Mycolicibacterium aurum: NCTC10437_04206
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Entry
NCTC10437_04206 CDS
T06794
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mauu
Mycolicibacterium aurum
Pathway
mauu00020
Citrate cycle (TCA cycle)
mauu00630
Glyoxylate and dicarboxylate metabolism
mauu00785
Lipoic acid metabolism
mauu01100
Metabolic pathways
mauu01110
Biosynthesis of secondary metabolites
mauu01120
Microbial metabolism in diverse environments
mauu01200
Carbon metabolism
mauu01210
2-Oxocarboxylic acid metabolism
Module
mauu_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mauu_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mauu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
NCTC10437_04206 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
NCTC10437_04206 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
NCTC10437_04206 (kgd)
Enzymes [BR:
mauu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
NCTC10437_04206 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
NCTC10437_04206 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
NCTC10437_04206 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
NCTC10437_04206 (kgd)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
VEG57199
UniProt:
A0A3S4VRM9
LinkDB
All DBs
Position
1:4474592..4478350
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AA seq
1252 aa
AA seq
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MYRKFREDPSSVDPSWHEFLVDYSPEPTNDAPSGGANRAAASGNGKPAKTPTAPPEPAPA
PKPANTNGGSAAPAKSDKPSGTSAKTPEKTPAKSPEKAPEKASEKAEAKSAPAPAKSKAA
TPAADGDESQILRGAAAAVVKNMSASLDVPTATSVRAIPAKAMIDNRIVINNHLKRTRGG
KISFTHLLGYAIVQAVKKFPNMNRHFAEVDGKPNAVTPAHTNLGLAIDLPGKDGKRSLVV
AAIKNCETMSFGQFIAAYEDIVRRARDGKLTGEDFAGVTISLTNPGTIGTVHSVPRLMQG
QGAIVGAGAMEYPAEFQGASEERISELGVGKLITLTSTYDHRIIQGAESGDFLRTIHTLL
LDDEFYDEIFRELGIPYEPVRWRIDNPDSIEDKNARVIELIAAYRNRGHLMADIDPLRLD
NTRFRSHPDLDVNTHGLTLWDLDREFKVNGFGGQSHKKLRDILGLLRDAYCRHVGVEYTH
ILEPEQQQWLQERIEVKHEKPTVAEQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGAET
VIPMMDAGIDQCAEHGLDEVVIGMPHRGRLNVLANIVGKPYSQIFTEFEGNLNPSQAHGS
GDVKYHLGANGTYIQMFGDNDISVSLVANPSHLEAVDPVLEGLVRAKQDILDKGNGPDGF
TVVPMMLHGDAAFAGQGVVAETLNLALLRGYRTGGTIHIIVNNQIGFTTSPIDSRSSEYC
TDVAKMIGAPIFHVNGDDPEAAVWVAKLAVDFRQKFKKDVVIDMLCYRRRGHNEGDDPSM
TQPDMYDVIDTKRGVRKTYTESLIGRGDISMKEAEDALRDYQGQLERVFNEVRELEKHAI
APSESVEADQMVPAGMSTAVDKSLLARIGDAHLAFDEEFSVHPRVKPVLEKRREMAYEGK
VDWAFAELLALGTFLAEGKTIRFTGQDTRRGTFTQRHAVIIDRKTGKEFTPLDLLTVDTD
GNPTGGKLMIYDSALSEFAAVGFEYGYSVGNPDALVLWEAQFGDFVNGAQSIIDEFISSG
EAKWGQLSDVVLLLPHGHEGQGPDHTSGRIERFLLLWAEGSMTIAVPSTPANYFHLLRRH
GLDGIHRPLIVFTPKSMLRNKAAVSDIRDFTEQKFRSVLEEPTYTDGTGDRSKVERVLLT
SGKIYYELAARKNKDKREDVAIVRLEQLAPLPKRRLAETLDQYPNADTFFWVQEEPANQG
AWPTLGLTLPEVMPDKLVGIKRISRRAMSAPSSGSSKVHAVEQQEIIDLAFG
NT seq
3759 nt
NT seq
+upstream
nt +downstream
nt
atgtaccgcaagttccgcgaggacccgtcgtcggtcgacccgagttggcacgagttcctc
gtcgactactccccggaacccacgaacgacgcgccgtccggtggcgccaaccgcgcggcc
gcgagcggcaacggcaagcccgcgaagacgcccaccgctccccccgaacccgcgcctgcc
cccaagcccgcgaacaccaacggcggttccgccgctccggccaagtccgacaagcccagc
ggcacgtcggcaaagacccccgagaagacgccggcgaagtcgcccgagaaggcccccgag
aaggcgtccgagaaggccgaagcgaagtcggctccggcgcccgcgaagagcaaggccgcg
accccggccgccgacggcgacgagtctcagatcctgcgcggcgccgcggcagccgtcgtg
aagaacatgtcggcgtcgctggacgtgccgaccgccaccagcgtgcgggccatccctgcc
aaggcgatgatcgacaaccgcatcgtcatcaacaatcacctcaagcgcacccgcggcggc
aagatctcgttcacccacctgctgggctacgcgatcgtgcaggccgtcaagaagttcccg
aacatgaaccggcacttcgccgaggtcgacggcaagcccaacgcggtcacaccggcgcac
accaacctcggtctggccatcgacctgcccggcaaggacggcaaacgctcgctggtggtg
gctgccatcaagaactgcgagacgatgagcttcggtcagttcatcgcggcctacgaggac
atcgtgcgacgggcccgcgacggcaagctgacgggcgaagactttgcgggcgtgacgatt
tcgctgaccaacccgggcaccatcgggaccgtgcactcggtgccgcggttgatgcagggc
cagggcgcgatcgtcggcgcaggcgccatggagtaccccgccgaattccagggcgccagc
gaggagcgcatctccgagctcggcgtcggcaagctgatcacgctgacgtccacctacgac
caccgcatcatccagggagcggagtcgggcgacttcctgcgcacgatccacacgctgctt
ctcgacgacgagttctacgacgagatcttccgcgaactcgggatcccgtacgagccggtg
cgctggcgcatcgacaacccggattcgatcgaggacaagaacgcgcgcgtcatcgagctg
atcgcggcctaccgcaaccgcggtcacctgatggccgacatcgacccgctgcggctggac
aacacccgcttccgcagccacccggacctcgacgtcaacacccatgggctcacgctgtgg
gatctggatcgcgagttcaaggtcaacgggttcggcggccagagccacaagaagctgcgg
gacatcctggggctgctgcgcgacgcgtactgccggcatgtgggcgtggagtacacccac
atcctcgagcccgagcagcagcagtggctgcaggagcgcatcgaggtcaagcacgagaag
ccgacggtcgccgagcagaagtacattctgagcaagctcaacgccgcggaggcgttcgag
accttcctgcagacgaaatacgttgggcagaagcgtttctcgcttgaaggtgccgaaacc
gtgatcccgatgatggatgccggcatcgaccagtgcgccgaacacggtctcgacgaggtc
gtcatcggcatgccgcaccgcgggcggctcaacgtgctggccaacatcgtcggcaagccg
tactcgcagatcttcaccgagttcgagggcaacctcaacccgtcgcaggcgcatggttcc
ggcgacgtgaagtaccacctgggcgccaacggcacctacatccagatgttcggcgacaac
gacatctccgtgtccctggtcgccaaccccagccacctggaagccgtcgaccccgtgctc
gagggtctggtgcgcgccaagcaggacatcctcgacaagggcaacgggcctgatggcttc
accgtcgtgccgatgatgctgcacggcgacgccgccttcgccggccagggtgtggtcgcc
gagacgctgaacctggcgctgctgcgcgggtaccgcaccggcggaaccatccacatcatc
gtcaacaaccagatcgggttcaccacctcgccgatcgactcgcgctcctcggagtactgc
accgacgtcgcgaagatgatcggcgcgccgatcttccacgtcaacggcgacgatccggag
gccgcggtctgggtcgccaagctggctgtcgacttccggcagaagttcaagaaagacgtc
gtcatcgacatgctgtgctaccggcgccgcggtcacaacgagggcgacgacccgtcgatg
acccagcccgacatgtacgacgtcatcgacaccaagcgcggcgtccgcaagacctacacc
gagtccctcatcggccgcggcgacatctcgatgaaggaagccgaggacgccctgcgcgac
taccagggacagctcgagcgggtgttcaacgaggtgcgcgagctggagaagcacgccatc
gcccccagcgagtcggtggaagccgaccagatggtgcctgccggcatgagtacggcggtg
gacaagtcactgctggcccgcatcggcgatgcacacctggcgttcgacgaggagttcagc
gtccacccgcgcgtcaagcccgtgctggagaagcgtcgggagatggcctacgagggcaag
gtcgactgggcgttcgccgagctgctggccctcggcacgttcctggccgagggcaagacc
atccggttcaccggtcaggacacccgccgcggcacgttcacccagcgccacgcggtgatc
atcgaccgcaagaccggcaaggagttcaccccgctggacctgctgacggtcgacaccgac
ggcaacccgaccggcggcaagttgatgatctacgactccgcgctctcggagttcgccgcc
gtgggcttcgagtacggctactcggtgggcaacccggatgcgttggtgttgtgggaagcg
cagttcggtgacttcgtcaacggcgcgcagtcgatcatcgacgagttcatcagctccggc
gaggccaagtggggccagctctccgacgtggtgctgttgctgccgcacggccacgagggc
cagggcccggaccacacctcgggccgcatcgagcggttcctgttgctgtgggccgaaggc
tcgatgacgatcgcggtgccgtcgacgccggccaactatttccacctgttgcgccgtcat
ggcctcgacgggatccaccgcccgctgatcgtgttcaccccgaagtcgatgctgcgcaac
aaggccgccgtcagcgatatccgcgatttcaccgagcagaagttccgctcggtgctcgag
gagcccacctacaccgacggcaccggcgatcgcagcaaggtcgagcgggtgctgctcacc
agcggcaagatctactacgagctggcggcccgcaagaacaaggacaagcgcgaagacgtc
gcgatcgtccggctggagcagctggctccgctgccgaagcgccggctggccgaaacgctc
gaccagtacccgaacgccgacacgttcttctgggtgcaggaggagccggccaaccaggga
gcatggccgacgctgggtctcacgctgcccgaggtgatgcccgacaagctggtcggcatc
aaacggatctcacgccgggcgatgtcggctccgtcgtcggggtcgtcgaaggtgcacgcc
gtcgagcagcaggagatcatcgacctggccttcggctag
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