Myxocyprinus asiaticus (Chinese sucker): 127433765 Help Entry 127433765         CDS       T08782                                  Name (RefSeq) ryanodine receptor 1   KO K04961   ryanodine receptor 1 Organism masi  Myxocyprinus asiaticus (Chinese sucker) Pathway masi04020   Calcium signaling pathway masi04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:masi00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     127433765    04020 Calcium signaling pathway     127433765  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:masi01009]     127433765   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:masi04147]     127433765    04040 Ion channels [BR:masi04040]     127433765 Protein phosphatases and associated proteins [BR:masi01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      127433765 Exosome [BR:masi04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    127433765 Ion channels [BR:masi04040]  Voltage-gated cation channels   Ryanodine receptor    127433765 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 Ins145_P3_rec MIR SPRY RIH_assoc Ion_trans EF-hand_7 Motif Other DBs NCBI-GeneID:  127433765 NCBI-ProteinID:  XP_051541905 LinkDB All DBs Position 43:25843211..25928355 Genome browser AA seq 5011 aa AA seqDB search MAEGGDGEEEIQFLRTDDQVVLQCTATILKEQIKLCLSCEGFGNRLCFLETTSNAQNVPP DLAICCFILEQSLSVRALQEMLANTTELNESSQGGGHRTLLYGHAILLRHTHSGMYLSCL TTSRSLTDKLAFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLH LSYASGDLMVDASFMQTLWNMNPVCSGCELAEGYLTGGHVLRLFHGHMDECLTIPGADQG DDQRRNAHYEGGAVCSHARSLWRLEPLRIGWSGSHMKWGQSFRVRHITTGRYLCLDEEKG LLLVDPEKANTKNSAFCFRASKEKTEVAQKRDVEGMGIPEIKYGESMCFVQHVSTSLWLT YASVDAKSARLGPLKRKAILHQEGHMDDALTVARSQTAESQAARMIYSTAGLFTQFIKGL DSLSGKSKSPPPTPSLPLDSVVLSLQDLIFYFRPPEEELEHEEKQTKLRSLRNRQNLFQE EGMISLVLDCVDRLNVYNTAAHFSEFAGEEAAESWKEIVNLLYELLASLIRGNRANCALF CDNLDWLVSKLDRLEASSGILEVLYCILIESPEVLNIIQENHIKSIIALLDKHGRNHKVL DVLCSLCVCNGVAVRSNQNLITENLLPGRDLLLQTNIINYVTSMRPNIFLGTCEGSTQYK KWYFEIIVDHVESFLTPQPCHLRVGWALTEGYSPYPGGGEGWGSNGVGDDLYSYGFDGLH LWTGRVPRQVTSPSQHILAAEDVVSCCLDLSVPSISFRINGHPVQGMFENFNLDGLFFPV VSFSAGIRVRFLLGGRHGDFKFLPPPGYAPCYEAVLPKDRLRIEPIKEYKHDFNDVRNLL GPTQSLSHTAFTPCPVDTVQIVLPPHLERIREKLAENSHELWAITRIEQGWTYGPFRDDN KKLHPCLVDFQSLPEPEKNYNLAMSGETLKTLLALGCHVGMGDEKAEENLKKIKLPKTYM QSNGYKPAPLDLNHVKLTPNQNTLVERLAENGHNVWARDRVRQGWTYSIIQDIVNKRNPR LVPYILLDEKTKKTNRDSVCAAVRTLIGYGYNIEPPDQESGHGAGSGRSDKIRVFRAEKS YAVTQGKWYFEFEAVTVGEMRVGWARPNVHADKELGSDELAYVFNGFKAQRWHVGNEPFG RQWQSGDVVGCMIDLTEQNIMFTLNGEMLISDSGSEMAFKDIEIGEGFIPVCSLGLSQVG RINLGQNVSSLRYFTICGLQEGFEPFAINMKRDITMWFSKSLPQFVPVPTEHPHIEVSRV DGTVDSAPCLKLTHKTFGSQNANTDLLFFRLSMPIEFHETFKVPVGTTPLTRTLTIPEDE TLEVDPESEFELLKKSATRKEQDEKEKEPSVPKDLPGNKEGENEKDTTTEKSKKRGFFSK AKKAAFIAPPPVVPTVPRLMEDVVPDDRDDADIISNTTTYYYSVRMFAGQEPSGVWVGWV TPDYHLYDLHFDLGKVRNVTVTIGDDKGNIHDSVKRSNCYMVWGGEFSSSQQARISQEDF VIGCLVDLDTGLMTFTANGKEINTFYQVEPNTKLFPALFCVPSSQNMLQVELGKLKNIMP ISAAMFRSDNKNPVPQCPPRLDVQMLTPVIWSRMPNHFLAPETGRVSERQGWKVQCTEPL IMMALHIPEENRCIDILELSEHTDLMKFHYHTLKLYGSVCALGNNRVAHALCSHVDESQL FYAIENTFLPGPIRSGYYDLLISMHLESAKRNRLMTNKEFIVPMTDETRSITLYSDAEKA HALPGVGLTTCLRPKLHFSPTGFVGTNADIYTLSPVLPLQMLKDHALSMLTEAVQDGGQA MRDPVGGSVEFHFVPILKLISTLLIMGVFDDSDVKHILKLIEPSVFNNDAEKELEPEEEE YEDQVVKEGEESEHDAEKADREKTTDGEVEEAGLAEAEIKEEDVGEGLLHMKLPESVKLQ MCTLLQYFCDCELRHRVEAIIAFSDKFVNQVQTNQRQRYNELMQAFTMSAAETARKTREF RSPPQEQVNMLMNFKNCPEEEECPVPVGVRNDLLTFHHDLLAHCGVHIEEEEEEEEVDNS VRGRLLRLVDKVKNLRKKPEAEPEPEEDKKPSTLQELISHTMIHWAQESFIQNPELVRLM FSLLHRQYDALGELIRALPKAYIINAVSVQDTMELLECLGQIRSLLIVQMGPEEERLMIQ SIGNIMSNRVFYQHPNLMRALGMHETVMEVMVNVLGGGDSKEIRFPRMVTNCCRFLCYFC RISRQNQRSMFDHLGYLLQNSGIGLGMRGSTPLDVAAASCIDNNELALALQEQDLEMVVK YLAGCGLQSCPMLLSKGYPDIGWNPCGGEKYLDFLRFAVFVNGESVEENANVVVRLLIRR PECFGPALRGEGGNGLLAAIEEAIKISEDPARDGPTVKKDRRFPMFGGEEQHEENRVHLG NAIMSFYSALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPIEDLVGVISLPVQIPAL GKDNSIIEPKMSASFVPDHKAPMVLFLDRVYGIDNQDFLLHVLEVGFLPDMRAAASLDTA AFSTTEMALALNRYLCSAVLPLITKCAPLFAGTDHRAIMIDSMLHTIYRLSRGRSLTKAQ RDVIEECLMSLCRYLRPSMLQHLLRRLVFDVPILNEYAKMPLKLLTNHYERCWKYYCLPN GWANFGISSEEELHLTRKLFWGIFESLAHKKFDAELFKIAMPCICAIAGAIPPDYVDASY SSKTEKKASVDAEGNFDPKPVDTTNTIIPEKLDGFINRYAEYTHDKWAFEKIQNNWTFGE LLDENAKTHPMLRPYKTFSEKDKEIYRWPIKESIKAMIAWEWTLDKARDGEDEKTEKKTT RKISQTAQATYDPSHGYSPQPIDISGMTLSRELQSMAEQLAENYHNTWGRKKKMELQSKG GGTHPLLVPYDTLTAKEKARDREKAHELLKFLQLNGYAVTRGLKDMESDISSIEKRFAYG FLQKLLKWMDIAQEFIAHLEAVVSSGRVEKSPHEQEIKFFAKILLPLINQYFKNHCLYFL STPAKILGSGGHASNKEKEMIASIFCKMSALVRHRVFLFGTDASAIVNCLHILARSLDAR TVMKSGPEIVKAGLRSFYESAADDIEKMVENLKLGKVSKGNQPVKGVSQNINYTTIALLP VLTSLFDHIAQHQFGDDVILDDLQMSCYRIMCSIYSLGTVKTPHAERHRPALGECLAHLA AAMPVAYLEPHLNEYNAFSVYTTKTPRERAILGLPNHVKELCLDIPELEILMKEIGDLAE SGARYTEMPHVIEVTLPMLCNYLPRWWERGVENFPESEGKLCTDVTSDQLNQLLGSIMKI VVNNLGIDEASWMKRLAVFSQPIVSRAKPEMLKSHFIPTMEKLKKRTSKVVAEEEHLRME GKSEGDEEEGTIRDEFAVLCRDLYALYPLLIRYVDNNRARWLTCRDPDAEELFRMVGEVF IFWSKSHNFKREEQNFVVMNEINNMSFLTADSKSKMSKTGDSEAGGSDVERTKKKRRGDR YSVQTSLIVAALKKMLPIGLNMCSPADQELINLAKTRYSLKDTDEEVREFLQNNLHLQGK VDNPSMRWQMALYKEMAGKAEDADAPEKVVKRVQEVSAVLYHIEVTEHPFKSKKMVWHKL LSKQRRRAVVACFRMTPLYNLPRHRASNMFLDGYKRNWIQTEGYSFEDRMIDDLSKAMEE EEEEEEERETKPDPLHQLILHFSRTALTEKSKLDIDYLYMAYADIMAKSCHMGEEDEGGD EEVEGGEEEMPFEEKEMEKQRLLYQQSRLHNRGAAEMVLQMISACKGETGCMVSSTLKLG ISILNGGNSEVQQKMLDYLKDKKDVGFFLSVQALMQTCSVLDLNAFERQNKAEGLGMVSE EGTNMKLERGEKVMADDEFTCDLFRFLQLLCEGHNNDFQNYLRTQTGSTTTINIIICTVD YLLRLQESISDFYWYYSGKDIIDEPGKRNFSKAMAVAKQVFNSLTEYIQGPCTGNQQSLA HSRLWDAVVGFLHVFAHMMMKLAQDSSQIGLLKELLDLQKDMVVMLLSLLEGNVVNGTIA RQMVDMLVESSSNVEMILKFFDMFLKLKDIVASDAFRDYVTDPRGLISKKDFQKAMDSQK QYTPSEIQFLLSCSEADENEMINYEEFASRFQEPAKDIGFNIAVLLTNLSEHVPHDTRLQ NFLEQAESVLNYFRPFLGRIEIMGASRKIERIYFEISEVNRKQWEMPQVKESKRQFIFDV VNEGGESEKMELFVNFCEDTIFEMNIASQISEQEEEEKEEDDNEEPEGGDGGGSDEEGGG EEGQPESSSAFADFIKSIMNFLGLFNFRNIRRQYRRLRKMTIKEIVVGLATFLWTILMGI LHFIYSVCKGFFLLIWQTLFGGGLVEGAKNITVTEILASMPDPTQDEVHGDLPGEPRGGE EQEMGGITDSMDAGGGEEEDEDIQEKDGGKIPGIDTPGGLGDMGDTTPVEPPTPEGTPLL KRKMQPEEAGPEQPPAIEEPPPEPEKADTENGEKAGKELEAKPETTPKEPKMAKATKTKK EKRSAKGAGFELWNELDVQRNKFMNCLSRNFYNLRFLALFIAFALNFILLFYKVSDTPPD VEEFEGSGLFEGSGLFESSGEEVEGSGGEDVGDDDEEGPVYYFLEESTGYMQPTLSFLAI LHTVIAFISIIGYNCLKIPLVIFKREKELARKLEFDGLYITEQPEDDDIKGQWDRLVLNT PSFPSNYWDKFVKRKVLDKYGDIYGRERIAELLGMDLASLDVSKQQTDKKPEEPDNSILA WLTAIDIKYQVWKFGVVFTDNTFLYLVWYTVMSLLGHYNNFFFACHLLDIAMNVKTLRTI LSSVTHNGKQLMMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFH MYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQ QEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQ ESYVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 15036 nt NT seq  +upstreamnt  +downstreamnt atggcagagggaggggatggagaggaggaaattcagttcttacgaacggatgatcaggtc gttctacagtgcacagccactatcctgaaagagcagattaaactctgtctgtcctgtgag ggttttggaaatcgcctatgtttcctagaaaccacatccaatgcccagaatgttccaccg gatctggctatatgctgctttatcctggaacagtccttatctgttcgagcccttcaggaa atgctggctaacacaactgagctcaacgagtcttcacaaggaggaggccaccgcacgttg ttgtatggccatgccatcctgctcagacacacacactctggcatgtatcttagctgtctg acaacatcaaggtcactcacagacaagctggcctttgacgtaggcttgcaggaggactca acaggtgaggcatgttggtggaccattcatcctgcttccaagcagaggtcagaaggtgag aaggtcagagtcggtgacgacctcatcctggtcagtgtgtcatctgagagatacctgcac ctttcctatgccagtggagacctcatggttgatgcctccttcatgcaaaccctttggaac atgaacccagtctgttctggctgtgagctggcagagggttatctgaccggagggcatgtt ctacgtcttttccacggtcacatggatgagtgtttaacaattcctggtgctgaccagggg gatgaccagagaagaaatgcacactatgaaggtggagctgtgtgtagccacgccagatct ctttggaggctagaacctcttcggattggatggagtggaagccacatgaagtggggtcag tcattcagggtgcgtcacatcaccacaggcaggtatctttgcctggatgaagagaaagga ctcctactcgtggatccagaaaaggcaaatacaaagaattctgccttctgcttccgtgct tcaaaggagaagactgaggtggctcagaaacgtgatgtggagggaatgggaattccagag ataaagtacggagagtccatgtgctttgtgcagcatgtctccaccagtctgtggctcacg tatgcctcagtggatgccaagtctgctcgactggggccactgaagaggaaggctatactg catcaggagggtcatatggatgatgctctgactgtggctcgctctcagacagcagaatct caggctgctagaatgatctacagcacagcaggactcttcactcagttcattaaaggtctg gactctctaagtgggaagagtaagtctccgcccccaactccatctctgcctctggactct gtggttctgtccttgcaggatcttatcttctatttccgcccccctgaagaggagctggaa cacgaagaaaagcagaccaaacttcgttctttaaggaaccgtcagaatctattccaagag gagggcatgatcagtcttgtattagactgtgttgatcggctgaatgtctacaacactgca gcccatttctctgagtttgctggggaggaggcagctgagtcctggaaagagatagtcaac ttactttatgagctgctggcatctctgatcagaggaaacagggcaaactgtgctttgttc tgtgataatctggactggttggtcagcaaactggatcgattagaggcctcttcaggcatt ctggaagtgctgtattgtattctcattgaaagtcctgaagtgcttaacatcatccaagag aaccacatcaaatctatcatcgcacttttggataaacatggacgtaatcacaaggttcta gatgtactctgctctttgtgtgtgtgcaatggtgtagccgtgaggtccaatcagaatctt atcactgagaatctgcttccaggtcgtgatctcctcctgcagactaacatcatcaattat gtcaccagtatgagacccaacatttttctgggcacatgtgaaggctctacacagtataag aagtggtacttcgagataattgtagaccatgtggagtcattcctgacccctcaaccgtgt cacctgcgtgttggctgggctttgacagagggctacagcccgtaccctggaggaggagag ggatgggggagcaatggagtcggagatgatctttattcgtatggctttgatgggctacac ctatggacaggtcgtgttccacgtcaggtgacctcacccagtcaacacattcttgcggcc gaggacgtggtgagctgctgtttggatctgagcgtgcccagtatctccttccgtatcaat ggacatcctgtacaaggaatgttcgagaacttcaatctagatggtctattcttccctgtg gtcagcttctcagctggtatcagagttcgctttctccttggtggacgacatggagacttc aaattcctccctcctccaggctatgccccatgctatgaagcagttctgcccaaagacaga ctgcgtattgagcctattaaagagtacaagcatgacttcaatgatgtccggaatcttctg gggccaactcaatctctctcccacaccgccttcactccttgcccggttgacactgtgcag attgtactccctcctcatctggagcgtatcagagagaaactggctgagaatagtcatgag ctgtgggccattacacgtatcgagcagggctggacctatggaccattccgtgatgacaat aagaagctgcacccctgtctagtggacttccagagtcttccagagccggagaagaactac aatctggcaatgtctggagagacactgaagactcttctggctttaggatgtcatgtaggc atgggtgatgagaaagcagaggagaacttgaagaagattaaactccccaaaacgtatatg cagagcaatggctacaaacctgcacctctggacctcaaccatgtgaagctgacacccaat cagaacacacttgtggaaagactggcagaaaatggacacaatgtctgggctcgtgaccgg gtccgccagggctggacttacagcattattcaggatattgtgaacaagcgcaacccccgt cttgtgccttacattcttctggatgaaaagacaaaaaagaccaatcgtgacagtgtatgt gccgctgtacgcactcttattggctatggctacaatattgagccacctgaccaggaaagt ggacatggggctgggagtggccggagtgataagatccgggtgttcagagcagaaaagtcc tacgccgtgacccaggggaaatggtactttgagtttgaggcagtaacagtgggcgagatg agagttgggtgggcaagaccaaatgtccatgcagataaagagctgggatctgatgaactg gcctacgtcttcaatggattcaaggctcagcgctggcatgttgggaatgagccgtttgga cggcagtggcagtctggtgacgtggtgggctgcatgatagacctgacggagcagaacatc atgtttactttgaacggagagatgctcattagtgactctggatctgagatggccttcaaa gacattgagatcggagagggcttcatccctgtatgcagtctggggctttctcaagtgggc cgtattaaccttgggcagaatgtgagcagcctgcgttacttcactatctgtggcctgcag gaaggttttgagcctttcgccatcaacatgaagagagatatcaccatgtggtttagcaag agtttgccccagtttgtgcctgtgccaacagaacaccctcatattgaggtgtcccgtgtg gacggaacggtagacagtgccccttgtctgaaactgacccataagacatttggatctcag aatgccaacacagaccttctgttctttagactgagcatgcctatagaattccacgagacc tttaaagtgccagtgggtacaacacccctcacccgcaccctcactatccctgaggacgag actcttgaggtagacccagaatcagagtttgagcttctgaagaagtcagctactcgcaaa gagcaagatgagaaagaaaaagagccgtccgttcctaaagatctacctggcaacaaagaa ggggagaatgagaaagataccaccacagagaagagcaaaaagagagggttcttttccaag gcaaagaaggcagcgtttatagccccaccaccagtggttccaactgtgcctcgtctgatg gaggacgttgtcccagatgatcgagatgatgctgacattatctcaaacacaacaacttat tattattcagtccggatgtttgcggggcaggagcccagtggagtgtgggtaggctgggtt actcctgattatcacctgtatgaccttcactttgatcttggtaaagtccgaaacgtaact gttactattggggatgataaaggcaacattcatgacagtgtaaagcgcagtaactgctac atggtgtggggaggagagttcagcagttcgcagcaagcacgcattagccaggaggacttt gtgattggctgcttggtggatctggacacaggactcatgaccttcacagccaatgggaaa gagatcaacactttctaccaggtagaacctaacacaaagctgttccctgctttgttttgt gtgccatccagccagaatatgttacaagtggaacttggcaaattaaagaacattatgccc atctctgcagccatgttccgcagtgacaataagaacccagttcctcagtgtcctcccagg ttagatgttcagatgttgactccagtcatatggagccgaatgcctaatcacttcttggcc cctgagactggtcgtgtgagtgagagacaaggctggaaagtgcaatgcactgaacctctc attatgatggcattgcacattccagaagagaacagatgcattgatatcctggagctttct gagcacacagatctgatgaagttccattaccacactctgaaactgtatggctcagtgtgc gctctgggcaacaaccgcgttgcacacgccctctgtagccacgtggacgaatcacagctc ttctatgccatcgagaacaccttcctgcctggccccatccgcagcggttactacgacctg ctcatatccatgcatcttgaatctgccaagcgaaaccgtctaatgaccaataaagagttc attgttcccatgacggatgagacacgtagcatcactctctactcagatgctgagaaggcc catgcgctaccaggagtcggacttaccacctgcctgcgacccaaactacacttctctccc actgggtttgtgggcactaatgcagacatctacaccctcagccccgtcttacctctgcag atgctcaaggaccatgccctcagcatgcttacagaagccgtgcaggacggagggcaggct atgcgtgatcctgtagggggcagcgtcgagttccactttgtgcccatcctgaaactcatc agcaccctgctaataatgggcgtgtttgacgacagcgacgtgaagcacatcctgaagctg atcgagccttctgtgttcaacaatgatgctgagaaggagcttgagcctgaggaggaggaa tatgaagatcaggtggtaaaggaaggggaggagagtgagcatgatgcggaaaaagcggac agagaaaaaacgactgatggagaggtggaggaagctggtctagcagaggcagagataaaa gaggaggatgtgggtgaaggactgctgcacatgaagcttccagagtctgtcaaacttcag atgtgtactctgctgcagtatttttgcgattgtgagctgcgtcacagagtggaagccatc atcgctttctctgacaagtttgtcaaccaagtgcagaccaatcagagacagcgatataac gagctcatgcaggctttcacaatgagtgctgcagaaactgcccgcaagacccgcgaattc cgctctcctccgcaggaacaggtgaacatgttaatgaactttaaaaactgtccagaggag gaagagtgtcctgttcctgtaggtgtccgcaacgacctgctaacattccaccatgacctg ttggctcactgtggtgtgcatattgaagaggaggaggaggaagaagaggtggacaactct gtccgtggacgcctcctgagactggtggataaagttaaaaacttgcgtaagaagccggag gccgagcctgaacctgaagaagataaaaaacccagtactcttcaggagttgatctcccac accatgattcactgggctcaagagtctttcattcagaaccctgaactggtacggcttatg ttcagtctgctacatcggcagtatgacgccctgggtgagctgatccgagcgctgcccaaa gcctacatcatcaacgcagtgtccgtgcaggacaccatggagctactggagtgtctggga caaatccgatccctgctcattgttcagatgggtccagaagaggaaagactgatgattcag agtattggaaatattatgagcaacagggtgttctaccagcaccccaacctgatgagagct ctgggaatgcacgagactgtcatggaggttatggtgaatgtgcttggaggtggagattcc aaggagattcggtttccccgaatggtgaccaactgctgtcgtttcctgtgttatttctgt cggatcagcagacagaatcagcgctcaatgttcgatcacctcggctacctcctacagaac agtggcattgggctaggaatgcgtggctccacaccgcttgatgtagctgcagcatcttgt attgataataatgagcttgccctggctctccaagagcaagacctggagatggtggtgaag tacttggcaggttgtggcctgcagagctgccccatgctcttatcgaaaggttacccagac atcggatggaacccatgtggaggagagaagtatctggatttcctgcgctttgctgtattt gtcaatggagaaagcgtggaggagaatgctaacgtggtggtccggctgctgatcagaagg cctgagtgttttggtcctgcgctgagaggagaggggggcaacggtctgcttgctgccatt gaagaggccattaagatttcagaggatcctgcaagagacggacccactgttaagaaagac agacgctttccaatgtttggtggagaagagcagcatgaggagaaccgagtgcacttggga aatgccatcatgtccttttactcagctcttattgatctgctgggtcgctgtgctcctgag atgcatttgatccaggctggtaaaggtgaagcgttgaggatcagggccattcttaggtct cttgtgcccattgaggatctggttggtgtgataagcttgccagtccagatacctgcttta ggaaaagataacagtatcatcgagccaaagatgtctgccagttttgtgcctgatcacaaa gcaccaatggtgctgttcctcgacagagtgtatgggattgataaccaggacttcctgttg catgtactggaggtgggcttcctgcccgacatgagagcagcagcttccctggacacggct gcgttcagtaccacagagatggccctggctctgaaccgttacctttgctccgctgtgctt cctctcattactaaatgtgctcctttgtttgctggcacggaccaccgtgccatcatgatt gactccatgctccacaccatctacaggctgtcccgaggacgctctctaaccaaagctcag agagatgttattgaggaatgcctcatgtctttgtgcaggtatctgcgtccttccatgctc cagcaccttctcaggcgattggtatttgatgtgccaattctgaatgaatacgccaaaatg ccccttaagctgcttactaatcattatgagcgttgttggaagtactattgtttgcccaat ggctgggccaactttggcatatcgtcagaagaggagcttcatctcacccgtaaactcttc tggggaatttttgaatctctggcccacaagaaatttgatgcagagctgtttaaaattgca atgccctgcatatgtgcaattgctggggcaatcccacctgattatgtggatgccagctac tcctccaagacagaaaaaaaggcttctgttgatgctgaaggcaactttgaccccaaacct gtggataccacaaatactattattcctgagaaactggatggcttcatcaacagatatgca gaatacacacatgacaaatgggcttttgaaaagatccagaataactggacattcggtgaa ttgctggatgaaaatgctaagactcatcccatgctcaggccttacaaaacgttctctgaa aaggataaagaaatctaccgatggcccattaaagagtccataaaggccatgattgcttgg gagtggacactggacaaagccagagatggtgaagatgagaaaacagaaaagaagacaact cgcaagatctcacagactgcacaggccacttatgaccccagtcatggctacagtcctcag cccattgacatctcaggcatgacactgtccagagagcttcagtccatggcagaacagctg gcagagaattaccacaacacctggggacggaaaaagaaaatggagctacaatcaaaaggg ggagggacacaccctttgcttgtaccgtatgatacattgacagctaaagaaaaggcaaga gacagggagaaagcacatgaactactcaaatttctgcagcttaatggatatgctgtaacc agaggacttaaggatatggagagtgatatttcatctattgagaaacgttttgcatatggc ttccttcaaaaactgctgaaatggatggacattgcccaggagttcattgcgcatcttgag gctgttgtgagcagtggtcgtgtggaaaagtcaccacatgaacaagagatcaagttcttt gccaagattcttcttcctttgataaatcaatattttaaaaatcactgcctctacttcctc tctacaccggctaaaatcctgggcagtggtggacatgcctcaaacaaagaaaaagagatg attgcaagtatcttctgtaaaatgtctgccctggtaagacacagagtgtttctctttggt acggatgcgtctgctattgtcaattgtcttcatatccttgcacgttcacttgatgcccgg actgtgatgaaatcagggcctgaaattgtaaaggcagggctgcgttctttctatgagagt gcagctgatgatatagaaaagatggtggaaaacctcaaactcggcaaagtgtccaaaggg aatcagcctgtgaagggtgtgtcccagaatattaactacaccacaatagctctgctccct gtcctcacctccctgtttgaccacatcgctcagcaccagtttggagatgatgttatcttg gacgatttgcagatgtcctgctaccgaatcatgtgtagtatttattctcttggtactgta aaaactccacatgcagagagacatagacctgccctgggtgagtgtcttgctcatcttgct gcagccatgcctgtggcctacctggagccccatctgaatgaatacaatgcattttctgtg tacaccaccaagacgcccagggaaagagccatcctgggacttcctaaccatgtcaaggag ctgtgtttggacattccagagctagagatattgatgaaagagatcggagacctggcagaa tctggggctcgctacacagaaatgccacacgtgatagaggtcaccctgcccatgctctgt aactatctaccccgctggtgggagagaggagtggagaacttcccagaatcggagggtaag ctgtgtacagatgtcacctccgatcaactcaaccagctcctgggaagtatcatgaaaata gtggtcaacaacctgggcattgatgaagcttcatggatgaagaggcttgctgtgttctcc cagcccattgtgagccgagccaaaccagagatgctcaaatcccatttcatccccaccatg gagaaactgaagaagcgtacatctaaagtagttgccgaggaggagcacctgcgtatggag gggaagtctgagggcgacgaggaggagggaactattcgagacgaatttgcggttctgtgt agagatttgtatgctctttaccctcttctcatccgctatgtggataacaacagagcaagg tggcttacctgccgtgatccagatgctgaggagcttttccgtatggtgggagaggtcttc attttctggtccaaatctcataatttcaagcgtgaggaacaaaactttgtggtgatgaat gaaataaacaatatgtccttcctcactgctgacagcaagagcaagatgagcaagaccggg gactctgaggctggtggctcagatgtggagcgtaccaagaaaaagagacggggagatcga tattctgttcagacgtccctcattgtggcagcgctgaagaaaatgcttcccattggactc aacatgtgctctcctgcagaccaggaacttattaacctggccaagacccgctattcattg aaagacacagatgaagaggtgagagagttcttgcagaacaacctgcatctccagggcaag gtcgataacccatctatgcgctggcagatggcactgtataaggaaatggcaggaaaggca gaagatgcagatgccccagagaaagtagtgaagagagttcaggaagtctctgctgtgctt taccacattgaagtgacggagcaccctttcaagtccaaaaagatggtttggcacaaactg ctgtctaagcagaggcgtagagcagtagtggcctgtttcaggatgactcccctttacaac ctgcccaggcatagagcctctaacatgttcctggacggatacaagcggaactggatccaa acagaaggatattcctttgaagacagaatgatagatgacttgtccaaagcgatggaggaa gaggaggaggaggaagaggaaagggagacaaagcctgatcctcttcatcagcttattctt catttcagtcgcactgcacttactgagaagagtaaactggacatagattacttatacatg gcatatgctgatatcatggctaagagttgccacatgggggaagaggatgaggggggagat gaggaggtggaggggggagaagaagagatgccctttgaggaaaaagagatggaaaagcag agactcctttaccagcagtcacgtctacacaaccgtggggctgctgagatggtcctacag atgattagtgcctgcaagggtgagacaggttgtatggtctcatccaccctaaagcttggt atttctattctaaatggagggaacagtgaagtccaacagaaaatgctggactatctaaaa gacaagaaagatgttggctttttcctcagtgtccaggcactaatgcagacctgcagtgtt ttggacctgaatgcctttgagaggcagaataaagcagagggtctaggtatggtgtcagag gagggaacaaacatgaagctagaacggggtgagaaggtgatggctgatgatgagttcact tgtgacctcttccgcttcctgcagctcctctgtgagggtcacaacaatgacttccaaaac tacctcagaacacagacaggcagcaccaccaccatcaatattattatctgcacagtggat tacctgcttagactacaggagtccattagtgatttctactggtattactcaggaaaagac atcatagatgaaccaggcaagaggaacttctctaaagctatggctgtggccaaacaggtc ttcaacagcctcactgagtatatccagggtccctgcacaggaaaccagcagtctctggcc cacagcaggctttgggatgctgtggtgggcttccttcatgtgtttgcccatatgatgatg aaactggctcaggattccagtcagattggactcctaaaggagcttttggaccttcagaaa gacatggtggtcatgctgctgtctctgttggagggtaatgttgtaaatggtacaattgct cgccaaatggtggacatgctggtggaatcttctagtaatgtagaaatgatccttaaattc ttcgacatgttcctcaagctgaaggacattgtcgcgtctgatgcattccgtgactatgtg actgaccccagaggtcttatatccaagaaagacttccagaaagccatggacagtcaaaaa cagtacaccccttcagagatccagtttctgttgtcctgctcagaggcagatgagaatgag atgattaattacgaggagtttgccagccgcttccaagagccagcaaaagatattgggttt aacattgccgtgctgctcaccaacctctccgaacacgttcctcatgataccaggttacaa aacttccttgaacaggctgagagcgttcttaactatttccgcccatttttgggtcgtatt gagatcatgggtgccagcaggaagattgagagaatttactttgagatcagtgaggtgaac cgtaaacagtgggagatgcctcaagtgaaagagtccaagcggcagttcatatttgatgtg gtcaacgagggtggcgagtcagagaaaatggagctttttgtcaacttctgcgaggacacc atcttcgagatgaatattgcgtcacaaatttcagagcaggaagaggaagagaaagaagag gacgataatgaagaacctgaaggaggagatggaggaggcagcgatgaagagggtggtgga gaggagggccaaccagaatcaagctctgcctttgctgatttcatcaaaagcattatgaat tttctaggcctgttcaattttcggaatattcgcaggcagtaccgtaggctcaggaagatg actatcaaggaaattgttgtaggccttgctaccttcctctggaccatccttatgggcatc ctccatttcatctacagtgtgtgtaaaggtttcttcttgcttatctggcaaacacttttt ggaggtggtttagttgaaggggccaagaacatcacggtgacagagatactggccagcatg ccggatcccacacaggacgaggtccacggagacctacctggtgaaccgaggggtggagaa gagcaggaaatgggaggcataactgattcaatggatgcaggaggtggagaggaggaggat gaggacatccaagaaaaagatggtgggaagattcctggtattgatacacctggtggactt ggcgatatgggtgacacaactcctgtggaacctcctactccagagggcactcctttatta aagaggaaaatgcagccagaagaggcaggacctgaacaacctcctgctattgaagaacct cctcctgagcctgagaaagcagacactgagaatggtgagaaggctggtaaggaattagag gccaagcctgaaacaacaccaaaagaaccaaaaatggcgaaagccaccaaaaccaagaaa gagaaaaggtcagccaaaggagcaggatttgagctctggaacgagctggatgtgcaaaga aataaattcatgaactgtttgtctcgtaatttctacaaccttcgtttcctggctctgttc atcgcctttgccctgaattttattttactcttctacaaggtgtcagatactcctcccgat gttgaagagtttgaaggctctgggctttttgaaggctctgggctgtttgaaagctctggg gaggaggtagagggctctggtggagaagatgtaggtgatgatgatgaggaaggacccgtt tactatttcctggaagagagtaccggttacatgcagcccactctgtccttcctagccatt ctgcacaccgttattgctttcatttccatcattggatacaactgcctcaagattccactg gtcatctttaagagagagaaggaactggcgaggaagctggagtttgatggtctttacatc acagagcagccagaagatgatgacatcaagggccagtgggacagactggtgctaaacaca ccctcctttcccagcaactactgggacaaatttgttaagcgaaaggtactggataaatat ggagatatttatggacgtgagcgaattgctgagctgctgggtatggacctggcatctcta gatgtcagcaaacaacagacggacaagaaacctgaagagccagacaactctatactggca tggctcactgccattgacatcaagtaccaggtctggaaatttggagttgttttcacagac aatactttcctctacctggtatggtacactgtgatgtcactactgggacattacaacaat ttcttctttgcttgtcacctgctggacatcgcaatgaatgtcaaaaccctccgcaccatt ctttcctcagtcacacacaacggaaaacagctgatgatgacagtgggtttgctggccgtg gttgtgtacctctacactgtggtggccttcaacttcttcaggaagttctacaataagagt gaggatgaggacgagccagacatgaagtgtgacgacatgatgacgtgttatctgttccac atgtatgtgggtgtgcgggcaggtggaggtataggagatgagattgaggatccagctggt gatgaatatgagctctatcgtgtggttttcgacatcaccttctttttctttgtcatcgtc atcctgctcgccatcattcagggtttaatcattgatgcctttggtgagctgagagaccag caagaacaagtaaaagaggacatggagaccaaatgctttatatgtggcattgggagtgat tactttgatacaactccacatggttttgagactcatacgctggaggaacacaacttggcc aattacatgttcttcctgatgtacttaatcaacaaagatgaaactgagcacacagggcag gagtcgtatgtgtggaagatgtaccaagagaggtgctgggatttcttccctgctggagac tgcttccgaaaacaatatgaagatcagctaggataa

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