Entry Name ABC transporters - Magnetospirillum sp. XM-1
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Other DBs Organism Magnetospirillum sp. XM-1 [GN:
magx ]
Gene XM1_0143 nrtC; Nitrate transporter substrate-binding protein [KO:K15576 ]
XM1_0144 nrtB; Nitrate transporter integral membrane protein [KO:K15577 ]
XM1_0768 pstB; phosphate transporter subunit; ATP-binding component of ABC superfamily [KO:K02036 ] [EC:7.3.2.1 ]
XM1_0934 pstC; Phosphate ABC transporter, inner membrane subunit PstC [KO:K02037 ]
XM1_0936 pstB; phosphate transporter subunit; ATP-binding component of ABC superfamily [KO:K02036 ] [EC:7.3.2.1 ]
XM1_1188 ccmA; Cytochrome c biogenesis ATP-binding export protein CcmA(ABC transporter, haem export, CcmA,11-211) [KO:K02193 ] [EC:7.6.2.5 ]
XM1_1189 ccmB; heme exporter subunit; membrane component of ABC superfamily(Cytochrome c-type biogenesis protein CcmB, bacteria,7-217) [KO:K02194 ]
XM1_1196 ccmC; heme exporter subunit; membrane component of ABC superfamily(Cytochrome c-type biogenesis protein CcmC,41-2254) [KO:K02195 ]
XM1_1202 cbiM; Cobalt transport protein CbiM(Cobalamin (vitamin B12) biosynthesis protein CbiM,1-209) [KO:K02007 ]
XM1_1203 cbiN; Cobalt transport protein CbiN(Cobalt transport protein CbiN,6-71) [KO:K02009 ]
XM1_1372 fbpA; Iron(III) ABC transporter, periplasmic iron(III)-binding protein [KO:K02012 ]
XM1_1418 lptB; lipopolysaccharide transport protein B: ATP-binding component of ABC superfamilyABC transporter-like,68-189) [KO:K06861 ] [EC:7.5.2.5 ]
XM1_1578 gltI; glutamate and aspartate transporter subunit; periplasmic-binding component of ABC superfamily(Extracellular solute-binding protein, family 3,36-265) [KO:K10001 ]
XM1_1682 livF; leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily(ABC transporter-like,55-181) [KO:K01996 ]
XM1_1709 cysP; thiosulfate transporter subunit; periplasmic-binding component of ABC superfamily(Thiosulphate/Sulfate-binding protein,4-341) [KO:K02048 ]
XM1_1710 cysU; sulfate/thiosulfate transporter subunit; membrane component of ABC superfamily(Sulphate ABC transporter, permease protein CysT,7-270) [KO:K02046 ]
XM1_1711 cysW; sulfate/thiosulfate transporter subunit; membrane component of ABC superfamily(Sulphate ABC transporter, permease protein CysW,20-275) [KO:K02047 ]
XM1_1821 gltK; glutamate and aspartate transporter subunit; membrane component of ABC superfamily（Amino acid ABC transporter, permease protein, 3-TM domain, His/Glu/Gln/Arg/opine family,14-112） [KO:K10002 ]
XM1_1822 gltL; glutamate/aspartate transport protein (ABC superfamily, atp_bind)（ABC transporter-like,41-165） [KO:K10004 ] [EC:7.4.2.1 ]
XM1_1998 pstB; high-affinity phosphate transport protein (ABC superfamily, atp_bind)（Phosphate transport system permease protein 1,12-259） [KO:K02036 ] [EC:7.3.2.1 ]
XM1_1999 pstA; Phosphate ABC transporter, permease protein PstA（Phosphate transport system permease protein PstA,185-424） [KO:K02038 ]
XM1_2000 pstC; Phosphate ABC transporter, permease protein PstC（Phosphate ABC transporter, permease protein PstC,159-452） [KO:K02037 ]
XM1_2724 cysP; sulfate transport protein (ABC superfamily, peri_bind) [KO:K23163 ]
XM1_2725 cysT; sulfate transport protein (ABC superfamily, membrane) [KO:K02046 ]
XM1_2726 cysW; sulfate transport protein (ABC superfamily, membrane) [KO:K02047 ]
XM1_2746 livF; leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily [KO:K01996 ]
XM1_2747 braF; putative High-affinity branched-chain amino acid transport ATP-binding protein BraF [KO:K01995 ]
XM1_2790 braF; putative leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily [KO:K01995 ]
XM1_3213 livF; leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily [KO:K01996 ]
XM1_3214 livG; leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily [KO:K01995 ]
XM1_3324 livG; ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01995 ]
XM1_3325 livF; leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily [KO:K01996 ]
XM1_3342 znuB; zinc transporter subunit: membrane component of ABC superfamily [KO:K09816 ]
XM1_3345 znuA; High-affinity zinc uptake system protein ZnuA [KO:K09815 ]
XM1_3380 lolD; outer membrane-specific lipoprotein transporter subunit; ATP-binding component of ABC superfamily [KO:K09810 ] [EC:7.6.2.-]
XM1_3381 LolC; ABC-type transport system, permease component,Lipoprotein ABC transporter; permease component LolC [KO:K09808 ]
XM1_3416 livF; High-affinity branched-chain amino acid transport ATP-binding protein LivF,leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily [KO:K01996 ]
XM1_3435 potI; putrescine transporter subunit: membrane component of ABC superfamily [KO:K11074 ]
XM1_3436 potH; putrescine transporter subunit: membrane component of ABC superfamily [KO:K11075 ]
XM1_3437 potG; putrescine transporter subunit: ATP-binding component of ABC superfamily [KO:K11076 ] [EC:7.6.2.16 ]
XM1_3438 potF; putrescine transporter subunit: periplasmic-binding component of ABC superfamily [KO:K11073 ]
XM1_3618 livH; leucine/isoleucine/valine transporter subunit; membrane component of ABC superfamily [KO:K01997 ]
XM1_3619 livM; leucine/isoleucine/valine transporter subunit; membrane component of ABC superfamily [KO:K01998 ]
XM1_3620 livG; leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily [KO:K01995 ]
XM1_3621 livF; leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily [KO:K01996 ]
XM1_3876 livK; leucine transporter subunit; periplasmic-binding component of ABC superfamily [KO:K01999 ]
XM1_3892 livF; leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily [KO:K01996 ]
XM1_3893 livG; leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily [KO:K01995 ]
XM1_4280 modB; molybdate transporter subunit (membrane component of ABC superfamily) [KO:K02018 ]
XM1_4281 modC; molybdate transporter subunit modC (ATP-binding component of ABC superfamily) [KO:K02017 ] [EC:7.3.2.5 ]
XM1_4550 modA; molybdate transporter subunit; periplasmic-binding component of ABC superfamily [KO:K02020 ]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway
