KEGG   Mesocricetus auratus (golden hamster): 121142382
Entry
121142382         CDS       T08306                                 
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2-like isoform X1
  KO
K00070  3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
Organism
maua  Mesocricetus auratus (golden hamster)
Pathway
maua00140  Steroid hormone biosynthesis
maua01100  Metabolic pathways
maua04913  Ovarian steroidogenesis
maua04925  Aldosterone synthesis and secretion
maua04927  Cortisol synthesis and secretion
maua04934  Cushing syndrome
Module
maua_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
maua_M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
maua_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:maua00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    121142382
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    121142382
   04925 Aldosterone synthesis and secretion
    121142382
   04927 Cortisol synthesis and secretion
    121142382
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    121142382
Enzymes [BR:maua01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.145  3beta-hydroxy-Delta5-steroid dehydrogenase
     121142382
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.3  Transposing C=C bonds
    5.3.3.1  steroid Delta-isomerase
     121142382
SSDB
Motif
Pfam: 3Beta_HSD Epimerase NAD_binding_4 GDP_Man_Dehyd Polysacc_synt_2 NAD_binding_10 NmrA RmlD_sub_bind KR Ldh_1_N Sacchrp_dh_NADP Cytochrom_B558a
Other DBs
NCBI-GeneID: 121142382
NCBI-ProteinID: XP_040608090
LinkDB
Position
Unknown
AA seq 396 aa
MYAISRITLHYPLPSLDLFPVLAMPGWSCLVTGAGGFLGQRIIHLLVQEKDLEEVRLLDK
VFRPETREEFFKLQTKTKVTVMEGDILDAQCLRRACQGISVVIHTAAAIDVWGIIPRQTI
IDINVKGTLNLLEACVQASVPAFIYTSSIDVAGPNSYKEIVLNGHEEQQHESTWSDPYPY
SKKMAEKAVLAANGSTLKNGGTLHTCALRPMYIYGEKSSLLSGIMIRAIKNNGILNVTGK
FSTVNPVYVSNAAWAHILAARGLQDPRKSPNIQGQFYYISDDTPYQSYDDLNYALSKDWG
LRPDSSWSPPVALLYWLGFLLELVSFLLRPVYNYQPPFNRHLVTLSNTVFTFSYKKAQRD
LGYEPLVSWEEARENTSEWIGSLVEQHKGTLNTKAQ
NT seq 1191 nt   +upstreamnt  +downstreamnt
atgtatgccatctccagaatcaccctacattacccgctgccctcgctggatctgtttcct
gtgttggccatgcctggatggagctgcttggtgacaggggctggagggtttctggggcaa
aggattatccacttgctggtacaggagaaggatctggaagaggtcagactcctggacaag
gtgttcagaccagaaaccagggaggaattcttcaagctgcagacaaagaccaaggtgaca
gtgatggagggtgacattctggatgcccagtgcctgaggagagcctgccagggcatctcc
gttgtcatccacactgctgctgccattgacgtctggggtatcattcccagacagaccatc
atagatatcaatgtgaaaggtaccctgaacctgttggaggcctgtgtccaggctagtgtg
ccagccttcatctacaccagctcaattgatgttgcggggcccaactcctacaaggaaatc
gtcctaaatggccatgaggaacaacagcatgaaagcacatggtctgatccatacccatac
agcaaaaagatggctgagaaggcagtgctggcagccaatgggtccaccctgaaaaatggt
ggcactttgcatacttgtgccttaaggcctatgtacatctatggggaaaaaagctcatta
ctttcagggataatgattagggccatcaaaaataatggtattctgaatgttactggaaaa
ttctccacagtcaacccagtgtatgtgagtaatgcagcctgggcacacattctggctgcc
aggggcctacaagaccccaggaagtcaccaaacatccaaggacagttctactacatctca
gatgacaccccttaccaaagctatgatgatttaaattatgccctgagcaaggactggggc
ctccgccctgattccagttggagtcctcctgtggccctgctgtactggcttggcttcctg
ctggaattggtgagcttcctgctgcgtccagtctacaactaccagcctcccttcaaccga
cacttggtcacactctcaaatactgtgttcaccttctcctacaagaaagctcagcgagat
ctgggctatgagccccttgtcagctgggaggaagccagggagaacacttcagagtggatc
gggtcactggtggagcagcacaagggaacactgaacacaaaggctcagtga

DBGET integrated database retrieval system