Micromonospora aurantiaca: Micau_5222
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Entry
Micau_5222 CDS
T01296
Name
(GenBank) 2-oxoglutarate dehydrogenase, E1 subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mau
Micromonospora aurantiaca
Pathway
mau00020
Citrate cycle (TCA cycle)
mau00630
Glyoxylate and dicarboxylate metabolism
mau00785
Lipoic acid metabolism
mau01100
Metabolic pathways
mau01110
Biosynthesis of secondary metabolites
mau01120
Microbial metabolism in diverse environments
mau01200
Carbon metabolism
mau01210
2-Oxocarboxylic acid metabolism
Module
mau_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mau_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mau00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
Micau_5222
00630 Glyoxylate and dicarboxylate metabolism
Micau_5222
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Micau_5222
Enzymes [BR:
mau01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
Micau_5222
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
Micau_5222
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
Micau_5222
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
Micau_5222
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
SHOCT-like_DUF2089-C
Motif
Other DBs
NCBI-ProteinID:
ADL48728
LinkDB
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Position
5872743..5876486
Genome browser
AA seq
1247 aa
AA seq
DB search
MSTQQTSQENPLAGFGPNEWIVEEMYQRYLADPSSVDSAWHDFFADYRPAPGAATPRPDG
QAKPAAKPEPAEQQEAVATVTAQPAKTEPKAAPKATPAPAKPAAKPAAKAPEPAKKSAPA
KPAAKAPTASAAGTTPLRGVAAKIVQNMDASLAVPTATSVRAVPAKLLVDNRIVINNHLT
RGRGGKVSFTHLIGYALVRAVVEHPEMNNSFAEVDGKPAMVRPEHVNLGIAIDLVKPDGS
RNLVVPSIKGCEQMDFRQFWQAYEDVVRRARRNELTMEDYSGTTISLTNPGGIGTVHSIP
RLMQGQSAIIGVGAMEYPAPYQGMSEATLAENAVSKVITLTSTYDHRIIQGAQSGEFLKV
MHELLLGERGFYDDIFTSLRIPYEPVRWMRDVAVDSEGQINKTARVHELIHAYRVRGHLM
ADTDPLEFKIRKHPDLDVLQHGLTLWDLDRVFPVNGFAGQQRMKLRSILGVLRDSYCRRV
GIEYMHIQDPEERRWIQERVERKYEKPSSDEQKHVLNRLNAAEAFETFLQTKYVGQKRFS
LEGGESLIPLLGEVLECSAEAGLDEVVIGMAHRGRLNVLANIVGKPYEKIFSEFEGHLDP
RSTQGSGDVKYHLGQNGKFTTPDGEHAVKVSVVANPSHLEAVDPVLEGIVRAKQDRIDLK
LEGYTVLPLAVHGDAAFAGQGVVAETLNLSQLRGYRTGGTVHVVVNNQVGFTTAPEYSRS
SLYSTDVARMIQAPIFHVNGDDPEAVVRVARLAFEYRQAFNKDVVIDMVCYRRRGHNEGD
DPSMSNPEMYKIIDSKRSVRKLYTEELIGRGDITVEDAEELLRDYQGQLERVFKATRDAA
TTPRQLSRPAREEEPEPQVDTATDAAVVKAIGEAHVNLPEGFTPHKRIQQLLERRRKMSV
EGGIDWGFAEIIAFGTLLHDGVTVRLAGQDSRRGTFVQRHASVVDAKTGEDYLPLKSLTA
DGERSRFFVHDSLLSEYAAMGFEYGYSVENINALVAWEAQFGDFVNGAQSVIDEFISSGE
VKWGQRSAVTLLLPHGHEGQGPDHTSGRPERFLQLCAEDNMRVAIPTTPANYFHLLRRQA
LSPKRKPLVVFTPKSLLRHKLCVSPVEDFTTGTFQPVLADTAAPAPEQVKRVLLCSGKVY
YDLFQARQERGVTDTAILRMEQLYPLPVEEVRAALAQYPNAEDFAWVQEEPANQGAWSFV
ALNLLEHLPEVRLRRISRPAAAAPAVGSAKMHEVEQNALIEAALPRP
NT seq
3744 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgacccagcagacttcgcaggagaacccactggcgggtttcggcccgaacgagtgg
atcgtcgaggagatgtaccagcgttacctcgccgacccctcgagcgtcgattcggcctgg
cacgacttcttcgccgactaccggccggccccgggcgccgccacaccgcgcccggacggg
caggccaagccggccgcgaagccggagccggccgagcagcaggaggcggtggcgaccgtc
accgcgcagcccgccaagaccgagccgaaggccgcccccaaggccacgcccgctccggcc
aagcccgccgccaagccggcggcgaaggcgcccgagccggccaagaagtccgccccggcc
aagccggccgccaaggcgccgaccgcgagcgccgcgggcaccacgccgctgcgcggcgtc
gccgccaagatcgtgcagaacatggacgcgtcgctcgccgtcccgaccgccacgagcgtg
cgcgccgtcccggccaagctgctcgtcgacaaccgcatcgtgatcaacaaccacctgacc
cgcggtcgcggtggcaaggtcagcttcacccacctgatcgggtacgcgctcgtccgcgcg
gtcgtcgagcacccggagatgaacaactccttcgccgaggtcgacggcaagccggcgatg
gtccgcccggagcacgtcaacctgggcatcgcgatcgacctggtcaagccggacggctcg
cgcaacctggtggtgccgtccatcaagggctgcgagcagatggacttccggcagttctgg
caggcgtacgaggacgtggtccggcgcgcccgccgcaacgagctgaccatggaggactac
tccggcaccacgatctcgctcaccaacccgggcggcatcggcacggtgcactcgatcccg
cgcctgatgcaggggcagagcgccatcatcggcgtcggcgcgatggaatacccggccccc
taccagggcatgagcgaggccaccctggccgagaacgcggtcagcaaggtcatcacgctg
accagcacgtacgaccaccggatcatccagggcgcacagtccggcgagttcctgaaggtc
atgcacgagctgctgctcggcgagcgcggcttctacgacgacatcttcacctcgctgcgg
atcccgtacgagccggtgcgctggatgcgcgacgtggccgtcgacagcgaaggccagatc
aacaagaccgctcgggtgcacgagctgatccacgcgtaccgggtgcgcggccacctgatg
gccgacaccgacccgctggagttcaagatccgtaagcacccggacctggacgtgctccag
cacgggctcacgctctgggacctcgaccgcgtcttcccggtcaacggcttcgccggccag
cagcggatgaagctgcggtcgatcctcggcgtgctgcgcgactcgtactgccgccgggtc
ggcatcgagtacatgcacatccaggacccggaggagcggcgctggatccaggagcgggtc
gagcgcaagtacgagaagcccagctccgacgagcagaagcacgtgctgaaccggctcaac
gccgccgaggcgttcgagacgttcctccagaccaagtacgtcggccagaagcgcttctcg
ctggagggcggcgagtcgctgatcccgctgctcggcgaggtgctggagtgctccgccgag
gccgggctggacgaggtcgtcatcggcatggcccaccgcggccggctcaacgtgctggcg
aacatcgtcggcaagccgtacgagaagatcttctccgagttcgaggggcacctcgacccg
cggtccacgcagggctcgggcgacgtgaagtaccacctcggccagaacggcaagttcacc
accccggacggcgagcacgcggtcaaggtgtcggtggtggcgaacccgtcgcacctggag
gccgtggacccggtgctggagggcatcgtccgggccaagcaggaccgcatcgacctcaag
ctggagggctacaccgtgctgccgctggcggtgcacggtgacgccgccttcgccggccag
ggcgttgtggccgagacgctcaacctgtcccagctgcgcggctaccgcaccggcggcacc
gtgcacgtggtcgtcaacaaccaggtcggcttcaccaccgccccggagtacagccggtcc
agcctctacagcaccgacgtggcccggatgatccaggcgccgatcttccacgtgaacggc
gacgacccggaggccgtggtccgggtggcccggctcgcgttcgagtaccggcaggcgttc
aacaaggacgtcgtgatcgacatggtctgctaccgccggcgcgggcacaacgagggcgac
gacccgtcgatgtccaacccggagatgtacaagatcatcgactcgaagcggtccgtccgg
aagctctacaccgaggagctgatcgggcgcggcgacatcaccgtggaggacgcggaggag
ctgctgcgcgactaccaggggcagcttgagcgggtcttcaaggccacccgggacgccgcg
accaccccgcgtcagctcagccgcccggcgcgggaggaggagccggagccgcaggtcgac
accgccaccgacgccgcagtggtcaaggcgatcggcgaggcgcacgtcaacctgccggag
ggcttcaccccgcacaagcggatccagcagctgctggagcggcgccgcaagatgtccgtc
gagggcggcatcgactggggcttcgccgagatcatcgcgttcggcacgctgctgcacgac
ggggtcaccgtccggctcgccgggcaggactcgcgccgcggcacgttcgtccagcggcac
gcctcggtggtcgacgccaagaccggcgaggactacctgccgctgaagtcgctcaccgcc
gacggcgagcggtcgcgcttcttcgtccacgactcgctgctctccgagtacgcggccatg
ggcttcgagtacggctactcggtggagaacatcaacgcgctggtggcctgggaggcccag
ttcggtgacttcgtcaacggcgcccagtcggtgatcgacgagttcatctcctccggcgag
gtgaagtggggccagcgctccgcggtgaccctgctgctgccgcacggccacgagggccag
ggcccggaccacacctccggccgcccggagcggttcctccagctctgcgccgaggacaac
atgcgggtggccatcccgaccaccccggcgaactacttccacctgctgcgccgccaggcc
ctgtcgcccaagcgcaagccgctggtggtgttcacgccgaagtcgctgctgcggcacaag
ctctgcgtgtcgccggtggaggacttcaccaccgggacgttccagccggtgctggccgac
accgcggctccggcgccggagcaggtcaagcgggtgctgctctgctcgggcaaggtctac
tacgacctgttccaggcccggcaggagcggggcgtcaccgacaccgcgatcctccggatg
gagcagctctacccgctgcccgtcgaggaggtccgggccgcgctggcgcagtacccgaac
gccgaggacttcgcctgggtccaggaggagccggccaaccagggcgcctggtcgttcgtc
gcgctcaacctgctggagcacctgcccgaggtccggctgcgccgcatctcccgcccggcc
gccgccgccccggcggtcggctcggcgaagatgcacgaggtcgagcagaacgcgctgatc
gaggcggctctcccccgcccgtga
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