Leptonychotes weddellii (Weddell seal): 102737797 Help Entry 102737797         CDS       T08708                                  Symbol IRS4 Name (RefSeq) insulin receptor substrate 4   KO K17446   insulin receptor substrate 4 Organism lww  Leptonychotes weddellii (Weddell seal) Pathway lww04022   cGMP-PKG signaling pathway lww04068   FoxO signaling pathway lww04081   Hormone signaling lww04140   Autophagy - animal lww04152   AMPK signaling pathway lww04211   Longevity regulating pathway lww04213   Longevity regulating pathway - multiple species lww04910   Insulin signaling pathway lww04920   Adipocytokine signaling pathway lww04923   Regulation of lipolysis in adipocytes lww04930   Type II diabetes mellitus lww04935   Growth hormone synthesis, secretion and action lww05010   Alzheimer disease Brite KEGG Orthology (KO) [BR:lww00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     102737797 (IRS4)    04022 cGMP-PKG signaling pathway     102737797 (IRS4)    04152 AMPK signaling pathway     102737797 (IRS4)   09133 Signaling molecules and interaction    04081 Hormone signaling     102737797 (IRS4)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     102737797 (IRS4)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102737797 (IRS4)    04923 Regulation of lipolysis in adipocytes     102737797 (IRS4)    04920 Adipocytokine signaling pathway     102737797 (IRS4)    04935 Growth hormone synthesis, secretion and action     102737797 (IRS4)   09149 Aging    04211 Longevity regulating pathway     102737797 (IRS4)    04213 Longevity regulating pathway - multiple species     102737797 (IRS4)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     102737797 (IRS4)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102737797 (IRS4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS PH_11 PH_8 PH Motif Other DBs NCBI-GeneID:  102737797 NCBI-ProteinID:  XP_030888010 UniProt:  A0A7F8R3P0 LinkDB All DBs Position Unknown AA seq 1255 aa AA seqDB search MASGSFARDQATRRLRAAAAAAAAALAAAATTPLLSSGPPTALIGTGSSCPGAMWLSTAT GSRSDSESDEEDLPVGDEVCKRGYLRKQKHGHRRYFVLKLATADAPARLEYYENARKFRH SVRAAAAAAAAAASGAAVPALIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMV AENESEQESWYLLLSRLILESKRRRCGTPGASPDGEPAARGAAAAAEPPFYKDVWQVIVK PRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRST VIGPGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRTYSISVGAHLLTLLSTRRH LDTLPREPGGWLRRSRFEQFYHLRAIGDGEDEMLLTRRCLTPSEPVSPSRQGRLHLPRAR RSRRAISVPGSCFRRLPPSPVRVPPAAEVPSDRASGSGSSGEEGSPRGPEGQEGNGGDYM PMNRWGSGSGRGSGGGQGSSGQGSSSQGSGGNQCSGGGQGSGGGCQGSSGGQGSGGQGAG GNQRAGDGQGTAGGHGSGGGQGARGGGHGSGGGRGAGDGQGSGGGKNPGGGKGSGSGKTS EDNGERGKSLKKRSYFGKLTQSKQHMPPPPPPPPPPAGATGGKGKSGGRFRLYFCADRGA PKERKEAKEVKDLETPEGAARGPHRARAFDEDEDDPYVPMRPGVAAPLPSSGDYMPMAPQ NFSDSKRHSRSPFEDSRGYMMMFPRVSPPPAPSPPKEPDAEKEEESKDNDSESDYMFMAP GAGAIPKKPPNPQGGSSSKSWSSYLSLPNPFRGSPLGQSDHSEYVPMLPGKFPGKGLDKE ASSNRGPKDALSKPSVEGSFSKHGDGGSPSKPSDDGPPKNKAKRPNRLSFITKGNKIKPK SQKPTREQRGADSSRDYVNIDFTKRASNVPAPFIHGLPGSWGIIAGPRPTAFSNYVNVDF GPPFPNPAHRLSNLFRAIPGANPLFLEGARWPLAPLPPSATGGSANEEEGDYIEVIFNPA MTPAVPFGDSAIRYDAETGRIYVVDPFSECCMDISLTPSRCSEPPPVARLLQEEQQLERR RPQSHSQSFFGAARAAVSAFPTDSLERDLSASFASAAAASAAVPALALSRALAAASALAV APGIGAAARGLEAAARFDSASVRWFQPVAGAAAAAEAVRGPQNVAGGSSPRAPNPSADLA GGENGAAAAAPPPPPRRPVLSPPEREEPDDEDDDTYVRMDFARPDNKKFDPPRRE NT seq 3768 nt NT seq  +upstreamnt  +downstreamnt atggcgagtggctccttcgctcgcgaccaagcgacaaggagactgagagctgcagcggcg gcagcggcggcggctctagctgcggcggcgaccaccccacttctttcctcgggccccccg accgcactcattgggaccgggtcgtcttgtccgggagccatgtggctctccacggccact ggctcccggtcagactcggagtccgatgaggaggacctccccgtcggggacgaagtctgc aaacgcggctacctgcggaagcagaagcacgggcaccggcgctacttcgtgctcaaactc gcgaccgccgacgccccggctcggctagaatactacgaaaacgccaggaagttccggcac agtgtccgcgccgcggcggcggcggcggcggcggcggcgtccggcgccgcggtccccgcg ctcatcccgccgcggcgcgtgatcaccctgtaccagtgcttctccgtgagccagcgagcc gacgcgaggtaccgacacctcatcgccctcttcacccaggacgagtacttcgccatggtg gccgagaacgagtcggagcaggagagctggtacttgctgctcagccgcctcatcctcgag agcaagcgccgccgctgcggcacgcccggcgcgtcgccggatggggagccggccgcgcgg ggggctgcagcggcggcggagccacccttctacaaggatgtgtggcaggtaatagtcaaa cccagggggctggggcacagaaaagagctgagcggcgtgttccggctctgtcttaccgac gaggaggtggtgtttgtgaggctgaataccgaggtggccagcgtggtcgtccagctcctg agcatccgtcgctgcgggcactcggagcagtatttcttcttggaagtcggtaggtccacc gtcatcggtcccggcgagctgtggatgcaggtcgatgactgtgtggtggcccaaaacatg cacgagctctttttggagaagatgagagccctgtgtgcagacgaataccgagcccgctgc cgcacctacagcatcagcgtcggcgcccacctgttaaccctgctgtccactaggaggcac ctggacacgctgccgcgcgagcccggcggctggctgagaaggtcccgctttgagcagttt taccacctcagggccatcggtgacggggaagacgagatgctcctcaccaggcgctgccta acacccagcgaacccgtgtccccctccaggcaaggaagactgcacctgccccgagcgcgc aggtcccggagagcgatttcagtgcccggcagctgttttcgccgcctcccccccagcccg gtgcgtgtcccgcctgccgcagaagtcccgagcgacagagcttctggctccggcagctct ggggaagaaggcagccctcggggcccagagggtcaggaaggaaacggaggtgactacatg cccatgaacagatggggctcgggaagtggccggggttccggaggtggccagggctccagt ggccaaggctccagtagccagggttcgggaggaaaccagtgctcgggcggggggcagggc tccggaggaggctgccagggctccagcggtggccagggctcggggggccagggggcagga ggaaaccagcgtgcaggcgatggccagggcactgcaggtgggcatggctcgggcggtggc cagggagcccgcggcggcggacacggctcaggcggtgggcggggagccggagatggccag ggctcaggcgggggcaagaaccccggagggggcaaaggctcaggaagtgggaaaacctcc gaggacaatggtgagcgcggaaaatctctgaagaaaaggtcctactttggcaaattaact caaagcaagcagcacatgccgcctcctccgccgcctccgcccccaccggctggagcaact ggtggtaaagggaagtccgggggaaggttccggctctatttttgtgccgacagaggagcc ccaaaagaacgcaaagaggccaaggaggtcaaagacttagagaccccagaaggtgcagcg cggggtccccacagagccagagcttttgacgaagatgaggatgacccatacgtgccaatg aggccaggggtggcggcccctctcccaagctccggtgattacatgccaatggctccccaa aacttctctgattcaaaacgccactctcggtcaccttttgaagattcaagagggtacatg atgatgtttcccagagtgagcccaccacctgccccaagtccccccaaagagccggatgct gaaaaggaggaggagtcaaaggacaatgacagtgagagtgactatatgtttatggctcct ggagccggtgcaattccaaaaaaacccccaaatcctcagggtggctcttcctctaaaagt tggagctcctacctatccctgccgaatccttttcggggctccccgttgggacagagtgac cacagtgagtatgtaccaatgttacctggaaaattccccgggaagggcctagacaaggaa gcctcatcgaaccggggccccaaagatgccctttcaaagccttcagttgaggggtcattc tcgaagcatggagatggggggtcaccctcaaagccttcagatgatgggccccccaagaac aaggctaagagacctaaccgcctctcttttatcacaaaaggaaataaaatcaagccaaaa tcacaaaagcccacacgtgaacagagaggagctgacagctctcgtgactacgtcaacatt gacttcactaagagagcgagcaatgtaccagccccctttatccacggactgccaggctcg tggggcatcattgctggccccagaccgacagccttttctaactatgtgaatgtggacttc ggaccgccatttccaaacccagcacacaggctctcgaatcttttcagagccattccaggt gccaaccccctctttctggaaggtgctaggtggccccttgcgcctcttcctcccagcgct acaggtggcagtgcgaatgaggaagagggcgactacattgaagtgattttcaatccagca atgacgccggccgtgccttttggtgacagtgccattcgctatgatgctgaaacaggtcgc atctatgtggtcgacccgttttctgagtgctgtatggacatttctctcacccccagccgc tgttccgagccaccgcctgtagctaggctgctgcaggaagaacagcagctggagcgaaga cgcccgcaaagccattcgcaaagtttctttggggccgccagggccgcggtctcggctttc ccaacggacagcctcgagagagacctctcggcctcctttgcctcggccgccgccgcttcg gcagctgtgccggccttagccttgagccgggcgttagccgccgcctcggccctggccgtg gccccgggcatcggggcagccgcgcggggcttggaggccgccgctcggtttgactccgcc tccgtccgctggttccaacctgttgctggcgccgctgcggccgccgaagcggtcaggggg ccccaaaacgttgccggtggctcgagcccgagagctcccaacccgtcggcagacctagcc ggaggtgagaacggggccgccgcggccgccccgcccccaccgcctcgccgcccggtgctg agtccccccgagcgagaggagcctgacgacgaagacgacgacacctacgtgagaatggac tttgccagacctgacaacaagaagttcgaccctccccgcagagagtga

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