KEGG T01575: MAF

Mycobacterium tuberculosis variant africanum: MAF_29920

Entry

MAF_29920         CDS       T01575

Symbol

leuD

Name

(GenBank) putative 3-isopropylmalate dehydratase (small subunit) LEUD (isopropylmalate isomerase)

K01704

3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]

Organism

maf Mycobacterium tuberculosis variant africanum

Pathway

maf00290

Valine, leucine and isoleucine biosynthesis

maf00660

C5-Branched dibasic acid metabolism

maf01100

Metabolic pathways

maf01110

Biosynthesis of secondary metabolites

maf01210

2-Oxocarboxylic acid metabolism

maf01230

Biosynthesis of amino acids

Module

maf_M00432

Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate

Brite

KEGG Orthology (KO) [BR:maf00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    MAF_29920 (leuD)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    MAF_29920 (leuD)
Enzymes [BR:maf01000]
4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     MAF_29920 (leuD)
    4.2.1.35  (R)-2-methylmalate dehydratase
     MAF_29920 (leuD)

SSDB

Motif

Pfam:

Aconitase_C

Other DBs

NCBI-ProteinID:

CCC28062

LinkDB

Position

complement(3322972..3323568)

AA seq 198 aa
MEAFHTHSGIGVPLRRSNVDTDQIIPAVFLKRVTRTGFEDGLFAGWRSDPAFVLNLSPFD
RGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFGDIFRGNAGKAGLLAAEVAQDDV
ELLWKLIEQSPGLEITANLQDRIITAATVVLPFKIDDHSAWRLLEGLDDIALTLRKLDEI
EAFEGACAYWKPRTLPAP

NT seq 597 nt +upstreamnt +downstreamnt
atggaagcctttcacacccactctggtattggcgtgccgttgcggcggtccaatgtcgac
accgatcagatcattcccgcggtctttctgaagcgggtcacccgaaccggtttcgaggac
ggcttgttcgcgggttggcggtcggatcctgcattcgtgctaaacctcagtccctttgac
cggggttcggtcctggttgccgggcccgatttcggcaccggatcctcgcgagagcatgcg
gtctgggcgctcatggactacggattccgggtggttatctcatcccgatttggtgacatt
ttccgcggcaacgcgggcaaggccgggctgctggcggccgaggttgcccaagacgatgtg
gaactcctgtggaagctcattgagcagagtccgggcctggaaatcactgccaatcttcaa
gatcgaattatcaccgcagcaacagtggtgctgccgttcaagattgacgaccactcggcg
tggcggctgcttgaaggtctcgacgatatagcccttacgctgcggaaactcgacgagatc
gaggcctttgagggtgcgtgcgcgtactggaaaccgcgcactctacccgccccctga

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