Mesocricetus auratus (golden hamster): 101842209 Help Entry 101842209         CDS       T08306                                  Symbol Jak3 Name (RefSeq) tyrosine-protein kinase JAK3   KO K11218   Janus kinase 3 [EC:2.7.10.2] Organism maua  Mesocricetus auratus (golden hamster) Pathway maua04062   Chemokine signaling pathway maua04151   PI3K-Akt signaling pathway maua04217   Necroptosis maua04550   Signaling pathways regulating pluripotency of stem cells maua04630   JAK-STAT signaling pathway maua04658   Th1 and Th2 cell differentiation maua04659   Th17 cell differentiation maua05161   Hepatitis B maua05162   Measles maua05166   Human T-cell leukemia virus 1 infection maua05169   Epstein-Barr virus infection maua05200   Pathways in cancer maua05203   Viral carcinogenesis maua05223   Non-small cell lung cancer maua05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:maua00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101842209 (Jak3)    04151 PI3K-Akt signaling pathway     101842209 (Jak3)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     101842209 (Jak3)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     101842209 (Jak3)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     101842209 (Jak3)    04659 Th17 cell differentiation     101842209 (Jak3)    04062 Chemokine signaling pathway     101842209 (Jak3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101842209 (Jak3)    05203 Viral carcinogenesis     101842209 (Jak3)   09162 Cancer: specific types    05223 Non-small cell lung cancer     101842209 (Jak3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101842209 (Jak3)    05161 Hepatitis B     101842209 (Jak3)    05162 Measles     101842209 (Jak3)    05169 Epstein-Barr virus infection     101842209 (Jak3)   09163 Immune disease    05340 Primary immunodeficiency     101842209 (Jak3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:maua01001]     101842209 (Jak3) Enzymes [BR:maua01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      101842209 (Jak3) Protein kinases [BR:maua01001]  Non-receptor tyrosine kinases   JAK family [OT]    101842209 (Jak3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 FERM_F1 Jak1_Phl Kdo pKID Kinase-like Ppx_C ABC1 FERM_M Haspin_kinase Motif Other DBs NCBI-GeneID:  101842209 NCBI-ProteinID:  XP_040598052 EnsemblRapid:  ENSMAUG00000010255 LinkDB All DBs Position Unknown AA seq 1100 aa AA seqDB search MAPPGEETPLVPRRSCSLSSSEAGSLHVLLPPRGPGPPQRLSFSFGDYLAEDLCVQAAKA CGILPVYHALFALATEDLSCWFPPSHIFSVEDVDTQVLVYRLRFYFPDWFGLETCHRFGL RKDLTSAILDSHVLEHLFAQHRSDLVSGRLPVGLSLKEQGECLSLAVLDLAQMAREQAQR PGELLKAVSYKACLPPGLRDLIQGLSFVTRRRIRRTVLQALRRVVACQADRYSLMAKYIL DLERLHPAAAAETFRVGLPGAQEGPALLRVAGGSGVAWSPGDQELFQTFCDFPEIVDVSI KQAPRVGPAGEHRLVTVTRMDSHALEAEFPGLPEALSFLALVDGYFRLTCDSRHFFCKEV APPRLLEEVAELCHGPITLDFAIHKLKAAGSRPGSYILRRSPQDYDSFLLNACVQTPLGP DYKGCLIRRDPTGAFSLVGLSQPHRSLRELLAACRHSGLHVDGTELNLTLCCSPRPKEKS NLIVVRRGCTPAPPPGRAPSCCALTQLTFHTIPADSLEWHENLGHGSFTKIYRGRRREAV DGETHDTEVLLKVMDARHRNCMESFLEAASLMSQVSYPHLVLLHGVCMAGDSIMVQEFVH LGALDMYLRKRGPLVPASWKLQVAKQLAYALNYLEDKGLPHGNVSARKVLLAREGMDGSP PFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEARTLGLEADKWGFGATVWEVFSGGPL HITSLEPAKKLKFYEDQGQLPAPKWTELAGLIAQCMAYDPGRRPSFRAILRDLNGLITSD YELLSDPTPGSLSPRDELCSGAQLHACPDPTVFEERHLKYISLLGKGNFGSVELCRYDPL GDNTGPLVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEF LPSGCLRDFLQRHRARLHTGRLLLFAWQICKGMEYLGARRCVHRDLAARNILVESEAHVK IADFGLAKLLPLGKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYS DKSCSPSAEFLRMLGPERDGPALCRLLELLAEGRRLPPPPACPMEVQELMQLCWAPSPQD RPAFSALSPQLDALWRGNPG NT seq 3303 nt NT seq  +upstreamnt  +downstreamnt atggcgcctcccggcgaggagacgccgctggtccctcgacgctcttgcagcctgtcgtcc tcggaggcagggtccctgcatgtcctccttcctccccggggacctgggcctccccagagg ctgtcattctcttttggggactacctggcggaggatctgtgcgtgcaggcggccaaggcc tgtggcatcctgcctgtctatcacgcgctcttcgctctggccacggaggacttgtcttgc tggttccccccgagccacatcttctccgtggaggacgtggacacccaggtcttggtctac aggctccgcttctattttcctgactggtttgggctggagacttgccaccgcttcgggctg cgcaaagatttgaccagtgccattctcgactcgcatgttttggaacacctctttgcccag caccgcagtgacctggtgagcgggcgcctcccagtgggcctcagcctgaaggagcaggga gagtgcctgagcctggcggtgttggacctggcccagatggctcgcgagcaggcccagcgg ccaggcgagctgctgaaggccgtcagctacaaggcctgcctgccacccggcctgcgcgac ctgatccaaggactgagcttcgtgacgcgcaggcgcatccgcaggaccgtgctccaggct ctgcgtcgcgtggtcgcctgccaggccgaccgctactcgctcatggccaagtacatcctg gacctggagcggctgcacccggcggccgccgccgagaccttccgcgtggggctcccgggt gcccaggaggggccggcgctcctgcgcgtggctgggggcagcggcgtcgcctggagcccc ggggaccaggagctcttccagaccttctgtgactttcccgaaatcgtggacgtcagcatc aagcaggccccgcgcgtgggtccggccggggagcaccggctggtcaccgtcaccaggatg gacagccacgccctggaggcggagttcccggggctgcccgaggcgctgtccttcctggcc ctcgtggatggctacttccgcctgacctgcgactccaggcacttcttctgcaaggaggtg gcgccgccaaggctgctggaggaggtggcagagctgtgccacgggcccatcacgctagac ttcgccatccacaagctgaaagccgccggctcccgcccgggctcctacattctccgccgc agcccgcaggactatgacagttttcttctcaatgcctgcgttcagacgccccttggcccg gactacaagggctgcctcatccgccgggaccccacgggggccttctccctggttggcctc agccagcctcaccgaagtctccgggagctccttgcagcctgcaggcattctgggctgcac gtcgatggtaccgaactgaacctcacactctgctgctcgcccaggcccaaggaaaagtcc aatttgatcgtggtgagaaggggctgcacccctgccccaccccctggccgtgccccatcc tgctgtgcactgacccagctgaccttccacacgatccctgctgacagcctggagtggcac gagaacctgggccatggctctttcaccaagatctaccgaggccgccgtcgggaggccgtg gacggtgagactcacgacacggaagtcctcttgaaggtcatggatgccaggcaccggaac tgcatggagtcctttctggaagccgcaagcctgatgagccaagtatcctacccgcacctg gtgctgctgcatggcgtctgcatggctggagacagcatcatggtgcaggagtttgtccac ctaggagcacttgacatgtacctacgcaagcgcgggcccctggtgccggccagctggaag ctgcaggtggccaagcagctagcctacgccctcaactacttggaggacaaaggcctccct catggcaacgtgtcagcacggaaggtgctcctggctcgcgaggggatggatgggagccca cccttcatcaaactgagtgaccctggcgtcagccccacggtgctgagcctggaaatgctc actgacaggatcccctgggtggcccccgagtgtctgcaggaagccaggacgctcggcttg gaagcggacaagtggggctttggcgccaccgtgtgggaggttttcagcgggggacccttg cacatcacctcgctggagcccgccaagaagctgaagttctacgaggaccaggggcagctg ccggcccccaagtggacggagctggcggggctcatcgcgcagtgcatggcctacgatccc ggccggcggccctccttccgcgccatcctcagggacctcaacggcctcatcacgtcagac tatgagctcctctcagacccgacacccggcagcctgagcccccgagacgagctgtgcagt ggcgcccagctccacgcctgcccggaccccaccgtctttgaggagaggcacctgaagtac atctctctgctgggcaagggcaacttcggcagcgtggagctgtgccgctacgaccctctg ggggataacacgggacccctggtggcagtgaagcagctgcagcacagcgggccagaccag cagagggacttccagcgggagattcagatcctcaaggcgctgcacagcgacttcatcgtc aagtaccggggagtcagctacggtccgggtcgccagagcctgcggctggtgatggagttc ctgcccagcggctgcctgcgggacttcctgcagcgccaccgcgcgcgcctgcacaccggc cgcctgctgctgttcgcctggcagatctgcaagggcatggagtacctgggcgcgcgccgc tgcgtgcaccgcgatctggctgcgcggaacatcctggtggagagcgaggcgcacgtgaag atcgcggacttcggcctcgcgaagctgctgccgctcggaaaggactactacgtggtccgc gagccgggccagagccccatcttctggtacgccccagaatccttgtctgacaacatcttc tcccgccagtctgacgtgtggagcttcggcgtggtgctgtacgagctcttcacctacagc gacaagagctgcagcccgtccgcagagttcctgcgcatgttggggcctgagcgtgatggg ccagcgctctgccgcctgctggagttgctggccgagggccgccgcctcccgccacctcct gcctgccccatggaggtccaggagctcatgcagctgtgctgggctcccagcccgcaggac cggccggccttcagcgccctgagcccacagctggacgcactgtggcgtggaaaccctggg tag

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