Leptonychotes weddellii (Weddell seal): 102750079
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Entry
102750079 CDS
T08708
Symbol
ALOX12
Name
(RefSeq) arachidonate 12-lipoxygenase, 12S-type isoform X1
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
lww
Leptonychotes weddellii (Weddell seal)
Pathway
lww00590
Arachidonic acid metabolism
lww01100
Metabolic pathways
lww01523
Antifolate resistance
lww04726
Serotonergic synapse
lww04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
lww00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
102750079 (ALOX12)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
102750079 (ALOX12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
102750079 (ALOX12)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102750079 (ALOX12)
Enzymes [BR:
lww01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
102750079 (ALOX12)
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Ortholog
Paralog
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Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
102750079
NCBI-ProteinID:
XP_006743183
UniProt:
A0A2U3YHW8
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All DBs
Position
Unknown
AA seq
663 aa
AA seq
DB search
MGRYRIRVATGAWLFSGSHNSVQLWLVGACGEAELQLQLRPARGQEEEFDRDVPKDLGPL
QFVKLRKHHSLVDDAWFCDLITVRGPGACEEAAFPCYRWVQGQGVLSLPEGTARLAGDNA
LDVFQKHREKELKERQELYCWDTWKEGLPLTIAAGCQDDLPPNMRFHEDKRLDFEWALKA
GALEMVLKRVYTLLSSWNRPEDFDQIFWGQKSALAEKVHQCWRDDELFGYQFLNGANPML
LRRSTSLPCRLVLPPGLEALGAQLERELQNGSLFEADFILLDGIPANVIRGEKQYLAAPL
VLLRMTPNGKLLPVVIQIQPPSPSTPTPQLFLPSDPPFAWLLAKAWVRNADFQLHQLQYH
LLNTHLVAEVIAVATMRRLPGLHPVFKLLIPHIRYTMEINTRARSQLISEGGIFDKAVST
GGGGHVQLLRRAMAQLTYRSLCPPDDLADRGLLGIPSALYAHDALRLWGITARYVEGIVH
LFYHRDDIVRGDPELQAWCREITEVGLCQAQDRGFPVSFQSRKQLCHFLTMCVFTCTAQH
GAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMTTVMGSLPDVRQACLQMTITWHLGRR
QPDMVPLGHHKEKYFSSPKAKAVLNQFQTDLESLEREITARNEQLDLPYDYLKPSRIENS
VTI
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atgggccgctaccgcatccgcgtggccaccggggcctggctcttctcggggtcgcacaac
agcgtgcagctgtggctggtcggggcgtgcggggaggcggagctgcagctgcagctgcgg
ccggcgcggggccaggaggaggaatttgatcgcgacgttcccaaggacttggggcccctg
cagttcgtgaagctgcgcaaacaccactccctggtggacgacgcgtggttctgcgacctc
atcacagtgcggggcccgggtgcctgcgaggaggccgccttcccctgctaccgctgggtg
cagggccagggcgtgctgagcctgcccgagggcaccgcacgccttgcaggagacaatgcc
ctggacgtgttccagaagcatcgagagaaagaactgaaggaaagacaagagctgtactgc
tgggacacctggaaggaggggttacccctgaccatagctgccgggtgtcaggacgatctg
cctccaaacatgagattccatgaggacaagaggctggacttcgagtgggcactgaaggcg
ggggcgctagagatggtcctcaaacgtgtttacaccctcctgagctcctggaatcgcccg
gaggattttgatcagatcttctggggccagaagagcgccctggctgagaaggtccaccag
tgctggcgggacgatgagctttttggctaccagttcctcaatggcgccaaccccatgctg
ttgagacgctccacctctctgccctgccggctcgtgctgccccccgggctggaggcactg
ggggcccagctggagagagagctccagaacggttccctgtttgaggccgacttcatcctg
ctggatggaattccagccaacgtgatccggggcgagaagcagtacctggccgcccccctt
gtcctgctgcggatgacacccaatgggaagctcctgcccgtggtcatccagatccagcct
cccagccccagcacccccaccccccagctgttcctgccctcagatcccccattcgcctgg
ctcctggcaaaggcctgggtccgaaatgccgactttcaactgcaccagctccagtatcat
ctgctgaacactcacctggtggccgaggtcattgctgtggccaccatgaggcgcctcccg
gggctgcacccggtcttcaagctcctgatcccgcacatccgctacaccatggagatcaac
acccgggccagatcccagctcatctcagaaggaggaatatttgataaggcggtgagcacc
ggcggagggggccacgtgcagttgctgcgtcgggccatggctcagctgacctaccgctcc
ctctgtcctcctgatgacctggctgaccgtggcctgctgggaatcccaagtgccctctac
gcgcatgatgctttacggctctgggggatcactgcccggtacgtggagggcatcgtccac
ctcttctaccacagggatgacatcgtgagaggggacccggagctgcaggcctggtgtcgg
gagatcactgaggtggggctgtgccaggcccaggaccgaggtttccccgtctccttccag
tcccggaagcaactctgccatttccttaccatgtgtgtcttcacatgcactgctcagcac
ggggccatcaaccagggccagctggactggtatgcctgggtccctaatgccccatgcaca
atgcggatgcccccacccaccaccaaggaagatgtaacaatgaccacggtgatgggctca
ctacctgatgtccgacaggcctgtcttcaaatgaccatcacatggcatctggggcgccgc
cagccagacatggtgcctctggggcatcacaaagaaaaatatttctcaagccccaaggcc
aaggctgtattaaaccaattccaaacggatttggaaagcctggaaagagagattacagcc
cggaatgagcaactcgacctgccctatgactacctgaagcccagccgcatagagaacagt
gtcaccatctga
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