Mirounga angustirostris (Northern elephant seal): 123834201
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Entry
123834201 CDS
T11530
Symbol
HSD11B1L
Name
(RefSeq) hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X3
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
mano Mirounga angustirostris (Northern elephant seal)
Pathway
mano00140
Steroid hormone biosynthesis
mano00980
Metabolism of xenobiotics by cytochrome P450
mano01100
Metabolic pathways
mano05204
Chemical carcinogenesis - DNA adducts
Module
mano_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
mano00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
123834201 (HSD11B1L)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
123834201 (HSD11B1L)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
123834201 (HSD11B1L)
Enzymes [BR:
mano01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
123834201 (HSD11B1L)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
Peripla_BP_6
Motif
Other DBs
NCBI-GeneID:
123834201
NCBI-ProteinID:
XP_045719192
LinkDB
All DBs
Position
Unknown
AA seq
286 aa
AA seq
DB search
MKVLLLTGLGALFFSYYWDDNFDPAGLQGARVLLTGASAGIGEELAYLYARLGAHLVLTA
HTEALLQKVVGNCRKLGAPKVFFIAADMASPEVPERVVRFALDKLGGLDYLVLNHLGTPA
GTRSRSVQATRWLLQVNFLSYVQLTSLALPSLTDSKGSLVVVSSLLGHVPTSFSSPYSAA
KFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASTAEGVRGVTRAKAAPGPKAALAVI
RGGATRAPGVFYPWRFHLLCLLRGWLPHPRAWFIRQELNVTAAEAA
NT seq
861 nt
NT seq
+upstream
nt +downstream
nt
atgaaggttctgctcctcaccggactgggggccctgttcttctcctactattgggatgac
aacttcgaccctgctggcctgcagggagcccgagtgctgctgaccggggccagcgcgggc
attggggaggagctggcttatctctacgcacgcctgggcgcccacctggtgctcacggcc
cacaccgaggccctcctacagaaggtggtagggaactgccggaagctgggcgctcccaag
gtcttcttcatcgctgcggacatggcctcccctgaggtgcccgagcgcgtggtgcggttt
gcgctggacaagctgggagggctggactacctcgtgctgaaccacctcggcaccccggca
ggcacgcggtcccggagcgtccaggcgacacgctggctcctgcaggtgaacttcctgagt
tacgtgcagctgacttcgttggcgctgcccagcctgacggacagcaaaggctctctggtg
gtcgtgtcctcgctgctcggccatgtgcccacatccttctccagcccgtactcggcggcc
aagttcgcgctggacggcttcttcggctctctgcggcgggagctggacgtgcaggacgtg
aacgtggccatcaccatgtgtgtcctgggcctccgggatcgcgcctcgactgccgaggga
gtcaggggcgtcacgagggccaaggcggccccagggcccaaggcagccctggccgtgatc
cgcggcggcgccacacgcgcccctggcgtcttctacccgtggcgcttccacctgctctgc
ctgctccggggatggctgccgcacccgagggcttggttcatccgccaggagctcaacgtc
accgctgccgaggctgcctga
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