KEGG   MODULE: many_M00978
Entry
many_M00978       Pathway   Module                                 
Name
Ornithine-ammonia cycle
Definition
K01915 K01955+K01956 K00611 K01940 K01755 (K27542,K27545)
Diagram
many_M00978  Ornithine-ammonia cycle
many_M00978

Class
Pathway modules; Amino acid metabolism; Arginine and proline metabolism
Pathway
many00220  Arginine biosynthesis
many01100  Metabolic pathways
many01110  Biosynthesis of secondary metabolites
Organism
Mycolicibacterium anyangense [GN:many]
Gene
MANY_00970  glutamine synthetase [KO:K01915]
MANY_05670  glutamate--ammonia ligase [KO:K01915]
MANY_10010  carA; carbamoyl-phosphate synthase small chain [KO:K01956]
MANY_10020  carB; carbamoyl-phosphate synthase large chain [KO:K01955]
MANY_14550  glnA4; glutamine synthetase [KO:K01915]
MANY_14670  glnA3_1; glutamine synthetase GlnA [KO:K01915]
MANY_16440  argH; argininosuccinate lyase [KO:K01755]
MANY_16450  argG; argininosuccinate synthase [KO:K01940]
MANY_16470  argF; ornithine carbamoyltransferase [KO:K00611]
MANY_18550  glnA_1; glutamine synthetase 1 [KO:K01915]
MANY_18660  glnA_2; putative glutamine synthetase 2 [KO:K01915]
MANY_20160  type III glutamate--ammonia ligase [KO:K01915]
MANY_20770  glnN; glutamine synthetase [KO:K01915]
MANY_35040  glnT; glutamine synthetase [KO:K01915]
MANY_47780  glnA3_2; glutamine synthetase GlnA [KO:K01915]
MANY_49560  amidinotransferase [KO:K27545]
Reaction
R00253  
R00575  
R01398  
R01954  
R01086  
R13308  
Compound
C00014  Ammonia
C00064  L-Glutamine
C00169  Carbamoyl phosphate
C00327  L-Citrulline
C03406  N-(L-Arginino)succinate
C00062  L-Arginine
C00011  CO2
Reference
PMID:29632414
  Authors
Zhang H, Liu Y, Nie X, Liu L, Hua Q, Zhao GP, Yang C.
  Title
The cyanobacterial ornithine-ammonia cycle involves an arginine dihydrolase.
  Journal
Nat Chem Biol 14:575-581 (2018)
DOI:10.1038/s41589-018-0038-z
KO module
M00978
LinkDB

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