Leptonychotes weddellii (Weddell seal): 102743506 Help Entry 102743506         CDS       T08708                                  Symbol TNF Name (RefSeq) tumor necrosis factor   KO K03156   tumor necrosis factor superfamily, member 2 Organism lww  Leptonychotes weddellii (Weddell seal) Pathway lww01523   Antifolate resistance lww04010   MAPK signaling pathway lww04060   Cytokine-cytokine receptor interaction lww04061   Viral protein interaction with cytokine and cytokine receptor lww04064   NF-kappa B signaling pathway lww04071   Sphingolipid signaling pathway lww04150   mTOR signaling pathway lww04210   Apoptosis lww04217   Necroptosis lww04350   TGF-beta signaling pathway lww04380   Osteoclast differentiation lww04612   Antigen processing and presentation lww04620   Toll-like receptor signaling pathway lww04621   NOD-like receptor signaling pathway lww04622   RIG-I-like receptor signaling pathway lww04625   C-type lectin receptor signaling pathway lww04640   Hematopoietic cell lineage lww04650   Natural killer cell mediated cytotoxicity lww04657   IL-17 signaling pathway lww04660   T cell receptor signaling pathway lww04664   Fc epsilon RI signaling pathway lww04668   TNF signaling pathway lww04920   Adipocytokine signaling pathway lww04930   Type II diabetes mellitus lww04931   Insulin resistance lww04932   Non-alcoholic fatty liver disease lww04933   AGE-RAGE signaling pathway in diabetic complications lww04936   Alcoholic liver disease lww04940   Type I diabetes mellitus lww05010   Alzheimer disease lww05014   Amyotrophic lateral sclerosis lww05020   Prion disease lww05022   Pathways of neurodegeneration - multiple diseases lww05132   Salmonella infection lww05133   Pertussis lww05134   Legionellosis lww05135   Yersinia infection lww05140   Leishmaniasis lww05142   Chagas disease lww05143   African trypanosomiasis lww05144   Malaria lww05145   Toxoplasmosis lww05146   Amoebiasis lww05152   Tuberculosis lww05160   Hepatitis C lww05161   Hepatitis B lww05163   Human cytomegalovirus infection lww05164   Influenza A lww05165   Human papillomavirus infection lww05166   Human T-cell leukemia virus 1 infection lww05168   Herpes simplex virus 1 infection lww05169   Epstein-Barr virus infection lww05170   Human immunodeficiency virus 1 infection lww05171   Coronavirus disease - COVID-19 lww05205   Proteoglycans in cancer lww05310   Asthma lww05321   Inflammatory bowel disease lww05322   Systemic lupus erythematosus lww05323   Rheumatoid arthritis lww05330   Allograft rejection lww05332   Graft-versus-host disease lww05410   Hypertrophic cardiomyopathy lww05414   Dilated cardiomyopathy lww05417   Lipid and atherosclerosis lww05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:lww00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     102743506 (TNF)    04350 TGF-beta signaling pathway     102743506 (TNF)    04064 NF-kappa B signaling pathway     102743506 (TNF)    04668 TNF signaling pathway     102743506 (TNF)    04071 Sphingolipid signaling pathway     102743506 (TNF)    04150 mTOR signaling pathway     102743506 (TNF)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     102743506 (TNF)    04061 Viral protein interaction with cytokine and cytokine receptor     102743506 (TNF)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     102743506 (TNF)    04217 Necroptosis     102743506 (TNF)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     102743506 (TNF)    04620 Toll-like receptor signaling pathway     102743506 (TNF)    04621 NOD-like receptor signaling pathway     102743506 (TNF)    04622 RIG-I-like receptor signaling pathway     102743506 (TNF)    04625 C-type lectin receptor signaling pathway     102743506 (TNF)    04650 Natural killer cell mediated cytotoxicity     102743506 (TNF)    04612 Antigen processing and presentation     102743506 (TNF)    04660 T cell receptor signaling pathway     102743506 (TNF)    04657 IL-17 signaling pathway     102743506 (TNF)    04664 Fc epsilon RI signaling pathway     102743506 (TNF)   09152 Endocrine system    04920 Adipocytokine signaling pathway     102743506 (TNF)   09158 Development and regeneration    04380 Osteoclast differentiation     102743506 (TNF)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     102743506 (TNF)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102743506 (TNF)    05170 Human immunodeficiency virus 1 infection     102743506 (TNF)    05161 Hepatitis B     102743506 (TNF)    05160 Hepatitis C     102743506 (TNF)    05171 Coronavirus disease - COVID-19     102743506 (TNF)    05164 Influenza A     102743506 (TNF)    05168 Herpes simplex virus 1 infection     102743506 (TNF)    05163 Human cytomegalovirus infection     102743506 (TNF)    05169 Epstein-Barr virus infection     102743506 (TNF)    05165 Human papillomavirus infection     102743506 (TNF)   09171 Infectious disease: bacterial    05132 Salmonella infection     102743506 (TNF)    05135 Yersinia infection     102743506 (TNF)    05133 Pertussis     102743506 (TNF)    05134 Legionellosis     102743506 (TNF)    05152 Tuberculosis     102743506 (TNF)   09174 Infectious disease: parasitic    05146 Amoebiasis     102743506 (TNF)    05144 Malaria     102743506 (TNF)    05145 Toxoplasmosis     102743506 (TNF)    05140 Leishmaniasis     102743506 (TNF)    05142 Chagas disease     102743506 (TNF)    05143 African trypanosomiasis     102743506 (TNF)   09163 Immune disease    05310 Asthma     102743506 (TNF)    05322 Systemic lupus erythematosus     102743506 (TNF)    05323 Rheumatoid arthritis     102743506 (TNF)    05321 Inflammatory bowel disease     102743506 (TNF)    05330 Allograft rejection     102743506 (TNF)    05332 Graft-versus-host disease     102743506 (TNF)   09164 Neurodegenerative disease    05010 Alzheimer disease     102743506 (TNF)    05014 Amyotrophic lateral sclerosis     102743506 (TNF)    05020 Prion disease     102743506 (TNF)    05022 Pathways of neurodegeneration - multiple diseases     102743506 (TNF)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102743506 (TNF)    05418 Fluid shear stress and atherosclerosis     102743506 (TNF)    05410 Hypertrophic cardiomyopathy     102743506 (TNF)    05414 Dilated cardiomyopathy     102743506 (TNF)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102743506 (TNF)    04940 Type I diabetes mellitus     102743506 (TNF)    04936 Alcoholic liver disease     102743506 (TNF)    04932 Non-alcoholic fatty liver disease     102743506 (TNF)    04931 Insulin resistance     102743506 (TNF)    04933 AGE-RAGE signaling pathway in diabetic complications     102743506 (TNF)   09176 Drug resistance: antineoplastic    01523 Antifolate resistance     102743506 (TNF)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:lww04052]     102743506 (TNF)    00536 Glycosaminoglycan binding proteins [BR:lww00536]     102743506 (TNF) Cytokines and neuropeptides [BR:lww04052]  Cytokines   Tumor necrosis fators    102743506 (TNF) Glycosaminoglycan binding proteins [BR:lww00536]  Heparan sulfate / Heparin   Cytokines    102743506 (TNF) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TNF ANAPC16 Motif Other DBs NCBI-GeneID:  102743506 NCBI-ProteinID:  XP_006738541 UniProt:  A0A2U3Y499 LinkDB All DBs Position Unknown AA seq 233 aa AA seqDB search MSTESMIRDVELAEEALPKKAGGPQGSRRFLCLSLFSFLLVAGATTLFCLLHFGVIGPQR EELPDGLQLINPLAQTVKSSSRTPSDKPVAHVVANPEAEGQLQWLSRRANALLANGVELT DNQLIVPSDGLYLIYSQVLFKGQGCPSTHVLLTHTISRFAVSYQTKVNLLSAIKSPCQRE TPEGTEAKPWYEPIYLGGVFQLEKGDRLSAEINLPDYLDFAESGQVYFGIIAL NT seq 702 nt NT seq  +upstreamnt  +downstreamnt atgagcactgaaagcatgatccgggacgtggagctggccgaggaggcactccctaagaag gcagggggcccccagggctccagaaggttcttgtgcctcagcctcttctccttcctcctc gttgcaggagccaccacgctcttctgcctgttgcacttcggagtgatcggcccccagagg gaagagctcccagatggcctccaactaatcaaccctctggcccagacagtcaaatcatct tctcgaactccaagtgacaagcctgtagctcatgttgtagcaaaccccgaagctgagggg caactccagtggctgagccggcgtgccaatgccctcctggccaatggtgtggagctgaca gataaccagctaatagtgccatcagacgggctgtacctcatctactcccaggtcctcttc aagggccaaggatgcccttccacccatgtgctcctcacccacaccatcagccgcttcgcc gtctcctaccagaccaaggtcaacctcctctctgccatcaagagcccttgccaaagggag accccagaggggactgaggccaagccctggtacgagcccatctacctgggaggggtcttc caactggagaagggtgatcgactcagcgctgagatcaacctgcctgactatctcgacttt gccgagtctgggcaggtctactttggaatcattgccctgtga

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