Myxocyprinus asiaticus (Chinese sucker): 127456501 Help Entry 127456501         CDS       T08782                                  Name (RefSeq) ryanodine receptor 1-like   KO K04961   ryanodine receptor 1 Organism masi  Myxocyprinus asiaticus (Chinese sucker) Pathway masi04020   Calcium signaling pathway masi04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:masi00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     127456501    04020 Calcium signaling pathway     127456501  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:masi01009]     127456501   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:masi04147]     127456501    04040 Ion channels [BR:masi04040]     127456501 Protein phosphatases and associated proteins [BR:masi01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      127456501 Exosome [BR:masi04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    127456501 Ion channels [BR:masi04040]  Voltage-gated cation channels   Ryanodine receptor    127456501 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 Motif Other DBs NCBI-GeneID:  127456501 NCBI-ProteinID:  XP_051580987 LinkDB All DBs Position 18:complement(17626792..17756917) Genome browser AA seq 5076 aa AA seqDB search MAEGEGGDEEIQFLRTEDQVVLQCSATVLKEQIKLCLSCEGFGNRLCFLETTSNAQNVPP DLAICAFILEQSLSVRALQEMLANTVEMMESSQGGGHRTLLYGHAILLRHYHSGMYLSCL TSSRSLTDKLAFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLH LSYASGDLMVDASFMQTLWNMNPICSGCELAEGYVTGGQVLRLFHGHMDECLAISTPDQG EEQRKIAQYEGGAVCNQARSLWRLEPLRIGWSGSHMKWGQAFRVRHITTGRYLCLDEEKG LMVLDPEKANTKLSAFCFRASKEKVEGAQKKRDVEGMGVPEIKYGESMCFVQHLSTGLWL TYAALDAKAARLGTMKRRAILHQEGHMDDALTMSRSQTEESQAARMIYSTTGLFTQFIKG LDSLSGKNKSPGPVFLPLDGVILSLQDLIHYFRPPEEELEHEEKQTKLRSLRNRQNLFQE EGMITIVLECVDRLNVYNTAAHFSEFAGEEAAESWKEIVNLLYELLASLIRGNRANCALF CDNLDWLVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVL DVLRSLCVCNGVAVRSNQNLITENLLPGRDLLLQTNIVNFVSSVRPNIFLGTCEGSTQYK KWYFEVMVDYVEAFVTAQATHLRVGWAMTEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLH LWSGHVSRQVASPNQHSLAADDVVSCCLDLSVPSISFRINGHPVQGMFENFNVDGLFFPV ISFSAGVKARFLLGGRHGDFKFLPPPGYTPCYEALLPKDRMRIEPIKEYKHDFDGVRNLL GPTQSLTHTSFTPCPVDTAQIVLPPHLERIREKLAENIHELWAVTRIEQGWTYGVFRDDN KKLHPCLVDFQSLPDAERNYNLQMSGETLKTLLALGCHVGMGDEKAEENLRKIKLPKTYV MSSGYKPAPLDLSHVKLTPNQNQLVEKLAENGHNVWARDRVRQGWTYSIVQDIMNKRNPR LVPYNLLDERTKKTNRDSVNNAVRTLIGYGYNIEPPDQESSGHGVDNARGDKVRIFRAEK QYAVTSGKWYFEFEAVTIGEMRVGWARPNVHSNVELGSDELAYVFNGNRAQRWHIGNEPF GRQWQSGDVVGCMIDLTDMNIMFTLNGEMLISDSGSEMAFKDIEIGDGFIPVCTLGLSQV GRINLGQNVSSLRYFAICGLQEGFEPFAINMKRDITMWFSKSLPQFVPVPTDHNHIEVSR VDGTVDSAPCLKITHKTFGSQNANTDMLFFRLSMPVEFDLTFKVTAGTTPLTRALTIPEE EVLEVDPDSEFEVLKKSASRKEQEEKEKEPSVPKDVQSIKENDKDTVSEKGKKKGFLFKA RKAAMISPPPPPLMPRLFEDVVPDDRDDPEIILNTTTYYYSVRIFAGQEPSGVWVGWVTP DFHMYDLNFDLSKVRTVTLTVGDDKGNIHDSIRRSNCYMVWGGEFSNSQQKFSQEDQVIG CLVDLATGLMTFTANGKEVNTFYQVEPNSKLFPAVFVLPASQNMLQLELGKLKNIMPLSA AMFHSERKNPVPQCPPRLDVEMLTPVIWSRMPNHFLKPEVRRVSERHGWMVECTEPLTMM ALHIPEENRCIDILELSERHDLLKFHYHTLMLYCAVCALGNNRVAHALCSHVDESQLFYA IENTYLPGPLRSGYYDLLISIHLESAKRNRLGTNREFIIPMSEETLSITLFPDAEAAHDL PGVGLTTCLRPKLHFCNINFVGTDPDLYTLSPIIPLQELKTQALSMLTEAVLDGSQAMRD PVGGSVEFHFVPILKLISTLLIMGIFNDDDVKHILKMIDPSVFGKKEEEAGEKEESGEKA APKEEGEEVKEKEEMAEGEEEAMDEGLGEEEEEELKALKKEGEEGEGVEKAVEEEEEEGE KVDGEKAEEEKEAEEVGEEAQEEEEEAPEEGLLQMKLPESVKLQMCTLLQYFCDCELRHR VEAILAFSNNFVQQIQLNQRERYGKLMKAFTMSAAETARRTREFRSPPQEQVFLLTNFKH SPEDEDCPVPEEVRETLQNFHNDLLNHCGVHVEEEEEAKEVDASLRGRLLSLVEKVKNIR KKNEEEDPEPEEQPKPSTLQELISHTMILWAQESFIQNPELVRLMFSLLHRQYDALGELI RALPKAYAINAVSIQDTMDMLECLGQIRSLLIVQMGPEEERLMIQSIGNIMNNKVFYQHP NLMRALGMHETVMEVMVNVLGGGGDSKEIRFPQMVTNCCRFLCYFCRISRQNQRSMFDHL SYLLQNSGIGLGMRGSTPLDVAAASCIDNNELALALQEQDLEMVVTYLAGCGLRMCPMLL SKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRRPECFGPALRGEGGA GLLAAIEEAIKISEDPARDGPTPKKDRRFMFGGEEQHEENRVHLGNAVMSFYSALIDLLG RCAPEMHLIQAGKGEALRIRAILRSLVPIEDLVGVISLPVQIPTFGKDGQIVEPKMSASF VPDHKASMVLFLDRVYGIDNQDFLLHVLEVGFLPDMRAAASLDTAAFSTTEMALALNRYL CSAVLPLLTKCAPLFAGTDHRAIMIDSMLHTIYRLSRGRALTKAQRDIIEDCLMSLVKYL RPSMLQHLLRRLVFDVPILNEYAKMPLKLLTNHYERCWKYYCLPNGWANFGVTSEEELHL SRKLFWGIFESLAHKKFDAELFKIAMPCICAIAGAIPPDYVDASYSSMTEKKASVDAEGN FDPKPVETTNTIIPERLDAFINKYAEHTHDKWAFEKIQNNWTYGEVLDENAKTHPMLRPY KTFSEKDKEIYRWPIKESIKAMLAWEWTLEKARDGETEKTEVKATRKISQTAQATYDPSQ GYSPQPVDLISMALSRELQSMAEQLAENYHNTWGRKKKMELQAKGGGTHPLLVPYDTLTA KEKTRDREKAQDLLKFLQFNGYAVTRGLKDMEQEISSIEKRFAYGFLQKLLKWMEIAQEF IAHLEAVVSSGRVEKSPHEQEIKFFAKILLPLINQYFKNHCLYFLSTPAKVLGSGGHASN KEKEMIASIFCKLAGLVRHRVSLFGTDASAVVNCLHILSRSLDARTVMKSGPEIVKAGLR SFFESAADDIEKMVENLKLGKVSTKNQVKGVSQNINYTTNALLPVLTSLFDHIAQHQFGD DVILDDLQISCYRIMCSIYSLGTVKTPHAENQRPALGECLAHLAAAMPVAFLEPNLNEFN AFSVYTTKTPRERTILGLPSQVQELCLDIPELDVLMKDIGHLAESGARYTEMPHVIEITL PMLCNYLPRWWERGPENFPEQEGCLCTDVTSEQLNQLLGSIMKIVVNNLGIDEASWMKRL AVFAQPIVSRAKPEMLKSHFIPTMEKLKKRSGKVVAEEEQLRMEGKTEVDSEEGTIRDEF AVLCRDLYALYPLLIRYVDNNRARWLTCPDPDAEDLFRMVGEVFIFWSKSHNFKREEQNF VVMNEINNMSFLTADSKSKMSKTGDGEGGGSDVERTKKKRRGDRYSVQTSLIVAALKKLL PIGLNMCSPADQELINMAKIRYSLKDTDEEVREFLQNNLHLQDKVEDPSMRWQMALYKET SGKAEDADAPEKVVKRVQEVSAVLYHLELTEHPYKSKKMVWHKLLSKQRRRAVVACFRMT PLYNIPRHRASNMFLNGYKRNWIENEGYSFEDKMIDDLSKAMEQEEEEEEETEAKPDPLH QLILHFSRTALTEKTKLEVDHLYMSYADIMAKSCHIGEEDEGGEEGGDEPSFEVRQTEME KEMEKQRLLYQQSRLHDRGAAEMVLQMISACKGETGAMVSSTLKLGISILNGGNSDVQQR MLDYLKDKKDVGFFLSLQALMQTCSVLDLNAFERQNKADGLGMVSEEGSNIKLEREEKVM ADDEFTCDLFRFLQLLCEGHNNDFQNYLRTQTGSTTTINIIICTVDYLLRLQESISDFYW YYSGKDIIDEPGKRNFSKAMTVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHV FAHMMMKLAQDSSQIGLLKELLDLQKDMVVMLLSLLEGNVVNGTIARQMVDMLVESSSNV EMILKFFDMFLKLKDIVASDAFRDYVTDPRGLISKKDFSKAMDSQKQYTPSEIQFLLSCS EADENEMINFEEFADRFQEPAKDIGFNIAVLLTNLSEHVPHDTRLQNFLEQADSVLNYFR PFLGRIEIMGASKRIERIYFEISEANRNQWEMPQVRESKRQFIFDVVNEGGESEKMELFV NFCEDTIFEMNIASQISEQEEEAVEDNDEEDEESGGGGNGEGEGEEGNGEEAPPESSSAF ADFIKSVVNFLSLFTFRNLRRRYRKIRKMTIKDMIVGLVMFLYTVLFGILHFIYSVCKGF FMLIWNTLFGGGLVEGAKKMTLTEILTNMPDPTQDEVHGDLPPEPGARKVQESGGTGEGE EGAAGGEEEEEDGEEADGGGPGFGPHGGLGDMGDTEPEEPPTPEGSPLLMRKLLAEAGGE GQGEVVEEEKIEEEAAPEPEKADAENGEKTEKEAEPEEQQDELEEKKAMAKAKKGKKEAE EGFELWNELEVQRIKFMNYLSRNFYNLRFLALFIAFALNFILLFYRVSDSPRGEEELEGS AMFEGSGVFEDSGAFEGSGVFEGSGGEAEGSGMEENGEEDDEEGFVYYFLEESTGYMQPA MAFFSIIHTIISFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYVTEQPEDDDIKGQWD RLVLNTPSFPNNYWDKFVKRKVLDKYGDIYGRERIAELLGMDLASLDVSAMTHEKKPQPD PSMFTWLTSIDIKYQIWKFGVVFTDNTFLYLVWYMVMSVLGHFNNFFFACHLLDIAMGVK TLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNMSEDEDEPDMKCDDMMT CYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFG ELRDQQEQVREDMETKCFICGIGSDYFDSTPHGFETHTMEEHNLANYMFFLMYLINKDET EHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 15231 nt NT seq  +upstreamnt  +downstreamnt atggcagagggagaggggggagatgaggagatacagttcttgcggacggaagaccaagtt gtgctccagtgcagtgcgactgttctgaaggagcagatcaaactatgcctttcctgtgaa gggttcgggaaccgtctgtgctttcttgagacaacgtcaaatgcccagaatgtgccgcct gatctggcaatctgtgcctttatactggagcagtcgctctcggtacgagccctgcaggag atgctggcaaacaccgtggagatgatggagtcatctcagggagggggtcaccgaacgctg ctttatggtcatgccatcctcctgagacactaccactctggcatgtatttgagctgcctg acatcatcccggtcacttacagacaagctggcttttgatgtgggcctgcaggaggattca acaggggaagcatgctggtggaccatccatcctgcatccaagcagaggtcagagggtgag aaggtcagagtaggagatgacctgatcctggttagcgtatcatcagagagatacctgcat ctatcctatgccagtggtgacttgatggtagatgcctccttcatgcagactttatggaac atgaatccgatctgctctggctgtgagctggcagaggggtacgtaaccggaggtcaagtc ttaaggctgttccatggtcacatggatgagtgtctggccatctcaacacctgatcaggga gaggaacagcgaaagattgcacagtatgaaggaggggcggtatgtaatcaggcccgttca ttgtggagacttgagcctctgagaatcggttggagtggtagccatatgaagtggggccag gccttccgcgtacgtcacatcacgacgggtcgatacctgtgtctggacgaggaaaaggga ctgatggttctcgacccagagaaagccaacacaaaactgtctgctttctgcttccgtgca tcaaaggagaaggtggagggggctcagaagaagcgagatgtggaaggaatgggtgttcct gagatcaagtatggcgagtccatgtgctttgttcagcatctctctacagggctgtggctc acatacgctgctctagacgccaaagcagctcgcctgggaaccatgaagagaagggccata ttgcatcaagagggtcatatggatgatgcactaactatgtctcgctcccagacagaagaa tctcaggctgctcgtatgatctacagcaccactggcctttttacacagttcatcaaaggc ctcgactctctgagtggtaagaacaaatcccccggtccagtgttcctgccgctggatgga gtgattctgtccttgcaggatctgatccactatttccgacctccagaggaggagctagaa cacgaggagaagcagaccaagctgcgctctctacgcaaccgacagaacctcttccaagaa gaggggatgatcacaatcgtgcttgagtgtgtggatcgtctgaatgtctacaacactgct gcacacttttctgagtttgccggggaggaagcggccgagtcttggaaagagattgtcaac ctgctctatgaactgcttgcatctctgatcagaggaaaccgtgctaactgtgctctgttc tgcgataatctggactggctggtcagtaaactggatcgtctagaagcttcttcaggcatt ctggaggtgctgtactgtgttttgattgaaagtcctgaagtcttgaacatcatccaggag aaccacatcaagtctatcatttctctcttggacaaacacggtcgaaaccataaggtttta gatgtgcttcgctctctctgtgtgtgtaatggtgtggctgtgaggtccaaccaaaaccta attacagaaaatttgcttccgggtcgtgaccttctgctgcagactaacattgttaacttt gtatcaagtgtgagacccaatatcttcttgggcacatgtgaaggttctacacagtacaaa aagtggtactttgaggtgatggtagactatgtggaggcgtttgtgacagcccaggctaca catctgcgtgtgggctgggcaatgactgagggctacagtccttacccaggaggaggagaa ggttggggtggcaatggtgtgggtgatgatctctactcttacggctttgatggcctccac ttgtggtcaggtcatgtgtcacgtcaggtggcttcacccaaccagcacagcctggcagca gatgatgttgtgagctgctgtctggatctgagcgtgcccagtatctccttccgcatcaat ggtcatccagtccaggggatgtttgagaacttcaacgttgatggccttttctttcctgtc attagcttctctgctggagtaaaagcacgtttccttttgggtggtcgtcacggtgatttt aagtttctaccccctcccggctacacaccatgttatgaagctcttctccccaaagacaga atgcgcattgagcccattaaggagtataaacatgactttgatggtgtcagaaacctgctg ggtcccacacagtccctcacgcacacctcatttactccctgccctgtggacactgcccag attgtgctacctcctcatttggagcgcatcagagagaagcttgcagaaaacatccacgag ctttgggccgtgacccgtattgagcaaggttggacttatggagtgtttagggatgataat aagaaactgcacccatgcctggtggacttccagagtcttccagatgccgagaggaactat aaccttcagatgtctggagagactttaaaaacactcttagctcttggctgccatgtagga atgggagatgagaaagcagaagagaatctgaggaagatcaaactacccaaaacatatgtg atgagcagcgggtacaagcctgctcctctggatctcagtcatgtcaaactgacgcccaat caaaaccagctggtggagaagctggcagaaaatgggcacaatgtgtgggcacgagacaga gtgagacagggttggacctacagtattgtgcaggacatcatgaataagcgtaaccctcgt ctggtgccatacaacctgctggatgagagaaccaaaaagaccaacagagacagtgtgaac aatgcagtacggactctgattggttatggatacaacatcgagcccccagatcaggagagc agtgggcatggtgttgataatgcacgtggagataaagtgcgtatcttcagggcagagaag cagtatgctgttacctcaggaaaatggtactttgagtttgaggctgtaaccataggcgag atgagagtgggctgggctcgaccaaatgtccactctaatgttgagcttggttccgatgag ctggcttatgtctttaatggaaacagggctcagcgatggcacattggtaatgagccattt gggcgtcagtggcagtctggtgatgtggtgggctgcatgatagacctcactgatatgaac ataatgttcactcttaatggagagatgctgatcagcgattctggctctgaaatggccttc aaagatattgagattggagacggttttattccagtctgcacattgggtctgtctcaggtg ggtcgtattaacctgggccagaatgttagcagtctgcgctactttgccatctgtggactt caagaaggctttgagccattcgccatcaacatgaagagagacatcacaatgtggttcagt aagagcctgccccagtttgttccagtgcctaccgaccacaaccacattgaggtgtctcgt gtggatggaactgtggacagtgccccctgtctgaaaataacacacaagacatttggatcc caaaacgctaacacagacatgctattcttcagactgagcatgcctgtggagttcgacctg accttcaaggtgaccgcaggcaccactcctcttacacgtgccctcaccatccctgaggaa gaggtgctggaggtggaccctgactctgagtttgaggtgctgaagaaatcagccagtcgc aaagagcaggaggagaaggaaaaggagccatcagtgcccaaagatgtgcagagcataaag gagaatgacaaagacactgtatccgagaaaggaaagaagaaaggtttcctgtttaaggct agaaaggcggccatgatctcccctccccctcctcctcttatgccccgtttgtttgaagat gtggtgccagatgatcgtgatgacccagagatcatcctcaatacgactacatactattac tctgtgcgtatctttgccgggcaagaacctagcggggtgtgggtgggctgggtcaccccg gacttccacatgtatgacctcaactttgacctgtctaaggtccgtactgtcactttaacc gttggagacgacaagggcaacatacacgacagtataaggaggagtaactgttacatggtg tggggaggagagtttagcaactcccaacagaagttcagccaggaggatcaagtgataggt tgcttggttgacctagcaacaggtctcatgactttcacagccaatgggaaggaggtcaac actttctatcaggtggagcccaactcaaaactcttcccagctgtgtttgtgctgccggcc agccagaacatgctgcaactggagctgggaaaactcaagaatatcatgcctctttcagct gccatgttccatagtgagcgtaagaacccagtgcctcagtgtccacctcggctggatgtg gagatgctgaccccagtgatctggagcaggatgcccaaccatttcctgaaaccagaagtg aggcgggtcagtgagaggcatggctggatggtggaatgtactgagcctctcactatgatg gctctgcatatacctgaagagaacaggtgtattgatatcctagaactgtctgagcggcat gacctgctgaaatttcactatcacactctgatgctttactgtgccgtgtgtgcattgggc aacaatcgtgtggcccatgctctttgcagtcatgtggacgaatcacagctcttctacgct attgagaacacctacctgcctggcccactccgcagtggctactacgaccttctcatcagt atccacctagagtcagctaaacgcaaccgcttgggaaccaaccgggagttcatcataccc atgtcggaggagaccctcagtattacacttttcccggatgcagaggcagctcatgacctg cctggagtgggcctcactacctgcctcagacccaagctacacttctgcaacatcaacttt gtgggcactgacccagacctgtacacccttagccccattatcccactgcaggagcttaag acccaagctctgagcatgctgactgaagctgtgttggatggcagtcaggctatgcgcgac cctgtagggggcagcgttgagttccacttcgttcccatcctcaaactaatcagcaccctc ctcattatgggcattttcaatgacgatgacgtcaagcacatcctcaagatgattgaccct agtgtgttcggaaagaaagaggaggaggcaggagagaaagaggaatcaggagagaaagct gctcccaaggaggagggagaggaggtgaaagagaaagaagagatggctgaaggagaggag gaggcaatggatgaaggactaggggaggaggaggaggaggagctgaaagccctgaagaag gaaggagaggaaggagaaggggtcgagaaggcagtggaggaggaggaggaggaaggagag aaggtggatggagaaaaagcagaggaagagaaggaggcagaagaagtaggagaggaagcc caagaggaggaagaggaagcaccggaggaggggctgctccaaatgaagcttccagagtct gtaaaactgcagatgtgtacgcttctacagtatttctgtgactgtgagctcagacacaga gttgaggctattttggcgttctccaataactttgtacagcagatccaattaaaccagcgt gaaagatatggcaagctaatgaaagcatttacaatgtccgccgctgaaactgctcgcagg acccgagagttccgctcccctcctcaggaacaggttttcctgttgacaaacttcaagcac agcccagaggacgaggactgcccagtgcctgaagaagtgcgtgaaaccctccagaatttc cataatgacctcctgaatcactgcggtgtccatgttgaagaagaagaggaggcgaaagaa gtggatgcatctctcagaggaagactgctcagtcttgtggagaaggtcaagaacatcagg aagaaaaatgaggaagaggatccagaaccagaggaacaacccaaacctagcacattacag gagttgatatcccacactatgattctctgggctcaggaatccttcattcagaaccctgag ctggtgcggctgatgttcagtcttctccaccgccagtatgatgctctgggagagttgatc cgcgcactgcctaaggcctatgccattaacgctgtgtctatacaggacaccatggacatg ctagagtgcctggggcagatccgctccctgctcatcgtccagatgggcccagaagaggag aggcttatgatccagagcattgggaacattatgaacaacaaagtgttttaccagcaccct aatctgatgcgagccctgggcatgcatgagacagtcatggaggtcatggtaaacgtgcta ggaggtggtggagactctaaggaaattcgattcccgcaaatggtgaccaattgctgtcgc ttcctgtgctacttctgtaggatcagccgtcagaaccagcgatccatgtttgaccatctc tcatacctgctgcagaacagtggcattggactagggatgcgtggatccacacctcttgat gttgctgctgcatcctgcattgacaacaatgagctggccctggctctacaagaacaagac ctcgagatggtagtgacatacctggctggctgcggcctgcgaatgtgtcccatgcttctt tctaaaggctaccctgacataggatggaatccatgtggaggagagagatacttggacttc ctgcgctttgctgtgtttgtcaatggtgagagcgtagaggagaacgccaatgtggttgtt cgtctgttgattcgtcggcccgagtgcttcggccccgccctgaggggagagggtggtgca ggtctgttagctgccattgaggaggctattaagatctctgaagaccctgccagagatggg ccgactcctaaaaaggacagacgtttcatgtttggaggggaggagcaacatgaggagaac agagtgcatcttgggaatgctgtcatgtcattttactcagcccttatagacttgttgggt cgctgtgcccctgagatgcatttgatccaggcaggtaaaggtgaagctttgagaatcaga gccatcttgaggtctctggtgcccattgaagatctagtgggagtcatcagcttacctgtt cagatccccacctttggcaaagatggtcagatcgttgagccaaaaatgtcagcgagtttc gtgccagaccacaaagcctccatggtgcttttcctggacagagtgtacggcattgataac caggacttcctgttgcatgtgctggaggtgggcttcctgcccgatatgagagctgcagcc tctctggatacggcagcgttcagcaccacagagatggcacttgctctgaaccgttacctg tgctcagctgtgctgcctctgctcactaagtgtgccccactgttcgctggcacagaccac cgtgccattatgatcgactctatgctgcacactatctataggctgtcccgtggccgtgct cttaccaaagctcaaagagatatcattgaggactgcctcatgtctcttgtcaaatatttg cgaccatccatgttgcagcatctgttgaggaggctggtgttcgatgtgccaatcctaaat gagtatgctaagatgcccctcaagttgctgaccaatcactatgagcgttgctggaagtat tattgtctgcctaatggatgggcaaactttggagtcacatcagaagaggagctgcatctc tctcggaaactcttctggggcatctttgagtccctcgcacacaagaaatttgatgccgag ctgtttaagatcgccatgccctgtatatgtgccattgcgggtgccatccctccagactat gtagatgctagctattcatccatgactgagaagaaagcatctgtagatgctgagggcaac tttgatcccaaaccagtggagacaaccaacaccatcatccctgagaggctggatgccttc attaacaaatatgctgagcacacgcatgataagtgggcctttgagaagatccaaaacaac tggacatatggagaggttctagatgagaatgccaaaacccatcccatgttgcggccatac aagactttctcagagaaggataaggagatctatcgctggcccattaaagagtccatcaag gccatgttggcttgggaatggactctggagaaagccagagatggagagactgagaaaaca gaggtgaaggccaccaggaagatctcccagactgctcaggccacctatgaccccagccag ggatactctccccagccagtagaccttataagcatggccttgtccagagagctacagtcc atggcagagcagctcgctgagaattaccacaacacatggggccgcaaaaagaagatggaa ctgcaagccaagggtggtggtacccaccctttgctggtaccatatgacacattgacagcc aaggagaagacaagggacagagagaaagcccaagacctgctcaaattcctccagttcaac ggatatgctgttaccagaggtttgaaggacatggagcaggaaatttcctccattgagaag cgctttgcttatgggttcctacagaagctgttgaagtggatggagattgcacaggagttt attgctcatcttgaggccgttgtgagcagtggaagagttgagaaatcccctcacgaacag gagattaaattctttgccaagattctgcttccattgataaaccaatactttaagaatcac tgcctgtatttcctgtccacacctgctaaagttctaggcagtggtggccacgcatccaac aaggagaaagagatgattgctagtatcttctgtaagttggccggtctggtgagacacagg gtttccctctttggcactgatgcctcagcagtggtcaactgtcttcatatcttgtcccgc tcactggatgccaggactgtgatgaaatctgggcctgagattgtgaaggctggtctgcgc tctttctttgagagtgctgccgatgatattgagaagatggttgagaacctcaaattgggg aaggtgtccaccaaaaaccaggtgaaaggtgtatctcagaatataaactacaccaccaat gctctgctgccagtgctcacctctctgtttgaccacatcgcccagcatcagtttggagat gatgtcatcttggatgatctgcagatatcctgttaccgtatcatgtgcagcatctactcc ctgggcactgtaaagacccctcatgctgagaaccaaagacctgctctaggagagtgtctg gctcatctggccgctgccatgcctgttgctttcctggagcccaacctcaatgaattcaat gcattctctgtgtacactaccaaaaccccacgagagagaacaatcctgggtctgcccagt caagtgcaggagctttgtctagatatccctgagctggacgtgttgatgaaggatatcgga catctggcagaatctggggcccgttacacagagatgccacatgtaattgagatcaccctg cccatgctgtgtaactatctgccccgctggtgggagaggggaccagagaacttcccagag caggagggttgtctttgcactgatgtcacctctgaacaactaaatcaactgctgggcagc attatgaagattgtcgtcaataacctgggcattgatgaagcttcctggatgaagagactg gcagtatttgctcagcccatcgtgagcagagcaaagccagagatgctcaagtcccacttt atacccaccatggagaagctaaagaagcgcagtggaaaggtggtggctgaggaggagcag ctgcgtatggaggggaagacggaggtggacagtgaggagggaaccattcgcgatgaattt gctgtgctctgcagggatctgtacgctctttacccgctgctcatcagatatgtggacaac aacagggcgagatggttgacctgtcctgaccctgatgctgaggacctcttcaggatggtt ggagaggtcttcattttctggtccaaatctcacaacttcaagcgtgaggagcagaacttt gtggtgatgaatgagattaacaacatgtccttcctcactgctgacagcaaaagcaagatg agcaagacaggggacggagagggtggaggctcagatgttgagcggaccaagaagaagcgg cgtggggaccgttactctgtgcagacctctttgattgtagcggccctgaagaaactactc cccattggtctcaacatgtgctctcctgcagaccaagagctcataaacatggccaagatc cgctactcactgaaagacacagatgaggaagtgagggagtttctacagaataaccttcat ctacaggacaaggtggaggacccttccatgcgctggcagatggctctgtataaggagacc tcaggcaaagctgaagatgccgatgcaccagagaaggttgtgaagagagtccaggaagtt tctgctgttctctaccaccttgagctgactgagcacccttacaagtctaagaagatggtt tggcacaagcttctgtccaagcagcgtcgtagggcggtggtggcctgcttcagaatgaca ccactgtacaacattccaaggcaccgggcatctaacatgttccttaatggatacaagcgc aactggattgaaaatgagggctactcgtttgaagacaaaatgatagatgacttatctaaa gcgatggagcaggaagaggaagaagaggaagaaactgaagcaaaaccagacccccttcat cagctcatccttcatttcagccgcaccgctctcaccgagaaaactaaacttgaagtggat catctatacatgtcatatgctgatattatggcaaaaagctgccacattggtgaggaggac gaagggggagaggaggggggcgacgaaccatcctttgaggtgcgacagacagagatggag aaggagatggaaaaacagaggcttctgtaccaacagtctcgcctacatgatcgcggagca gctgagatggtgctacagatgattagtgcctgcaaaggtgaaacaggagcaatggtgtcc tctactctcaaacttggcatctccatcctcaatggtggcaacagtgatgttcaacagaga atgttagactacttgaaggacaagaaagatgtcggcttcttcctcagcttacaggctctt atgcaaacctgcagtgttctggacctgaatgcgtttgagagacagaataaggcggatggg cttgggatggtgtcagaggagggctcgaacatcaagctagaacgtgaggagaaagtgatg gcggatgatgaattcacttgtgacctcttccgcttcctgcagctgctctgtgagggccac aacaatgatttccagaactatctgcgcacacagacaggcagcacaaccacaatcaacatc atcatctgcactgttgactatctgctcagactgcaggagtctatcagtgacttctactgg tattactctgggaaggatattattgatgaaccaggcaagaggaacttctctaaagcaatg acagttgctaaacaggtcttcaacagtctgacagagtatattcagggtccttgcactggt aatcaacagtctctggctcacagcagattgtgggatgctgtggtgggcttcttacacgtg tttgcacacatgatgatgaagctagcacaggactcgagtcaaattggtctgttgaaggag ctcctggatctacagaaggacatggtagtcatgctcctctctctactggagggtaatgtt gtgaatggcacaatcgctcgccagatggttgacatgctggttgagtcatccagcaacgtg gagatgattctcaagttcttcgacatgttcctcaaattgaaggatattgtggcgtcagat gccttccgtgactatgtgacagaccctcgtggcctcatctccaagaaggacttctccaag gctatggacagtcagaagcagtacacaccatctgagatccagttcctgctgtcctgctcc gaagcagacgagaatgagatgataaactttgaggagtttgctgaccgcttccaagagcca gccaaagacatcggcttcaacatcgctgtgctgcttacaaacctctctgagcatgtccct cacgacactcgcctacagaactttttggagcaagctgacagtgtgctgaactacttccgc cccttcctgggccgtatcgaaatcatgggtgccagcaagaggattgagcgcatctatttt gagatcagcgaggccaatcgcaaccagtgggagatgcctcaggtcagagagtcaaaacgg cagttcatctttgatgttgtcaacgaaggtggggaatctgagaagatggagctctttgtg aacttctgcgaggacaccatttttgagatgaacatcgcctcacagatctcagagcaggaa gaggaagctgtggaagacaatgatgaggaagatgaggagagcggtggtggaggaaatgga gaaggagaaggagaggaaggcaatggagaagaagcaccacctgaatccagttcagcattt gctgacttcatcaagagtgtcgtgaacttcctaagccttttcactttccgtaatctcagg cgccgttaccgtaaaatcaggaaaatgaccataaaggacatgattgttggcttggtgatg ttcctctataccgtcctttttggcattctgcatttcatctacagcgtgtgcaaaggcttc ttcatgctaatctggaacaccctcttcggaggcggtctggtagagggagcaaagaagatg acgttgacagagattttgactaacatgcccgacccaactcaggatgaggtgcacggtgac cttccccctgagcctggagcaagaaaagttcaagaatcaggtggaactggagagggagag gagggagcagctggaggagaggaagaagaagaagatggagaagaggctgatggtggaggg cctggttttggtccacatggtggacttggggacatgggagatactgagccagaggagcca ccaactcctgaaggcagtccactgctgatgaggaaactgttggctgaagcaggaggagaa ggacaaggagaggtggtagaagaggagaaaatagaggaagaagcagccccagaaccagaa aaagcagatgctgaaaatggagagaagactgagaaggaggcagagccagaggaacaacaa gatgagctagaggagaaaaaggcaatggcaaaagcaaagaaaggcaagaaagaggcagaa gagggctttgaactctggaatgaacttgaagtgcaaagaatcaaattcatgaattacctt tctcgcaatttctacaacctgcgcttcctggctctgttcatcgcctttgccctgaacttc attctgctcttctacagggtgtctgacagcccccgtggtgaggaggagcttgagggatca gctatgtttgagggttctggtgtgtttgaggactctggtgcatttgaaggctctggtgta tttgaaggctctggtggagaggctgaaggttctggaatggaggagaatggagaggaagat gatgaagaagggtttgtctattacttcctggaagagagcactggatatatgcagcctgca atggccttcttttccattatacacaccataatttccttcctgtgtatcatcggctacaac tgtctgaaggttcctttggtcatcttcaagagagagaaggagctggcccgtaaactggag tttgatggtctgtatgtaactgagcagccagaggatgatgacatcaagggccagtgggac agacttgtcctcaatacaccgagtttccccaacaactactgggacaaatttgtgaagaga aaggtgctagacaagtatggtgatatctacggtagagagagaatcgctgaactgctggga atggacctagcctctctagacgtcagtgctatgacacacgagaagaaacctcagcctgat ccctcaatgttcacttggttgacgtctattgatatcaagtaccagatctggaaatttggt gttgtgttcactgataataccttcctgtacctggtttggtatatggtcatgtccgtgctt ggtcacttcaacaatttcttttttgcctgtcatctgctggacatcgctatgggtgtcaaa accctgcgcaccatcctgtcctctgtaacccacaatggcaaacagctggtgatgactgtg ggtctgctggctgtagtggtctacctctacaccgtggtagccttcaacttcttccgaaag ttctacaacatgagtgaggatgaagatgaaccggatatgaagtgtgacgacatgatgact tgttatctattccatatgtacgtgggtgtgagggccggtggtggtataggagatgagatc gaggatccggctggtgatgagtatgagctttatcgtgtggtctttgatatcaccttcttc ttttttgtcatcgtcatcctgctggccatcattcagggtctgatcattgatgcctttggt gagctgagagatcagcaggagcaggtccgagaagacatggagactaagtgcttcatctgt ggaattggaagtgactactttgactcgactccacatggctttgagacgcatacaatggag gagcacaatttagccaactacatgttcttcctgatgtatttaatcaataaagatgaaact gagcacacaggacaggagtcatatgtatggaaaatgtaccaggagcgatgctgggacttc ttcccagctggtgactgtttcaggaagcaatatgaggatcaacttggctaa

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