Mycobacterium avium subsp. paratuberculosis E1: RC58_09150
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Entry
RC58_09150 CDS
T03787
Name
(GenBank) pyruvate dehydrogenase
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mavi
Mycobacterium avium subsp. paratuberculosis E1
Pathway
mavi00010
Glycolysis / Gluconeogenesis
mavi00020
Citrate cycle (TCA cycle)
mavi00620
Pyruvate metabolism
mavi00785
Lipoic acid metabolism
mavi01100
Metabolic pathways
mavi01110
Biosynthesis of secondary metabolites
mavi01120
Microbial metabolism in diverse environments
mavi01200
Carbon metabolism
mavi01210
2-Oxocarboxylic acid metabolism
Module
mavi_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mavi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
RC58_09150
00020 Citrate cycle (TCA cycle)
RC58_09150
00620 Pyruvate metabolism
RC58_09150
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
RC58_09150
Enzymes [BR:
mavi01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
RC58_09150
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AJK75173
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All DBs
Position
complement(1987007..1989796)
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AA seq
929 aa
AA seq
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MTTEFVRHDLATNPTGPAEPDRVRVIREGVASYLPDIDPEETSEWLESFDELLERSGPSR
ARYLMLRLLERAGEQRVALPSLTSTDYVNTIPTELEPWFPGDEDVERRYRAWIRWNAAIM
VHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKSHPGGGDQIFIQGHASPGIYARAF
LEGRLTADQLDGFRQEHSHAGGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHY
LHDRGIKDTSDQHVWCFLGDGEMDEPESRGLIQVAANEALDNLTFVINCNLQRLDGPVRG
NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDGDYQTYKANDG
AYVRDHFFGRDPRTKALVENMTDAEIWNLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKT
IKGYSLGAHFQGRNATHQMKKLALEDLKHFRDAMRIPISDAQLDENPYLPPYYHPGSDAP
EIRYMLDRRRTLGGFLPERRTKAKALRLPGRDIYAALKKGSGTQEVATTMATVRTFKEVL
RDKEIGPRIVPIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDAELMLAYKESEVGQILH
EGINEAGSVGSFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDGLWAAADQMTRGFLLGA
TAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEIAYIVESGLARMFGENPEDVY
FYITVYNEPYVQPPEPENFDPEGLLRGLYRYHVATEQRANKAQILASGVAMPSALNAAKM
LADEWDVAADVWSVTSWGELNRDGVAIDRARLRHPDRPAGVPYVTQALSDASGPVVAVSD
WMRAVPEQIRPWVPGTYVTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALARDGEID
PSVPVAAARQYRIDDVLAAPEQTSDPGVA
NT seq
2790 nt
NT seq
+upstream
nt +downstream
nt
ttgacaaccgaattcgtgcgccacgatctggccacaaaccccaccggcccggccgaaccc
gaccgcgtccgggtgatccgcgagggggtcgcgtcctacctccccgacatcgacccggaa
gagacgtcggagtggctggagtccttcgacgaactgctggagcgctccgggccgtcacgg
gcccgctatctgatgctgcggctgctggaacgcgccggcgagcagcgggtcgccctcccg
tcgctgacctccaccgactacgtcaacaccattcccaccgaactcgagccgtggttcccc
ggcgacgaggacgtcgaacggcgctaccgggcgtggatccggtggaacgccgccatcatg
gtgcaccgcgcgcagcggccgggagtcggtgtgggcggccacatttcgacctacgcgtcg
tcggcggcgctgtacgaagtcggcttcaaccacttcttccgcggcaagtcgcatcccggc
ggcggcgaccagatcttcatccagggccacgcctccccggggatctacgcgcgcgccttc
ctggagggccggttgaccgccgaccaactcgacggcttccgccaggagcacagccacgcc
ggcggcggcctgccgtcctacccgcacccacggctgatgcccgacttctgggaattcccc
acggtgtcgatgggcctgggcccgctgaacgccatttatcaggcgcggttcaaccactac
ctgcatgaccgcggcatcaaggacacctccgatcagcacgtgtggtgcttcttgggcgac
ggcgagatggacgagccggaaagccgcggtctgatccaggtggccgccaacgaggcgctg
gacaacctgacgttcgtgatcaactgcaacctgcagcgcctcgacggcccggtgcgcggc
aacggcaagatcattcaggaactggagtcgttcttccgcggcgccggctggaacgtcatc
aaggtggtctggggccgcgagtgggacgccctgctgcacgccgaccgggacggcgcgctg
gtgaacctgatgaacaccacgcccgacggggattaccagacctacaaggccaacgacggc
gcctacgtgcgcgaccatttcttcggccgcgacccgcgcaccaaggcgctggtggagaac
atgaccgacgccgagatctggaacctcaagcgcggcggccacgactaccgcaaggtgtat
gccgcctaccgggccgccgtcgaccacaagggccagcccacggtgatcttggccaagacc
atcaagggctactcgctgggcgcgcacttccagggccgcaacgccacgcatcagatgaaa
aagcttgcgctggaagacctcaagcacttccgggacgcgatgcgcattccgatcagcgac
gcccagctggacgagaatccctatctgccgccctactaccaccccggctccgatgccccc
gagatccgctacatgctcgaccggcgccgcaccctgggtggctttctgcccgaacgccgc
accaaggcaaaggcattgaggcttcccggccgcgacatctacgccgcactgaagaagggg
tcgggcacccaggaggtcgccaccaccatggcgacggtgcgcaccttcaaagaagtattg
cgggacaaggagattggcccgcggatcgtgccgatcattcccgacgaggcgcgcaccttc
ggcatggactcctggttcccgtcgctgaagatctacaaccgcaacggccagctgtacacc
gccgtggacgccgaattgatgttggcgtacaaggaaagcgaagtcgggcagatcctgcac
gagggcatcaacgaagccggatcggtgggatcgttcatcgcggccgggacgtcgtatgcc
acgcacaacgagccgatgatcccgatctacatcttctattcgatgttcggcttccagcgc
accggtgacgggctgtgggccgccgccgaccagatgacacgcggcttcctgctcggcgcg
acggcggggcgcaccaccctgaccggcgagggcctgcaacacgccgacggccactcgctg
ctgctggccgccaccaacccggccgtggtcgcctacgacccggcgttcgcctacgagatc
gcctacatcgtggagagcgggctggcacggatgttcggcgagaaccccgaggacgtgtac
ttctacatcaccgtctacaacgagccgtacgtgcagccgccggagccggagaacttcgat
cccgagggcctgctgcgcggcctctaccgctaccacgtggccaccgaacagcgcgccaac
aaggcgcagatcctggcctccggggtggccatgccgtcggcgctgaacgcggcgaagatg
ctggccgacgagtgggacgtggccgccgacgtgtggtcggtgaccagctggggcgagttg
aaccgcgacggcgtggcgatcgaccgggccaggctgcggcacccggaccggcccgccggc
gtcccctacgtcacgcaggcgctgtcggatgccagcgggccggtggtcgccgtgtcggac
tggatgcgggcggttcccgagcagatccggccgtgggtgccgggcacctacgtgacgctg
ggcaccgacgggttcggcttctccgacacccggcccgcggcgcggcgctacttcaacacc
gacgcggagtcgcaggtggtcgcggtgctcgaggcgctggcgcgcgacggcgagatcgac
ccgtcggtgccggtcgccgccgcacgccagtaccgcatcgacgacgtgctggccgccccc
gagcagacgtccgaccccggcgtggcctaa
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