Mycobacterium tuberculosis variant africanum: MAF_12670
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Entry
MAF_12670 CDS
T01575
Symbol
sucA
Name
(GenBank) putative 2-oxoglutarate dehydrogenase SUCA (alpha-ketoglutarate dehydrogenase)
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
maf
Mycobacterium tuberculosis variant africanum
Pathway
maf00020
Citrate cycle (TCA cycle)
maf00630
Glyoxylate and dicarboxylate metabolism
maf00785
Lipoic acid metabolism
maf01100
Metabolic pathways
maf01110
Biosynthesis of secondary metabolites
maf01120
Microbial metabolism in diverse environments
maf01200
Carbon metabolism
maf01210
2-Oxocarboxylic acid metabolism
Module
maf_M00009
Citrate cycle (TCA cycle, Krebs cycle)
maf_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
maf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
MAF_12670 (sucA)
00630 Glyoxylate and dicarboxylate metabolism
MAF_12670 (sucA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MAF_12670 (sucA)
Enzymes [BR:
maf01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
MAF_12670 (sucA)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
MAF_12670 (sucA)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
MAF_12670 (sucA)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
MAF_12670 (sucA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
CCC26339
LinkDB
All DBs
Position
complement(1388094..1391738)
Genome browser
AA seq
1214 aa
AA seq
DB search
MYRKFRDDPSSVDPSWHEFLVDYSPEPTSQPAAEPTRVTSPLVAERAAAAAPQAPPKPAD
TAAAGNGVVAALAAKTAVPPPAEGDEVAVLRGAAAAVVKNMSASLEVPTATSVRAVPAKL
LIDNRIVINNQLKRTRGGKISFTHLLGYALVQAVKKFPNMNRHYTEVDGKPTAVTPAHTN
LGLAIDLQGKDGKRSLVVAGIKRCETMRFAQFVTAYEDIVRRARDGKLTTEDFAGVTISL
TNPGTIGTVHSVPRLMPGQGAIIGVGAMEYPAEFQGASEERIAELGIGKLITLTSTYDHR
IIQGAESGDFLRTIHELLLSDGFWDEVFRELSIPYLPVRWSTDNPDSIVDKNARVMNLIA
AYRNRGHLMADTDPLRLDKARFRSHPDLEVLTHGLTLWDLDRVFKVDGFAGAQYKKLRDV
LGLLHDAYCRHIGVEYAHILDPEQKEWLEQRVETKHVKPTVAQQKYILSKLNAAEAFETF
LQTKYVGQKRFSLEGAESVIPMMDAAIDQCAEHGLDEVVIGMPHRGRLNVLANIVGKPYS
QIFTEFEGNLNPSQAHGSGDVKYHLGATGLYLQMFGDNDIQVSLTANPSHLEAVDPVLEG
LVRAKQDLLDHGSIDSDGQRAFSVVPLMLHGDAAFAGQGVVAETLNLANLPGYRVGGTIH
IIVNNQIGFTTAPEYSRSSEYCTDVAKMIGAPIFHVNGDDPEACVWVARLAVDFRQRFKK
DVVIDMLCYRRRGHNEGDDPSMTNPYMYDVVDTKRGARKSYTEALIGRGDISMKEAEDAL
RDYQGQLERVFNEVRELEKHGVQPSESVESDQMIPAGLATAVDKSLLARIGDAFLALPNG
FTAHPRVQPVLEKRREMAYEGKIDWAFGELLALGSLVAEGKLVRLSGQDSRRGTFSQRHS
VLIDRHTGEEFTPLQLLATNSDGSPTGGKFLVYDSPLSEYAAVGFEYGYTVGNPDAVVLW
EAQFGDFVNGAQSIIDEFISSGEAKWGQLSNVVLLLPHGHEGQGPDHTSARIERFLQLWA
EGSMTIAMPSTPSNYFHLLRRHALDGIQRPLIVFTPKSMLRHKAAVSEIKDFTEIKFRSV
LEEPTYEDGIGDRNKVSRILLTSGKLYYELAARKAKDNRNDLAIVRLEQLAPLPRRRLRE
TLDRYENVKEFFWVQEEPANQGAWPRFGLELPELLPDKLAGIKRISRRAMSAPSSGSSKV
HAVEQQEILDEAFG
NT seq
3645 nt
NT seq
+upstream
nt +downstream
nt
atgtaccgcaagttccgcgacgacccctcctcggtcgatcccagctggcacgagttcctg
gttgactacagccccgaacccacctcccaaccagctgccgaaccaacccgggttacctcg
ccactcgttgccgagcgggccgctgcggccgccccgcaggcaccccccaagccggccgac
accgcggccgcgggcaacggcgtggtcgccgcactggccgccaaaactgccgttcccccg
ccagccgaaggtgacgaggtagcggtgctgcgcggcgccgccgcggccgtcgtcaagaac
atgtccgcgtcgttggaggtgccgacggcgaccagcgtccgggcggtcccggccaagcta
ctgatcgacaaccggatcgtcatcaacaaccagttgaagcggacccgcggcggcaagatc
tcgttcacgcatttgctgggctacgccctggtgcaggcggtgaagaaattcccgaacatg
aaccggcactacaccgaagtcgacggcaagcccaccgcggtcacgccggcgcacaccaat
ctcggcctggcgatcgacctgcaaggcaaggacgggaagcgttccctggtggtggccggc
atcaagcggtgcgagaccatgcgattcgcgcagttcgtcacggcctacgaagacatcgta
cgccgggcccgcgacggcaagctgaccactgaagactttgccggcgtgacgatttcgctg
accaatcccggaaccatcggcaccgtgcattcggtgccgcggctgatgcccggccagggc
gccatcatcggcgtgggcgccatggaataccccgccgagtttcaaggcgccagcgaggaa
cgcatcgccgagctgggcatcggcaaattgatcactttgacctccacctacgaccaccgc
atcatccagggcgcggaatcgggcgacttcctgcgcaccatccacgagttgctgctctcg
gatggcttctgggacgaggtcttccgcgaactgagcatcccatatctgccggtgcgctgg
agcaccgacaaccccgactcgatcgtcgacaagaacgctcgcgtcatgaacttgatcgcg
gcctaccgcaaccgcggccatctgatggccgataccgacccgctgcggttggacaaagct
cggttccgcagtcaccccgacctcgaagtgctgacccacggcctgacgctgtgggatctc
gatcgggtgttcaaggtcgacggctttgccggtgcgcagtacaagaaactgcgcgacgtg
ctgggcttgctgcacgatgcctactgccgccacatcggcgtggagtacgcccatatcctc
gaccccgaacaaaaggagtggctcgaacaacgggtcgagaccaagcacgtcaaacccact
gtggcccaacagaaatacatcctcagcaagctcaacgccgccgaggcctttgaaacgttc
ctacagaccaagtacgtcggccagaagcggttctcgctggaaggcgccgaaagcgtgatc
ccgatgatggacgcggcgatcgaccagtgcgctgagcacggcctcgacgaggtggtcatc
gggatgccgcaccggggccggctcaacgtgctggccaacatcgtcggcaagccgtactcg
cagatcttcaccgagttcgagggcaacctgaatccgtcgcaggcgcacggctccggtgac
gtcaagtaccacctgggcgccaccgggctgtacctgcagatgttcggcgacaacgacatt
caggtgtcgctgaccgccaacccgtcgcatctggaggccgtcgacccggtgctggaggga
ttggtgcgggccaagcaggatctgctcgaccacggaagcatcgacagcgacggccaacgg
gcgttctcggtggtgccgctgatgttgcatggcgatgccgcgttcgccggtcagggtgtg
gtcgccgagacgctgaacctggcgaatctgccgggctaccgcgtcggcggcaccatccac
atcatcgtcaacaaccagatcggcttcaccaccgcgcccgagtattccaggtccagcgag
tactgcaccgacgtcgcaaagatgatcggggcaccgatctttcacgtcaacggcgacgac
ccggaggcgtgtgtctgggtggcgcggttggcggtggacttccgacaacggttcaagaag
gacgtcgtcatcgacatgctgtgctaccgccgccgcgggcacaacgagggtgacgacccg
tcgatgaccaacccctacatgtacgacgtcgtcgacaccaagcgcggggcccgcaaaagc
tacaccgaagccctgatcggacgtggcgacatctcgatgaaggaggccgaggacgcgctg
cgcgactaccagggccagctggaacgggtgttcaacgaagtgcgcgagctggagaagcac
ggtgtgcagccgagcgagtcggtcgagtccgaccagatgattcccgcggggctggccact
gcggtggacaagtcgctgctggcccggatcggcgatgcgttcctcgccttgccgaacggc
ttcaccgcgcacccgcgagtccaaccggtgctggagaagcgccgggagatggcctatgaa
ggcaagatcgactgggcctttggcgagctgctggcgctgggctcgctggtggccgaaggc
aagctggtgcgcttgtcggggcaggacagccgccgcggcaccttctcccagcggcattcg
gttctcatcgaccgccacactggcgaggagttcacaccactgcagctgctggcgaccaac
tccgacggcagcccgaccggcggaaagttcctggtctacgactcgccactgtcggagtac
gccgccgtcggcttcgagtacggctacactgtgggcaatccggacgccgtggtgctctgg
gaggcgcagttcggcgacttcgtcaacggcgcacagtcgatcatcgacgagttcatcagc
tccggtgaggccaagtggggccaattgtccaacgtcgtgctgctgttaccgcacgggcac
gaggggcagggacccgaccacacttctgcccggatcgaacgcttcttgcagttgtgggcg
gaaggttcgatgaccatcgcgatgccgtcgactccgtcgaactacttccacctgctacgc
cggcatgccctggacggcatccaacgcccgctgatcgtgttcacgcccaagtcgatgttg
cgtcacaaggccgccgtcagcgaaatcaaggacttcaccgagatcaagttccgctcagtg
ctggaggaacccacctatgaggacggcatcggagaccgcaacaaggtcagccggatcctg
ctgaccagtggcaagctgtattacgagctggccgcccgcaaggccaaggacaaccgcaat
gacctcgcgatcgtgcggcttgaacagctcgccccgctgcccaggcgtcgactgcgtgaa
acgctggaccgctacgagaacgtcaaggagttcttctgggtccaagaggaaccggccaac
cagggtgcgtggccgcgattcgggctcgaactacccgagctgctgcctgacaagttggcc
gggatcaagcgaatctcgcgccgggcgatgtcagccccgtcgtcaggctcgtcgaaggtg
cacgccgtcgaacagcaggagatcctcgacgaggcgttcggctga
DBGET
integrated database retrieval system
