Entry
Name
Lysine biosynthesis
Class
Metabolism; Amino acid metabolism
BRITE hierarchy
Pathway map
Ortholog table
Module
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:map00300 ]
M00030 Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine [PATH:map00300 ]
M00031 Lysine biosynthesis, mediated by LysW, 2-aminoadipate => lysine [PATH:map00300 ]
M00433 Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate [PATH:map00300 ]
M00525 Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine [PATH:map00300 ]
M00526 Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine [PATH:map00300 ]
M00527 Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine [PATH:map00300 ]
M00608 2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate [PATH:map00300 ]
Other DBs
Reference
Authors
Ledwidge R, Blanchard JS.
Title
The dual biosynthetic capability of N-acetylornithine aminotransferase in arginine and lysine biosynthesis.
Journal
Reference
Authors
Fuchs TM, Schneider B, Krumbach K, Eggeling L, Gross R.
Title
Characterization of a bordetella pertussis diaminopimelate (DAP) biosynthesis locus identifies dapC, a novel gene coding for an N-succinyl-L,L-DAP aminotransferase.
Journal
Reference
Authors
Zabriskie TM, Jackson MD.
Title
Lysine biosynthesis and metabolism in fungi.
Journal
Reference
Authors
Rodionov DA, Vitreschak AG, Mironov AA, Gelfand MS.
Title
Regulation of lysine biosynthesis and transport genes in bacteria: yet another RNA riboswitch?
Journal
Reference
Authors
Velasco AM, Leguina JI, Lazcano A.
Title
Molecular evolution of the lysine biosynthetic pathways.
Journal
Reference
Authors
Miyazaki T, Miyazaki J, Yamane H, Nishiyama M.
Title
alpha-Aminoadipate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus.
Journal
Reference
Authors
Goh DL, Patel A, Thomas GH, Salomons GS, Schor DS, Jakobs C, Geraghty MT.
Title
Characterization of the human gene encoding alpha-aminoadipate aminotransferase (AADAT).
Journal
Reference
Authors
Nishiyama M.
Title
[Novel lysine biosynthesis: a key to elucidate evolution of metabolic and biosynthetic pathways]
Journal
Tanpakushitsu Kakusan Koso 49:758-63 (2004)
Reference
Authors
Nishida H, Nishiyama M, Kobashi N, Kosuge T, Hoshino T, Yamane H.
Title
A prokaryotic gene cluster involved in synthesis of lysine through the amino adipate pathway: a key to the evolution of amino acid biosynthesis.
Journal
Reference
Authors
Sakai H, Vassylyeva MN, Matsuura T, Sekine S, Gotoh K, Nishiyama M, Terada T, Shirouzu M, Kuramitsu S, Vassylyev DG, Yokoyama S.
Title
Crystal structure of a lysine biosynthesis enzyme, LysX, from Thermus thermophilus HB8.
Journal
Reference
Authors
Hudson AO, Singh BK, Leustek T, Gilvarg C.
Title
An LL-diaminopimelate aminotransferase defines a novel variant of the lysine biosynthesis pathway in plants.
Journal
Reference
Authors
Horie A, Tomita T, Saiki A, Kono H, Taka H, Mineki R, Fujimura T, Nishiyama C, Kuzuyama T, Nishiyama M
Title
Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus.
Journal
Reference
Authors
Dairi T, Kuzuyama T, Nishiyama M, Fujii I
Title
Convergent strategies in biosynthesis.
Journal
Reference
Authors
Gaston MA, Jiang R, Krzycki JA
Title
Functional context, biosynthesis, and genetic encoding of pyrrolysine.
Journal
Related pathway
map00250 Alanine, aspartate and glutamate metabolism
map00260 Glycine, serine and threonine metabolism
map00960 Tropane, piperidine and pyridine alkaloid biosynthesis
KO pathway
LinkDB
All DBs