KEGG   PATHWAY: map00997
Entry
map00997                    Pathway                                
Name
Biosynthesis of various other secondary metabolites
  Including
Ditryptophenaline biosynthesis, Fumiquinazoline D biosynthesis, Paerucumarin biosynthesis, Staphyloferrin B biosynthesis, Cyclooctatin biosynthesis, Lovastatin biosynthesis, Grixazone biosynthesis, Staphyloferrin A biosynthesis, Ethynylserine biosynthesis, Aerobactin biosynthesis
Class
Metabolism; Biosynthesis of other secondary metabolites
Pathway map
map00997  Biosynthesis of various other secondary metabolites
map00997

Module
M00875  Staphyloferrin B biosynthesis, L-serine => staphyloferrin B [PATH:map00997]
M00876  Staphyloferrin A biosynthesis, L-ornithine => staphyloferrin A [PATH:map00997]
M00891  Ditryptophenaline biosynthesis, tryptophan + phenylalanine => ditryptophenaline [PATH:map00997]
M00893  Lovastatin biosynthesis, malonyl-CoA => lovastatin acid [PATH:map00997]
M00901  Fumiquinazoline biosynthesis, tryptophan + alanine + anthranilate => fumiquinazoline [PATH:map00997]
M00905  Grixazone biosynthesis, aspartate 4-semialdehyde => grixazone B [PATH:map00997]
M00906  Ethynylserine biosynthesis, lysine => ethynylserine [PATH:map00997]
M00918  Aerobactin biosynthesis, lysine => aerobactin [PATH:map00997]
M00921  Cyclooctatin biosynthesis, dimethylallyl-PP + isopentenyl-PP => cyclooctatin [PATH:map00997]
Reference
  Authors
Saruwatari T, Yagishita F, Mino T, Noguchi H, Hotta K, Watanabe K
  Title
Cytochrome P450 as dimerization catalyst in diketopiperazine alkaloid biosynthesis.
  Journal
Chembiochem 15:656-9 (2014)
DOI:10.1002/cbic.201300751
Reference
  Authors
Lim FY, Ames B, Walsh CT, Keller NP
  Title
Co-ordination between BrlA regulation and secretion of the oxidoreductase FmqD directs selective accumulation of fumiquinazoline C to conidial tissues in Aspergillus fumigatus.
  Journal
Cell Microbiol 16:1267-83 (2014)
DOI:10.1111/cmi.12284
Reference
  Authors
Clarke-Pearson MF, Brady SF
  Title
Paerucumarin, a new metabolite produced by the pvc gene cluster from Pseudomonas  aeruginosa.
  Journal
J Bacteriol 190:6927-30 (2008)
DOI:10.1128/JB.00801-08
Reference
  Authors
Cheung J, Beasley FC, Liu S, Lajoie GA, Heinrichs DE
  Title
Molecular characterization of staphyloferrin B biosynthesis in Staphylococcus aureus.
  Journal
Mol Microbiol 74:594-608 (2009)
DOI:10.1111/j.1365-2958.2009.06880.x
Reference
  Authors
Kim SY, Zhao P, Igarashi M, Sawa R, Tomita T, Nishiyama M, Kuzuyama T
  Title
Cloning and heterologous expression of the cyclooctatin biosynthetic gene cluster afford a diterpene cyclase and two p450 hydroxylases.
  Journal
Chem Biol 16:736-43 (2009)
DOI:10.1016/j.chembiol.2009.06.007
Reference
  Authors
Xu W, Chooi YH, Choi JW, Li S, Vederas JC, Da Silva NA, Tang Y
  Title
LovG: the thioesterase required for dihydromonacolin L release and lovastatin nonaketide synthase turnover in lovastatin biosynthesis.
  Journal
Angew Chem Int Ed Engl 52:6472-5 (2013)
DOI:10.1002/anie.201302406
Reference
  Authors
Suzuki H, Ohnishi Y, Furusho Y, Sakuda S, Horinouchi S
  Title
Novel benzene ring biosynthesis from C(3) and C(4) primary metabolites by two enzymes.
  Journal
J Biol Chem 281:36944-51 (2006)
DOI:10.1074/jbc.M608103200
Reference
  Authors
Cotton JL, Tao J, Balibar CJ
  Title
Identification and characterization of the Staphylococcus aureus gene cluster coding for staphyloferrin A.
  Journal
Biochemistry 48:1025-35 (2009)
DOI:10.1021/bi801844c
Reference
  Authors
Marchand JA, Neugebauer ME, Ing MC, Lin CI, Pelton JG, Chang MCY
  Title
Discovery of a pathway for terminal-alkyne amino acid biosynthesis.
  Journal
Nature 567:420-424 (2019)
DOI:10.1038/s41586-019-1020-y
Reference
PMID:1393837
  Authors
Neilands JB
  Title
Mechanism and regulation of synthesis of aerobactin in Escherichia coli K12 (pColV-K30).
  Journal
Can J Microbiol 38:728-33 (1992)
DOI:10.1139/m92-119
Related
pathway
map00010  Glycolysis / Gluconeogenesis
map00020  Citrate cycle (TCA cycle)
map00250  Alanine, aspartate and glutamate metabolism
map00260  Glycine, serine and threonine metabolism
map00400  Phenylalanine, tyrosine and tryptophan biosynthesis
map00900  Terpenoid backbone biosynthesis
KO pathway
ko00997   
LinkDB

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