Leptonychotes weddellii (Weddell seal): 102741876 Help Entry 102741876         CDS       T08708                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism lww  Leptonychotes weddellii (Weddell seal) Pathway lww04022   cGMP-PKG signaling pathway lww04068   FoxO signaling pathway lww04081   Hormone signaling lww04140   Autophagy - animal lww04152   AMPK signaling pathway lww04211   Longevity regulating pathway lww04213   Longevity regulating pathway - multiple species lww04910   Insulin signaling pathway lww04920   Adipocytokine signaling pathway lww04923   Regulation of lipolysis in adipocytes lww04930   Type II diabetes mellitus lww04931   Insulin resistance lww04932   Non-alcoholic fatty liver disease lww04935   Growth hormone synthesis, secretion and action lww05010   Alzheimer disease lww05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:lww00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     102741876 (IRS2)    04022 cGMP-PKG signaling pathway     102741876 (IRS2)    04152 AMPK signaling pathway     102741876 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     102741876 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     102741876 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102741876 (IRS2)    04923 Regulation of lipolysis in adipocytes     102741876 (IRS2)    04920 Adipocytokine signaling pathway     102741876 (IRS2)    04935 Growth hormone synthesis, secretion and action     102741876 (IRS2)   09149 Aging    04211 Longevity regulating pathway     102741876 (IRS2)    04213 Longevity regulating pathway - multiple species     102741876 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     102741876 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     102741876 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102741876 (IRS2)    04932 Non-alcoholic fatty liver disease     102741876 (IRS2)    04931 Insulin resistance     102741876 (IRS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N Mcp5_PH Motif Other DBs NCBI-GeneID:  102741876 NCBI-ProteinID:  XP_030883209 UniProt:  A0A7F8QPV1 LinkDB All DBs Position Unknown AA seq 999 aa AA seqDB search PNLNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGDEATATAGGGPAPQPPRLEYYESE KKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDEYFAVAAENEQEQEGWYRAL TDLVSEGRAGDAPPAAATAASCSASLPGALGGSAGAAAADDSYGLVAPATAAYREVWQVN LKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLMNIRRCGHSDSFFFIEVGR SAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRPRSKSQSSGSSSTHPISVPG ARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRVRTXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXPLSRSHTLSGGCGARASKVALAPAGGALQHSRSMSMPVAHSPPA ATSPSSLSSSSGHGSGSYPPPPGPHPHLQHPLHQPASQRPSSGSASASGSPSDPGFMSLD EYGSSPGDLRAFCSHRSNTPESIAETPPARDGSGGELYGYMTMDRPLSHCGRPYRRVSGD GAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSGSSGRLCPSCPVSSPK VAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGVALLGGGSGSCKSDDYMPMSPTS VSAPKQILQPRAAAAAPPPTGAAVPAPTPTVSRAFPANGGGYKTSSPGESSPEDSGYMRM WCGSKLSVENADAKLLPNGDYLNMSPSDAGTSGTPPDFFSAALHGSGEMLRGVPGYCYSS LPRSYKAPYTCNGDNDQYVLMSSPVGRILEEERLEPPAGPGTAPSTCALAAAGGHTQPPH PVVPSPSRPSGSLGGRPDGFLNQRCRLVRPTRLSLEGLQTLPSMHEYPLPPEPKSPGEYI NIDFGEAAARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMN LDFSSPKSPKPGPQSGDPVGSLDALLSPEASSPYPPLPP NT seq 2997 nt NT seq  +upstreamnt  +downstreamnt cccaacctcaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgc aagcagaagcacggccacaagcgcttcttcgtgctgcgcgggcccggcgacgaggcgacg gcgacagcgggcggggggccggcgccgcagccgccgcggctcgagtactacgagagcgag aagaagtggcggagcaaggcgggcgccccgaagcgggtcatcgcgctcgactgctgcctg aacatcaacaagcgcgccgacgccaagcacaagtacctgatcgcgctgtacaccaaggac gagtacttcgcggtggcggccgagaacgagcaggagcaggagggctggtaccgcgcgctc accgacctggtcagcgagggccgcgccggcgacgcgccccccgccgccgccaccgccgcg tcctgcagcgcctccctgcccggcgccctgggcggctcggccggcgccgccgcggccgat gacagctacgggctggtggcgcccgccacggccgcctaccgcgaggtgtggcaggtgaac ctgaagcccaagggcctgggccagagcaagaacctgacgggcgtgtaccgcctgtgcctg tcggcgcgcaccatcggcttcgtgaagctcaactgtgagcagccgtcggtgacgctgcag ctcatgaacatccgccgctgcggccactcggacagcttcttcttcattgaggtgggccgg tcggccgtcacgggcccaggtgagctgtggatgcaggccgacgactcggtggtggcgcag aacatccacgagaccatcctggaggccatgaaggctctcaaggagctcttcgagttccgg ccgcgcagtaagagccagtcgtcgggctcgtcctccacacaccccatcagcgtccctggc gcgcgccgccaccaccacctggtcaacctgccccccagccagacgggcctggtgcgccgc tcgcgcaccgacagcctggccgccactccgccggccgcgaagtgcagctcctgtcgggtg cgcacnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnngcccctgagccgc tcacacaccctgagcggcggctgcggcgcccgcgcgagcaaggtggcgctggcgccggca gggggcgccctgcaacacagccgctccatgtccatgccggtggcgcactcgcccccagcc gccaccagccccagcagcctgtcgtccagcagcgggcacggctccggctcctacccgccg cctccaggcccgcacccgcacctgcagcaccccctgcaccagcccgcgagccagcggccc tccagcggcagcgcctcggcctcgggctcccccagcgatcctggcttcatgtccctggat gagtacggctccagccctggggacctgagagccttctgcagccaccggagcaacacgccc gagtccatcgctgagacacccccggccagggacggcagcgggggcgagctgtacgggtac atgactatggacaggcccctgagccactgtggccgcccctaccgcagggtctcgggggat ggggcccaggacttggaccgagggctgaggaagaggacttactccctgaccacacctgcc cggcagcggccggtgccccagccctcctctgcgtccctggatgaatacaccctgatgcgg gccaccttctctggcagctccggccgcctctgcccgtcttgtcccgtgtcgtctcccaaa gtggcctaccacccctaccccgaggactacggcgacatcgagatcgggtcccataggagc tctagcagtaacctgggtgccgacgatggctacatgcccatgacccctggcgtggccctc ctgggtggtggcagcggcagctgtaagagtgatgactacatgcccatgagccccactagc gtgtctgccccgaagcagatcctgcagcctcgcgccgccgccgcagccccgccccccacg ggagccgcagtgccggcgcccacccctacggtcagcagggcgtttccagccaacgggggc ggctacaagacgagctccccaggcgagagctcccctgaggacagtgggtacatgcgcatg tggtgtggctccaagctgtccgtggagaatgccgacgccaagctgctacccaacggggac tacctcaacatgtcccccagcgacgcgggtacctcggggacccctcccgacttcttctca gcagccttgcatggcagcggggagatgctcaggggagtccccggctattgctatagctcc ctgccccgctcctacaaggctccctacacgtgcaacggggacaacgaccagtacgtgctc atgagctcccccgtggggcgcatcctggaagaagagaggctggaaccgccggccggcccg gggaccgcgccgtccacgtgcgctctcgcggcggcgggcggccacacccagcctcctcac ccagtagtgccttcgcccagcaggccgagtggcagccttggtggccgccccgacggcttc ctgaaccagcgctgccggttagtgcggcccacacgcctgtccctggaggggcttcagacc ctgcccagcatgcacgagtacccgctgccgcccgagcccaagagccccggcgagtacatc aacattgacttcggcgaggccgcggctcgcctgtctccgcccgcgcctccgctgctggct tcggcggcctcctcgtcctcgctgctgtcggccagcagcccggcctcatccctaggctcg ggcaccccgggcacgagcagcgacagcaggcagcgctccccactctccgactacatgaac ctcgacttcagctcgcccaagtcacccaagccgggcccccagagcggggaccccgtgggc tccctggatgccctcctgtcccccgaggcctcgtccccctacccgccgctgcccccg

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