Micromonospora aurantiaca: Micau_4703
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Entry
Micau_4703 CDS
T01296
Name
(GenBank) 2-oxo-acid dehydrogenase E1 subunit, homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mau
Micromonospora aurantiaca
Pathway
mau00010
Glycolysis / Gluconeogenesis
mau00020
Citrate cycle (TCA cycle)
mau00620
Pyruvate metabolism
mau00785
Lipoic acid metabolism
mau01100
Metabolic pathways
mau01110
Biosynthesis of secondary metabolites
mau01120
Microbial metabolism in diverse environments
mau01200
Carbon metabolism
mau01210
2-Oxocarboxylic acid metabolism
Module
mau_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mau00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Micau_4703
00020 Citrate cycle (TCA cycle)
Micau_4703
00620 Pyruvate metabolism
Micau_4703
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Micau_4703
Enzymes [BR:
mau01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Micau_4703
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ADL48213
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Position
5316999..5319743
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AA seq
914 aa
AA seq
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MATERKRPVITAGLPSQLPDIDPEETSEWVESLDGVIDERGTKRARYVMLRLLERARERQ
VGVPSLTTTDYINTIPPEREPWFPGDEHVERRLRAYIRWNAAMLVHRAQRPEIGVGGHIS
TFASSASLYEVGFNHFFRGKNHPGGGDQIFYQGHASPGMYARAFLEGRLSESQLDGFRQE
LSHPGGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNRYLHHRGIKDTSQQHVWA
FLGDGEMDEVESLGAIGVAAREELDNLTFVINCNLQRLDGPVRGNGKVMQELEAFFRGAG
WNVIKVVWGREWDPLLAADTDGALVNLMNTTPDGDYQTYKAESGSYVREHFFGRDPRTRK
MVEHLSDDEIWNLKRGGHDYRKLYAAYKAAMEHTGQPTVILAKTIKGWTLGSHFEGRNAT
HQMKKLTLEDLKLFRDRLYLDIPDKQLEENPYLPPYYTPGEKSDEIAYLKDRRQQLGGYL
PTRSTARKTLAIPGTERFSDVKRGSGKQKVATTMAFVRLLKDIMKDKEFGKRWVPIIPDE
ARTFGMDSLFPTQKIYSPHGQRYTSVDRELFLSYKESTTGQILHEGINEAGSVASFTAAG
TAYATHGEPMIPLYIFYSMFGFQRTGDGFWAAADQMARGFVLGATAGRTTLNGEGLQHED
GHSLLLAATNPAVVSYDAAFAFELAHIVENGLHRMYGEAQENIFYYLTIYNEPIFQPAEP
EGVDVEGILKGIHRYSPAPQVGDDAPKANILASGTGMQWALKAQQLLAEDWGVSADVWSV
TSWTELRRDAVECEEHNLLNPGEEPRVPYIARKLADADGPKVAVSDWMRAVPDLIARWVP
GDYTSLGTDGFGMSDTRHALRRHFHVDAESVAVATLRQLALRGVVPAHVPADAARKYALD
DVNAAPVGETGGDS
NT seq
2745 nt
NT seq
+upstream
nt +downstream
nt
gtggctacggaacgcaagcgcccggtgatcaccgctggtctgccgagccagcttccggac
atcgaccctgaagagaccagcgaatgggtcgagtcactcgacggtgtcatcgacgagcgc
gggacaaagcgagcccggtacgtcatgctgcgcctgctggagcgggcccgcgagcggcag
gtcggggtgccgtcactgaccaccaccgactacatcaacacgatcccgccggagcgcgaa
ccgtggttcccgggtgacgagcacgtcgagcggcggctgcgggcgtacatcaggtggaac
gccgcgatgctggtgcaccgggcgcagcgcccggagatcggcgtcggtgggcacatctcc
acgttcgccagctcggcgtccctctacgaggtgggcttcaaccacttcttccggggcaag
aaccacccgggcggcggtgaccagatcttctaccagggtcacgcctcccccggcatgtac
gcgcgggcgttcctggagggccggctcagcgagagccagctcgacggcttccggcaggag
ctgtcgcaccccggcggcgggctcccgtcgtacccgcacccgcggctgatgccggacttc
tgggagttccccaccgtctccatgggcctcggcccgctgaacgcgatctaccaggcgcgg
ttcaaccgctacctgcaccaccgcggcatcaaggacacctcccagcagcacgtctgggcg
ttcctcggcgacggtgagatggacgaggtcgagtcgctcggcgcgatcggcgtggccgcc
cgcgaggagctggacaacctcaccttcgtgatcaactgcaacctccagcgcctggacgga
ccggtccgcggcaacggcaaggtcatgcaggagctggaggcgttcttccggggcgccggc
tggaacgtcatcaaggtggtctggggccgcgagtgggatccgctgctcgccgcggacacc
gacggcgcgctggtcaacctgatgaacaccacgcccgacggtgactaccagacctacaag
gcggagtccggttcgtacgtgcgggagcacttcttcggccgcgacccgcggacccgcaag
atggtcgagcacctgtccgacgacgagatctggaacctcaagcggggtggccacgactac
cgcaagctctacgcggcctacaaggcggcgatggagcacaccggccagccgacggtgatc
ctcgccaagacgatcaagggctggacgctcggctcgcacttcgagggccgcaacgccacc
caccagatgaagaagctgacgctggaggacctgaagctcttccgcgaccgcctctacctg
gacatcccggacaagcagctggaggagaacccgtacctcccgccgtactacaccccgggc
gagaagtccgacgagatcgcgtacctgaaggaccggcgtcagcagctcggcggctacctg
cccacgcgcagcaccgcgcgcaagacgctggccatcccgggcaccgagcggttctccgac
gtcaagcgcgggtcgggcaagcagaaggtcgccaccacgatggcgttcgtccgcctgctc
aaggacatcatgaaggacaaggagttcggcaagcgctgggtgccgatcatcccggacgag
gcccgtaccttcggtatggactcgctgttcccgacccagaagatctactcgccgcacggc
cagcgctacacctcggtggaccgagagctgttcctgtcctacaaggagtcgaccaccggc
cagatcctgcacgaggggatcaacgaggccggttcggtggcctcgttcacggccgcgggc
acggcgtacgccacccacggcgagccgatgatcccgctgtacatcttctactcgatgttc
ggcttccagcgcacgggcgacgggttctgggcggcggcggaccagatggcgcggggcttc
gtgctcggcgcgacagccggccggaccacgctcaacggtgagggcctccagcacgaggac
ggccactcgctgctgctcgccgccaccaacccggcggtggtctcctacgacgcggcgttc
gccttcgagctggcgcacatcgtggagaacggcctgcaccggatgtacggcgaggcgcag
gagaacatcttctactacctcaccatctacaacgagccgatcttccagccggccgagccg
gagggcgtggacgtcgagggcatcctcaagggcatccaccgctactcccccgcgccgcag
gtcggtgacgacgcgccgaaggcgaacatcctcgcgtccggcaccggtatgcagtgggcg
ctcaaggcccagcagctgctcgccgaggactggggcgtgtccgccgacgtgtggtcggtg
acgtcctggaccgagctgcgccgcgacgcggtggagtgcgaggagcacaacctgctcaac
ccgggcgaggagccgcgcgtgccgtacatcgcgcggaagctggccgacgccgacgggccg
aaggtcgctgtgagcgactggatgcgcgcggtgccggacctgatcgcgcgctgggtgccc
ggggactacacctcgctcggcaccgacggcttcggcatgtcggacacccggcacgcgctg
cgccgccacttccacgtggacgccgagtcggtggcggtcgcgacgctgcgccagctcgcg
ctgcgcggcgtggtgccggcgcacgtgccggccgacgcggcccgcaagtacgcgctggac
gacgtcaacgccgccccggtcggcgagaccggcggcgacagctga
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