Mesocricetus auratus (golden hamster): 101837225 Help Entry 101837225         CDS       T08306                                  Symbol Lck Name (RefSeq) tyrosine-protein kinase Lck   KO K05856   lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2] Organism maua  Mesocricetus auratus (golden hamster) Pathway maua04064   NF-kappa B signaling pathway maua04380   Osteoclast differentiation maua04517   IgSF CAM signaling maua04650   Natural killer cell mediated cytotoxicity maua04658   Th1 and Th2 cell differentiation maua04659   Th17 cell differentiation maua04660   T cell receptor signaling pathway maua05135   Yersinia infection maua05166   Human T-cell leukemia virus 1 infection maua05235   PD-L1 expression and PD-1 checkpoint pathway in cancer maua05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:maua00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     101837225 (Lck)   09133 Signaling molecules and interaction    04517 IgSF CAM signaling     101837225 (Lck)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     101837225 (Lck)    04660 T cell receptor signaling pathway     101837225 (Lck)    04658 Th1 and Th2 cell differentiation     101837225 (Lck)    04659 Th17 cell differentiation     101837225 (Lck)   09158 Development and regeneration    04380 Osteoclast differentiation     101837225 (Lck)  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     101837225 (Lck)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101837225 (Lck)   09171 Infectious disease: bacterial    05135 Yersinia infection     101837225 (Lck)   09163 Immune disease    05340 Primary immunodeficiency     101837225 (Lck)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:maua01001]     101837225 (Lck)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:maua03036]     101837225 (Lck) Enzymes [BR:maua01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      101837225 (Lck) Protein kinases [BR:maua01001]  Non-receptor tyrosine kinases   SRC family    101837225 (Lck) Chromosome and associated proteins [BR:maua03036]  Eukaryotic type   Centrosome formation proteins    Kinases and associated factors     101837225 (Lck) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 ABC1 SH2_1 DUF7251 Haspin_kinase SH3_16 SH3_3 Motif Other DBs NCBI-GeneID:  101837225 NCBI-ProteinID:  NP_001297497 UniProt:  V5IZL0 LinkDB All DBs AA seq 509 aa AA seqDB search MGCVCSSNPEDDWMENIDVCENCHYPIVPLDSKTTLPIRNGSEVRDPLVTYEGSLPPASP LQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKAN SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH YKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTKLSRPCQTQKPQKPWWEDEWEV PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGIMSPDAFLAEANLMKQLQHPRL VRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLNINKLLDMAAQIAEGMAFIEEQNY IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYHLMMLCWKER PEDRPTFDYLRSVLDDFFTATEGQYQPQP NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgggctgtgtctgcagctcaaaccctgaagatgactggatggagaacattgatgtgtgt gaaaactgccattatcccatagtcccgctggatagcaagaccacgctgcccatccggaat ggctctgaagttcgggacccactggtcacctatgagggctccctcccaccagcctccccg ctgcaagacaacctggttatcgctctgcacagctatgaaccctcccatgatggagacctt ggttttgagaagggtgaacagctccgaatcctggagcagagcggtgagtggtggaaggct cagtccctgaccaccggccaagaaggcttcatccccttcaacttcgtggcgaaagcaaac agcctggagcctgaaccctggttcttcaagaatctgagccgtaaggacgctgagcggcag cttttggcgcctgggaacacgcacggatccttcctgatccgggaaagtgaaagcacagcg ggatctttttcactgtcggtcagagacttcgaccagaaccaaggagaagtggtgaaacat tacaagatccgtaacctagacaacggtggcttctacatctcccctcgtatcacttttccc ggactacacgaactggtccgccattacaccaatgcctctgatgggctgtgcacaaagttg agccgtccttgccagacccagaagccccagaaaccgtggtgggaggatgaatgggaggtt cccagggagacactgaagttggttgagcggctgggagctggccagtttggggaagtgtgg atggggtactacaacggacacacgaaggtggcggtgaagagtctgaaacaaggaatcatg tcccccgacgccttcctggctgaggctaacctcatgaagcagctgcagcacccgcggcta gtccggctttatgcagtggtcacccaggaacccatctacatcatcacagaatacatggag aacggaagcctagtagattttctcaagactccctcaggcatcaagttgaacatcaacaaa ctgttggacatggcagcacagatcgcagagggtatggcattcattgaagagcagaattac atccatcgcgacctgcgggctgccaacatcctggtgtctgacacactgagctgcaagatt gcagactttggcctggcacgtctcattgaggacaatgagtacacagccagggagggggcc aaatttcccatcaagtggacagcaccagaagccattaactatgggaccttcaccatcaaa tcggatgtgtggtctttcgggatcctgctgacagagattgtcacccatggccgaatccct tacccagggatgaccaaccctgaagtgattcaaaatctggagcgaggctaccgcatggtt cgacctgacaactgtccagaagagctgtaccacctcatgatgctgtgctggaaggagcgt ccagaggaccggcccacgtttgactaccttcgaagcgttctggatgacttcttcacagcc acagagggccagtaccagccccagccttga

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