacaatttcgaactccggattggc atcagccacggctcggtggtagctggcgttatcggcgctaagaaaccacagtatgacatt tggggcaaaaccgtgaacctagcaagtcgaatggacagcacaggggtcagcggcaggatc caagtccctgaggagacctatctcatcctgaaggaccagggctttgcctttgactaccga ggggagatctatgtgaagggcatcagtgaacaggaaggaaaaatcaagacgtactttctg ctgggaagagtccaacccaacccattcatcctgcccccgagaagactgcccgggcagtac tccttggccgcggtcgtcctgggccttgtccagtccctcaacaggcaaaggcagaagcag ctcctcaacgagaacaacaacactgggattatcaagggtcattacaaccggcggactttg ttgacacccagcgggccagagcctggagcccaagctgaaggcaccgacaagtccgatttg ccataa

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