Mesocricetus auratus (golden hamster): 101832053 Help Entry 101832053         CDS       T08306                                  Symbol Irs1 Name (RefSeq) insulin receptor substrate 1   KO K16172   insulin receptor substrate 1 Organism maua  Mesocricetus auratus (golden hamster) Pathway maua04022   cGMP-PKG signaling pathway maua04068   FoxO signaling pathway maua04081   Hormone signaling maua04140   Autophagy - animal maua04150   mTOR signaling pathway maua04151   PI3K-Akt signaling pathway maua04152   AMPK signaling pathway maua04211   Longevity regulating pathway maua04213   Longevity regulating pathway - multiple species maua04722   Neurotrophin signaling pathway maua04910   Insulin signaling pathway maua04920   Adipocytokine signaling pathway maua04923   Regulation of lipolysis in adipocytes maua04930   Type II diabetes mellitus maua04931   Insulin resistance maua04932   Non-alcoholic fatty liver disease maua04935   Growth hormone synthesis, secretion and action maua04960   Aldosterone-regulated sodium reabsorption maua05010   Alzheimer disease maua05206   MicroRNAs in cancer maua05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:maua00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     101832053 (Irs1)    04022 cGMP-PKG signaling pathway     101832053 (Irs1)    04151 PI3K-Akt signaling pathway     101832053 (Irs1)    04152 AMPK signaling pathway     101832053 (Irs1)    04150 mTOR signaling pathway     101832053 (Irs1)   09133 Signaling molecules and interaction    04081 Hormone signaling     101832053 (Irs1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     101832053 (Irs1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101832053 (Irs1)    04923 Regulation of lipolysis in adipocytes     101832053 (Irs1)    04920 Adipocytokine signaling pathway     101832053 (Irs1)    04935 Growth hormone synthesis, secretion and action     101832053 (Irs1)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     101832053 (Irs1)   09156 Nervous system    04722 Neurotrophin signaling pathway     101832053 (Irs1)   09149 Aging    04211 Longevity regulating pathway     101832053 (Irs1)    04213 Longevity regulating pathway - multiple species     101832053 (Irs1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     101832053 (Irs1)   09164 Neurodegenerative disease    05010 Alzheimer disease     101832053 (Irs1)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     101832053 (Irs1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101832053 (Irs1)    04932 Non-alcoholic fatty liver disease     101832053 (Irs1)    04931 Insulin resistance     101832053 (Irs1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS PH PH_11 Motif Other DBs NCBI-GeneID:  101832053 NCBI-ProteinID:  XP_005082573 UniProt:  A0A1U7QZL7 LinkDB All DBs Position Unknown AA seq 1233 aa AA seqDB search MASPPDTDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADNEAEQDSWYQALLQLHNRAKAH HDGAGGGGCGGSCSGSSGVGEAGEDLSYDTGPGPAFKEVWQVILKPKGLGQTKNLIGIYR LCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQVDDSV VAQNMHETILEAMRAMSDEFRPRSKSQSSSSCSNPISVPLRRHHLNNPPPSQVGLTRRSR TESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHRGSSR LHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGG FISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGASTLTAPNGHYI LSRGGNGHRYIPGANLGTSPALTGDEATSAADLDNRFRKRTHSAGTSPTISHQKTPSQSS VASIEEYTEMMPAAYPPGGGSGGRLPSYRHSAFVPTHSYPEEGLEMHPLERRGGHHRPDT SSLHTDDGYMPMSPGVAPVPSNRKGNGDYMPMSPKSVSAPQQIINPIRRHPQRVDPNGYM MMSPSGSCSPDIGGGSSSSSGAAASGSSYGKPWTNGVGGHHSHALPHSKPPIESGGGKLL PCTGDYMNMSPVGDSNTSSPSECYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEPEEGARH QHLRLSSSSGRLLYTATAEDSSSSTSSDSLGGGYCGARPEAGLPHPHHHALQPHGPRKVD TAAQTNRRLARPTRLSLGDPKASTLPRVREQQQQQQPSLHPPEPKSPGEYVNIEFGSGQH GYLAGPATSHSSPSVRCPPQLHPAPREETGSEEYMNMDLGPGRRATWQESGGAELGRVGP APPGAATIGRPTRAVPSSRGDYMSMQIGCPRQSYVDTSPVAPVSYADMRTGIAAEKVSLP RTTGAAPSASSTASDSPAAPQGAAEQAAHSSLLGGPQGPGGMSAFTRVNLSPNHNQSAKV IRADTQGCRRRHSSETFTAPTPAGNTVSFGAGAAVGGSGGGSSSSSEDVKRHSSASFENV WLRPGDLGGASKETAQVCGAAGGLESSLNYIDLDLAKDVRQRPQECPSQQQPLPPPAPHQ PPGSNEGSSPRRSSEDLSTYASISFQKPPEDHQ NT seq 3702 nt NT seq  +upstreamnt  +downstreamnt atggcgagccctccggataccgacggcttctcggacgtgcgcaaggtgggctacctgcgc aaacccaagagtatgcacaagcgatttttcgtactgcgggcagccagcgaggccgggggc ccggcgcgcctggaatactatgagaacgagaagaagtggcggcacaagtcgagcgccccc aaacgctcgatccccctcgagagctgtttcaacatcaacaagcgggctgactccaagaac aagcacctggtggctctctacacccgagacgaacactttgccattgcggcggataacgag gctgagcaagacagctggtaccaggctcttctgcagctgcataatcgagcaaaggcccac catgacggcgccggaggtggaggctgcggtggtagttgcagcggcagctctggcgtcgga gaggcaggggaggacttgagctatgacacgggcccaggacccgcgttcaaggaggtctgg caggttatcctgaaacccaaaggtctgggtcagacaaagaacctgattggcatctaccgc ctctgcctgaccagcaagaccatcagctttgtgaagctgaactccgaggcagcggctgtg gtgctacagctaatgaacatcagacgctgtggccactcagagaacttcttcttcatcgag gtgggccgttctgccgtgacagggcccggcgagttctggatgcaagtggatgactccgtg gtagcccagaacatgcatgagaccattctagaggccatgcgggccatgagcgatgagttc cgcccacgcagcaaaagccagtcttcatccagttgctccaaccccatcagtgttcccctt cgcaggcaccatctcaacaatcctccacccagccaggtggggctgactcgccgatctcgc accgagagcatcactgccacttccccagccagcatggtgggagggaaaccaggttccttc cgagtgcgcgcctccagcgatggcgaaggcaccatgtcccgtccagcatcagtggatggt agtcctgtgagccctagcaccaacaggacccatgcccatcggcatcgagggagctccagg ctgcatccgcccctcaaccacagccgttccatccctatgccttcctcccgctgctcacct tcagccaccagcccagtgagtctgtcatccagtagcacgagtggccatggctccacctca gactgtctcttcccgagacgatctagtgcttccgtgtctggttctcctagtgatggcggt ttcatctcttctgatgagtacggttctagtccctgcgatttccgaagttccttccgcagt gtcaccccagattccttgggtcacactccaccagccaggggtgaggaagagctgagcaac tatatctgcatgggtggcaagggagcctccaccttgactgctcccaatggtcactacatt ttgtctaggggtggcaatggtcatcgctacatcccaggtgctaacttggggacaagtcca gcgttgactggggatgaagccaccagcgcagcggatctggataaccggtttcggaagaga actcactcggcaggcacgtcccctacaatttcccaccagaagaccccctcgcagtcttca gtggcttctattgaggagtatacagagatgatgcctgctgcctacccaccaggagggggc agtggaggccgactgcccagctatcggcattccgccttcgtgcccacccactcctatccc gaagagggtctagagatgcaccccttggagcgtcgtgggggccaccaccgtccagacacc tcctccttgcacactgatgatggctacatgcccatgtctcccggggtggcgccagtgcca agcaaccgtaaaggaaatggggactacatgcccatgagccccaagagtgtttctgcccca cagcagatcattaaccccatcagacgtcaccctcagagagtggaccccaatggctacatg atgatgtctcccagtggcagttgctcccctgacattggaggtgggtccagcagcagcagt ggtgcagccgcttctgggagcagctacgggaagccatggacaaatggagtaggggggcac catagtcatgccctgcctcattccaaaccccctattgagagtggcggtggcaagctcttg ccttgcacaggtgactacatgaacatgtcaccagtgggagactccaacaccagcagcccc tcagaatgctactacggcccagaagatccccagcacaagccggttctctcctactactca ttgccaaggtcttttaagcacacccagcgccctggggagccagaggagggtgccaggcac cagcatcttcgtctctcttctagctctggacgccttctctacactgcaactgcagaagat tcttcctcttctaccagcagtgacagcttgggtgggggttactgtggggctaggccagag gctggcctcccgcatccccaccaccatgccttgcaaccccatgggcctcgaaaggtagac acggctgcgcagaccaaccgccgtctggcccggcccacaaggctctccttgggagatccc aaggcaagcaccttaccccgggtacgggagcagcagcagcagcagcaaccttcgctgcac cctccggagcccaagagcccgggggaatatgtgaatattgaattcgggagtggccagcat ggctatttagctggccctgcaacttcccatagctctccttcagttcggtgtccaccccag ctccacccagctccccgagaagagactggctcggaagagtacatgaacatggatttgggg ccaggcagaagggcaacctggcaggagagtggtggggctgagttgggtagagtaggccct gcacctccaggggctgctaccattggcaggccaacccgggcagtgccaagtagccgtggt gactacatgagcatgcagataggttgtcctcgtcaaagctatgtggatacctcaccagtg gccccagtcagctatgctgacatgcggacaggcattgcggccgagaaggtgagcctgccc agaaccacaggggctgctccatctgcatcctccacagcctctgattctcctgctgcacct caaggagcagctgagcaggctgctcactcttctctgctgggaggccctcagggacctggg ggcatgagtgcattcaccagagtgaacctcagtcccaaccataaccagagtgccaaagtg attcgtgcagacactcaaggctgccggaggaggcacagctccgagaccttcacagcacct actccagctggcaacacggtgtcctttggagcaggggctgcagtagggggcagtggcggg ggcagcagcagcagcagtgaggatgtaaaacgccacagctctgcatcatttgagaatgtg tggctgagacctggggatctagggggagcctccaaggagacagctcaagtgtgtggggct gctgggggtttggagagtagtcttaactacatagacctggatttggccaaggatgttaga cagcgtcctcaggaatgcccttctcaacagcagcctcttccaccccctgcccctcaccag cctccaggcagcaacgagggcagctcccccagacgctccagtgaggatttaagcacctat gccagcatcagcttccagaagccgccagaggaccatcaatag

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